JP5149618B2 - グルココルチコイド代償療法用の医薬組成物 - Google Patents

グルココルチコイド代償療法用の医薬組成物 Download PDF

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Publication number
JP5149618B2
JP5149618B2 JP2007508863A JP2007508863A JP5149618B2 JP 5149618 B2 JP5149618 B2 JP 5149618B2 JP 2007508863 A JP2007508863 A JP 2007508863A JP 2007508863 A JP2007508863 A JP 2007508863A JP 5149618 B2 JP5149618 B2 JP 5149618B2
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Japan
Prior art keywords
hydrocortisone
tablet
glucocorticoids
released
release
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP2007508863A
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English (en)
Japanese (ja)
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JP2007533698A (ja
JP2007533698A5 (enExample
Inventor
スクルティク，スタンコ
ヨンソン，ヨルゲン
レナーナス，ハンス
ヘドナー，トーマス
ヨハンソン，ガドマンダー
Original Assignee
デュオコート ファーマ エービー
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Publication of JP2007533698A publication Critical patent/JP2007533698A/ja
Publication of JP2007533698A5 publication Critical patent/JP2007533698A5/ja
Application granted granted Critical
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Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
JP2007508863A 2004-04-22 2005-04-21 グルココルチコイド代償療法用の医薬組成物 Expired - Lifetime JP5149618B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56420504P 2004-04-22 2004-04-22
SE0401031A SE0401031D0 (sv) 2004-04-22 2004-04-22 A new glucocorticoid replacement therapy
US60/564,205 2004-04-22
SE0401031-0 2004-04-22
PCT/EP2005/004400 WO2005102271A2 (en) 2004-04-22 2005-04-21 Pharmaceutical compositions for glucocorticoid replacement therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012173158A Division JP5681679B2 (ja) 2004-04-22 2012-08-03 グルココルチコイド代償療法用の医薬組成物

Publications (3)

Publication Number Publication Date
JP2007533698A JP2007533698A (ja) 2007-11-22
JP2007533698A5 JP2007533698A5 (enExample) 2012-03-22
JP5149618B2 true JP5149618B2 (ja) 2013-02-20

Family

ID=35197481

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007508863A Expired - Lifetime JP5149618B2 (ja) 2004-04-22 2005-04-21 グルココルチコイド代償療法用の医薬組成物
JP2012173158A Expired - Lifetime JP5681679B2 (ja) 2004-04-22 2012-08-03 グルココルチコイド代償療法用の医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012173158A Expired - Lifetime JP5681679B2 (ja) 2004-04-22 2012-08-03 グルココルチコイド代償療法用の医薬組成物

Country Status (25)

Country Link
US (3) US8425937B2 (enExample)
EP (2) EP1744730B1 (enExample)
JP (2) JP5149618B2 (enExample)
CN (2) CN1942176B (enExample)
AU (1) AU2005235370B2 (enExample)
BR (1) BRPI0510044B8 (enExample)
CA (1) CA2564000C (enExample)
CY (2) CY1118275T1 (enExample)
DK (2) DK3072507T3 (enExample)
ES (2) ES2600556T3 (enExample)
HR (2) HRP20161380T1 (enExample)
HU (2) HUE030546T2 (enExample)
IL (2) IL178776A (enExample)
LT (2) LT3072507T (enExample)
ME (1) ME02584B (enExample)
MX (2) MXPA06012011A (enExample)
NZ (1) NZ585340A (enExample)
PL (2) PL3072507T3 (enExample)
PT (2) PT3072507T (enExample)
RS (2) RS61501B1 (enExample)
SE (1) SE0401031D0 (enExample)
SG (1) SG188081A1 (enExample)
SI (1) SI3072507T1 (enExample)
WO (1) WO2005102271A2 (enExample)
ZA (1) ZA200609680B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0401031D0 (sv) * 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
PL1744760T3 (pl) * 2004-04-22 2015-04-30 Acucort Ab Kompozycja farmaceutyczna do ostrego leczenia glikokortykosteroidami
EP1971312A1 (en) * 2005-12-06 2008-09-24 MonoSol Rx LLC Topical film compositions for delivery of actives
FR2926722B1 (fr) * 2008-01-25 2010-09-03 Substipharm Dev Formulation pharmaceutique appropriee pour la preparation de comprimes orodispersibles de prednisolone
EP2151235B1 (de) * 2008-07-21 2011-02-16 Dr. Falk Pharma Gmbh Pharmazeutische Formulierung zur Behandlung des oberen Verdauungstraktes
US20120183610A1 (en) * 2009-04-07 2012-07-19 Lennernaes Hans glucocorticoid therapy
MX337429B (es) * 2010-05-20 2016-03-04 Duocort Pharma Ab Posologia y administracion de composiciones basadas en glucocortticoides.
GB201119985D0 (en) 2011-11-19 2012-01-04 Diurnal Ltd Treatment of adrenal insufficiency
GB201202433D0 (en) * 2012-02-13 2012-03-28 Diurnal Ltd Controlled drug release
JP2014086673A (ja) 2012-10-26 2014-05-12 Mitsubishi Electric Corp モノリシック集積回路
HUE056810T2 (hu) 2012-11-02 2022-03-28 Murray & Poole Entpr Ltd Szív- és érrendszeri események kezelése és megelõzése kolchicin alkalmazásával
HRP20210963T1 (hr) * 2013-04-16 2021-09-17 Murray & Poole Enterprises, Ltd. Formulacija za kontinuirano otpuštanje kolhicina i postupci priprave istog
BR112015026418B1 (pt) 2013-04-16 2022-10-04 Murray And Poole Enterprises Limited Formulação de liberação prolongada de colchicina e uso da referida formulação de liberação prolongada de colchicina
GB201308933D0 (en) * 2013-05-17 2013-07-03 Diurnal Ltd Paediatric composition
MX348595B (es) * 2013-08-02 2017-06-21 Laboratorio Raam De Sahuayo S A De C V Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion.
EP2886108B2 (de) 2013-12-23 2022-11-02 Dr. Falk Pharma Gmbh Optimierte pharmazeutische Formulierung zur Behandlung von entzündlichen Veränderungen des Ösophagus
ES2906778T3 (es) * 2015-03-30 2022-04-20 Corcept Therapeutics Inc Uso de antagonistas del receptor de glucocorticoides en combinación con glucocorticoides para tratar la insuficiencia suprarrenal
CN107115308B (zh) * 2016-02-23 2021-02-23 天津金耀集团有限公司 一种氢化可的松双相缓释片剂组合物
RU2748437C2 (ru) * 2019-10-28 2021-05-25 Федеральное государственное бюджетное учреждение науки Институт цитологии Российской академии наук (ИНЦ РАН) Производное гидрокортизона в качестве средства для лечения болезни Альцгеймера
FR3116439B1 (fr) * 2020-11-26 2023-08-04 Laboratoire Dielen Comprimé pelliculé contenant au moins un principe actif, adapté à l’administration par voie orale dudit au moins un principe actif chez des sujets humains

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DE2260384C3 (de) * 1972-12-09 1979-11-29 Hoechst Ag, 6000 Frankfurt Oral zu applizierendes Corticosteroid-Präparat
US5316772A (en) * 1990-12-19 1994-05-31 Solvay & Cie, S.A. (Societe Anonyme) Bilayered oral pharmaceutical composition with pH dependent release
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5314697A (en) 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
PT745382E (pt) * 1994-01-31 2004-04-30 Yamanouchi Pharma Co Ltd Forma moldada por compressao com solubilidade intra-oral e processo para a sua producao
US5534263A (en) 1995-02-24 1996-07-09 Alza Corporation Active agent dosage form comprising a matrix and at least two insoluble bands
US5976573A (en) 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
DE19718012C1 (de) * 1997-04-29 1998-10-08 Jenapharm Gmbh Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe
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AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
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GB0400031D0 (en) 2004-01-03 2004-02-04 Univ Sheffield Depression treatment
PL1744760T3 (pl) 2004-04-22 2015-04-30 Acucort Ab Kompozycja farmaceutyczna do ostrego leczenia glikokortykosteroidami
SE0401031D0 (sv) * 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
GB0623740D0 (en) 2006-11-28 2007-01-10 Diurnal Ltd Treatment of disease
US20120183610A1 (en) 2009-04-07 2012-07-19 Lennernaes Hans glucocorticoid therapy
MX337429B (es) 2010-05-20 2016-03-04 Duocort Pharma Ab Posologia y administracion de composiciones basadas en glucocortticoides.

Also Published As

Publication number Publication date
MXPA06012011A (es) 2007-04-16
AU2005235370B2 (en) 2011-06-09
US20080187586A1 (en) 2008-08-07
EP1744730A2 (en) 2007-01-24
JP5681679B2 (ja) 2015-03-11
BRPI0510044A (pt) 2007-10-16
JP2007533698A (ja) 2007-11-22
ES2857600T3 (es) 2021-09-29
WO2005102271A2 (en) 2005-11-03
SG188081A1 (en) 2013-03-28
US8425937B2 (en) 2013-04-23
MX344197B (es) 2016-12-08
AU2005235370A1 (en) 2005-11-03
CY1118275T1 (el) 2017-06-28
CN103006592B (zh) 2016-03-02
ME02584B (me) 2017-06-20
JP2012236846A (ja) 2012-12-06
HRP20210348T1 (hr) 2021-04-16
IL227375A (en) 2017-08-31
BRPI0510044B1 (pt) 2019-01-29
HRP20161380T1 (hr) 2016-12-02
IL178776A0 (en) 2007-02-11
DK3072507T3 (da) 2021-02-08
HK1179525A1 (zh) 2013-10-04
BRPI0510044B8 (pt) 2021-05-25
HUE053248T2 (hu) 2021-06-28
EP3072507A1 (en) 2016-09-28
WO2005102271A3 (en) 2006-08-03
CN103006592A (zh) 2013-04-03
CY1124074T1 (el) 2022-03-24
PT3072507T (pt) 2021-02-23
HUE030546T2 (en) 2017-05-29
EP3072507B1 (en) 2020-12-23
PL1744730T3 (pl) 2017-01-31
PT1744730T (pt) 2016-10-07
LT3072507T (lt) 2021-02-25
EP1744730B1 (en) 2016-08-03
ZA200609680B (en) 2008-08-27
NZ585340A (en) 2012-04-27
RS61501B1 (sr) 2021-03-31
CN1942176A (zh) 2007-04-04
US10583146B2 (en) 2020-03-10
RS55198B1 (sr) 2017-01-31
CA2564000A1 (en) 2005-11-03
SI3072507T1 (sl) 2021-04-30
DK1744730T3 (en) 2016-08-29
CA2564000C (en) 2013-07-02
CN1942176B (zh) 2013-09-18
US20140242167A1 (en) 2014-08-28
LT1744730T (lt) 2016-10-25
US20130129823A1 (en) 2013-05-23
IL178776A (en) 2013-10-31
PL3072507T3 (pl) 2021-07-19
ES2600556T3 (es) 2017-02-09
SE0401031D0 (sv) 2004-04-22

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