JP5122279B2 - 放射線を用いた治療及び／又は化学療法の前に癌を事前感作する方法、及び新規のサイトカイン混合物 - Google Patents

放射線を用いた治療及び／又は化学療法の前に癌を事前感作する方法、及び新規のサイトカイン混合物 Download PDF

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JP5122279B2
JP5122279B2 JP2007519321A JP2007519321A JP5122279B2 JP 5122279 B2 JP5122279 B2 JP 5122279B2 JP 2007519321 A JP2007519321 A JP 2007519321A JP 2007519321 A JP2007519321 A JP 2007519321A JP 5122279 B2 JP5122279 B2 JP 5122279B2
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range
ratio
therapeutic agent
tumor
interleukin
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JP2008505082A5 (enExample
JP2008505082A (ja
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アヤル テイラー，
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セル‐サイ コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2007519321A 2004-06-29 2005-06-28 放射線を用いた治療及び／又は化学療法の前に癌を事前感作する方法、及び新規のサイトカイン混合物 Expired - Fee Related JP5122279B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/878,563 US20050002899A1 (en) 2003-07-03 2004-06-29 Method of pre-sensitizing cancer prior to treament with radiation and/or chemotherapy and a novel cytokine mixture
US10/878,563 2004-06-29
PCT/US2005/022678 WO2006004633A2 (en) 2004-06-29 2005-06-28 A method of pre-sensitizing cancer prior to treament with radiation and/or chemotherapy and a novel cytokine mixture

Publications (3)

Publication Number Publication Date
JP2008505082A JP2008505082A (ja) 2008-02-21
JP2008505082A5 JP2008505082A5 (enExample) 2008-08-21
JP5122279B2 true JP5122279B2 (ja) 2013-01-16

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ID=35783284

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JP2007519321A Expired - Fee Related JP5122279B2 (ja) 2004-06-29 2005-06-28 放射線を用いた治療及び／又は化学療法の前に癌を事前感作する方法、及び新規のサイトカイン混合物

Country Status (8)

Country Link
US (1) US20050002899A1 (enExample)
EP (1) EP1773368B1 (enExample)
JP (1) JP5122279B2 (enExample)
CN (1) CN101014354A (enExample)
AU (1) AU2005260053A1 (enExample)
CA (1) CA2571598A1 (enExample)
ES (1) ES2581978T3 (enExample)
WO (1) WO2006004633A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6896879B2 (en) * 2003-07-03 2005-05-24 Cel-Sci Corporation Method of pre-sensitizing cancer prior to treatment with radiation and/or chemotherapy and a novel cytokine mixture
US20060263368A1 (en) * 2005-01-10 2006-11-23 Research Development Foundation Targeted chimeric molecules for cancer therapy
CN100344325C (zh) * 2005-10-17 2007-10-24 华南师范大学 一种治疗宫颈癌的药物及其制备方法与应用
US20080131396A1 (en) * 2006-12-04 2008-06-05 Cel-Sci Corp. Method for altering the CD4/CD8 ratio and the mononuclear cellular infiltrate into a tumor
CN102166347B (zh) * 2011-04-02 2013-12-11 广州市恺泰生物科技有限公司 一种白细胞介素-12的药物新用途
WO2025019822A1 (en) * 2023-07-19 2025-01-23 Istari Oncology, Inc. Methods of treatment with a chimeric poliovirus in patients with glioblastoma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69533941T2 (de) * 1994-11-17 2005-12-29 University Of South Florida, Tampa Verfahren zur herstellung eines arzneimittels zur behandlung des sekundärimmunmangels
CA2950109C (en) * 2000-10-27 2019-02-19 John W. Hadden Vaccine immunotherapy for immune suppressed patients
US6896879B2 (en) * 2003-07-03 2005-05-24 Cel-Sci Corporation Method of pre-sensitizing cancer prior to treatment with radiation and/or chemotherapy and a novel cytokine mixture
US20060257357A1 (en) * 2005-05-10 2006-11-16 Cel-Sci Corporation Method for modulating HLA class II tumor cell surface expression with a cytokine mixture

Also Published As

Publication number Publication date
EP1773368B1 (en) 2016-05-04
EP1773368A2 (en) 2007-04-18
CN101014354A (zh) 2007-08-08
WO2006004633A3 (en) 2006-03-16
ES2581978T3 (es) 2016-09-08
EP1773368A4 (en) 2009-08-05
JP2008505082A (ja) 2008-02-21
WO2006004633A2 (en) 2006-01-12
CA2571598A1 (en) 2006-01-12
AU2005260053A1 (en) 2006-01-12
US20050002899A1 (en) 2005-01-06

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