JP5165239B2 - 制御放出処方物の調製のための方法 - Google Patents

制御放出処方物の調製のための方法 Download PDF

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Publication number
JP5165239B2
JP5165239B2 JP2006520347A JP2006520347A JP5165239B2 JP 5165239 B2 JP5165239 B2 JP 5165239B2 JP 2006520347 A JP2006520347 A JP 2006520347A JP 2006520347 A JP2006520347 A JP 2006520347A JP 5165239 B2 JP5165239 B2 JP 5165239B2
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group
organic
organic phase
microparticles
solvent
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Expired - Fee Related
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Japanese (ja)
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JP2007524645A5 (cg-RX-API-DMAC7.html
JP2007524645A (ja
Inventor
ピー． クック ガリー，
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ピーアール ファーマシューティカルズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006520347A 2003-07-15 2004-07-15 制御放出処方物の調製のための方法 Expired - Fee Related JP5165239B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48766303P 2003-07-15 2003-07-15
US60/487,663 2003-07-15
PCT/US2004/022816 WO2005009356A2 (en) 2003-07-15 2004-07-15 Method for the preparation of controlled release formulations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011100206A Division JP2011144207A (ja) 2003-07-15 2011-04-27 制御放出処方物の調製のための方法

Publications (3)

Publication Number Publication Date
JP2007524645A JP2007524645A (ja) 2007-08-30
JP2007524645A5 JP2007524645A5 (cg-RX-API-DMAC7.html) 2012-07-19
JP5165239B2 true JP5165239B2 (ja) 2013-03-21

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006520347A Expired - Fee Related JP5165239B2 (ja) 2003-07-15 2004-07-15 制御放出処方物の調製のための方法
JP2011100206A Pending JP2011144207A (ja) 2003-07-15 2011-04-27 制御放出処方物の調製のための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011100206A Pending JP2011144207A (ja) 2003-07-15 2011-04-27 制御放出処方物の調製のための方法

Country Status (9)

Country Link
US (1) US8871269B2 (cg-RX-API-DMAC7.html)
EP (2) EP1651136B1 (cg-RX-API-DMAC7.html)
JP (2) JP5165239B2 (cg-RX-API-DMAC7.html)
CN (2) CN1852687B (cg-RX-API-DMAC7.html)
AU (1) AU2004259208B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0412059A (cg-RX-API-DMAC7.html)
CA (1) CA2532302C (cg-RX-API-DMAC7.html)
ES (1) ES2625343T3 (cg-RX-API-DMAC7.html)
WO (1) WO2005009356A2 (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
US8871269B2 (en) 2014-10-28
EP1651136B1 (en) 2017-03-08
EP2462896A1 (en) 2012-06-13
US20060228414A1 (en) 2006-10-12
BRPI0412059A (pt) 2006-09-05
EP1651136A2 (en) 2006-05-03
JP2011144207A (ja) 2011-07-28
CN1852687A (zh) 2006-10-25
CN102935069A (zh) 2013-02-20
WO2005009356A2 (en) 2005-02-03
AU2004259208A1 (en) 2005-02-03
CN1852687B (zh) 2014-01-22
WO2005009356A3 (en) 2005-06-09
CA2532302A1 (en) 2005-02-03
ES2625343T3 (es) 2017-07-19
JP2007524645A (ja) 2007-08-30
EP1651136A4 (en) 2009-07-08
CA2532302C (en) 2016-12-20
AU2004259208B2 (en) 2011-04-28

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