CN101014354A - 在放射和/或化学疗法治疗前预敏化癌症的方法和新的细胞因子混合物 - Google Patents

在放射和/或化学疗法治疗前预敏化癌症的方法和新的细胞因子混合物 Download PDF

Info

Publication number
CN101014354A
CN101014354A CNA2005800291699A CN200580029169A CN101014354A CN 101014354 A CN101014354 A CN 101014354A CN A2005800291699 A CNA2005800291699 A CN A2005800291699A CN 200580029169 A CN200580029169 A CN 200580029169A CN 101014354 A CN101014354 A CN 101014354A
Authority
CN
China
Prior art keywords
ratio
interleukin
free
mitogen
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800291699A
Other languages
English (en)
Chinese (zh)
Inventor
E·塔洛尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cel Sci Corp
Original Assignee
Cel Sci Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cel Sci Corp filed Critical Cel Sci Corp
Publication of CN101014354A publication Critical patent/CN101014354A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA2005800291699A 2004-06-29 2005-06-28 在放射和/或化学疗法治疗前预敏化癌症的方法和新的细胞因子混合物 Pending CN101014354A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/878,563 US20050002899A1 (en) 2003-07-03 2004-06-29 Method of pre-sensitizing cancer prior to treament with radiation and/or chemotherapy and a novel cytokine mixture
US10/878,563 2004-06-29

Publications (1)

Publication Number Publication Date
CN101014354A true CN101014354A (zh) 2007-08-08

Family

ID=35783284

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800291699A Pending CN101014354A (zh) 2004-06-29 2005-06-28 在放射和/或化学疗法治疗前预敏化癌症的方法和新的细胞因子混合物

Country Status (8)

Country Link
US (1) US20050002899A1 (enExample)
EP (1) EP1773368B1 (enExample)
JP (1) JP5122279B2 (enExample)
CN (1) CN101014354A (enExample)
AU (1) AU2005260053A1 (enExample)
CA (1) CA2571598A1 (enExample)
ES (1) ES2581978T3 (enExample)
WO (1) WO2006004633A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102166347A (zh) * 2011-04-02 2011-08-31 广州市恺泰生物科技有限公司 一种白细胞介素-12的药物新用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6896879B2 (en) * 2003-07-03 2005-05-24 Cel-Sci Corporation Method of pre-sensitizing cancer prior to treatment with radiation and/or chemotherapy and a novel cytokine mixture
US20060263368A1 (en) * 2005-01-10 2006-11-23 Research Development Foundation Targeted chimeric molecules for cancer therapy
CN100344325C (zh) * 2005-10-17 2007-10-24 华南师范大学 一种治疗宫颈癌的药物及其制备方法与应用
US20080131396A1 (en) * 2006-12-04 2008-06-05 Cel-Sci Corp. Method for altering the CD4/CD8 ratio and the mononuclear cellular infiltrate into a tumor
WO2025019822A1 (en) * 2023-07-19 2025-01-23 Istari Oncology, Inc. Methods of treatment with a chimeric poliovirus in patients with glioblastoma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69533941T2 (de) * 1994-11-17 2005-12-29 University Of South Florida, Tampa Verfahren zur herstellung eines arzneimittels zur behandlung des sekundärimmunmangels
CA2950109C (en) * 2000-10-27 2019-02-19 John W. Hadden Vaccine immunotherapy for immune suppressed patients
US6896879B2 (en) * 2003-07-03 2005-05-24 Cel-Sci Corporation Method of pre-sensitizing cancer prior to treatment with radiation and/or chemotherapy and a novel cytokine mixture
US20060257357A1 (en) * 2005-05-10 2006-11-16 Cel-Sci Corporation Method for modulating HLA class II tumor cell surface expression with a cytokine mixture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102166347A (zh) * 2011-04-02 2011-08-31 广州市恺泰生物科技有限公司 一种白细胞介素-12的药物新用途
CN102166347B (zh) * 2011-04-02 2013-12-11 广州市恺泰生物科技有限公司 一种白细胞介素-12的药物新用途

Also Published As

Publication number Publication date
EP1773368B1 (en) 2016-05-04
EP1773368A2 (en) 2007-04-18
WO2006004633A3 (en) 2006-03-16
ES2581978T3 (es) 2016-09-08
EP1773368A4 (en) 2009-08-05
JP2008505082A (ja) 2008-02-21
WO2006004633A2 (en) 2006-01-12
JP5122279B2 (ja) 2013-01-16
CA2571598A1 (en) 2006-01-12
AU2005260053A1 (en) 2006-01-12
US20050002899A1 (en) 2005-01-06

Similar Documents

Publication Publication Date Title
CN1845757B (zh) 细胞因子混合物在制备由于预敏化癌症的药物中的用途和用于治疗癌症的药物组合物
AU2007276835B2 (en) Vaccine immunotherapy
US20070166279A1 (en) Method for modulating hla class ii tumor cell surface expression with a cytokine mixture
AU6408396A (en) Treatment of acute leukemia with interleukin-10
JPH09508116A (ja) 末梢血単核細胞溶解活性を刺激するためのｉｌ−１０の使用
EP1753452B1 (en) A method for altering the cd4/cd8 ratio and the mononuclear cellular infiltrate into a tumor
EP1773368B1 (en) A method of pre-sensitizing cancer prior to treament with radiation and/or chemotherapy and a novel cytokine mixture
HK1105858A (en) A method of pre-sensitizing cancer prior to treament with radiation and/or chemotherapy and a novel cytokine mixture
US20080131396A1 (en) Method for altering the CD4/CD8 ratio and the mononuclear cellular infiltrate into a tumor
HK1096846A (en) A method of pre-sensitizing cancer prior to treatment with radiation and/or chemotherapy and a novel cytokine mixture
HK1120214A (en) A method for modulating hla class ii tumor cell surface expression with a cytokine mixture
HK1106983A (en) A method for altering the cd4/cd8 ratio and the mononuclear cellular infiltrate into a tumor
HK1193755A (en) A composition for treatment of advanced prostate cancer

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1105858

Country of ref document: HK

C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20070808

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1105858

Country of ref document: HK