JP5088894B2 - 生体適合性組織封止剤および接着剤 - Google Patents
生体適合性組織封止剤および接着剤 Download PDFInfo
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- JP5088894B2 JP5088894B2 JP2008544473A JP2008544473A JP5088894B2 JP 5088894 B2 JP5088894 B2 JP 5088894B2 JP 2008544473 A JP2008544473 A JP 2008544473A JP 2008544473 A JP2008544473 A JP 2008544473A JP 5088894 B2 JP5088894 B2 JP 5088894B2
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- Prior art keywords
- diisocyanate
- composition
- biocompatible
- functionalized
- group
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/48—Polyethers
- C08G18/4804—Two or more polyethers of different physical or chemical nature
- C08G18/4812—Mixtures of polyetherdiols with polyetherpolyols having at least three hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/62—Polymers of compounds having carbon-to-carbon double bonds
- C08G18/6212—Polymers of alkenylalcohols; Acetals thereof; Oxyalkylation products thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/65—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
- C08G18/66—Compounds of groups C08G18/42, C08G18/48, or C08G18/52
- C08G18/6666—Compounds of group C08G18/48 or C08G18/52
- C08G18/667—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38
- C08G18/6681—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/32 or C08G18/3271 and/or polyamines of C08G18/38
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J175/00—Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
- C09J175/04—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2190/00—Compositions for sealing or packing joints
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Materials For Medical Uses (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
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| US74293905P | 2005-12-06 | 2005-12-06 | |
| US60/742,939 | 2005-12-06 | ||
| PCT/US2006/046554 WO2007067623A2 (en) | 2005-12-06 | 2006-12-06 | Biocompatible tissue sealants and adhesives |
Publications (3)
| Publication Number | Publication Date |
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| JP2009518128A JP2009518128A (ja) | 2009-05-07 |
| JP2009518128A5 JP2009518128A5 (https=) | 2010-11-25 |
| JP5088894B2 true JP5088894B2 (ja) | 2012-12-05 |
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| EP (1) | EP1968617A4 (https=) |
| JP (1) | JP5088894B2 (https=) |
| AU (1) | AU2006321913B2 (https=) |
| CA (1) | CA2628582C (https=) |
| WO (1) | WO2007067623A2 (https=) |
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| US7763769B2 (en) | 2001-02-16 | 2010-07-27 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US7700819B2 (en) | 2001-02-16 | 2010-04-20 | Kci Licensing, Inc. | Biocompatible wound dressing |
| WO2006086510A2 (en) | 2005-02-09 | 2006-08-17 | Tyco Healthcare Group Lp | Synthetic sealants |
| US8044234B2 (en) * | 2005-05-05 | 2011-10-25 | Tyco Healthcare Group Lp | Bioabsorbable surgical composition |
| US20100100124A1 (en) * | 2005-05-05 | 2010-04-22 | Tyco Healthcare Group Lp | Bioabsorbable surgical composition |
| US20090177226A1 (en) * | 2005-05-05 | 2009-07-09 | Jon Reinprecht | Bioabsorbable Surgical Compositions |
| WO2007067625A2 (en) | 2005-12-06 | 2007-06-14 | Tyco Healthcare Group Lp | Bioabsorbable surgical composition |
| EP1962867B1 (en) * | 2005-12-06 | 2013-06-19 | Covidien LP | Biocompatible surgical compositions |
| WO2007067624A2 (en) * | 2005-12-06 | 2007-06-14 | Tyco Healthcare Group Lp | Bioabsorbable compounds and compositions containing them |
| JP2009518142A (ja) * | 2005-12-08 | 2009-05-07 | タイコ ヘルスケア グループ リミテッド パートナーシップ | 生体適合性外科用組成物 |
| CN101854960B (zh) | 2006-12-15 | 2014-06-25 | 生命连结有限公司 | 明胶-转谷氨酰胺酶止血敷料和密封材料 |
| US8133484B2 (en) | 2006-12-15 | 2012-03-13 | Lifebond Ltd | Hemostatic materials and dressing |
| US20080293910A1 (en) * | 2007-05-24 | 2008-11-27 | Tyco Healthcare Group Lp | Adhesive formulatiions |
| US7858835B2 (en) | 2007-06-27 | 2010-12-28 | Tyco Healthcare Group Lp | Foam control for synthetic adhesive/sealant |
| US8500947B2 (en) * | 2007-11-15 | 2013-08-06 | Covidien Lp | Speeding cure rate of bioadhesives |
| US8263704B2 (en) * | 2008-04-23 | 2012-09-11 | Tyco Healthcare Group Lp | Bioabsorbable surgical composition |
| EP2487206A3 (en) | 2008-06-18 | 2012-11-28 | Lifebond Ltd | Cross-linkable gelatin-based compositions |
| US8349987B2 (en) | 2009-02-19 | 2013-01-08 | Covidien Lp | Adhesive formulations |
| US20110015672A1 (en) * | 2009-07-17 | 2011-01-20 | Tyco Healthcare Group Lp | Method for Coating a Medical Device |
| US20110066123A1 (en) | 2009-09-15 | 2011-03-17 | Aidan Marcus Tout | Medical dressings, systems, and methods employing sealants |
| US9066991B2 (en) | 2009-12-22 | 2015-06-30 | Lifebond Ltd. | Modification of enzymatic crosslinkers for controlling properties of crosslinked matrices |
| US9119605B2 (en) | 2010-05-06 | 2015-09-01 | Zimmer, Inc. | Synthetic polymer adhesives and methods for making, using and delivering the same |
| DK2600910T3 (en) | 2010-08-05 | 2016-04-04 | Lifebond Ltd | Wound dressings and adhesives COMPREHENSIVE DRYING FORMATIONS |
| DE102012107535A1 (de) * | 2012-08-16 | 2014-02-20 | Bess Pro Gmbh | Bioresorbierbare Klebstoffe und deren Verwendung im medizinischen Bereich |
| US10016454B2 (en) | 2012-12-04 | 2018-07-10 | Cohera Medical, Inc. | Silane-containing moisture-curable tissue sealant |
| US9295752B1 (en) * | 2014-09-30 | 2016-03-29 | Covidien Lp | Bioadhesive for occluding vessels |
| CN111194226B (zh) * | 2017-09-06 | 2022-10-14 | 南洋理工大学 | 吸湿性、交联涂层和生物粘合剂 |
| CN112437678A (zh) * | 2018-05-04 | 2021-03-02 | 先进医疗解决方案以色列(西兰迪斯)公司 | 重构和混合系统 |
| US11998654B2 (en) | 2018-07-12 | 2024-06-04 | Bard Shannon Limited | Securing implants and medical devices |
| AU2020275382B2 (en) * | 2019-05-10 | 2026-01-22 | Massachusetts Institute Of Technology | Dry double-sided material for adhesion of wet tissues and devices |
| CN114574140B (zh) * | 2022-04-22 | 2024-07-23 | 东北师范大学 | 一种具有可控性的聚合物胶黏剂及其制备方法 |
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2006
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- 2006-12-06 AU AU2006321913A patent/AU2006321913B2/en not_active Ceased
- 2006-12-06 CA CA 2628582 patent/CA2628582C/en not_active Expired - Fee Related
- 2006-12-06 EP EP06844892A patent/EP1968617A4/en not_active Withdrawn
- 2006-12-06 US US11/635,294 patent/US7998466B2/en not_active Expired - Fee Related
- 2006-12-06 JP JP2008544473A patent/JP5088894B2/ja not_active Expired - Fee Related
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| CA2628582C (en) | 2015-03-31 |
| WO2007067623A2 (en) | 2007-06-14 |
| AU2006321913B2 (en) | 2012-08-02 |
| WO2007067623A3 (en) | 2008-02-07 |
| US7998466B2 (en) | 2011-08-16 |
| AU2006321913A1 (en) | 2007-06-14 |
| JP2009518128A (ja) | 2009-05-07 |
| EP1968617A4 (en) | 2012-05-02 |
| EP1968617A2 (en) | 2008-09-17 |
| CA2628582A1 (en) | 2007-06-14 |
| US20070128152A1 (en) | 2007-06-07 |
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