JP5047527B2 - Topical skin preparation - Google Patents

Description

This invention is a skin external preparation characterized by containing a snow tea extract and a specific plant extract as an active ingredient, and by using a specific plant extract in combination with the snow tea extract, The melanin production inhibitory effect of snow tea extract is synergistically enhanced, effective in the prevention and improvement of pigmentation, blotches, buckwheat, liver spots, etc. after sunburn, and the skin whitening effect is significantly improved Related to high whitening cosmetics.

Conventionally, whitening cosmetics have been screened for ingredients that have the action of inhibiting melanin production or reducing the produced melanin pigment in order to prevent or improve skin darkening due to ultraviolet rays and skin pigmentation such as spots and freckles. Has been formulated. For example, ascorbic acid, cysteine, hydroquinone, and derivatives thereof are used. However, ascorbic acid, cysteine, hydroquinone, and derivatives thereof are all susceptible to oxidation-reduction reactions and are unstable, and satisfactory results are not obtained in terms of sufficient storage stability and whitening effect.

On the other hand, the extract of Prunus lannesiana, Prunus yedoensis, peach (Prunus)
persica), plum (Prunus mume), azalea (Rhododendron) azalea, Rhododendron hirado, mountain azalea (Rhododendron)
obtusum), Hibiscus syriacus, Hibiscus mutabilis, Rosa, Rose, Rose
It has been reported that mucopolysaccharide fragmentation-inhibiting action can be obtained by containing as an active ingredient one or more selected from various plant extraction groups extracted from petals of each plant consisting of laevigata) ( Japanese Patent No. 3532244) has not been known to obtain an excellent skin whitening effect by using each of these plant extracts in combination with a snow tea extract.
Patent No.3532244

In the present invention, it is intended to obtain an external preparation for skin that solves the above problems, has a strong skin melanin production inhibitory action, and has no safety problems such as skin irritation and skin sensitization. It was aimed.

In order to solve the above problems, various studies were conducted, and by using a specific plant extract in combination with the snow tea extract, the production inhibitory action of melanin possessed by the snow tea extract is synergistically enhanced, Moreover, it has been found that an external preparation for skin having no safety problems such as skin irritation and skin sensitization can be obtained, and the present invention has been completed.

That is, according to the present invention, a snow tea extract, a Prunus genus plant extract, a Rhododendron genus plant extract, a Hibiscus genus plant extract, a Rose genus plant extract Provided is a topical skin preparation that contains one or more components selected from among them, has an enhanced whitening effect, and has no safety problems such as skin irritation and skin sensitization. The

The snow tea extract used in the present invention is obtained by charging lichen mossaceae snow tea (Thamnolia vermicularis Ach.) Into water, various suitable organic solvents, and mixed solvents thereof at low temperature and / or Or the thing extracted under heating can be used.

The extraction solvent is not particularly limited. For example, water; lower monohydric alcohols such as methyl alcohol and ethyl alcohol; liquid polyhydric alcohols such as glycerin, propylene glycol and 1,3-butylene glycol; ketones such as acetone and methyl ethyl ketone Alkyl ethers such as ethyl acetate; hydrocarbons such as benzene and hexane; ethers such as diethyl ether; halogenated alkanes such as dichloromethane and chloroform; In particular, a mixed solvent of one or more of water, ethyl alcohol and 1,3-butylene glycol is particularly suitable.

There is no restriction | limiting in particular as an extraction raw material of the snow tea extract used by this invention, Although it can select suitably according to the objective, The whole plant of lichen Musgogaceae snow tea is preferable. The whole snow tea as the extraction raw material is desirably dried after harvesting and used after pulverization or coarse pulverization after drying.

The snow tea extract obtained under the above conditions may be used as the extracted solution, but if necessary, it can be used by appropriately filtering and concentrating it after filtration or the like. I can do it.

The blending amount of the snow tea extract with respect to the external preparation for skin is not particularly limited as long as it is effective, but is preferably 0.001 to 80% by weight, more preferably 0.001 to 1.0% by weight in terms of dry weight.

Examples of the plant extract of the genus Prunus used in the present invention include, for example, the extract of Prunus lannesiana, Yoshino cherry (Prunus)
Examples include yedoensis extract, peach (Prunus persica) extract, and plum (Prunus mume) extract.

Examples of the azalea (Rhododendron) plant extract used in the present invention include, for example, azalea extract, Rhododendron hirado extract, and rhododendron (Rhododendron).
obtusum) extract and the like.

Examples of the plant extract of the genus Hibiscus used in the present invention include, for example, Hibiscus syriacus extract, Fubis (Hibiscus)
mutabilis) extract and the like.

Examples of the plant extract of the genus Rose used in the present invention include a rose extract and a extract of Rosa laevigata.

Furthermore, preparation of the plant extract used for the skin external preparation of this invention is not specifically limited. For example, it is possible to use a product extracted in water, various suitable organic solvents, and mixed solvents thereof and extracted under low temperature and / or warming.

Although the compounding quantity with respect to the skin external preparation of a plant extract will not be specifically limited if it is effective, 0.001-10 weight% is preferable in conversion of dry weight, More preferably, it is 0.001-1.0 weight%.

The extraction solvent is not particularly limited. For example, water; lower monohydric alcohols such as methyl alcohol and ethyl alcohol; liquid polyhydric alcohols such as glycerin, propylene glycol and 1,3-butylene glycol; ketones such as acetone and methyl ethyl ketone Alkyl ethers such as ethyl acetate; hydrocarbons such as benzene and hexane; ethers such as diethyl ether; halogenated alkanes such as dichloromethane and chloroform; In particular, a mixed solvent of one or more of water, ethyl alcohol and 1,3-butylene glycol is particularly suitable.

The extraction raw material of the plant extract used in the present invention is not particularly limited and can be appropriately selected according to the purpose. However, it is desirable to use it after drying, and it is desirable to use after drying or pulverized or coarsely crushed. It may be used. The use site of each plant is not particularly limited, and any plant, flower, leaf, stem, or root may be used.

The plant extract obtained under the above conditions may be used as an extracted solution, but if necessary, it can be used by appropriately filtering and concentrating and pulverizing by filtration or the like. .

The topical skin preparation of the present invention includes cosmetics, quasi-drugs, aqueous components used in pharmaceuticals, oily components, plant extracts, animal extracts, powders, surfactants, oils, alcohol, PH It adjusts, a chelating agent, antiseptic | preservative, antioxidant, a thickener, a pigment | dye, a fragrance | flavor etc. as needed, and is prepared by mixing suitably. The dosage form of the cosmetic of the present invention is not particularly limited, and can be various dosage forms such as lotion, milky lotion, cream, pack, powder, spray, ointment, dispersion, and detergent.

  Hereinafter, preparation of snow tea extract and plant extract according to the present invention, and examples of human effect tests will be shown. Furthermore, although the application prescription example etc. to the cosmetics using the raw material are described, it cannot be overemphasized that it is not limited to the Example described here.

Preparation of Snow Tea Extract The snow tea extract according to the present invention is obtained by adding 100 ml of 50% aqueous ethanol solution to 15 g of dry material of the lichen Muskegoceae snow tea (Thamnolia vermicularis Ach.) And stirring at room temperature occasionally. Extracted for 7 days and filtered to obtain an extract. This extract was concentrated under reduced pressure, and a 25% aqueous ethanol solution was added so that the loss on drying was 1% to obtain samples for each effect test.

Preparation of plant extract
As plants of the genus Sakura (Prunus), petals of Prunus yedoensis, as a plant of the genus Rhododendron, Rhododendron
Obtusum whole plant, Hibiscus genus plant, Hibiscus syriacus petal, Rose genus rose
100 g of 50% ethanol aqueous solution was added to 10 g of each plant dry product of whole plant of Laevigata), extracted for 7 days with occasional stirring at room temperature, and filtered to obtain each extract. Each of these extracts was concentrated under reduced pressure, and a 25% aqueous ethanol solution was added so that the loss on drying was 1%.

Whitening effect confirmation test 1 in humans
As subjects of the first group, 20 women aged 20 to 50 years were used twice a day (morning and evening) for 2 consecutive months, using Comparative Example 1 and Comparative Example 2 for each half face, and the state of the application site was determined. Comparison was made before and after the test to investigate the improvement effect. In this test, the cosmetic shown in paragraph 0051 as Comparative Example 1 was used, and in Comparative Example 2, a cosmetic obtained by removing the snow tea extract from the cosmetic shown in Paragraph 0051 was prepared. Examined. While using cosmetics containing the active ingredient of the present invention every day, the skin whitening effect was tabulated before and after the application for 2 months, and the effect was confirmed. No one complained of skin abnormalities during use. The results are shown in Table 1. The numbers in the table represent the number of people.

<Criteria> Remarkable: The skin spots and dullness were remarkably improved as compared to before application.
Effective: Blemish and dullness of skin improved compared to before application.
Slightly effective: Stain and dullness of skin slightly improved compared to before application.
Invalid: No change compared to before application start.

Table 1 shows the results of a whitening effect confirmation test of the snow tea extract in humans. Although there were many subjects who answered that Comparative Example 1 was slightly more effective, no clear efficacy was observed compared to Comparative Example 2, and sufficient whitening effect was obtained in Comparative Example 1 containing only snow tea extract. I couldn't.

Whitening effect confirmation test 2 in humans
As subjects in the second group, 10 females aged 20 to 50 years were used twice a day (morning and evening) for two consecutive months, using Comparative Example 1 and Example 1 for each half face, and the state of the application site was determined. Comparison was made before and after the test to investigate the improvement effect. At the same time, Example 1 and Comparative Example 3 were used in the same manner by 10 women aged 20 to 50 as subjects in the third group, and the state of the application site was compared before and after the test to examine the improvement effect. In this test, the cosmetic shown in paragraph 0051 was used as Comparative Example 1, the cosmetic shown in Paragraph 0052 was used in Example 1, and the cosmetic obtained by removing Snow Tea Extract from Paragraph 0052 was used in Comparative Example 3. Created and examined the effects of its use. While using cosmetics containing the active ingredient of the present invention every day, the skin whitening effect was tabulated before and after the application for 2 months, and the effect was confirmed. No one complained of skin abnormalities during use. The results are shown in Table 2. The numbers in the table represent the number of people.

<Criteria> Remarkable: The skin spots and dullness were remarkably improved as compared to before application.
Effective: Blemish and dullness of skin improved compared to before application.
Slightly effective: Stain and dullness of skin slightly improved compared to before application.
Invalid: No change compared to before application start.

Table 2 shows the results of the whitening effect confirmation test in humans of the snow tea extract and / or the Yoshino cherry extract. The comparative example 1 which mix | blended only the snow tea extract as an active ingredient, and the comparative example 3 which mix | blended only the Yoshino cherry extract were excellent in Example 1 which used the snow tea extract and the Yoshino cherry extract together. .

Whitening effect confirmation test 3 in humans
As subjects in the fourth group, 10 females aged 20 to 50 years were used twice a day (morning and evening) for 2 consecutive months, using Comparative Example 1 and Example 2 for each half face, and the state of the application site was determined. Comparison was made before and after the test to investigate the improvement effect. At the same time, Example 2 and Comparative Example 4 were used in the same manner by 10 other women aged 20 to 50 as subjects in the fifth group, and the state of the application site was compared before and after the test to examine the improvement effect. In this test, the cosmetic shown in paragraph 0051 was used as Comparative Example 1, the cosmetic shown in Paragraph 0053 was used in Example 2, and the cosmetic obtained by removing Snow Tea Extract from Paragraph 0053 was used in Comparative Example 4. Created and examined the effects of its use. While using cosmetics containing the active ingredient of the present invention every day, the skin whitening effect was tabulated before and after the application for 2 months, and the effect was confirmed. No one complained of skin abnormalities during use. The results are shown in Table 3. The numbers in the table represent the number of people.

<Criteria> Remarkable: The skin spots and dullness were remarkably improved as compared to before application.
Effective: Blemish and dullness of skin improved compared to before application.
Slightly effective: Stain and dullness of skin slightly improved compared to before application.
Invalid: No change compared to before application start.

Table 3 shows the results of a human whitening effect confirmation test of the snow tea extract and / or the pine azalea extract. Compared to Comparative Example 1 in which only the snow tea extract was blended as an active ingredient, and in Comparative Example 4 in which only the pine azalea extract was blended, an excellent whitening effect was observed in Example 2 in which the snow tea extract and the pine azalea extract were combined. It was.

Whitening effect confirmation test 4 in humans
As subjects in the sixth group, 10 females aged 20 to 50 years were used twice a day (morning and evening) for two consecutive months, using Comparative Example 1 and Example 3 for each half face, and the state of the application site was determined. Comparison was made before and after the test to investigate the improvement effect. At the same time, Example 3 and Comparative Example 5 were used in the same manner by 10 other women aged 20 to 50 as subjects in the seventh group, and the state of the application site was compared before and after the test to examine the improvement effect. In this test, the cosmetic shown in paragraph 0051 was used as Comparative Example 1, the cosmetic shown in Paragraph 0054 was used in Example 3, and the cosmetic obtained by removing Snow Tea Extract from Paragraph 0054 was used in Comparative Example 5. Created and examined the effects of its use. While using cosmetics containing the active ingredient of the present invention every day, the skin whitening effect was tabulated before and after the application for 2 months, and the effect was confirmed. No one complained of skin abnormalities during use. The results are shown in Table 4. The numbers in the table represent the number of people.

<Criteria> Remarkable: The skin spots and dullness were remarkably improved as compared to before application.
Effective: Blemish and dullness of skin improved compared to before application.
Slightly effective: Stain and dullness of skin slightly improved compared to before application.
Invalid: No change compared to before application start.

Table 4 shows the results of a whitening effect confirmation test in humans of the snow tea extract and / or the Mukuge extract. Compared to Comparative Example 1 in which only the snow tea extract was blended as an active ingredient, and in Comparative Example 5 in which only the mugwort extract was blended, an excellent whitening effect was observed in Example 3 in which the snow tea extract and the mugwort extract were combined. It was.

Whitening effect confirmation test 5 in humans
As subjects of the eighth group, 10 women aged 20 to 50 years were used twice a day (morning and evening) for two consecutive months, using Comparative Example 1 and Example 4 each half face, and the state of the application site Comparison was made before and after the test to investigate the improvement effect. At the same time, Example 4 and Comparative Example 6 were used in the same manner by another 10 females aged 20 to 50 as subjects in Group 9, and the state of the application site was compared before and after the test to examine the improvement effect. In this test, the cosmetic shown in paragraph 0051 was used as Comparative Example 1, the cosmetic shown in Paragraph 0055 was used in Example 4, and the cosmetic obtained by removing Snow Tea Extract from Paragraph 0055 was used in Comparative Example 6. Created and examined the effects of its use. While using cosmetics containing the active ingredient of the present invention every day, the skin whitening effect was tabulated before and after the application for 2 months, and the effect was confirmed. No one complained of skin abnormalities during use. The results are shown in Table 5. The numbers in the table represent the number of people.

<Criteria> Remarkable: The skin spots and dullness were remarkably improved as compared to before application.
Effective: Blemish and dullness of skin improved compared to before application.
Slightly effective: Stain and dullness of skin slightly improved compared to before application.
Invalid: No change compared to before application start.

Table 5 shows the results of the whitening effect confirmation test in humans of the snow tea extract and / or the Naniwai rose extract. Compared to Comparative Example 1 in which only Snow Tea Extract was blended as an active ingredient, and in Comparative Example 6 in which only Nani Waibara Extract was blended, an excellent whitening effect was observed in Example 4 in which Snow Tea Extract and Nani Waibara Extract were combined. It was.

Whitening effect confirmation test 6 in humans
As subjects of the 10th group, 10 women aged 20 to 50 years were used twice a day (morning and evening) for two consecutive months, each of Comparative Example 1 and Example 5 for each half face, and the state of the application site was Comparison was made before and after the test to investigate the improvement effect. At the same time, Example 5 and Comparative Example 7 were used in the same manner by 10 other women aged 20 to 50 as subjects in the eleventh group, and the state of the application site was compared before and after the test to examine the improvement effect. In this test, the cosmetic shown in paragraph 0051 was used as Comparative Example 1, the cosmetic shown in Paragraph 0056 was used in Example 5, and the cosmetic obtained by removing Snow Tea Extract from Paragraph 0056 was used in Comparative Example 7. Created and examined the effects of its use. While using cosmetics containing the active ingredient of the present invention every day, the skin whitening effect was tabulated before and after the application for 2 months, and the effect was confirmed. No one complained of skin abnormalities during use. The results are shown in Table 6. The numbers in the table represent the number of people.

<Criteria> Remarkable: The skin spots and dullness were remarkably improved as compared to before application.
Effective: Blemish and dullness of skin improved compared to before application.
Slightly effective: Stain and dullness of skin slightly improved compared to before application.
Invalid: No change compared to before application start.

Table 6 shows the results of the whitening effect confirmation test in humans of the snow tea extract and / or the Yoshino cherry extract and the Naniwai rose extract. Comparative Example 1 in which only Snow Tea Extract is blended as an active ingredient, and Comparative Example 7 in which only Yoshino cherry extract and Naniwai Rose Extract are blended, Example 5 in which Snow Tea Extract, Somei Yoshino Extract, and Naniwai Rose Extract are used in combination Excellent whitening effect was observed.

Next, although the example of the formulation example of the cosmetics which mix | blended various components of this invention is shown, this invention is not limited to this.
Examples of cosmetic formulations

(1) Cosmetic cream (wt%)
a) Beeswax ... 2.0
b) Stearyl alcohol ... 5.0
c) Stearic acid: 8.0
d) Squalane ... 10.0
e) Self-emulsifying glyceryl monostearate ... 3.0
f) Polyoxyethylene cetyl ether (20E.O.) ... 1.0
g) Snow tea extract ... 5.0
h) 1,3-Butylene glycol ... 5.0
i) Potassium hydroxide ... 0.3
j) Preservatives / Antioxidants: appropriate amount
k) Purified water: Remainder manufacturing method
Heat up to a) to f) and keep at 80 ° C. G) to l) are heated and dissolved, kept at 80 ° C., and added to a) to f) to emulsify. Add m) at 50 ° C. and cool to 40 ° C. with stirring.

(2) Emulsion (wt%)
a) Beeswax ... 0.5
b) Petrolatum ... 2.0
c) Squalane ... 8.0
d) Sorbitan sesquioleate ... 0.8
e) Polyoxyethylene oleyl ether (20E.O.) ... 1.2
f) Snow tea extract ... 5.0
g) 1,3-Butylene glycol ・ ・ ・ 7.0
h) Carboxyvinyl polymer ... 0.2
i) Potassium hydroxide ... 0.1
j) Purified water: remaining
k) Preservatives / Antioxidants ...
l) Ethanol ... 7.0
Manufacturing method
Heat up to a) to e) and keep at 80 ° C. F) to k) are dissolved by heating, kept at 80 ° C., added to a) to e), emulsified, and cooled to 50 ° C. with stirring. Add l) at 50 ° C and stir cool to 40 ° C.

(3) Emulsion (wt%)
a) Beeswax ... 0.5
b) Petrolatum ... 2.0
c) Squalane ... 8.0
d) Sorbitan sesquioleate ... 0.8
e) Polyoxyethylene oleyl ether (20E.O.) ... 1.2
f) Snow tea extract ... 5.0
g) Yoshino cherry extract ... 1.0
h) 1,3-butylene glycol ... 7.0
i) Carboxyvinyl polymer ... 0.2
j) Potassium hydroxide ... 0.1
k) Purified water: balance
l) Preservatives / Antioxidants ... appropriate amount
m) Ethanol ... 7.0
Manufacturing method
Heat up to a) to e) and keep at 80 ° C. F) to l) are dissolved by heating, kept at 80 ° C., added to a) to e), emulsified, and cooled to 50 ° C. with stirring. Add m) at 50 ° C. and stir cool to 40 ° C.

(4) Emulsion (wt%)
a) Beeswax ... 0.5
b) Petrolatum ... 2.0
c) Squalane ... 8.0
d) Sorbitan sesquioleate ... 0.8
e) Polyoxyethylene oleyl ether (20E.O.) ... 1.2
f) Snow tea extract ... 5.0
g) Azalea extract ... 1.0
h) 1,3-butylene glycol ... 7.0
i) Carboxyvinyl polymer ... 0.2
j) Potassium hydroxide ... 0.1
k) Purified water: balance
l) Preservatives / Antioxidants ... appropriate amount
m) Ethanol ... 7.0
Manufacturing method
Heat up to a) to e) and keep at 80 ° C. F) to l) are dissolved by heating, kept at 80 ° C., added to a) to e), emulsified, and cooled to 50 ° C. with stirring. Add m) at 50 ° C. and stir cool to 40 ° C.

(5) Emulsion (wt%)
a) Beeswax ... 0.5
b) Petrolatum ... 2.0
c) Squalane ... 8.0
d) Sorbitan sesquioleate ... 0.8
e) Polyoxyethylene oleyl ether (20E.O.) ... 1.2
f) Snow tea extract ... 5.0
g) Mukuge extract ... 1.0
h) 1,3-butylene glycol ... 7.0
i) Carboxyvinyl polymer ... 0.2
j) Potassium hydroxide ... 0.1
k) Purified water: balance
l) Preservatives / Antioxidants ... appropriate amount
m) Ethanol ... 7.0
Manufacturing method
Heat up to a) to e) and keep at 80 ° C. F) to l) are dissolved by heating, kept at 80 ° C., added to a) to e), emulsified, and cooled to 50 ° C. with stirring. Add m) at 50 ° C. and stir cool to 40 ° C.

(6) Emulsion (wt%)
a) Beeswax ... 0.5
b) Petrolatum ... 2.0
c) Squalane ... 8.0
d) Sorbitan sesquioleate ... 0.8
e) Polyoxyethylene oleyl ether (20E.O.) ... 1.2
f) Snow tea extract ... 5.0
g) Naniwai rose extract ... 1.0
h) 1,3-butylene glycol ... 7.0
i) Carboxyvinyl polymer ... 0.2
j) Potassium hydroxide ... 0.1
k) Purified water: balance
l) Preservatives / Antioxidants ... appropriate amount
m) Ethanol ... 7.0
Manufacturing method
Heat up to a) to e) and keep at 80 ° C. F) to l) are dissolved by heating, kept at 80 ° C., added to a) to e), emulsified, and cooled to 50 ° C. with stirring. Add m) at 50 ° C. and stir cool to 40 ° C.

(7) Emulsion (wt%)
a) Beeswax ... 0.5
b) Petrolatum ... 2.0
c) Squalane ... 8.0
d) Sorbitan sesquioleate ... 0.8
e) Polyoxyethylene oleyl ether (20E.O.) ... 1.2
f) Snow tea extract ... 5.0
g) Yoshino cherry extract ... 1.0
h) Naniwaibara extract ... 1.0
i) 1,3-Butylene glycol ... 7.0
j) Carboxyvinyl polymer ... 0.2
k) Potassium hydroxide ... 0.1
l) Purified water: balance
m) Preservatives / Antioxidants ...
n) Ethanol ... 7.0
Manufacturing method
Heat up to a) to e) and keep at 80 ° C. F) to m) are heated and dissolved, kept at 80 ° C., added to a) to e), emulsified, and cooled to 50 ° C. with stirring. Add n) at 50 ° C. and stir cool to 40 ° C.

(8) Lotion (wt%)
a) Snow tea extract ... 2.0
b) Yoshino cherry extract ... 1.0
c) Glycerin ... 5.0
d) Polyoxyethylene sorbitan monolaurate (20E.O.) ... 1.0
e) Ethanol ... 6.0
f) Perfume ... appropriate amount
g) Preservatives / Antioxidants ...
h) Purified water: the remainder Manufacturing method a), b), c), d), h) are mixed uniformly. Mix e) -g) uniformly and add to a), b), c), d), h) mixture.

(9) Lotion (wt%)
a) Snow tea extract ... 2.0
b) Azalea extract ... 1.0
c) Glycerin ... 5.0
d) Polyoxyethylene sorbitan monolaurate (20E.O.) ... 1.0
e) Ethanol ... 6.0
f) Perfume ... appropriate amount
g) Preservatives / Antioxidants ...
h) Purified water: the remainder Manufacturing method a), b), c), d), h) are mixed uniformly. Mix e) -g) uniformly and add to a), b), c), d), h) mixture.

(10) Lotion (wt%)
a) Snow tea extract ... 3.0
b) Mukuge extract ... 1.0
c) 1,3-Butylene glycol ・ ・ ・ 8.0
d) Polyoxyethylene sorbitan monolaurate (20E.O.) ... 1.0
e) Ethanol ... 6.0
f) Perfume ... appropriate amount
g) Preservatives / Antioxidants ...
h) Purified water: Remaining manufacturing method a), b), c), d), h) are mixed uniformly. Mix e) -g) uniformly and add to a), b), c), d), h) mixture.

(11) Lotion (wt%)
a) Snow tea extract ... 3.0
b) Azalea extract ... 1.0
c) Rose extract ... 1.0
d) 1,3-Butylene glycol ・ ・ ・ 8.0
e) Polyoxyethylene sorbitan monolaurate (20E.O.) ... 1.0
f) Ethanol ... 6.0
g) Perfume ... appropriate amount
h) Preservatives / Antioxidants ...
i) Purified water: Remainder manufacturing method a), b), c), d), e), i) are mixed uniformly. Mix f) to h) uniformly and add to a), b), c), d), e), i) mixture.

(12) Lotion (wt%)
a) Snow tea extract ... 3.0
b) Yoshino cherry extract ... 1.0
c) Naniwaibara extract ... 1.0
d) Mukuge extract ... 1.0
e) 1,3-Butylene glycol ・ ・ ・ 8.0
f) Polyoxyethylene sorbitan monolaurate (20E.O.) ... 1.0
g) Ethanol ... 6.0
h) Perfume
i) Preservatives / Antioxidants ...
j) Purified water: the rest of the manufacturing method a), b), c), d), e), f), j) are mixed uniformly. g) to i) are mixed uniformly and added to a), b), c), d), e), f), j) mixture.

(13) Face wash (wt%)
a) Snow tea extract ... 0.1
b) Yoshino cherry extract ... 0.1
c) Talc ... remainder
d) Cellulose ... 20.0
e) Potassium myristate ... 30.0
f) Sodium lauryl phosphate ... 10.0
g) Perfume ... appropriate amount
h) Preservatives: Appropriate amount of production method a) to h) are mixed, stirred and dispersed well to make uniform.

(14) Ointment (wt%)

a) Snow tea extract ... 0.1

b) Yoshino cherry extract ... 0.1

c) Triethanolamine ... 2.0

d) Glycerin ... 5.0

e) Purified water: balance

f) Cetanol ... 4.0

g) Preservatives: appropriate amount
A) to g) are heated and mixed, stirred well, dispersed and evenly cooled.

Claims (1)

Snow tea extract, Prunus plant extract, rhododendron (R hodod)
whitening cosmetics characterized by containing one or more ingredients selected from endron) genus plant extract, hibiscus genus plant extract, rose genus plant extract .