JP4259880B2 - 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 - Google Patents
可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 Download PDFInfo
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- JP4259880B2 JP4259880B2 JP2002591055A JP2002591055A JP4259880B2 JP 4259880 B2 JP4259880 B2 JP 4259880B2 JP 2002591055 A JP2002591055 A JP 2002591055A JP 2002591055 A JP2002591055 A JP 2002591055A JP 4259880 B2 JP4259880 B2 JP 4259880B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0443—Modular apparatus
- A61B2560/045—Modular apparatus with a separable interface unit, e.g. for communication
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
- A61B2562/085—Sensors provided with means for identification, e.g. barcodes or memory chips combined with means for recording calibration data
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
- A61B5/743—Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/92—Computer assisted medical diagnostics
Description
一般に、図1のbに関して以下に説明する本発明を使用する例示的な信号調整装置は、案内ワイヤに取付けられた圧力センサを標準的な生理学的(たとえば、血圧)モニタにインターフェースするように設計されている。信号調整装置は、案内ワイヤに取付けられた圧力センサから受取られた信号を処理し、潜在的に異なる信号要求の多くの種々の生理学的モニタの任意のものに正規化された信号を与える。
V=I(excite)×R(sensor) (1)
V=I(excite)×R(sensor) (2)
出力端子68および69(差動増幅器70への入力)の間における差動電圧の変化(両電圧変化の和)は、与えられた圧力に対応している。
Va=Vb (関心を払われている温度範囲に対して) (3)
(IaΔRa)=(IbΔRb) ; したがって (4)
Ib=(IaΔRa)/ΔRb ; および (5)
Ib/Ia=ΔRa/ΔRb (6)
抵抗性センサ素子61に対して:
V(min)=60μA*Rmin=150mV
V(max)=60μA*Rmax=300mV
抵抗性センサ素子62に対して:
Vb(min)=30μA*Rmin=75mV
Vb(max)=90μA*Rmax=450mV
るために長い時間遅延を有している。故障検出回路は3つの故障状態信号をライン186によりマイクロ制御装置140に供給する。2つのラインはセンサ60上の2つの抵抗性センサ素子61および62のそれぞれに対する短絡を識別する。第3のラインは、案内ワイヤ56が信号調整装置50に接続されていない場合を識別する。
信号調整装置50は、製造中に較正される入力(患者側)および出力(生理学的モニタ側)を共に備えている。信号調整装置50のセンサ入力は、表示および較正転送機能の正確度が高くなるように製造テスト中に較正される。とくに、較正規格(たとえば、差動抵抗を提供するモックセンサ)を信号調整装置50に接続し、入力較正モードに入った後、信号調整装置50はアナログ差動電圧入力をポーリングする。較正入力電圧は読取られ、チェックされる。その後、信号調整装置50は0mmHgに対応した差動電圧入力に関して自動ゼロ機能を行う。次に、信号調整装置50のセンサ入力は、200mmHgを表すように意図された信号入力に対して較正される。200mmHgの読みとゼロの読みとの間の差が読みの3%(すなわち、200mmHgで+/−6mmHg)より大きい場合、決定的エラーが登録される。その差が3%(すなわち、+/−6mmHg)以内である場合、200mmHgでの実際の値と理論上の値(ゼロポイントに基づいた)との間の差は記憶され、信号調整装置に接続された各ワイヤに対する利得DACコードを修正するために使用される。
案内ワイヤ56の“入力”較正に関して、案内ワイヤ56は、信号調整装置50に接続されたときにセンサ特性記述データをEEPROMから供給する。EEPROMの読取り/書込み機能は、当業者によく知られている標準的な2線式直列インターフェース(データすなわち“SDA”およびクロックすなわち“SCL”)を介して行われる。接続された案内ワイヤ取付けセンサはそれぞれ、特定の圧力/温度応答特性を有するピエゾ抵抗圧力感知素子を備えている。製造中、圧力/温度応答特性が決定され、矛盾しない出力を生じる信号調整値は、案内ワイヤのハウジング上に取付けられたEEPROM内に記憶される。これらの値には、温度係数オフセット電流、信号調整利得、ポジションオフセットデフォルト値、およびチェックサムが含まれる。これらの値は、感知された圧力を表すセンサ電流および差動電圧を修正するために上述の信号調整DACに適応される。
信号調整装置50は、案内ワイヤに取付けられたEEPROMの内容をそのDACに供給し、センサ60が適切に接続されていることを確認した後、ケーブル54を介して生理学的モニタ52に与えられるその出力をテストする。信号調整装置50から生理学的モニタ52への出力は、オペレータが生理学的モニタ52の出力を介してオフセットおよび利得を確認することを可能にするために0mmHgから200mmHgまで1/2秒ごとに10mmHgづつ増加するようにパルス駆動される。
ステップ=ΔADCカウント*(ボルト/ADCカウント)*(ステップ/ボルト)*1/構成利得
(7)
ここで、構成利得=可変利得のベース+(利得DACコード*利得/DACコード)である。
構成利得=5+(421*95/4096)=15(近似的に)
を生じさせる。
ボルト/ADCカウント=Ref Volt/4096
ここで、ボルト/(ADCカウント)=2.5/4096
Q15への変換は$0014の値を表現する
ゼロポイント−測定されたゼロ=ΔADCカウント、および
ステップの数(+/−)=ΔADCカウント/ステップ当りのADCカウント
調節が可能である(すなわち、DACが現在8である場合、マイナス10の値はDACに対する負の(エラーのある)値を表現する)か否かを決定するために、計算されたステップ数が現在のオフセットと比較される。
ランモードにおいて、信号調整装置50は、センサ60に与えられた圧力変化を示す差動アナログ電圧信号を受取って、対応した圧力信号を計算し、ケーブル54により生理学的モニタ52に出力する。LCD80は“ランニング”を示す。信号調整装置50に対するサンプリングおよび更新レートは血圧変化レートに適応するように十分に高く、マイクロ制御装置が動作するように十分なパワーが存在することを保証するように十分に低い。例示的なサンプリングレートはほぼ4ミリ秒毎である。しかしながら、当業者は、上述のファクタを考慮したとき、広範囲のサンプリングレートが満足できるものであることを認識するであろう。
Claims (14)
- 生理学的モニタと種々の血管内測定装置との間に挿入可能であり、生理学的モニタと種々の血管内測定装置との間の適合性の設定を容易にする信号調整装置において、
取付け可能な血管内測定装置により支持されているセンサを励起するセンサ駆動信号を供給し、センサ測定信号を供給するセンサインターフェース回路と、
プログラムされたタスクを行う処理装置と、
パワーを励起するための励起信号を生理学的モニタから受取るための入力と、センサ測定信号にしたがって発生された出力測定信号を生理学的モニタに送信する出力とを備えている生理学的モニタインターフェースと、
前記励起信号によって供給されたパワーを少なくとも処理装置に供給する信号変換器を含んでいる電源回路とを具備している信号調整装置。 - 励起信号は交流電流信号である請求項1記載の信号調整装置。
- センサインターフェース回路は、フレキシブルな細長い部材の上に取付けられた圧力センサにセンサ駆動信号を供給するためのケーブルを受けるように構成されている請求項1記載の信号調整装置。
- 励起信号によって供給されたパワーの一部分は、アナログ信号を提供する出力段により受取られる請求項1記載の信号調整装置。
- さらに、励起信号によってパワーを供給される可視的ディスプレイを備えている請求項1記載の信号調整装置。
- さらに、励起信号によってパワーを供給される温度補償回路を備えている請求項1記載の信号調整装置。
- 励起信号はセンサ駆動信号にパワーを供給する請求項1記載の信号調整装置。
- センサインターフェース回路はさらに、センサ駆動信号を固体状態の血管内圧力センサに送信するケーブル用の接続部を備えている請求項1記載の信号調整装置。
- 血管内の血流特性を決定するために血管内で測定を行うシステムにおいて、
センサが取付けられたフレキシブルな細長い部材と、
センサを信号調整装置に電気的に接続するケーブルとを具備しており、
前記信号調整装置は、
取付け可能な血管内測定装置により支持されているセンサを励起するセンサ駆動信号を供給し、センサ測定信号を供給するセンサインターフェース回路と、
プログラムされたタスクを行う処理装置と、
パワーを励起するための励起信号を生理学的モニタから受取るための入力と、センサ測定信号にしたがって発生された出力測定信号を生理学的モニタに送信する出力とを備えている生理学的モニタインターフェースと、
前記励起信号によって供給されたパワーを少なくとも処理装置に供給する信号変換器を含んでいる電源回路とを備えているシステム。 - 励起信号は方形波信号である請求項9記載のシステム。
- さらに、把持式分数フローリザーブ計算器を備えている請求項9記載のシステム。
- 把持式分数フローリザーブ計算器は、第1の測定された圧力に対応した分子スケールおよび第2の測定された圧力に対応した分母スケールとを少なくとも含むスライドルールメカニズムを含んでいる請求項11記載のシステム。
- 第1の測定された圧力は平均末端圧力であり、第2の測定された圧力は平均大動脈圧力である請求項12記載のシステム。
- スライドルールメカニズムは、計算された分数フローリザーブを解釈するための1組の指示を含んでいる請求項13記載のシステム。
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US09/861,464 US6585660B2 (en) | 2001-05-18 | 2001-05-18 | Signal conditioning device for interfacing intravascular sensors having varying operational characteristics to a physiology monitor |
PCT/US2002/012715 WO2002094339A2 (en) | 2001-05-18 | 2002-04-22 | Signal conditioning device for interfacing intravascular sensors |
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JP2008302894A Division JP5102185B2 (ja) | 2001-05-18 | 2008-11-27 | 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 |
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JP2008302894A Expired - Lifetime JP5102185B2 (ja) | 2001-05-18 | 2008-11-27 | 可変動作特性を有する血管内センサを生理学的モニタにインターフェースする信号調整装置 |
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EP (2) | EP1800597A3 (ja) |
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CA (1) | CA2446986A1 (ja) |
WO (1) | WO2002094339A2 (ja) |
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R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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EXPY | Cancellation because of completion of term |