CA2679097C - Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling - Google Patents
Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling Download PDFInfo
- Publication number
- CA2679097C CA2679097C CA 2679097 CA2679097A CA2679097C CA 2679097 C CA2679097 C CA 2679097C CA 2679097 CA2679097 CA 2679097 CA 2679097 A CA2679097 A CA 2679097A CA 2679097 C CA2679097 C CA 2679097C
- Authority
- CA
- Canada
- Prior art keywords
- cellular
- area
- tube
- cellular growth
- growth area
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000010261 cell growth Effects 0.000 title claims abstract description 82
- 238000000034 method Methods 0.000 title claims description 16
- 238000005070 sampling Methods 0.000 title claims description 6
- 239000012530 fluid Substances 0.000 claims abstract description 61
- 230000001413 cellular effect Effects 0.000 claims abstract description 32
- 239000012528 membrane Substances 0.000 claims abstract description 19
- 238000004891 communication Methods 0.000 claims abstract description 16
- 150000001875 compounds Chemical class 0.000 claims description 12
- 238000013508 migration Methods 0.000 claims description 12
- 230000005012 migration Effects 0.000 claims description 12
- 238000007789 sealing Methods 0.000 claims description 6
- 210000004027 cell Anatomy 0.000 description 33
- 239000012510 hollow fiber Substances 0.000 description 14
- 239000007789 gas Substances 0.000 description 8
- 239000000835 fiber Substances 0.000 description 6
- 239000002699 waste material Substances 0.000 description 6
- 238000011072 cell harvest Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 210000000130 stem cell Anatomy 0.000 description 4
- 239000004812 Fluorinated ethylene propylene Substances 0.000 description 3
- 238000002617 apheresis Methods 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000000306 component Substances 0.000 description 3
- 239000002874 hemostatic agent Substances 0.000 description 3
- 230000002503 metabolic effect Effects 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229920009441 perflouroethylene propylene Polymers 0.000 description 3
- 230000002572 peristaltic effect Effects 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 229920000915 polyvinyl chloride Polymers 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 244000000022 airborne pathogen Species 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- HGAZMNJKRQFZKS-UHFFFAOYSA-N chloroethene;ethenyl acetate Chemical compound ClC=C.CC(=O)OC=C HGAZMNJKRQFZKS-UHFFFAOYSA-N 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 239000012737 fresh medium Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229920000110 poly(aryl ether sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/26—Inoculator or sampler
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89246007P | 2007-03-01 | 2007-03-01 | |
| US60/892,460 | 2007-03-01 | ||
| US97138207P | 2007-09-11 | 2007-09-11 | |
| US60/971,382 | 2007-09-11 | ||
| PCT/US2008/052185 WO2008109200A1 (en) | 2007-03-01 | 2008-01-28 | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2679097A1 CA2679097A1 (en) | 2008-09-12 |
| CA2679097C true CA2679097C (en) | 2015-04-28 |
Family
ID=39522125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2679097 Expired - Fee Related CA2679097C (en) | 2007-03-01 | 2008-01-28 | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7718430B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2115117A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5149313B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101440171B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101622337B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008223280B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2679097C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008109200A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101622337B (zh) * | 2007-03-01 | 2013-04-24 | 泰尔茂比司特公司 | 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法 |
| CA2678893C (en) * | 2007-03-05 | 2015-12-29 | Caridianbct, Inc. | Methods to control cell movement in hollow fiber bioreactors |
| EP2129764B1 (en) * | 2007-03-05 | 2018-10-10 | Terumo BCT, Inc. | Cell expansion system and methods of use |
| US9284523B2 (en) | 2008-10-27 | 2016-03-15 | Terumo Bct, Inc. | Premounted fluid conveyance assembly for cell expansion system and method of use associated therewith |
| US8999046B2 (en) | 2008-10-27 | 2015-04-07 | Terumo Bct, Inc. | Air removal chamber for a cell expansion system and method of use associated therewith |
| US8399245B2 (en) | 2009-02-18 | 2013-03-19 | Terumo Bct, Inc. | Rotation system for cell growth chamber of a cell expansion system and method of use therefor |
| AU2010232389A1 (en) * | 2009-04-03 | 2011-10-20 | Humacyte, Inc. | Tissue and organ graft bioreactor and method of operation |
| GB0906836D0 (en) * | 2009-04-21 | 2009-06-03 | Cymtox Ltd | Consumable component kit |
| WO2011090605A2 (en) * | 2009-12-29 | 2011-07-28 | Caridianbct, Inc. | Method of loading and distributing cells in a bioreactor of a cell expansion system |
| WO2012044837A2 (en) * | 2010-10-01 | 2012-04-05 | Zevex, Inc. | Method for improving accuracy in a peristaltic pump system based on tubing material properties |
| US8895291B2 (en) | 2010-10-08 | 2014-11-25 | Terumo Bct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
| DK2718416T3 (da) | 2011-06-06 | 2020-02-24 | ReGenesys BVBA | Ekspansion af stamceller i hulfiberbioreaktorer |
| DE102012200938B4 (de) | 2012-01-23 | 2016-08-18 | Alpha Plan Gmbh | Bio- und medizintechnisches Baukastensystem |
| EP2885393A1 (en) * | 2012-08-20 | 2015-06-24 | Terumo BCT, Inc. | Method of loading and distributing cells in a bioreactor of a cell expansion system |
| JP2015526094A (ja) * | 2012-08-20 | 2015-09-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞成長チャンバーを循環する流体の成分を濃縮する方法 |
| JP6633522B2 (ja) | 2013-11-16 | 2020-01-22 | テルモ ビーシーティー、インコーポレーテッド | バイオリアクターにおける細胞増殖 |
| CN106232800B (zh) | 2014-03-25 | 2020-07-03 | 泰尔茂比司特公司 | 介质的被动替代 |
| WO2015164808A1 (en) | 2014-04-24 | 2015-10-29 | Terumo Bct, Inc. | Measuring flow rate |
| JP6830059B2 (ja) | 2014-09-26 | 2021-02-17 | テルモ ビーシーティー、インコーポレーテッド | スケジュール化された細胞フィーディング |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CN105087380A (zh) * | 2015-07-31 | 2015-11-25 | 南方医科大学珠江医院 | 大规模培养动物细胞的系统 |
| GB201600315D0 (en) | 2015-08-13 | 2016-02-24 | Gen Electric | Heatseal sampling |
| EP3464565A4 (en) | 2016-05-25 | 2020-01-01 | Terumo BCT, Inc. | CELL EXPANSION |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US20180057784A1 (en) | 2016-08-27 | 2018-03-01 | 3D Biotek, Llc | Bioreactor |
| EP3565883A1 (en) * | 2017-02-10 | 2019-11-13 | Lonza Ltd | Cell culture system and method |
| EP3656842A1 (en) | 2017-03-31 | 2020-05-27 | Terumo BCT, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| US10696961B2 (en) | 2017-12-01 | 2020-06-30 | Global Life Sciences Solutions Usa Llc | Magnetic cell isolation techniques |
| US11371007B2 (en) | 2018-02-09 | 2022-06-28 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US12252682B2 (en) | 2018-02-09 | 2025-03-18 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US11932842B2 (en) | 2018-02-09 | 2024-03-19 | Global Life Sciences Solutions Usa Llc | Bioprocessing apparatus |
| US11414639B2 (en) | 2018-02-09 | 2022-08-16 | Global Life Sciences Solutions Usa Llc | Bioprocessing vessel |
| KR102694744B1 (ko) * | 2018-02-09 | 2024-08-14 | 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 | 바이오프로세싱 용기 |
| US11920119B2 (en) | 2018-02-09 | 2024-03-05 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
| US10889792B2 (en) | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| US12077743B2 (en) | 2018-02-09 | 2024-09-03 | Global Life Sciences Solutions Usa Llc | Apparatus for fluid line management in a bioprocessing system |
| JP7225796B2 (ja) * | 2018-12-27 | 2023-02-21 | 大日本印刷株式会社 | サンプリング機能付き容器 |
| JP7638277B2 (ja) * | 2020-02-06 | 2025-03-03 | テルモ株式会社 | 流路カセット、細胞培養キット及び細胞培養システム |
| GB202017182D0 (en) * | 2020-10-29 | 2020-12-16 | Cytiva Sweden Ab | Fluid coupling network for sampling a bioreactor |
| WO2023122133A1 (en) * | 2021-12-22 | 2023-06-29 | Pbs Biotech, Inc. | Apparatus and methods for treating media in large-scale bioreactors |
| US12458740B2 (en) | 2022-03-10 | 2025-11-04 | Terumo Bct, Inc. | Modular serviceability sleds and interconnections |
| US12379916B2 (en) | 2022-03-10 | 2025-08-05 | Terumo Bct, Inc. | Communications and operation control of apheresis systems |
| US12478551B2 (en) | 2022-03-10 | 2025-11-25 | Terumo Bct, Inc. | Collection bottle with integrated cap, handle, and shield features |
| US20250304901A1 (en) * | 2024-03-26 | 2025-10-02 | Waters Technologies Corporation | Pneumatic transfer of fluid samples over lengthy conduits |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889812A (en) * | 1986-05-12 | 1989-12-26 | C. D. Medical, Inc. | Bioreactor apparatus |
| JPH0576582A (ja) * | 1991-09-20 | 1993-03-30 | Hitachi Ltd | マイクロ波滅菌方法、その滅菌装置及び培養システム |
| EP1325110A4 (en) * | 2000-10-02 | 2009-03-25 | Thomas F Cannon | AUTOMATED BIOCULTURE AND BIOCULTURAL EXPERIENCE SYSTEM |
| US7198940B2 (en) * | 2000-10-25 | 2007-04-03 | Shot Hardware Optimization Technology, Inc. | Bioreactor apparatus and cell culturing system |
| WO2002087491A1 (en) * | 2001-04-27 | 2002-11-07 | Baxter International Inc. | Sealing apparatus and method |
| ATE522237T1 (de) * | 2001-12-10 | 2011-09-15 | Caridianbct Inc | Verfahren zur verminderung des gehalts an leukozyten in einer komponente aus roten blutkörperchen |
| US8492140B2 (en) * | 2002-04-08 | 2013-07-23 | Octane Biotech Inc. | Automated tissue engineering system |
| AU2003231286A1 (en) * | 2002-05-03 | 2003-11-17 | Gambro, Inc. | Apparatus and method for detecting bacteria in blood products |
| JP4668568B2 (ja) * | 2003-08-26 | 2011-04-13 | 株式会社メディネット | 培養容器、培養装置および細胞の培養方法 |
| EP1786894A4 (en) * | 2004-09-10 | 2007-12-12 | Unisearch Ltd | DEVICE AND METHOD FOR PREVENTING CULTURE MEDIA REMOVAL |
| AU2006246263A1 (en) * | 2005-05-09 | 2006-11-16 | Saxonia Biotec Gmbh. | Apparatus for providing media to cell culture modules |
| CN101622337B (zh) | 2007-03-01 | 2013-04-24 | 泰尔茂比司特公司 | 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法 |
-
2008
- 2008-01-28 CN CN2008800067945A patent/CN101622337B/zh not_active Expired - Fee Related
- 2008-01-28 CA CA 2679097 patent/CA2679097C/en not_active Expired - Fee Related
- 2008-01-28 EP EP08728380A patent/EP2115117A1/en not_active Withdrawn
- 2008-01-28 JP JP2009551768A patent/JP5149313B2/ja not_active Expired - Fee Related
- 2008-01-28 US US12/021,013 patent/US7718430B2/en not_active Expired - Fee Related
- 2008-01-28 KR KR1020097020706A patent/KR101440171B1/ko not_active Expired - Fee Related
- 2008-01-28 AU AU2008223280A patent/AU2008223280B2/en not_active Ceased
- 2008-01-28 WO PCT/US2008/052185 patent/WO2008109200A1/en not_active Ceased
-
2010
- 2010-02-16 US US12/706,380 patent/US8163555B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8163555B2 (en) | 2012-04-24 |
| KR101440171B1 (ko) | 2014-09-15 |
| US20100144037A1 (en) | 2010-06-10 |
| US20080213894A1 (en) | 2008-09-04 |
| AU2008223280B2 (en) | 2013-09-19 |
| KR20090121372A (ko) | 2009-11-25 |
| CA2679097A1 (en) | 2008-09-12 |
| JP2010519903A (ja) | 2010-06-10 |
| AU2008223280A1 (en) | 2008-09-12 |
| EP2115117A1 (en) | 2009-11-11 |
| CN101622337A (zh) | 2010-01-06 |
| US7718430B2 (en) | 2010-05-18 |
| CN101622337B (zh) | 2013-04-24 |
| JP5149313B2 (ja) | 2013-02-20 |
| WO2008109200A1 (en) | 2008-09-12 |
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