JP5102185B2 - 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 - Google Patents
可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 Download PDFInfo
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- JP5102185B2 JP5102185B2 JP2008302894A JP2008302894A JP5102185B2 JP 5102185 B2 JP5102185 B2 JP 5102185B2 JP 2008302894 A JP2008302894 A JP 2008302894A JP 2008302894 A JP2008302894 A JP 2008302894A JP 5102185 B2 JP5102185 B2 JP 5102185B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0443—Modular apparatus
- A61B2560/045—Modular apparatus with a separable interface unit, e.g. for communication
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
- A61B2562/085—Sensors provided with means for identification, e.g. barcodes or memory chips combined with means for recording calibration data
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
- A61B5/743—Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/92—Computer assisted medical diagnostics
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- Molecular Biology (AREA)
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- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Description
一般に、図1のbに関して以下に説明する本発明を使用する例示的な信号調整装置は、案内ワイヤに取付けられた圧力センサを標準的な生理学的(たとえば、血圧)モニタにインターフェースするように設計されている。信号調整装置は、案内ワイヤに取付けられた圧力センサから受取られた信号を処理し、潜在的に異なる信号要求の多くの種々の生理学的モニタの任意のものに正規化された信号を与える。
V=I(excite)×R(sensor) (1)
V=I(excite)×R(sensor) (2)
出力端子68および69(差動増幅器70への入力)の間における差動電圧の変化(両電圧変化の和)は、与えられた圧力に対応している。
Va=Vb (関心を払われている温度範囲に対して) (3)
(IaΔRa)=(IbΔRb) ; したがって (4)
Ib=(IaΔRa)/ΔRb ; および (5)
Ib/Ia=ΔRa/ΔRb (6)
抵抗性センサ素子61に対して:
V(min)=60μA*Rmin=150mV
V(max)=60μA*Rmax=300mV
抵抗性センサ素子62に対して:
Vb(min)=30μA*Rmin=75mV
Vb(max)=90μA*Rmax=450mV
信号調整装置50は、製造中に較正される入力(患者側)および出力(生理学的モニタ側)を共に備えている。信号調整装置50のセンサ入力は、表示および較正転送機能の正確度が高くなるように製造テスト中に較正される。とくに、較正規格(たとえば、差動抵抗を提供するモックセンサ)を信号調整装置50に接続し、入力較正モードに入った後、信号調整装置50はアナログ差動電圧入力をポーリングする。較正入力電圧は読取られ、チェックされる。その後、信号調整装置50は0mmHgに対応した差動電圧入力に関して自動ゼロ機能を行う。次に、信号調整装置50のセンサ入力は、200mmHgを表すように意図された信号入力に対して較正される。200mmHgの読みとゼロの読みとの間の差が読みの3%(すなわち、200mmHgで+/−6mmHg)より大きい場合、決定的エラーが登録される。その差が3%(すなわち、+/−6mmHg)以内である場合、200mmHgでの実際の値と理論上の値(ゼロポイントに基づいた)との間の差は記憶され、信号調整装置に接続された各ワイヤに対する利得DACコードを修正するために使用される。
案内ワイヤ56の“入力”較正に関して、案内ワイヤ56は、信号調整装置50に接続されたときにセンサ特性記述データをEEPROMから供給する。EEPROMの読取り/書込み機能は、当業者によく知られている標準的な2線式直列インターフェース(データすなわち“SDA”およびクロックすなわち“SCL”)を介して行われる。接続された案内ワイヤ取付けセンサはそれぞれ、特定の圧力/温度応答特性を有するピエゾ抵抗圧力感知素子を備えている。製造中、圧力/温度応答特性が決定され、矛盾しない出力を生じる信号調整値は、案内ワイヤのハウジング上に取付けられたEEPROM内に記憶される。これらの値には、温度係数オフセット電流、信号調整利得、ポジションオフセットデフォルト値、およびチェックサムが含まれる。これらの値は、感知された圧力を表すセンサ電流および差動電圧を修正するために上述の信号調整DACに適応される。
信号調整装置50は、案内ワイヤに取付けられたEEPROMの内容をそのDACに供給し、センサ60が適切に接続されていることを確認した後、ケーブル54を介して生理学的モニタ52に与えられるその出力をテストする。信号調整装置50から生理学的モニタ52への出力は、オペレータが生理学的モニタ52の出力を介してオフセットおよび利得を確認することを可能にするために0mmHgから200mmHgまで1/2秒ごとに10mmHgづつ増加するようにパルス駆動される。
ステップ=ΔADCカウント*(ボルト/ADCカウント)*(ステップ/ボルト)*1/構成利得
(7)
ここで、構成利得=可変利得のベース+(利得DACコード*利得/DACコード)である。
構成利得=5+(421*95/4096)=15(近似的に)
を生じさせる。
ボルト/ADCカウント=Ref Volt/4096
ここで、ボルト/(ADCカウント)=2.5/4096
Q15への変換は$0014の値を表現する
ゼロポイント−測定されたゼロ=ΔADCカウント、および
ステップの数(+/−)=ΔADCカウント/ステップ当りのADCカウント
調節が可能である(すなわち、DACが現在8である場合、マイナス10の値はDACに対する負の(エラーのある)値を表現する)か否かを決定するために、計算されたステップ数が現在のオフセットと比較される。
ランモードにおいて、信号調整装置50は、センサ60に与えられた圧力変化を示す差動アナログ電圧信号を受取って、対応した圧力信号を計算し、ケーブル54により生理学的モニタ52に出力する。LCD80は“ランニング”を示す。信号調整装置50に対するサンプリングおよび更新レートは血圧変化レートに適応するように十分に高く、マイクロ制御装置が動作するように十分なパワーが存在することを保証するように十分に低い。例示的なサンプリングレートはほぼ4ミリ秒毎である。しかしながら、当業者は、上述のファクタを考慮したとき、広範囲のサンプリングレートが満足できるものであることを認識するであろう。
Claims (8)
- 1対の抵抗性感知素子を備えた血管内測定装置と生理学的モニタとの間に挿入可能に構成され、生理学的モニタと血管内測定装置との間の適合性の設定を容易にする信号調整装置において、
血管内測定装置の抵抗性感知素子の対を独立的に駆動する2つの別々の励起信号を供給するセンサ電流源と、
血管内測定装置に対する固定された温度補償較正値を受取るデータ入力と、
前記抵抗性感知素子の対における温度変化を補償するために前記抵抗性感知素子の対の少なくとも一方に調節電流を供給する可変電流源とを具備しており、
調節電流は、固定された温度補償較正値から得られる、信号調整装置。 - 前記可変電流源は、生理学的モニタによって供給された励起信号によってパワーを供給される請求項1記載の信号調整装置。
- 前記可変電流源は、デジタルアナログ変換器を含んでいる請求項1記載の信号調整装置。
- 前記血管内測定装置は、血管内の圧力を感知するのに適切な大きさの圧力センサを含んでいる請求項1記載の信号調整装置。
- 前記生理学的モニタによって供給された前記励起信号は約20mArms未満である請求項2記載の信号調整装置。
- 前記生理学的モニタによって供給された前記励起信号は交流電流信号である請求項2記載の信号調整装置。
- 前記生理学的モニタによって供給された前記励起信号は方形波信号である請求項2記載の信号調整装置。
- 前記抵抗性感知素子の対は、血管内の圧力を感知するのに適切な大きさの圧力センサのコンポーネントである請求項1記載の信号調整装置。
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US09/861,464 US6585660B2 (en) | 2001-05-18 | 2001-05-18 | Signal conditioning device for interfacing intravascular sensors having varying operational characteristics to a physiology monitor |
US09/861,464 | 2001-05-18 |
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JP2002591055A Division JP4259880B2 (ja) | 2001-05-18 | 2002-04-22 | 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 |
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JP2009136675A JP2009136675A (ja) | 2009-06-25 |
JP5102185B2 true JP5102185B2 (ja) | 2012-12-19 |
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JP2002591055A Expired - Lifetime JP4259880B2 (ja) | 2001-05-18 | 2002-04-22 | 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 |
JP2008302894A Expired - Lifetime JP5102185B2 (ja) | 2001-05-18 | 2008-11-27 | 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 |
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EP (2) | EP1392160A4 (ja) |
JP (2) | JP4259880B2 (ja) |
CA (1) | CA2446986A1 (ja) |
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JP2009136675A (ja) | 2009-06-25 |
WO2002094339A2 (en) | 2002-11-28 |
JP4259880B2 (ja) | 2009-04-30 |
WO2002094339A3 (en) | 2003-02-20 |
US20020173724A1 (en) | 2002-11-21 |
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