JP5174655B2 - 心臓周期に同期化される神経刺激器 - Google Patents

心臓周期に同期化される神経刺激器 Download PDF

Info

Publication number
JP5174655B2
JP5174655B2 JP2008505371A JP2008505371A JP5174655B2 JP 5174655 B2 JP5174655 B2 JP 5174655B2 JP 2008505371 A JP2008505371 A JP 2008505371A JP 2008505371 A JP2008505371 A JP 2008505371A JP 5174655 B2 JP5174655 B2 JP 5174655B2
Authority
JP
Japan
Prior art keywords
signal
hemodynamic
neural stimulation
cardiac
predetermined type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2008505371A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008534218A (ja
JP2008534218A5 (enExample
Inventor
リバス，イマッド
ハフナー，ポール・エイ
マッカベ，アーロン
ツアン，イ
Original Assignee
カーディアック ペースメイカーズ， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カーディアック ペースメイカーズ， インコーポレイテッド filed Critical カーディアック ペースメイカーズ， インコーポレイテッド
Publication of JP2008534218A publication Critical patent/JP2008534218A/ja
Publication of JP2008534218A5 publication Critical patent/JP2008534218A5/ja
Application granted granted Critical
Publication of JP5174655B2 publication Critical patent/JP5174655B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
    • A61N1/36542—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by body motion, e.g. acceleration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
    • A61N1/36564—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
    • A61N1/36571—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by blood flow rate, e.g. blood velocity or cardiac output

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
JP2008505371A 2005-04-05 2006-03-29 心臓周期に同期化される神経刺激器 Expired - Fee Related JP5174655B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/099,141 2005-04-05
US11/099,141 US7542800B2 (en) 2005-04-05 2005-04-05 Method and apparatus for synchronizing neural stimulation to cardiac cycles
PCT/US2006/011446 WO2006107675A1 (en) 2005-04-05 2006-03-29 Cardiac cycle - synchronized neural stimulator

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012243472A Division JP2013059633A (ja) 2005-04-05 2012-11-05 神経刺激システム

Publications (3)

Publication Number Publication Date
JP2008534218A JP2008534218A (ja) 2008-08-28
JP2008534218A5 JP2008534218A5 (enExample) 2009-05-21
JP5174655B2 true JP5174655B2 (ja) 2013-04-03

Family

ID=36764624

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008505371A Expired - Fee Related JP5174655B2 (ja) 2005-04-05 2006-03-29 心臓周期に同期化される神経刺激器
JP2012243472A Pending JP2013059633A (ja) 2005-04-05 2012-11-05 神経刺激システム

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012243472A Pending JP2013059633A (ja) 2005-04-05 2012-11-05 神経刺激システム

Country Status (4)

Country Link
US (3) US7542800B2 (enExample)
EP (1) EP1871464B1 (enExample)
JP (2) JP5174655B2 (enExample)
WO (1) WO2006107675A1 (enExample)

Families Citing this family (208)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6584362B1 (en) 2000-08-30 2003-06-24 Cardiac Pacemakers, Inc. Leads for pacing and/or sensing the heart from within the coronary veins
US20080077192A1 (en) 2002-05-03 2008-03-27 Afferent Corporation System and method for neuro-stimulation
US7189204B2 (en) 2002-12-04 2007-03-13 Cardiac Pacemakers, Inc. Sleep detection using an adjustable threshold
US8606356B2 (en) 2003-09-18 2013-12-10 Cardiac Pacemakers, Inc. Autonomic arousal detection system and method
US8002553B2 (en) 2003-08-18 2011-08-23 Cardiac Pacemakers, Inc. Sleep quality data collection and evaluation
WO2005028029A2 (en) 2003-08-18 2005-03-31 Cardiac Pacemakers, Inc. Patient monitoring, diagnosis, and/or therapy systems and methods
US7887493B2 (en) * 2003-09-18 2011-02-15 Cardiac Pacemakers, Inc. Implantable device employing movement sensing for detecting sleep-related disorders
US7783353B2 (en) 2003-12-24 2010-08-24 Cardiac Pacemakers, Inc. Automatic neural stimulation modulation based on activity and circadian rhythm
US8200331B2 (en) 2004-11-04 2012-06-12 Cardiac Pacemakers, Inc. System and method for filtering neural stimulation
US7873413B2 (en) * 2006-07-24 2011-01-18 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US8126559B2 (en) 2004-11-30 2012-02-28 Cardiac Pacemakers, Inc. Neural stimulation with avoidance of inappropriate stimulation
US7706884B2 (en) 2003-12-24 2010-04-27 Cardiac Pacemakers, Inc. Baroreflex stimulation synchronized to circadian rhythm
US7486991B2 (en) 2003-12-24 2009-02-03 Cardiac Pacemakers, Inc. Baroreflex modulation to gradually decrease blood pressure
US7869881B2 (en) 2003-12-24 2011-01-11 Cardiac Pacemakers, Inc. Baroreflex stimulator with integrated pressure sensor
US20080015659A1 (en) * 2003-12-24 2008-01-17 Yi Zhang Neurostimulation systems and methods for cardiac conditions
US8126560B2 (en) 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US20050149132A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US9020595B2 (en) 2003-12-24 2015-04-28 Cardiac Pacemakers, Inc. Baroreflex activation therapy with conditional shut off
US7460906B2 (en) 2003-12-24 2008-12-02 Cardiac Pacemakers, Inc. Baroreflex stimulation to treat acute myocardial infarction
US7643875B2 (en) 2003-12-24 2010-01-05 Cardiac Pacemakers, Inc. Baroreflex stimulation system to reduce hypertension
US7509166B2 (en) 2003-12-24 2009-03-24 Cardiac Pacemakers, Inc. Automatic baroreflex modulation responsive to adverse event
US20050149133A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Sensing with compensation for neural stimulator
US8024050B2 (en) 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US7747323B2 (en) 2004-06-08 2010-06-29 Cardiac Pacemakers, Inc. Adaptive baroreflex stimulation therapy for disordered breathing
US7596413B2 (en) 2004-06-08 2009-09-29 Cardiac Pacemakers, Inc. Coordinated therapy for disordered breathing including baroreflex modulation
US8175705B2 (en) * 2004-10-12 2012-05-08 Cardiac Pacemakers, Inc. System and method for sustained baroreflex stimulation
US7587238B2 (en) 2005-03-11 2009-09-08 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
US7840266B2 (en) * 2005-03-11 2010-11-23 Cardiac Pacemakers, Inc. Integrated lead for applying cardiac resynchronization therapy and neural stimulation therapy
US7660628B2 (en) 2005-03-23 2010-02-09 Cardiac Pacemakers, Inc. System to provide myocardial and neural stimulation
US8473049B2 (en) 2005-05-25 2013-06-25 Cardiac Pacemakers, Inc. Implantable neural stimulator with mode switching
US7555341B2 (en) 2005-04-05 2009-06-30 Cardiac Pacemakers, Inc. System to treat AV-conducted ventricular tachyarrhythmia
US7493161B2 (en) 2005-05-10 2009-02-17 Cardiac Pacemakers, Inc. System and method to deliver therapy in presence of another therapy
US7542800B2 (en) 2005-04-05 2009-06-02 Cardiac Pacemakers, Inc. Method and apparatus for synchronizing neural stimulation to cardiac cycles
US8406876B2 (en) 2005-04-05 2013-03-26 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US7881782B2 (en) * 2005-04-20 2011-02-01 Cardiac Pacemakers, Inc. Neural stimulation system to prevent simultaneous energy discharges
US8784336B2 (en) 2005-08-24 2014-07-22 C. R. Bard, Inc. Stylet apparatuses and methods of manufacture
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US7711430B2 (en) * 2006-02-10 2010-05-04 Electrocore Llc Methods and apparatus for treating anaphylaxis using electrical modulation
EP3069752B1 (en) 2006-03-29 2018-03-28 Dignity Health Microburst electrical stimulation of cranial nerves for the treatment of medical conditions
US8457734B2 (en) 2006-08-29 2013-06-04 Cardiac Pacemakers, Inc. System and method for neural stimulation
US8388546B2 (en) 2006-10-23 2013-03-05 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
US7794407B2 (en) 2006-10-23 2010-09-14 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
US8364263B2 (en) 2006-10-26 2013-01-29 Cardiac Pacemakers, Inc. System and method for systolic interval analysis
EP2094352A4 (en) 2006-12-06 2010-05-19 Cleveland Clinic Foundation METHOD AND SYSTEM FOR TREATING ACUTE CARDIAC INSUFFICIENCY BY NEUROMODULATION
US10716528B2 (en) 2007-03-08 2020-07-21 Sync-Rx, Ltd. Automatic display of previously-acquired endoluminal images
WO2010058398A2 (en) 2007-03-08 2010-05-27 Sync-Rx, Ltd. Image processing and tool actuation for medical procedures
US9629571B2 (en) 2007-03-08 2017-04-25 Sync-Rx, Ltd. Co-use of endoluminal data and extraluminal imaging
WO2008107905A2 (en) 2007-03-08 2008-09-12 Sync-Rx, Ltd. Imaging and tools for use with moving organs
US8700130B2 (en) 2007-03-08 2014-04-15 Sync-Rx, Ltd. Stepwise advancement of a medical tool
US9968256B2 (en) 2007-03-08 2018-05-15 Sync-Rx Ltd. Automatic identification of a tool
US9375164B2 (en) 2007-03-08 2016-06-28 Sync-Rx, Ltd. Co-use of endoluminal data and extraluminal imaging
US11064964B2 (en) 2007-03-08 2021-07-20 Sync-Rx, Ltd Determining a characteristic of a lumen by measuring velocity of a contrast agent
US11197651B2 (en) 2007-03-08 2021-12-14 Sync-Rx, Ltd. Identification and presentation of device-to-vessel relative motion
US20080266118A1 (en) * 2007-03-09 2008-10-30 Pierson Nicholas J Personal emergency condition detection and safety systems and methods
US10449330B2 (en) 2007-11-26 2019-10-22 C. R. Bard, Inc. Magnetic element-equipped needle assemblies
US10524691B2 (en) 2007-11-26 2020-01-07 C. R. Bard, Inc. Needle assembly including an aligned magnetic element
US10751509B2 (en) 2007-11-26 2020-08-25 C. R. Bard, Inc. Iconic representations for guidance of an indwelling medical device
EP2712547B1 (en) 2007-11-26 2015-09-30 C. R. Bard, Inc. Integrated system for intravascular placement of a catheter
US9649048B2 (en) 2007-11-26 2017-05-16 C. R. Bard, Inc. Systems and methods for breaching a sterile field for intravascular placement of a catheter
US9521961B2 (en) 2007-11-26 2016-12-20 C. R. Bard, Inc. Systems and methods for guiding a medical instrument
US8781555B2 (en) 2007-11-26 2014-07-15 C. R. Bard, Inc. System for placement of a catheter including a signal-generating stylet
US8849382B2 (en) 2007-11-26 2014-09-30 C. R. Bard, Inc. Apparatus and display methods relating to intravascular placement of a catheter
US8478382B2 (en) 2008-02-11 2013-07-02 C. R. Bard, Inc. Systems and methods for positioning a catheter
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
WO2009134876A1 (en) 2008-04-29 2009-11-05 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US8768469B2 (en) 2008-08-08 2014-07-01 Enteromedics Inc. Systems for regulation of blood pressure and heart rate
EP2313143B1 (en) 2008-08-22 2014-09-24 C.R. Bard, Inc. Catheter assembly including ecg sensor and magnetic assemblies
US8437833B2 (en) 2008-10-07 2013-05-07 Bard Access Systems, Inc. Percutaneous magnetic gastrostomy
US11064903B2 (en) 2008-11-18 2021-07-20 Sync-Rx, Ltd Apparatus and methods for mapping a sequence of images to a roadmap image
US9101286B2 (en) 2008-11-18 2015-08-11 Sync-Rx, Ltd. Apparatus and methods for determining a dimension of a portion of a stack of endoluminal data points
US9144394B2 (en) 2008-11-18 2015-09-29 Sync-Rx, Ltd. Apparatus and methods for determining a plurality of local calibration factors for an image
US8855744B2 (en) 2008-11-18 2014-10-07 Sync-Rx, Ltd. Displaying a device within an endoluminal image stack
US10362962B2 (en) 2008-11-18 2019-07-30 Synx-Rx, Ltd. Accounting for skipped imaging locations during movement of an endoluminal imaging probe
US9095313B2 (en) 2008-11-18 2015-08-04 Sync-Rx, Ltd. Accounting for non-uniform longitudinal motion during movement of an endoluminal imaging probe
US9974509B2 (en) 2008-11-18 2018-05-22 Sync-Rx Ltd. Image super enhancement
US8632534B2 (en) 2009-04-03 2014-01-21 Angiodynamics, Inc. Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
WO2010138919A2 (en) * 2009-05-28 2010-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
BRPI1010773B1 (pt) 2009-06-12 2021-06-01 Bard Access Systems, Inc Adaptador para eletrocardiografia endovascular referência cruzada para pedidos relacionados
US9532724B2 (en) 2009-06-12 2017-01-03 Bard Access Systems, Inc. Apparatus and method for catheter navigation using endovascular energy mapping
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
EP2464407A4 (en) 2009-08-10 2014-04-02 Bard Access Systems Inc DEVICES AND METHODS FOR ENDOVASCULAR ELECTROGRAPHY
CN102665541B (zh) 2009-09-29 2016-01-13 C·R·巴德股份有限公司 与用于导管的血管内放置的设备一起使用的探针
US11103213B2 (en) 2009-10-08 2021-08-31 C. R. Bard, Inc. Spacers for use with an ultrasound probe
EP2509683B1 (en) 2009-12-08 2017-08-23 Cardiac Pacemakers, Inc. Concurrent therapy detection in implantable medical devices
JP2013518676A (ja) 2010-02-02 2013-05-23 シー・アール・バード・インコーポレーテッド カテーテルナビゲーションおよびチップの位置を特定するための装置および方法
EP2531257B1 (en) * 2010-02-03 2015-10-14 Cardiac Pacemakers, Inc. Sympathetic stimulation for improved myocardial relaxation
US8423134B2 (en) 2010-04-29 2013-04-16 Medtronic, Inc. Therapy using perturbation and effect of physiological systems
US8639327B2 (en) 2010-04-29 2014-01-28 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US8620425B2 (en) 2010-04-29 2013-12-31 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
ES2778041T3 (es) 2010-05-28 2020-08-07 Bard Inc C R Aparato para su uso con sistema de guiado de inserción de aguja
EP2912999B1 (en) 2010-05-28 2022-06-29 C. R. Bard, Inc. Apparatus for use with needle insertion guidance system
CN103228219B (zh) 2010-08-09 2016-04-27 C·R·巴德股份有限公司 用于超声探测器头的支撑和覆盖结构
US20120046562A1 (en) 2010-08-20 2012-02-23 C. R. Bard, Inc. Reconfirmation of ecg-assisted catheter tip placement
JP5669487B2 (ja) * 2010-09-09 2015-02-12 オリンパス株式会社 神経刺激装置
JP5566228B2 (ja) * 2010-09-10 2014-08-06 オリンパス株式会社 神経刺激装置
JP5616731B2 (ja) * 2010-09-21 2014-10-29 オリンパス株式会社 神経刺激パラメータ検出装置および神経刺激装置
WO2012051433A2 (en) 2010-10-13 2012-04-19 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
CN103189009B (zh) 2010-10-29 2016-09-07 C·R·巴德股份有限公司 医疗设备的生物阻抗辅助放置
WO2012088149A2 (en) 2010-12-20 2012-06-28 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US8718763B2 (en) 2011-01-19 2014-05-06 Medtronic, Inc. Vagal stimulation
US8706223B2 (en) 2011-01-19 2014-04-22 Medtronic, Inc. Preventative vagal stimulation
US8781582B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US8725259B2 (en) 2011-01-19 2014-05-13 Medtronic, Inc. Vagal stimulation
US8781583B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
JP5695480B2 (ja) * 2011-04-26 2015-04-08 オリンパス株式会社 神経刺激装置および神経刺激装置の作動方法
EP2723231A4 (en) 2011-06-23 2015-02-25 Sync Rx Ltd LUMINAL BACKGROUND CLEANING
JP6008960B2 (ja) 2011-07-06 2016-10-19 シー・アール・バード・インコーポレーテッドＣ Ｒ Ｂａｒｄ Ｉｎｃｏｒｐｏｒａｔｅｄ 挿入案内システムのためのニードル長決定および較正
JP5881326B2 (ja) 2011-07-08 2016-03-09 オリンパス株式会社 神経刺激装置、神経刺激システムおよび神経刺激装置の制御方法
USD699359S1 (en) 2011-08-09 2014-02-11 C. R. Bard, Inc. Ultrasound probe head
USD724745S1 (en) 2011-08-09 2015-03-17 C. R. Bard, Inc. Cap for an ultrasound probe
JP2014522713A (ja) 2011-08-10 2014-09-08 カーディアック ペースメイカーズ， インコーポレイテッド 頚部インピーダンスを使用する生理学的パラメータの判定
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
US9211107B2 (en) 2011-11-07 2015-12-15 C. R. Bard, Inc. Ruggedized ultrasound hydrogel insert
EP2785412B1 (en) 2011-11-29 2017-07-12 Cardiac Pacemakers, Inc. Autonomic modulation using peripheral nerve field stimulation
US8600505B2 (en) 2011-12-07 2013-12-03 Cyberonics, Inc. Implantable device for facilitating control of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8918190B2 (en) 2011-12-07 2014-12-23 Cyberonics, Inc. Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction
US8630709B2 (en) 2011-12-07 2014-01-14 Cyberonics, Inc. Computer-implemented system and method for selecting therapy profiles of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8918191B2 (en) 2011-12-07 2014-12-23 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
US10188856B1 (en) 2011-12-07 2019-01-29 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8577458B1 (en) 2011-12-07 2013-11-05 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with leadless heart rate monitoring
US9050014B2 (en) 2011-12-14 2015-06-09 Siemens Medical Solutions Usa, Inc. System for cardiac arrhythmia detection and characterization
US8700150B2 (en) 2012-01-17 2014-04-15 Cyberonics, Inc. Implantable neurostimulator for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
US8571654B2 (en) 2012-01-17 2013-10-29 Cyberonics, Inc. Vagus nerve neurostimulator with multiple patient-selectable modes for treating chronic cardiac dysfunction
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
JP5856876B2 (ja) * 2012-03-06 2016-02-10 オリンパス株式会社 心臓治療装置とその作動方法
US10820885B2 (en) 2012-06-15 2020-11-03 C. R. Bard, Inc. Apparatus and methods for detection of a removable cap on an ultrasound probe
EP2863802B1 (en) 2012-06-26 2020-11-04 Sync-RX, Ltd. Flow-related image processing in luminal organs
US8688212B2 (en) 2012-07-20 2014-04-01 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing bradycardia through vagus nerve stimulation
US9617507B2 (en) * 2012-10-24 2017-04-11 IonOptix LLC Apparatus and method for culturing cells and tissue
US9643008B2 (en) 2012-11-09 2017-05-09 Cyberonics, Inc. Implantable neurostimulator-implemented method for enhancing post-exercise recovery through vagus nerve stimulation
US9452290B2 (en) 2012-11-09 2016-09-27 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing tachyarrhythmia through vagus nerve stimulation
US8923964B2 (en) 2012-11-09 2014-12-30 Cyberonics, Inc. Implantable neurostimulator-implemented method for enhancing heart failure patient awakening through vagus nerve stimulation
US9888956B2 (en) 2013-01-22 2018-02-13 Angiodynamics, Inc. Integrated pump and generator device and method of use
US9643011B2 (en) 2013-03-14 2017-05-09 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing tachyarrhythmic risk during sleep through vagus nerve stimulation
CN105283123A (zh) * 2013-04-15 2016-01-27 T&W工程公司 带有植入式部件的ecg监测器
US9999773B2 (en) 2013-10-30 2018-06-19 Cyberonics, Inc. Implantable neurostimulator-implemented method utilizing multi-modal stimulation parameters
EP3077044B1 (en) 2013-12-05 2018-08-29 Cardiac Pacemakers, Inc. System for dosed delivery of autonomic modulation therapy
US9370659B2 (en) 2013-12-05 2016-06-21 Cardiac Pacemakers, Inc. Intuited delivery of autonomic modulation therapy
US9511228B2 (en) 2014-01-14 2016-12-06 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing hypertension through renal denervation and vagus nerve stimulation
CN105979868B (zh) 2014-02-06 2020-03-10 C·R·巴德股份有限公司 用于血管内装置的导向和放置的系统和方法
US9272143B2 (en) 2014-05-07 2016-03-01 Cyberonics, Inc. Responsive neurostimulation for the treatment of chronic cardiac dysfunction
US9409024B2 (en) 2014-03-25 2016-08-09 Cyberonics, Inc. Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction
US9950169B2 (en) 2014-04-25 2018-04-24 Cyberonics, Inc. Dynamic stimulation adjustment for identification of a neural fulcrum
US9713719B2 (en) 2014-04-17 2017-07-25 Cyberonics, Inc. Fine resolution identification of a neural fulcrum for the treatment of chronic cardiac dysfunction
US9415224B2 (en) 2014-04-25 2016-08-16 Cyberonics, Inc. Neurostimulation and recording of physiological response for the treatment of chronic cardiac dysfunction
CN112807074A (zh) 2014-05-12 2021-05-18 弗吉尼亚暨州立大学知识产权公司 电穿孔系统
WO2015179634A2 (en) 2014-05-22 2015-11-26 CARDIONOMIC, Inc. Catheter and catheter system for electrical neuromodulation
US9737716B2 (en) 2014-08-12 2017-08-22 Cyberonics, Inc. Vagus nerve and carotid baroreceptor stimulation system
US9770599B2 (en) 2014-08-12 2017-09-26 Cyberonics, Inc. Vagus nerve stimulation and subcutaneous defibrillation system
US9533153B2 (en) 2014-08-12 2017-01-03 Cyberonics, Inc. Neurostimulation titration process
US12114911B2 (en) 2014-08-28 2024-10-15 Angiodynamics, Inc. System and method for ablating a tissue site by electroporation with real-time pulse monitoring
AU2015315658B2 (en) 2014-09-08 2019-05-23 CARDIONOMIC, Inc. Catheter and electrode systems for electrical neuromodulation
WO2016040038A1 (en) 2014-09-08 2016-03-17 CARDIONOMIC, Inc. Methods for electrical neuromodulation of the heart
US9504832B2 (en) 2014-11-12 2016-11-29 Cyberonics, Inc. Neurostimulation titration process via adaptive parametric modification
WO2016100325A1 (en) 2014-12-15 2016-06-23 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
CN109568786A (zh) 2015-01-05 2019-04-05 卡迪诺米克公司 心脏调节促进方法及系统
US10973584B2 (en) 2015-01-19 2021-04-13 Bard Access Systems, Inc. Device and method for vascular access
US10327648B2 (en) 2015-04-01 2019-06-25 Siemens Healthcare Gmbh Blood vessel mechanical signal analysis
WO2016210325A1 (en) 2015-06-26 2016-12-29 C.R. Bard, Inc. Connector interface for ecg-based catheter positioning system
US11000207B2 (en) 2016-01-29 2021-05-11 C. R. Bard, Inc. Multiple coil system for tracking a medical device
SG11201807446UA (en) 2016-03-09 2018-09-27 Cardionomic Inc Cardiac contractility neurostimulation systems and methods
WO2017184753A1 (en) 2016-04-19 2017-10-26 Inspire Medical Systems, Inc. Accelerometer-based sensing for sleep disordered breathing (sdb) care
GB2550854B (en) 2016-05-25 2019-06-26 Ge Aviat Systems Ltd Aircraft time synchronization system
JP6622149B2 (ja) * 2016-06-28 2019-12-18 日本電信電話株式会社 ウェアラブルデバイス
CA3029899A1 (en) 2016-07-07 2018-01-11 The Regents Of The University Of California Implants using ultrasonic backscatter for detecting electrophysiological signals
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
WO2019055434A1 (en) 2017-09-13 2019-03-21 CARDIONOMIC, Inc. NEUROSTIMULATION SYSTEMS AND METHODS FOR AFFECTING CARDIAC CONTRACTILITY
WO2019075459A1 (en) 2017-10-13 2019-04-18 Mayo Foundation For Medical Education And Research ELECTROPORATION METHODS AND DEVICES FOR TREATING VENTRICULAR FIBRILLATION
CN111417431B (zh) 2017-11-29 2024-08-06 美敦力公司 使用斜变驱动信号进行的组织传导通信
CN111417434B (zh) 2017-11-29 2024-09-17 美敦力公司 用于减少来自组织传导通信发射的伪影的设备和方法
EP3717062B1 (en) 2017-11-29 2022-10-12 Medtronic, Inc. Tissue conduction communication between devices
WO2019108581A1 (en) 2017-11-29 2019-06-06 Medtronic, Inc. Signal transmission optimization for tissue conduction communication
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
EP3723845B1 (en) 2017-12-11 2025-01-22 Mayo Foundation for Medical Education and Research Systems for electroporation
US11229796B2 (en) 2017-12-15 2022-01-25 Medtronic Inc. Device, system and method with adaptive timing for tissue conduction communication transmission
KR101989402B1 (ko) * 2018-01-11 2019-06-14 서울대학교산학협력단 자율신경계 활동 유도 장치 및 그 방법
US12390262B2 (en) 2018-03-13 2025-08-19 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
WO2019222088A1 (en) * 2018-05-15 2019-11-21 Livanova Usa, Inc. Assessment system with wand detection cable synchronizing ecg recording
EP3793669A4 (en) 2018-05-15 2022-03-02 Livanova USA, Inc. R-R INTERVAL ANALYSIS FOR ECG WAVEFORMS TO ASSESS AUTONOMOUS RESPONSE TO NERVE VAGUE SIMULATION
WO2019222086A1 (en) 2018-05-15 2019-11-21 Livanova Usa, Inc. Poincare display to assess autonomic engagement responsive to vagus nerve stimulation
US11752341B2 (en) 2018-05-15 2023-09-12 Livanova Usa, Inc. Display signal to assess autonomic response to vagus nerve stimulation treatment
SG11202101191PA (en) 2018-08-13 2021-03-30 Cardionomic Inc Systems and methods for affecting cardiac contractility and/or relaxation
CN112867443B (zh) 2018-10-16 2024-04-26 巴德阿克塞斯系统股份有限公司 用于建立电连接的安全装备连接系统及其方法
US20200126391A1 (en) * 2018-10-22 2020-04-23 Nicole Lovett Drowning Prevention System
AU2020269601A1 (en) 2019-05-06 2021-12-02 CARDIONOMIC, Inc. Systems and methods for denoising physiological signals during electrical neuromodulation
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
US12214189B2 (en) 2019-07-24 2025-02-04 Virginia Tech Intellectual Properties, Inc. Fourier analysis spectroscopy for monitoring tissue impedance changes and treatment outcome during electroporation-based-therapies
EP4003497A1 (en) 2019-07-25 2022-06-01 Inspire Medical Systems, Inc. Systems and methods for operating an implantable medical device based upon sensed posture information
AU2020316105B2 (en) 2019-07-25 2025-07-31 Inspire Medical Systems, Inc. Respiration detection
WO2022006337A1 (en) * 2020-06-30 2022-01-06 Arrhythmia Dynamics Llc Systems and methods for diagnosing and treating fibrillation
US12485279B2 (en) 2020-11-25 2025-12-02 Virginia Tech Intellectual Properties, Inc. Methods for modulating temporal infrastructure of pulsed electric fields
JPWO2023132178A1 (enExample) * 2022-01-07 2023-07-13
US20230364413A1 (en) * 2022-05-13 2023-11-16 Electrocore, Inc. Systems and methods for optimizing nerve stimulation

Family Cites Families (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3421511A (en) * 1965-12-10 1969-01-14 Medtronic Inc Implantable electrode for nerve stimulation
SE346468B (enExample) * 1969-02-24 1972-07-10 Lkb Medical Ab
US5190035A (en) * 1981-06-18 1993-03-02 Cardiac Pacemakers, Inc. Biomedical method and apparatus for controlling the administration of therapy to a patient in response to changes in physiological demand
CA1215128A (en) 1982-12-08 1986-12-09 Pedro Molina-Negro Electric nerve stimulator device
DE3535504A1 (de) * 1985-10-04 1987-04-09 Siemens Ag Herzschrittmacher
US4759368A (en) * 1986-12-02 1988-07-26 Medical Designs, Inc. Transcutaneous nerve stimulator
US4791931A (en) * 1987-08-13 1988-12-20 Pacesetter Infusion, Ltd. Demand pacemaker using an artificial baroreceptor reflex
US4938223A (en) * 1988-03-28 1990-07-03 T. H. Charters, Inc. Transcutaneous nerve block device
US5111815A (en) * 1990-10-15 1992-05-12 Cardiac Pacemakers, Inc. Method and apparatus for cardioverter/pacer utilizing neurosensing
US5437285A (en) * 1991-02-20 1995-08-01 Georgetown University Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac electrical stability
US5188106A (en) * 1991-03-08 1993-02-23 Telectronics Pacing Systems, Inc. Method and apparatus for chronically monitoring the hemodynamic state of a patient using doppler ultrasound
US5199428A (en) * 1991-03-22 1993-04-06 Medtronic, Inc. Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload
US5318592A (en) * 1991-09-12 1994-06-07 BIOTRONIK, Mess- und Therapiegerate GmbH & Co., Ingenieurburo Berlin Cardiac therapy system
US5203326A (en) * 1991-12-18 1993-04-20 Telectronics Pacing Systems, Inc. Antiarrhythmia pacer using antiarrhythmia pacing and autonomic nerve stimulation therapy
US5330507A (en) * 1992-04-24 1994-07-19 Medtronic, Inc. Implantable electrical vagal stimulation for prevention or interruption of life threatening arrhythmias
US5243980A (en) * 1992-06-30 1993-09-14 Medtronic, Inc. Method and apparatus for discrimination of ventricular and supraventricular tachycardia
WO1994000190A1 (en) * 1992-06-30 1994-01-06 Medtronic, Inc. Method and apparatus for treatment of heart disorders
US5403351A (en) * 1993-01-11 1995-04-04 Saksena; Sanjeev Method of transvenous defibrillation/cardioversion employing an endocardial lead system
US5411531A (en) * 1993-09-23 1995-05-02 Medtronic, Inc. Method and apparatus for control of A-V interval
US5522854A (en) * 1994-05-19 1996-06-04 Duke University Method and apparatus for the prevention of arrhythmia by nerve stimulation
EP0688578B1 (en) * 1994-06-24 1999-11-10 Pacesetter AB Arrhythmia detector
EP0688579B1 (en) * 1994-06-24 2001-08-22 St. Jude Medical AB Device for heart therapy
US5556421A (en) * 1995-02-22 1996-09-17 Intermedics, Inc. Implantable medical device with enclosed physiological parameter sensors or telemetry link
US5700282A (en) * 1995-10-13 1997-12-23 Zabara; Jacob Heart rhythm stabilization using a neurocybernetic prosthesis
US6073048A (en) * 1995-11-17 2000-06-06 Medtronic, Inc. Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure
US6035233A (en) * 1995-12-11 2000-03-07 Intermedics Inc. Implantable medical device responsive to heart rate variability analysis
US5731848A (en) * 1995-12-22 1998-03-24 Samsung Electronics Co., Ltd. Digital VSB detector with bandpass phase tracker using Ng filters, as for use in an HDTV receiver
US5690681A (en) * 1996-03-29 1997-11-25 Purdue Research Foundation Method and apparatus using vagal stimulation for control of ventricular rate during atrial fibrillation
US6628987B1 (en) * 2000-09-26 2003-09-30 Medtronic, Inc. Method and system for sensing cardiac contractions during vagal stimulation-induced cardiopalegia
US6532388B1 (en) * 1996-04-30 2003-03-11 Medtronic, Inc. Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure
US6006134A (en) * 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US6449507B1 (en) * 1996-04-30 2002-09-10 Medtronic, Inc. Method and system for nerve stimulation prior to and during a medical procedure
US6076015A (en) * 1998-02-27 2000-06-13 Cardiac Pacemakers, Inc. Rate adaptive cardiac rhythm management device using transthoracic impedance
US6058331A (en) * 1998-04-27 2000-05-02 Medtronic, Inc. Apparatus and method for treating peripheral vascular disease and organ ischemia by electrical stimulation with closed loop feedback control
US5928272A (en) * 1998-05-02 1999-07-27 Cyberonics, Inc. Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity
EP1079893B1 (en) * 1998-05-08 2005-08-03 Cardiac Pacemakers, Inc. Cardiac pacing using adjustable atrio-ventricular delays
WO1999065561A1 (en) * 1998-06-19 1999-12-23 Cordis Webster, Inc. Method and apparatus for transvascular treatment of tachycardia and fibrillation
US20030212440A1 (en) * 2002-05-09 2003-11-13 Boveja Birinder R. Method and system for modulating the vagus nerve (10th cranial nerve) using modulated electrical pulses with an inductively coupled stimulation system
US6134470A (en) * 1998-11-09 2000-10-17 Medtronic, Inc. Method and apparatus for treating a tachyarrhythmic patient
US6181966B1 (en) * 1998-12-28 2001-01-30 Biotronik Mess- und Therapieger{umlaut over (a)}te GmbH & Co. Heart therapy apparatus with therapy correction means
DE69918657T2 (de) * 1999-01-28 2005-09-08 Sorin Biomedica Crm S.R.L., Saluggia Herzstimulationsgerät mit elektrotonischer Blockade
US6178349B1 (en) * 1999-04-15 2001-01-23 Medtronic, Inc. Drug delivery neural stimulation device for treatment of cardiovascular disorders
US6285909B1 (en) 1999-05-27 2001-09-04 Cardiac Pacemakers, Inc. Preserving patient specific data in implantable pulse generator systems
DE19929705A1 (de) * 1999-06-29 2001-01-04 Biotronik Mess & Therapieg Verfahren zur Bestimmung der Baroreflex-Latenzzeit und Baroreflex-Sensitivität
US6272377B1 (en) * 1999-10-01 2001-08-07 Cardiac Pacemakers, Inc. Cardiac rhythm management system with arrhythmia prediction and prevention
US6473644B1 (en) * 1999-10-13 2002-10-29 Cyberonics, Inc. Method to enhance cardiac capillary growth in heart failure patients
EP1106206B1 (de) * 1999-11-30 2007-06-27 BIOTRONIK GmbH & Co. KG Gerät zur Regelung der Herzfrequenz und der Herzpumpkraft
US6611713B2 (en) * 1999-11-30 2003-08-26 Patrick Schauerte Implantable device for diagnosing and distinguishing supraventricular and ventricular tachycardias
US6415183B1 (en) * 1999-12-09 2002-07-02 Cardiac Pacemakers, Inc. Method and apparatus for diaphragmatic pacing
FR2802433B1 (fr) * 1999-12-17 2002-05-17 Ela Medical Sa Dispositif medical, implantable actif, notamment stimulateur cardiaque, defibrillateur et/ou cardiovecteur du type multisite comportant des moyens de resynchronisation des ventricules
US6487450B1 (en) * 2000-02-24 2002-11-26 Cedars-Sinai Medical Center System and method for preventing Sudden Cardiac Death by nerve sprouting from right stellate ganglion
US6371922B1 (en) * 2000-04-07 2002-04-16 Cardiac Pacemakers, Inc. Method for measuring baroreflex sensitivity and therapy optimization in heart failure patients
US6511500B1 (en) * 2000-06-06 2003-01-28 Marc Mounir Rahme Use of autonomic nervous system neurotransmitters inhibition and atrial parasympathetic fibers ablation for the treatment of atrial arrhythmias and to preserve drug effects
US7831305B2 (en) 2001-10-15 2010-11-09 Advanced Neuromodulation Systems, Inc. Neural stimulation system and method responsive to collateral neural activity
US7623926B2 (en) 2000-09-27 2009-11-24 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US6850801B2 (en) * 2001-09-26 2005-02-01 Cvrx, Inc. Mapping methods for cardiovascular reflex control devices
US7840271B2 (en) 2000-09-27 2010-11-23 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US7499742B2 (en) * 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US6522926B1 (en) * 2000-09-27 2003-02-18 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US6985774B2 (en) 2000-09-27 2006-01-10 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US7158832B2 (en) * 2000-09-27 2007-01-02 Cvrx, Inc. Electrode designs and methods of use for cardiovascular reflex control devices
US6631290B1 (en) * 2000-10-25 2003-10-07 Medtronic, Inc. Multilayer ceramic electrodes for sensing cardiac depolarization signals
DE60139411D1 (de) * 2000-10-26 2009-09-10 Medtronic Inc Gerät zur minimierung der wirkungen einer herzverletzung
CA2426944A1 (en) * 2000-10-26 2002-05-02 Medtronic, Inc. Method and apparatus to minimize the effects of a cardiac insult
CA2426810A1 (en) * 2000-10-26 2002-06-13 Medtronic, Inc. Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions
US6904315B2 (en) * 2000-12-14 2005-06-07 Medtronic, Inc. Atrial aware VVI: a method for atrial synchronous ventricular (VDD/R) pacing using the subcutaneous electrode array and a standard pacing lead
US6399092B1 (en) 2000-12-27 2002-06-04 Healthpoint, Ltd. Anhydrous, hydrophilic absorbent wound dressing (tube) with antimicrobials or other pharmaceutically active agents
US6564096B2 (en) * 2001-02-28 2003-05-13 Robert A. Mest Method and system for treatment of tachycardia and fibrillation
WO2002085448A2 (en) * 2001-04-20 2002-10-31 The Board Of Regents Of The University Of Oklahoma Cardiac neuromodulation and methods of using same
JP2004533297A (ja) * 2001-05-29 2004-11-04 メドトロニック・インコーポレーテッド 心臓病の予防及び処置のための閉ループ神経調節システム
WO2002102239A2 (en) * 2001-06-19 2002-12-27 Mouse Specifics, Inc. Method of early detection of duchenne muscular dystrophy and other neuromuscular disease
US6622041B2 (en) 2001-08-21 2003-09-16 Cyberonics, Inc. Treatment of congestive heart failure and autonomic cardiovascular drive disorders
WO2003020364A2 (en) * 2001-08-28 2003-03-13 Medtronic, Inc. Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation
US7778703B2 (en) * 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
US7778711B2 (en) * 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US6934583B2 (en) * 2001-10-22 2005-08-23 Pacesetter, Inc. Implantable lead and method for stimulating the vagus nerve
US20030149450A1 (en) * 2002-02-01 2003-08-07 Mayberg Marc R. Brainstem and cerebellar modulation of cardiovascular response and disease
JP2005519680A (ja) 2002-03-14 2005-07-07 ブレインズゲート リミティド 血圧制御技術
US20030195571A1 (en) 2002-04-12 2003-10-16 Burnes John E. Method and apparatus for the treatment of central sleep apnea using biventricular pacing
US6882882B2 (en) * 2002-04-22 2005-04-19 Medtronic, Inc. Atrioventricular delay adjustment
US7123967B2 (en) * 2002-05-13 2006-10-17 Pacesetter, Inc. Implantable neural stimulation device providing activity, rest, and long term closed-loop peripheral vascular disease therapy and method
US7123961B1 (en) * 2002-06-13 2006-10-17 Pacesetter, Inc. Stimulation of autonomic nerves
US7027858B2 (en) * 2002-09-11 2006-04-11 Medtronic, Inc. Methods and apparatus for cardiac R-wave sensing in a subcutaneous ECG waveform
US7103418B2 (en) * 2002-10-02 2006-09-05 Medtronic, Inc. Active fluid delivery catheter
US20040088009A1 (en) * 2002-10-31 2004-05-06 Degroot Paul J. Auxilary central nervous system pre-pulse for shock pain inhibition
US20030229380A1 (en) 2002-10-31 2003-12-11 Adams John M. Heart failure therapy device and method
US7305265B2 (en) 2002-11-25 2007-12-04 Terumo Kabushiki Kaisha Heart treatment equipment for treating heart failure
US7142917B2 (en) 2002-12-04 2006-11-28 Terumo Kabushiki Kaisha Heart treatment equipment and method for preventing fatal arrhythmia
US7972275B2 (en) * 2002-12-30 2011-07-05 Cardiac Pacemakers, Inc. Method and apparatus for monitoring of diastolic hemodynamics
US7025730B2 (en) * 2003-01-10 2006-04-11 Medtronic, Inc. System and method for automatically monitoring and delivering therapy for sleep-related disordered breathing
US7088008B2 (en) * 2003-03-20 2006-08-08 International Business Machines Corporation Electronic package with optimized circuitization pattern
US7346393B2 (en) * 2003-06-12 2008-03-18 Cardiac Pacemakers, Inc. Implantable cardiac rhythm management system having multiple therapy modalities
US7092759B2 (en) * 2003-07-30 2006-08-15 Medtronic, Inc. Method of optimizing cardiac resynchronization therapy using sensor signals of septal wall motion
US20050055060A1 (en) * 2003-09-05 2005-03-10 Steve Koh Determination of respiratory characteristics from AV conduction intervals
EP1527930A3 (de) * 2003-10-29 2005-11-30 Alfred Engelmann Holding GmbH Vorrichtung zur Verriegelung und/oder Entriegelung einer Tanklappe
US7657312B2 (en) * 2003-11-03 2010-02-02 Cardiac Pacemakers, Inc. Multi-site ventricular pacing therapy with parasympathetic stimulation
US7783353B2 (en) 2003-12-24 2010-08-24 Cardiac Pacemakers, Inc. Automatic neural stimulation modulation based on activity and circadian rhythm
US20050149132A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US8126559B2 (en) * 2004-11-30 2012-02-28 Cardiac Pacemakers, Inc. Neural stimulation with avoidance of inappropriate stimulation
US20050149129A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Baropacing and cardiac pacing to control output
US7643875B2 (en) 2003-12-24 2010-01-05 Cardiac Pacemakers, Inc. Baroreflex stimulation system to reduce hypertension
US7431699B2 (en) * 2003-12-24 2008-10-07 Cardiac Pacemakers, Inc. Method and apparatus for third heart sound detection
US7869881B2 (en) * 2003-12-24 2011-01-11 Cardiac Pacemakers, Inc. Baroreflex stimulator with integrated pressure sensor
US7460906B2 (en) * 2003-12-24 2008-12-02 Cardiac Pacemakers, Inc. Baroreflex stimulation to treat acute myocardial infarction
US8396560B2 (en) * 2004-11-18 2013-03-12 Cardiac Pacemakers, Inc. System and method for closed-loop neural stimulation
US7509166B2 (en) * 2003-12-24 2009-03-24 Cardiac Pacemakers, Inc. Automatic baroreflex modulation responsive to adverse event
US7647114B2 (en) * 2003-12-24 2010-01-12 Cardiac Pacemakers, Inc. Baroreflex modulation based on monitored cardiovascular parameter
US7873413B2 (en) * 2006-07-24 2011-01-18 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US7769450B2 (en) * 2004-11-18 2010-08-03 Cardiac Pacemakers, Inc. Cardiac rhythm management device with neural sensor
US8126560B2 (en) * 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US7706884B2 (en) * 2003-12-24 2010-04-27 Cardiac Pacemakers, Inc. Baroreflex stimulation synchronized to circadian rhythm
US20050149133A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Sensing with compensation for neural stimulator
US7486991B2 (en) * 2003-12-24 2009-02-03 Cardiac Pacemakers, Inc. Baroreflex modulation to gradually decrease blood pressure
US8024050B2 (en) * 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US7299086B2 (en) * 2004-03-05 2007-11-20 Cardiac Pacemakers, Inc. Wireless ECG in implantable devices
US7260431B2 (en) * 2004-05-20 2007-08-21 Cardiac Pacemakers, Inc. Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device
US20060004417A1 (en) * 2004-06-30 2006-01-05 Cvrx, Inc. Baroreflex activation for arrhythmia treatment
US20060074453A1 (en) * 2004-10-04 2006-04-06 Cvrx, Inc. Baroreflex activation and cardiac resychronization for heart failure treatment
US8175705B2 (en) * 2004-10-12 2012-05-08 Cardiac Pacemakers, Inc. System and method for sustained baroreflex stimulation
US7655014B2 (en) * 2004-12-06 2010-02-02 Cameron Health, Inc. Apparatus and method for subcutaneous electrode insertion
US9089691B2 (en) 2004-12-07 2015-07-28 Cardiac Pacemakers, Inc. Stimulator for auricular branch of vagus nerve
US7587238B2 (en) * 2005-03-11 2009-09-08 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
US7660628B2 (en) * 2005-03-23 2010-02-09 Cardiac Pacemakers, Inc. System to provide myocardial and neural stimulation
US7542800B2 (en) 2005-04-05 2009-06-02 Cardiac Pacemakers, Inc. Method and apparatus for synchronizing neural stimulation to cardiac cycles
US8406876B2 (en) * 2005-04-05 2013-03-26 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US20060241725A1 (en) 2005-04-25 2006-10-26 Imad Libbus Method and apparatus for simultaneously presenting cardiac and neural signals
US7551958B2 (en) 2005-05-24 2009-06-23 Cardiac Pacemakers, Inc. Safety control system for implantable neural stimulator
US7570999B2 (en) * 2005-12-20 2009-08-04 Cardiac Pacemakers, Inc. Implantable device for treating epilepsy and cardiac rhythm disorders
US7801601B2 (en) 2006-01-27 2010-09-21 Cyberonics, Inc. Controlling neuromodulation using stimulus modalities
US20090018596A1 (en) * 2007-05-15 2009-01-15 Cvrx, Inc. Baroreflex activation therapy device with pacing cardiac electrical signal detection capability
WO2010011969A1 (en) * 2008-07-24 2010-01-28 Boston Scientific Neuromodulation Corporation System and method for avoiding, reversing, and managing neurological accomodation to electrical stimulation
US8084871B2 (en) * 2009-11-10 2011-12-27 Maxim Integrated Products, Inc. Redistribution layer enhancement to improve reliability of wafer level packaging

Also Published As

Publication number Publication date
US20060224188A1 (en) 2006-10-05
JP2013059633A (ja) 2013-04-04
EP1871464A1 (en) 2008-01-02
JP2008534218A (ja) 2008-08-28
US7542800B2 (en) 2009-06-02
US20090228060A1 (en) 2009-09-10
US20130253616A1 (en) 2013-09-26
EP1871464B1 (en) 2017-03-01
US8452398B2 (en) 2013-05-28
WO2006107675A1 (en) 2006-10-12

Similar Documents

Publication Publication Date Title
JP5174655B2 (ja) 心臓周期に同期化される神経刺激器
US9962548B2 (en) Closed loop neural stimulation synchronized to cardiac cycles
US7873413B2 (en) Closed loop neural stimulation synchronized to cardiac cycles
US20220409064A1 (en) Change in physiological parameter in response to exertion event
CN109310871B (zh) 对急性心脏病发作和发病的多参数预测
US9867987B2 (en) Remote detection of physiological parameter using an implantable medical device
US8862226B2 (en) Remote sensing in an implantable medical device
JP3959025B2 (ja) 平均肺動脈圧を決定する方法および装置
AU2010273546B2 (en) Physiological vibration detection in an implanted medical device
US7914452B2 (en) Method and apparatus for controlling cardiac therapy using ultrasound transducer
US8287459B2 (en) Interpolating left ventricular pressures
CN111417433A (zh) 从心室植入的无引线心脏起搏器检测心室充盈期间心房收缩定时基准的方法和系统
US7569020B2 (en) Method for extracting timing parameters using a cardio-mechanical sensor

Legal Events

Date Code Title Description
RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20090310

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20090310

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090325

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090325

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20090724

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20090724

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111031

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120131

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120312

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120608

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120705

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121105

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20121112

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20121213

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121228

R150 Certificate of patent or registration of utility model

Ref document number: 5174655

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D03

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees