JP5149313B2 - 細胞増殖装置と共に使用するためのディスポーザブル配管セット、および無菌サンプリング方法 - Google Patents

細胞増殖装置と共に使用するためのディスポーザブル配管セット、および無菌サンプリング方法 Download PDF

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JP5149313B2
JP5149313B2 JP2009551768A JP2009551768A JP5149313B2 JP 5149313 B2 JP5149313 B2 JP 5149313B2 JP 2009551768 A JP2009551768 A JP 2009551768A JP 2009551768 A JP2009551768 A JP 2009551768A JP 5149313 B2 JP5149313 B2 JP 5149313B2
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cell growth
area
sample
fluid
growth area
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JP2010519903A (ja
JP2010519903A5 (cg-RX-API-DMAC7.html
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アントウィラー、グレン・デルバート
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Terumo BCT Inc
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Terumo BCT Inc
Gambro BCT Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/26—Inoculator or sampler
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/48—Holding appliances; Racks; Supports
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2009551768A 2007-03-01 2008-01-28 細胞増殖装置と共に使用するためのディスポーザブル配管セット、および無菌サンプリング方法 Expired - Fee Related JP5149313B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89246007P 2007-03-01 2007-03-01
US60/892,460 2007-03-01
US97138207P 2007-09-11 2007-09-11
US60/971,382 2007-09-11
PCT/US2008/052185 WO2008109200A1 (en) 2007-03-01 2008-01-28 Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling

Publications (3)

Publication Number Publication Date
JP2010519903A JP2010519903A (ja) 2010-06-10
JP2010519903A5 JP2010519903A5 (cg-RX-API-DMAC7.html) 2011-03-17
JP5149313B2 true JP5149313B2 (ja) 2013-02-20

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JP2009551768A Expired - Fee Related JP5149313B2 (ja) 2007-03-01 2008-01-28 細胞増殖装置と共に使用するためのディスポーザブル配管セット、および無菌サンプリング方法

Country Status (8)

Country Link
US (2) US7718430B2 (cg-RX-API-DMAC7.html)
EP (1) EP2115117A1 (cg-RX-API-DMAC7.html)
JP (1) JP5149313B2 (cg-RX-API-DMAC7.html)
KR (1) KR101440171B1 (cg-RX-API-DMAC7.html)
CN (1) CN101622337B (cg-RX-API-DMAC7.html)
AU (1) AU2008223280B2 (cg-RX-API-DMAC7.html)
CA (1) CA2679097C (cg-RX-API-DMAC7.html)
WO (1) WO2008109200A1 (cg-RX-API-DMAC7.html)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101622337B (zh) * 2007-03-01 2013-04-24 泰尔茂比司特公司 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法
CA2678893C (en) * 2007-03-05 2015-12-29 Caridianbct, Inc. Methods to control cell movement in hollow fiber bioreactors
EP2129764B1 (en) * 2007-03-05 2018-10-10 Terumo BCT, Inc. Cell expansion system and methods of use
US9284523B2 (en) 2008-10-27 2016-03-15 Terumo Bct, Inc. Premounted fluid conveyance assembly for cell expansion system and method of use associated therewith
US8999046B2 (en) 2008-10-27 2015-04-07 Terumo Bct, Inc. Air removal chamber for a cell expansion system and method of use associated therewith
US8399245B2 (en) 2009-02-18 2013-03-19 Terumo Bct, Inc. Rotation system for cell growth chamber of a cell expansion system and method of use therefor
AU2010232389A1 (en) * 2009-04-03 2011-10-20 Humacyte, Inc. Tissue and organ graft bioreactor and method of operation
GB0906836D0 (en) * 2009-04-21 2009-06-03 Cymtox Ltd Consumable component kit
WO2011090605A2 (en) * 2009-12-29 2011-07-28 Caridianbct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
WO2012044837A2 (en) * 2010-10-01 2012-04-05 Zevex, Inc. Method for improving accuracy in a peristaltic pump system based on tubing material properties
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
DK2718416T3 (da) 2011-06-06 2020-02-24 ReGenesys BVBA Ekspansion af stamceller i hulfiberbioreaktorer
DE102012200938B4 (de) 2012-01-23 2016-08-18 Alpha Plan Gmbh Bio- und medizintechnisches Baukastensystem
EP2885393A1 (en) * 2012-08-20 2015-06-24 Terumo BCT, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
JP2015526094A (ja) * 2012-08-20 2015-09-10 テルモ ビーシーティー、インコーポレーテッド 細胞成長チャンバーを循環する流体の成分を濃縮する方法
JP6633522B2 (ja) 2013-11-16 2020-01-22 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
CN106232800B (zh) 2014-03-25 2020-07-03 泰尔茂比司特公司 介质的被动替代
WO2015164808A1 (en) 2014-04-24 2015-10-29 Terumo Bct, Inc. Measuring flow rate
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN105087380A (zh) * 2015-07-31 2015-11-25 南方医科大学珠江医院 大规模培养动物细胞的系统
GB201600315D0 (en) 2015-08-13 2016-02-24 Gen Electric Heatseal sampling
EP3464565A4 (en) 2016-05-25 2020-01-01 Terumo BCT, Inc. CELL EXPANSION
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US20180057784A1 (en) 2016-08-27 2018-03-01 3D Biotek, Llc Bioreactor
EP3565883A1 (en) * 2017-02-10 2019-11-13 Lonza Ltd Cell culture system and method
EP3656842A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US10696961B2 (en) 2017-12-01 2020-06-30 Global Life Sciences Solutions Usa Llc Magnetic cell isolation techniques
US11371007B2 (en) 2018-02-09 2022-06-28 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US12252682B2 (en) 2018-02-09 2025-03-18 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US11932842B2 (en) 2018-02-09 2024-03-19 Global Life Sciences Solutions Usa Llc Bioprocessing apparatus
US11414639B2 (en) 2018-02-09 2022-08-16 Global Life Sciences Solutions Usa Llc Bioprocessing vessel
KR102694744B1 (ko) * 2018-02-09 2024-08-14 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 바이오프로세싱 용기
US11920119B2 (en) 2018-02-09 2024-03-05 Global Life Sciences Solutions Usa Llc Systems and methods for bioprocessing
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
US12077743B2 (en) 2018-02-09 2024-09-03 Global Life Sciences Solutions Usa Llc Apparatus for fluid line management in a bioprocessing system
JP7225796B2 (ja) * 2018-12-27 2023-02-21 大日本印刷株式会社 サンプリング機能付き容器
JP7638277B2 (ja) * 2020-02-06 2025-03-03 テルモ株式会社 流路カセット、細胞培養キット及び細胞培養システム
GB202017182D0 (en) * 2020-10-29 2020-12-16 Cytiva Sweden Ab Fluid coupling network for sampling a bioreactor
WO2023122133A1 (en) * 2021-12-22 2023-06-29 Pbs Biotech, Inc. Apparatus and methods for treating media in large-scale bioreactors
US12458740B2 (en) 2022-03-10 2025-11-04 Terumo Bct, Inc. Modular serviceability sleds and interconnections
US12379916B2 (en) 2022-03-10 2025-08-05 Terumo Bct, Inc. Communications and operation control of apheresis systems
US12478551B2 (en) 2022-03-10 2025-11-25 Terumo Bct, Inc. Collection bottle with integrated cap, handle, and shield features
US20250304901A1 (en) * 2024-03-26 2025-10-02 Waters Technologies Corporation Pneumatic transfer of fluid samples over lengthy conduits

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889812A (en) * 1986-05-12 1989-12-26 C. D. Medical, Inc. Bioreactor apparatus
JPH0576582A (ja) * 1991-09-20 1993-03-30 Hitachi Ltd マイクロ波滅菌方法、その滅菌装置及び培養システム
EP1325110A4 (en) * 2000-10-02 2009-03-25 Thomas F Cannon AUTOMATED BIOCULTURE AND BIOCULTURAL EXPERIENCE SYSTEM
US7198940B2 (en) * 2000-10-25 2007-04-03 Shot Hardware Optimization Technology, Inc. Bioreactor apparatus and cell culturing system
WO2002087491A1 (en) * 2001-04-27 2002-11-07 Baxter International Inc. Sealing apparatus and method
ATE522237T1 (de) * 2001-12-10 2011-09-15 Caridianbct Inc Verfahren zur verminderung des gehalts an leukozyten in einer komponente aus roten blutkörperchen
US8492140B2 (en) * 2002-04-08 2013-07-23 Octane Biotech Inc. Automated tissue engineering system
AU2003231286A1 (en) * 2002-05-03 2003-11-17 Gambro, Inc. Apparatus and method for detecting bacteria in blood products
JP4668568B2 (ja) * 2003-08-26 2011-04-13 株式会社メディネット 培養容器、培養装置および細胞の培養方法
EP1786894A4 (en) * 2004-09-10 2007-12-12 Unisearch Ltd DEVICE AND METHOD FOR PREVENTING CULTURE MEDIA REMOVAL
AU2006246263A1 (en) * 2005-05-09 2006-11-16 Saxonia Biotec Gmbh. Apparatus for providing media to cell culture modules
CN101622337B (zh) 2007-03-01 2013-04-24 泰尔茂比司特公司 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法

Also Published As

Publication number Publication date
US8163555B2 (en) 2012-04-24
KR101440171B1 (ko) 2014-09-15
US20100144037A1 (en) 2010-06-10
US20080213894A1 (en) 2008-09-04
AU2008223280B2 (en) 2013-09-19
KR20090121372A (ko) 2009-11-25
CA2679097A1 (en) 2008-09-12
JP2010519903A (ja) 2010-06-10
AU2008223280A1 (en) 2008-09-12
CA2679097C (en) 2015-04-28
EP2115117A1 (en) 2009-11-11
CN101622337A (zh) 2010-01-06
US7718430B2 (en) 2010-05-18
CN101622337B (zh) 2013-04-24
WO2008109200A1 (en) 2008-09-12

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