JP5243774B2 - Octシステムを備える眼科手術用顕微鏡 - Google Patents
Octシステムを備える眼科手術用顕微鏡 Download PDFInfo
- Publication number
- JP5243774B2 JP5243774B2 JP2007290532A JP2007290532A JP5243774B2 JP 5243774 B2 JP5243774 B2 JP 5243774B2 JP 2007290532 A JP2007290532 A JP 2007290532A JP 2007290532 A JP2007290532 A JP 2007290532A JP 5243774 B2 JP5243774 B2 JP 5243774B2
- Authority
- JP
- Japan
- Prior art keywords
- oct
- optical path
- microscope
- oct system
- scanning
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000003287 optical effect Effects 0.000 claims description 144
- 238000007689 inspection Methods 0.000 claims description 10
- 238000001356 surgical procedure Methods 0.000 claims description 7
- 238000012014 optical coherence tomography Methods 0.000 description 197
- 230000005855 radiation Effects 0.000 description 24
- 239000000835 fiber Substances 0.000 description 8
- 238000005286 illumination Methods 0.000 description 8
- 238000003384 imaging method Methods 0.000 description 3
- 230000001427 coherent effect Effects 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/13—Ophthalmic microscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
- G01B9/02007—Two or more frequencies or sources used for interferometric measurement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02015—Interferometers characterised by the beam path configuration
- G01B9/02027—Two or more interferometric channels or interferometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02034—Interferometers characterised by particularly shaped beams or wavefronts
- G01B9/02035—Shaping the focal point, e.g. elongated focus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/0209—Low-coherence interferometers
- G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/20—Surgical microscopes characterised by non-optical aspects
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/008—Details of detection or image processing, including general computer control
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Radiology & Medical Imaging (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Eye Examination Apparatus (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Microscoopes, Condenser (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006052513 | 2006-11-06 | ||
| DE102007019680.8 | 2007-04-24 | ||
| DE102007019680A DE102007019680A1 (de) | 2006-11-06 | 2007-04-24 | Ophthalmo-Operationsmikroskop mit OCT-System |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012282434A Division JP5587395B2 (ja) | 2007-04-24 | 2012-12-26 | Octシステムを備える眼科手術用顕微鏡 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008268852A JP2008268852A (ja) | 2008-11-06 |
| JP2008268852A5 JP2008268852A5 (enExample) | 2010-12-24 |
| JP5243774B2 true JP5243774B2 (ja) | 2013-07-24 |
Family
ID=38926425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007290532A Active JP5243774B2 (ja) | 2006-11-06 | 2007-11-08 | Octシステムを備える眼科手術用顕微鏡 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7839494B2 (enExample) |
| EP (2) | EP2482113B1 (enExample) |
| JP (1) | JP5243774B2 (enExample) |
| DE (1) | DE102007019680A1 (enExample) |
| ES (2) | ES2399353T3 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7952722B2 (en) * | 2007-12-12 | 2011-05-31 | Kabushiki Kaisha Topcon | Optical image measurement device |
| EP2103249B9 (en) | 2008-03-19 | 2016-10-19 | Carl Zeiss Meditec AG | Surgical microscopy system having an optical coherence tomography facility |
| DE102008041284B4 (de) * | 2008-05-07 | 2010-05-27 | Carl Zeiss Surgical Gmbh | Ophthalmo-Operationsmikroskopsystem mit OCT-Messeinrichtung |
| US8459795B2 (en) | 2008-09-16 | 2013-06-11 | Carl Zeiss Meditec Ag | Measuring system for ophthalmic surgery |
| EP2335560B1 (en) | 2008-10-17 | 2014-11-26 | Olympus Medical Systems Corp. | Endoscope system and endoscopic image processing apparatus |
| JP5632386B2 (ja) * | 2008-11-26 | 2014-11-26 | カール ツアイス メディテック アクチエンゲゼルシャフト | 画像化システム |
| DE102008059876B4 (de) * | 2008-12-01 | 2010-08-05 | Carl Zeiss Surgical Gmbh | Ophthalmoskopie-System und Ophthalmoskopie-Verfahren |
| DE102009037708B4 (de) | 2009-08-17 | 2019-02-21 | Carl Zeiss Meditec Ag | Erzeugnis zur Verwendung in einem OCT-Verfahren und Intraokularlinse |
| US8287126B2 (en) | 2010-01-15 | 2012-10-16 | Carl Zeiss Meditec Ag | System and method for visualizing objects |
| US8366271B2 (en) | 2010-01-20 | 2013-02-05 | Duke University | Systems and methods for surgical microscope and optical coherence tomography (OCT) imaging |
| JP2011212432A (ja) * | 2010-03-15 | 2011-10-27 | Nidek Co Ltd | 眼科撮影装置 |
| DE102011114523A1 (de) * | 2011-09-29 | 2013-04-04 | Carl Zeiss Meditec Ag | Modul zur Weiterleitung eines Lichtstrahls |
| EP2786697A4 (en) * | 2011-12-01 | 2015-08-26 | Kyungpook Nat Univ Ind Acad | MICROSCOPE FOR MONITORING OPTICAL COHERENCE TOMOGRAPHY |
| WO2013085997A1 (en) | 2011-12-05 | 2013-06-13 | Bioptigen, Inc. | Optical imaging systems having input beam shape control and path length control |
| US8777412B2 (en) | 2012-04-05 | 2014-07-15 | Bioptigen, Inc. | Surgical microscopes using optical coherence tomography and related methods |
| WO2014197553A2 (en) | 2013-06-04 | 2014-12-11 | Bioptigen, Inc. | Hybrid telescope for optical beam delivery and related systems and methods |
| JP6415553B2 (ja) | 2013-07-29 | 2018-10-31 | バイオプティジェン, インコーポレイテッドBioptigen, Inc. | 外科手術用手技光干渉断層計及び関連するシステム及びその方法 |
| EP3039474A1 (en) | 2013-08-28 | 2016-07-06 | Bioptigen, Inc. | Heads up displays for optical coherence tomography integrated surgical microscopes |
| DE102013219379B3 (de) | 2013-09-26 | 2015-03-12 | Carl Zeiss Meditec Ag | Optisches Abbildungssystem |
| DE102013219383B3 (de) | 2013-09-26 | 2015-03-12 | Carl Zeiss Meditec Ag | Optisches Abbildungssystem |
| EP2921099A1 (de) * | 2014-03-18 | 2015-09-23 | Dieter Mann GmbH | Ophthalmoskopie-Vorsatzeinheit für Operationsmikroskop |
| EP2997880B1 (en) * | 2014-09-19 | 2019-02-06 | Carl Zeiss Meditec AG | Optical system, comprising a microscopy system and an oct system |
| US10835119B2 (en) | 2015-02-05 | 2020-11-17 | Duke University | Compact telescope configurations for light scanning systems and methods of using the same |
| WO2016127088A1 (en) | 2015-02-06 | 2016-08-11 | Duke University | Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope |
| JP6456711B2 (ja) | 2015-02-16 | 2019-01-23 | 株式会社トプコン | 眼科手術用顕微鏡および眼科手術用アタッチメント |
| JP2016202453A (ja) * | 2015-04-20 | 2016-12-08 | 株式会社トプコン | 眼科手術用顕微鏡 |
| US9693686B2 (en) * | 2015-04-30 | 2017-07-04 | Novartis Ag | Ophthalmic visualization devices, systems, and methods |
| US10694939B2 (en) | 2016-04-29 | 2020-06-30 | Duke University | Whole eye optical coherence tomography(OCT) imaging systems and related methods |
| DE102017105580B4 (de) * | 2016-11-04 | 2025-10-02 | Carl Zeiss Meditec Ag | Operationsmikroskop |
| JP7042663B2 (ja) * | 2017-03-30 | 2022-03-28 | 株式会社トプコン | 眼科用顕微鏡 |
| WO2018203577A1 (ja) | 2017-05-02 | 2018-11-08 | 株式会社トプコン | 眼科用顕微鏡及び機能拡張ユニット |
| CA3055684A1 (en) | 2017-05-02 | 2018-11-08 | Novartis Ag | Reconfigurable optical coherence tomography (oct) system |
| EP3636137B1 (en) | 2017-05-25 | 2024-04-17 | Topcon Corporation | Ophthalmic microscope and function expansion unit |
| WO2018216788A1 (ja) | 2017-05-25 | 2018-11-29 | 株式会社トプコン | 眼科用顕微鏡及び機能拡張ユニット |
| JP7329308B2 (ja) * | 2017-07-05 | 2023-08-18 | 株式会社ニデック | Oct装置および光学アタッチメント |
| KR101931540B1 (ko) * | 2017-07-31 | 2018-12-24 | 주식회사 고영테크놀러지 | 스테레오 현미경, 광학 장치 및 이를 이용한 광경로 형성 방법 |
| JP7213378B2 (ja) * | 2017-08-31 | 2023-01-26 | 株式会社トプコン | Oct機能拡張ユニット |
| CN108852617B (zh) * | 2018-05-18 | 2021-06-25 | 深圳市斯尔顿科技有限公司 | 一种眼科手术显微镜系统 |
| CN108577802B (zh) * | 2018-05-18 | 2021-02-26 | 深圳市斯尔顿科技有限公司 | 结合oct成像的眼科手术显微镜系统 |
| JP6638050B2 (ja) * | 2018-10-23 | 2020-01-29 | 株式会社トプコン | 眼科手術用顕微鏡および眼科手術用アタッチメント |
| CN110231623A (zh) * | 2019-04-22 | 2019-09-13 | 电子科技大学 | 一种探测等离子体性质的准光光路装置 |
| CN110793465B (zh) * | 2019-11-07 | 2021-07-20 | 中国计量大学 | 一种微透射元件多面形大动态范围同步测量方法 |
| CN115634098B (zh) * | 2022-10-25 | 2023-08-01 | 重庆贝奥新视野医疗设备有限公司 | 一种高速眼科手术导航oct系统及实现方法 |
| CN116548911B (zh) * | 2023-05-19 | 2023-12-08 | 北京至真互联网技术有限公司 | 一种基于oct技术的眼部血管成像方法及系统 |
| DE102024107408A1 (de) * | 2024-03-15 | 2025-09-18 | Carl Zeiss Meditec Ag | Verfahren zum Fokussieren eines optischen Augenbeobachtungsgeräts und optisches Beobachtungsgerät |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69227902T3 (de) | 1991-04-29 | 2010-04-22 | Massachusetts Institute Of Technology, Cambridge | Vorrichtung für optische abbildung und messung |
| US5535052A (en) * | 1992-07-24 | 1996-07-09 | Carl-Zeiss-Stiftung | Laser microscope |
| US5493109A (en) * | 1994-08-18 | 1996-02-20 | Carl Zeiss, Inc. | Optical coherence tomography assisted ophthalmologic surgical microscope |
| ES2180597T4 (es) * | 1994-08-18 | 2003-07-01 | Zeiss Carl | Aparato quirurgico asistido por tomografia de coherencia optica. |
| DE9415219U1 (de) * | 1994-09-22 | 1994-11-24 | Oculus Optikgeräte GmbH, 35582 Wetzlar | Vorsatzeinrichtung für ein Mikroskop |
| CH693804A5 (de) * | 1994-10-13 | 2004-02-13 | Zeiss Carl Fa | Beleuchtungseinrichtung für ein Stereomikroskop. |
| US5795295A (en) * | 1996-06-25 | 1998-08-18 | Carl Zeiss, Inc. | OCT-assisted surgical microscope with multi-coordinate manipulator |
| ES2183447T3 (es) * | 1998-03-09 | 2003-03-16 | Medizinisches Laserzentrum Lub | Procedimiento y dispositivo destinados a examinar un segmento ocular. |
| JP2001108906A (ja) * | 1999-10-01 | 2001-04-20 | Topcon Corp | 手術用顕微鏡 |
| DE10140402B4 (de) * | 2000-09-26 | 2012-08-30 | Carl Zeiss Meditec Ag | Bildumkehrsystem, Ophthalmoskopie-Vorsatzmodul und Operationsmikroskop |
| DE10064909A1 (de) * | 2000-12-23 | 2002-07-04 | Leica Microsystems | Einrichtung zur Helligkeitssteuerung von überlagerten Zusatzinformationen in einer optischen Betrachtungseinrichtung |
| DE10110389A1 (de) * | 2001-03-03 | 2002-09-12 | Zeiss Carl | Verfahren zur Justierung einer Lampe relativ zu einem Beleuchtungsstrahlengang eines Mikroskopes und zur Ausführung des Verfahrens geeignetes Mikroskop |
| US6726325B2 (en) * | 2002-02-26 | 2004-04-27 | Carl Zeiss Meditec, Inc. | Tracking assisted optical coherence tomography |
| US6741359B2 (en) * | 2002-05-22 | 2004-05-25 | Carl Zeiss Meditec, Inc. | Optical coherence tomography optical scanner |
| DE10302401A1 (de) * | 2003-01-21 | 2004-07-29 | Leica Microsystems (Schweiz) Ag | Operationsmikroskop |
| US7423807B2 (en) * | 2003-07-17 | 2008-09-09 | Leica Microsystems (Schweiz) Ag | Ophthalmoscopic stereomicroscope with correction component |
| WO2006010379A1 (en) | 2004-07-29 | 2006-02-02 | Actelion Pharmaceuticals Ltd. | Novel thiophene derivatives as immunosuppressive agents |
| DE102004049368A1 (de) | 2004-10-09 | 2006-04-13 | Carl Zeiss Ag | Operationsmikroskop mit Binokulartubus für Mitbeobachtung |
| US20060176550A1 (en) * | 2005-02-07 | 2006-08-10 | Christian Luecke | Tube for a viewing device as well as a viewing device |
| WO2006100544A1 (en) | 2005-03-21 | 2006-09-28 | Ecole Polytechnique Federale De Lausanne (Epfl) | Phase sensitive fourier domain optical coherence tomography |
| US8064989B2 (en) * | 2005-09-29 | 2011-11-22 | Bioptigen, Inc. | Portable optical coherence tomography (OCT) devices and related systems |
| JP2007230834A (ja) * | 2006-03-02 | 2007-09-13 | Konica Minolta Opto Inc | 光学ガラス素子の成形方法 |
| JP5450377B2 (ja) * | 2007-03-20 | 2014-03-26 | トプコン・ユーロペ・メディカル・ビーブイ. | 眼を観察するための装置と装置において使用するためのoctモジュール |
-
2007
- 2007-04-24 DE DE102007019680A patent/DE102007019680A1/de not_active Ceased
- 2007-10-10 ES ES07019795T patent/ES2399353T3/es active Active
- 2007-10-10 EP EP12165225.9A patent/EP2482113B1/de active Active
- 2007-10-10 EP EP07019795A patent/EP1918755B1/de not_active Revoked
- 2007-10-10 ES ES12165225.9T patent/ES2662717T3/es active Active
- 2007-11-08 JP JP2007290532A patent/JP5243774B2/ja active Active
- 2007-11-21 US US11/984,819 patent/US7839494B2/en active Active
-
2010
- 2010-08-04 US US12/805,518 patent/US8023120B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2482113A1 (de) | 2012-08-01 |
| ES2662717T3 (es) | 2018-04-09 |
| US8023120B2 (en) | 2011-09-20 |
| US20080117432A1 (en) | 2008-05-22 |
| ES2399353T3 (es) | 2013-03-27 |
| EP1918755B1 (de) | 2012-12-05 |
| EP1918755A1 (de) | 2008-05-07 |
| US7839494B2 (en) | 2010-11-23 |
| US20100309478A1 (en) | 2010-12-09 |
| DE102007019680A1 (de) | 2008-05-08 |
| JP2008268852A (ja) | 2008-11-06 |
| EP2482113B1 (de) | 2017-12-27 |
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Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101108 |
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| A621 | Written request for application examination |
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