JP5250166B2 - Tof質量分析計用のイオン光学システム - Google Patents
Tof質量分析計用のイオン光学システム Download PDFInfo
- Publication number
- JP5250166B2 JP5250166B2 JP2001268393A JP2001268393A JP5250166B2 JP 5250166 B2 JP5250166 B2 JP 5250166B2 JP 2001268393 A JP2001268393 A JP 2001268393A JP 2001268393 A JP2001268393 A JP 2001268393A JP 5250166 B2 JP5250166 B2 JP 5250166B2
- Authority
- JP
- Japan
- Prior art keywords
- mass spectrometer
- tof mass
- spectrometer according
- lens
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003287 optical effect Effects 0.000 title claims description 18
- 238000000605 extraction Methods 0.000 claims description 92
- 150000002500 ions Chemical class 0.000 claims description 90
- 230000005684 electric field Effects 0.000 claims description 14
- 230000001133 acceleration Effects 0.000 claims description 13
- 238000009826 distribution Methods 0.000 claims description 10
- 238000001840 matrix-assisted laser desorption--ionisation time-of-flight mass spectrometry Methods 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 5
- 239000011521 glass Substances 0.000 claims description 5
- 230000035515 penetration Effects 0.000 claims description 5
- 239000004020 conductor Substances 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims 1
- 229910001220 stainless steel Inorganic materials 0.000 description 7
- 239000010935 stainless steel Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 229910052751 metal Inorganic materials 0.000 description 3
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- 238000004140 cleaning Methods 0.000 description 2
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- 230000004075 alteration Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
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- 238000010884 ion-beam technique Methods 0.000 description 1
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- 238000000816 matrix-assisted laser desorption--ionisation Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
Images
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/40—Time-of-flight spectrometers
- H01J49/403—Time-of-flight spectrometers characterised by the acceleration optics and/or the extraction fields
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/067—Ion lenses, apertures, skimmers
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0021902.2 | 2000-09-06 | ||
| GBGB0021902.2A GB0021902D0 (en) | 2000-09-06 | 2000-09-06 | Ion optics system for TOF mass spectrometer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002141016A JP2002141016A (ja) | 2002-05-17 |
| JP2002141016A5 JP2002141016A5 (enExample) | 2008-09-11 |
| JP5250166B2 true JP5250166B2 (ja) | 2013-07-31 |
Family
ID=9898981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001268393A Expired - Lifetime JP5250166B2 (ja) | 2000-09-06 | 2001-09-05 | Tof質量分析計用のイオン光学システム |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US6888129B2 (enExample) |
| EP (1) | EP1220288B1 (enExample) |
| JP (1) | JP5250166B2 (enExample) |
| GB (2) | GB0021902D0 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0021902D0 (en) * | 2000-09-06 | 2000-10-25 | Kratos Analytical Ltd | Ion optics system for TOF mass spectrometer |
| US6818887B2 (en) * | 2002-11-25 | 2004-11-16 | DRäGERWERK AKTIENGESELLSCHAFT | Reflector for a time-of-flight mass spectrometer |
| US7157701B2 (en) * | 2004-05-20 | 2007-01-02 | Mississippi State University Research And Technology Corporation | Compact time-of-flight mass spectrometer |
| US7067802B1 (en) * | 2005-02-11 | 2006-06-27 | Thermo Finnigan Llc | Generation of combination of RF and axial DC electric fields in an RF-only multipole |
| US7351959B2 (en) * | 2005-05-13 | 2008-04-01 | Applera Corporation | Mass analyzer systems and methods for their operation |
| US7385186B2 (en) * | 2005-05-13 | 2008-06-10 | Applera Corporation | Methods of operating ion optics for mass spectrometry |
| US7405396B2 (en) * | 2005-05-13 | 2008-07-29 | Applera Corporation | Sample handling mechanisms and methods for mass spectrometry |
| GB2462065B (en) | 2008-07-17 | 2013-03-27 | Kratos Analytical Ltd | TOF mass spectrometer for stigmatic imaging and associated method |
| WO2010111552A1 (en) * | 2009-03-27 | 2010-09-30 | Dh Technologies Development Pte. Ltd. | Heated time of flight source |
| JP5403509B2 (ja) * | 2009-04-17 | 2014-01-29 | 国立大学法人大阪大学 | イオン源および質量分析装置 |
| US8093565B2 (en) * | 2010-01-28 | 2012-01-10 | The United States of America as represented by the Adminstrator of the National Aeromautics and Space Administration | Wind and temperature spectrometer with crossed small-deflection energy analyzer |
| EP2569800A4 (en) * | 2010-05-11 | 2017-01-18 | DH Technologies Development Pte. Ltd. | An ion lens for reducing contaminant effects in an ion guide of a mass spectrometer |
| GB2486628B (en) * | 2010-08-02 | 2016-05-25 | Kratos Analytical Ltd | Methods and apparatuses for cleaning at least one surface of an ion source |
| CN103858205B (zh) * | 2011-10-03 | 2016-10-12 | 株式会社岛津制作所 | 飞行时间型质量分析装置 |
| JP2013101918A (ja) | 2011-10-13 | 2013-05-23 | Canon Inc | 質量分析装置 |
| GB201118270D0 (en) * | 2011-10-21 | 2011-12-07 | Shimadzu Corp | TOF mass analyser with improved resolving power |
| US9312092B2 (en) * | 2012-05-31 | 2016-04-12 | Siemens Aktiengesellschaft | Deflection plate and deflection device for deflecting charged particles |
| GB2533608B (en) * | 2014-12-23 | 2019-08-28 | Kratos Analytical Ltd | A time of flight mass spectrometer |
| CN107895684B (zh) * | 2017-12-14 | 2024-03-26 | 广州禾信康源医疗科技有限公司 | 离子源及质谱仪 |
| GB201808892D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Mass spectrometer |
| GB201808912D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Bench-top time of flight mass spectrometer |
| GB201808936D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Bench-top time of flight mass spectrometer |
| GB201808890D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Bench-top time of flight mass spectrometer |
| GB2576077B (en) | 2018-05-31 | 2021-12-01 | Micromass Ltd | Mass spectrometer |
| GB201808949D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Bench-top time of flight mass spectrometer |
| GB201808894D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Mass spectrometer |
| GB201808893D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Bench-top time of flight mass spectrometer |
| US11373849B2 (en) | 2018-05-31 | 2022-06-28 | Micromass Uk Limited | Mass spectrometer having fragmentation region |
| GB201808932D0 (en) | 2018-05-31 | 2018-07-18 | Micromass Ltd | Bench-top time of flight mass spectrometer |
| GB201810824D0 (en) | 2018-06-01 | 2018-08-15 | Micromass Ltd | An outer source assembly and associated components |
| GB2625377A (en) * | 2022-12-16 | 2024-06-19 | Thermo Fisher Scient Bremen Gmbh | Interface Ion guide |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1580234A (enExample) * | 1968-05-15 | 1969-09-05 | ||
| DE2739828C2 (de) * | 1977-09-03 | 1986-07-03 | Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München | Einrichtung zur Analyse von Proben |
| JPS6220231A (ja) * | 1985-07-18 | 1987-01-28 | Seiko Instr & Electronics Ltd | Icp質量分析装置 |
| US4864130A (en) * | 1986-06-04 | 1989-09-05 | Arch Development Corporation | Photo ion spectrometer |
| DE3718244A1 (de) * | 1987-05-30 | 1988-12-08 | Grix Raimund | Speicherionenquelle fuer flugzeit-massenspektrometer |
| GB2236186B (en) * | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| GB2250858B (en) * | 1990-10-22 | 1994-11-30 | Kratos Analytical Ltd | Charged particle extraction arrangement |
| DE4220802A1 (de) | 1992-06-25 | 1994-01-05 | Bosch Gmbh Robert | Vorrichtung zum Auflöten von Bauelementen auf Platinen |
| DE4322102C2 (de) * | 1993-07-02 | 1995-08-17 | Bergmann Thorald | Flugzeit-Massenspektrometer mit Gasphasen-Ionenquelle |
| AU2622195A (en) * | 1994-05-31 | 1995-12-21 | University Of Warwick | Tandem mass spectrometry apparatus |
| US5495108A (en) * | 1994-07-11 | 1996-02-27 | Hewlett-Packard Company | Orthogonal ion sampling for electrospray LC/MS |
| JP3549005B2 (ja) | 1994-08-31 | 2004-08-04 | 株式会社トプコン | 電界放出型電子銃 |
| JPH08148116A (ja) * | 1994-11-18 | 1996-06-07 | Hitachi Ltd | 顕微レーザ飛行時間型質量分析計 |
| US5614711A (en) * | 1995-05-04 | 1997-03-25 | Indiana University Foundation | Time-of-flight mass spectrometer |
| DE19520276C2 (de) * | 1995-06-02 | 1999-08-26 | Bruker Daltonik Gmbh | Vorrichtung für die Einführung von Ionen in ein Massenspektrometer |
| US5742049A (en) | 1995-12-21 | 1998-04-21 | Bruker-Franzen Analytik Gmbh | Method of improving mass resolution in time-of-flight mass spectrometry |
| JP3424431B2 (ja) * | 1996-03-29 | 2003-07-07 | 株式会社日立製作所 | 質量分析装置 |
| US5777325A (en) * | 1996-05-06 | 1998-07-07 | Hewlett-Packard Company | Device for time lag focusing time-of-flight mass spectrometry |
| JP3643917B2 (ja) * | 1996-05-17 | 2005-04-27 | 株式会社ルネサステクノロジ | 顕微レーザ質量分析計 |
| JPH09326243A (ja) * | 1996-06-05 | 1997-12-16 | Shimadzu Corp | Maldi−tof質量分析装置 |
| JPH10172506A (ja) * | 1997-09-19 | 1998-06-26 | United States Department Of Energ | フォトイオン分光計 |
| GB9807915D0 (en) * | 1998-04-14 | 1998-06-10 | Shimadzu Res Lab Europe Ltd | Apparatus for production and extraction of charged particles |
| US5965884A (en) * | 1998-06-04 | 1999-10-12 | The Regents Of The University Of California | Atmospheric pressure matrix assisted laser desorption |
| CA2344446C (en) * | 1998-09-23 | 2008-07-08 | Varian Australia Pty. Ltd. | Ion optical system for a mass spectrometer |
| GB0021902D0 (en) * | 2000-09-06 | 2000-10-25 | Kratos Analytical Ltd | Ion optics system for TOF mass spectrometer |
-
2000
- 2000-09-06 GB GBGB0021902.2A patent/GB0021902D0/en not_active Ceased
-
2001
- 2001-08-29 EP EP01307313.5A patent/EP1220288B1/en not_active Expired - Lifetime
- 2001-08-29 GB GB0120893A patent/GB2368715B/en not_active Expired - Lifetime
- 2001-09-05 JP JP2001268393A patent/JP5250166B2/ja not_active Expired - Lifetime
- 2001-09-06 US US09/946,823 patent/US6888129B2/en not_active Expired - Lifetime
-
2004
- 2004-07-21 US US10/895,476 patent/US7041970B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1220288B1 (en) | 2019-05-22 |
| GB2368715B (en) | 2004-10-06 |
| US7041970B2 (en) | 2006-05-09 |
| GB0120893D0 (en) | 2001-10-17 |
| US20020036262A1 (en) | 2002-03-28 |
| US6888129B2 (en) | 2005-05-03 |
| EP1220288A3 (en) | 2005-08-31 |
| GB2368715A (en) | 2002-05-08 |
| EP1220288A2 (en) | 2002-07-03 |
| US20040256549A1 (en) | 2004-12-23 |
| GB0021902D0 (en) | 2000-10-25 |
| JP2002141016A (ja) | 2002-05-17 |
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