JP5252404B2 - ピラジン化合物、その使用及び調製方法 - Google Patents

ピラジン化合物、その使用及び調製方法 Download PDF

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JP5252404B2
JP5252404B2 JP2009524774A JP2009524774A JP5252404B2 JP 5252404 B2 JP5252404 B2 JP 5252404B2 JP 2009524774 A JP2009524774 A JP 2009524774A JP 2009524774 A JP2009524774 A JP 2009524774A JP 5252404 B2 JP5252404 B2 JP 5252404B2
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alkyl
compound
hydroxyl
substituted
alkoxy
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JP2010501003A5 (enExample
JP2010501003A (ja
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ティナ マリー モーウィック
アンソニー エス プロコポウィッツ
ワン マオ
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Transplantation (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009524774A 2006-08-16 2007-08-15 ピラジン化合物、その使用及び調製方法 Expired - Fee Related JP5252404B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82254606P 2006-08-16 2006-08-16
US60/822,546 2006-08-16
PCT/US2007/075946 WO2008022164A2 (en) 2006-08-16 2007-08-15 Pyrazine compounds, their use and methods of preparation

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JP2010501003A JP2010501003A (ja) 2010-01-14
JP2010501003A5 JP2010501003A5 (enExample) 2010-09-30
JP5252404B2 true JP5252404B2 (ja) 2013-07-31

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US (1) US8318723B2 (enExample)
EP (1) EP2061762B1 (enExample)
JP (1) JP5252404B2 (enExample)
AT (1) ATE517868T1 (enExample)
CA (1) CA2660560A1 (enExample)
WO (1) WO2008022164A2 (enExample)

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CN106967070A (zh) 2009-05-22 2017-07-21 因塞特控股公司 作为jak抑制剂的化合物
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