JP5095894B2 - リポタンパク質リパーゼ（ｌｐｌ）変異体治療薬 - Google Patents
リポタンパク質リパーゼ（ｌｐｌ）変異体治療薬 Download PDFInfo
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Priority Applications (1)
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|---|---|---|---|
| US12/898,684 US20110201673A1 (en) | 1999-06-24 | 2010-10-05 | Lpl variant therapeutics |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99202048.7 | 1999-06-24 | ||
| EP99202048 | 1999-06-24 | ||
| PCT/CA2000/000762 WO2001000220A2 (en) | 1999-06-24 | 2000-06-23 | Lipoprotein lipase (lpl) variant therapeutics |
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| JP2003503355A JP2003503355A (ja) | 2003-01-28 |
| JP2003503355A5 JP2003503355A5 (enExample) | 2007-08-09 |
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| EP (1) | EP1200117B1 (enExample) |
| JP (1) | JP5095894B2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE602005015687D1 (de) * | 2004-03-02 | 2009-09-10 | Cellectar Inc | Phospholipid-analoga für die behandlung von krebs |
| ES2306163T3 (es) * | 2004-06-21 | 2008-11-01 | Amsterdam Molecular Therapeutics B.V. | Tratamiento de esteatohepatitis no alcoholica (nash). |
| PT3272872T (pt) | 2005-10-20 | 2020-06-26 | Uniqure Ip Bv | Vetores aav melhorados produzidos em células de insetos |
| WO2007148971A2 (en) | 2006-06-21 | 2007-12-27 | Amsterdam Molecular Therapeutics B.V. | Vectors with modified initiation codon for the translation of aav-rep78 useful for production of aav in insect cells |
| HUE029744T2 (en) | 2007-07-26 | 2017-04-28 | Uniqure Ip Bv | Baculoviral vectors comprising repeated coding sequences with differential codon biases |
| WO2009030254A1 (en) * | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| EP2432497A1 (en) * | 2009-05-18 | 2012-03-28 | Amsterdam Molecular Therapeutics (AMT) IP B.V. | Use of lipoprotein lipase (lpl) in therapy |
| DK3708192T3 (da) | 2009-06-12 | 2023-11-06 | Cellectar Inc | Etherphospholipidforbindelser til behandling af cancer og billeddannelse og detektering af cancerstamceller |
| EP2545165B1 (en) | 2010-03-11 | 2020-07-29 | uniQure IP B.V. | Mutated rep encoding sequences for use in aav production |
| WO2011122950A1 (en) | 2010-04-01 | 2011-10-06 | Amsterdam Molecular Therapeutics (Amt) Ip B.V. | Monomeric duplex aav vectors |
| SG10201604810UA (en) | 2012-02-07 | 2016-08-30 | Global Bio Therapeutics Inc | Compartmentalized method of nucleic acid delivery and compositions and uses thereof |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
| WO2015137802A1 (en) | 2014-03-10 | 2015-09-17 | Uniqure Ip B.V. | Further improved aav vectors produced in insect cells |
| MA41035A (fr) * | 2014-08-19 | 2017-08-15 | Shire Human Genetic Therapies | Lipoprotéine lipase pour le traitement d'affections liées à une hypertriglycéridémie, y compris la pancréatite aiguë |
| EP3458106A4 (en) * | 2016-05-18 | 2020-03-18 | Modernatx, Inc. | POLYNUCLEOTIDS FOR CODING LIPOPROTEIN LIPASE FOR TREATING HYPERLIPIDEMIA |
| CA3045551A1 (en) | 2016-12-16 | 2018-06-21 | Uniqure Ip B.V. | Immunoadsorption |
| US11452749B2 (en) | 2017-07-10 | 2022-09-27 | Uniqure Ip B.V. | Means and methods for AAV gene therapy in humans |
| WO2019016349A1 (en) | 2017-07-20 | 2019-01-24 | Uniqure Ip B.V. | PRODUCTION OF ENHANCED VAA CAPSIDS IN INSECT CELLS |
| CN111527201A (zh) | 2017-12-29 | 2020-08-11 | 优尼科Ip有限公司 | 修饰的病毒载体及其制备和使用方法 |
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| AU695618B2 (en) * | 1994-04-11 | 1998-08-20 | Baylor College Of Medicine | Compositions and methods for gene therapy to treat disease |
| US5658729A (en) * | 1994-10-11 | 1997-08-19 | The University Of British Columbia | Method, reagent and kit for evaluating susceptibility to premature atherosclerosis |
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2000
- 2000-06-23 CA CA2370081A patent/CA2370081C/en not_active Expired - Fee Related
- 2000-06-23 AT AT00943499T patent/ATE404217T1/de active
- 2000-06-23 DE DE60039880T patent/DE60039880D1/de not_active Expired - Lifetime
- 2000-06-23 PT PT00943499T patent/PT1200117E/pt unknown
- 2000-06-23 ES ES00943499T patent/ES2311464T3/es not_active Expired - Lifetime
- 2000-06-23 WO PCT/CA2000/000762 patent/WO2001000220A2/en not_active Ceased
- 2000-06-23 EP EP20000943499 patent/EP1200117B1/en not_active Expired - Lifetime
- 2000-06-23 JP JP2001505929A patent/JP5095894B2/ja not_active Expired - Fee Related
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- 2000-06-23 DK DK00943499T patent/DK1200117T3/da active
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2008
- 2008-11-13 CY CY20081101305T patent/CY1108511T1/el unknown
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2010
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| CY1108511T1 (el) | 2014-04-09 |
| AU5799200A (en) | 2001-01-31 |
| DE60039880D1 (en) | 2008-09-25 |
| JP2003503355A (ja) | 2003-01-28 |
| DK1200117T3 (da) | 2008-11-17 |
| WO2001000220A2 (en) | 2001-01-04 |
| EP1200117A2 (en) | 2002-05-02 |
| WO2001000220A3 (en) | 2001-07-12 |
| CA2370081A1 (en) | 2001-01-04 |
| CA2370081C (en) | 2014-06-03 |
| US20110201673A1 (en) | 2011-08-18 |
| PT1200117E (pt) | 2008-11-26 |
| EP1200117B1 (en) | 2008-08-13 |
| ES2311464T3 (es) | 2009-02-16 |
| ATE404217T1 (de) | 2008-08-15 |
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