JP5017103B2 - 薬剤共結晶組成物および関連した使用方法 - Google Patents
薬剤共結晶組成物および関連した使用方法 Download PDFInfo
- Publication number
- JP5017103B2 JP5017103B2 JP2007516812A JP2007516812A JP5017103B2 JP 5017103 B2 JP5017103 B2 JP 5017103B2 JP 2007516812 A JP2007516812 A JP 2007516812A JP 2007516812 A JP2007516812 A JP 2007516812A JP 5017103 B2 JP5017103 B2 JP 5017103B2
- Authority
- JP
- Japan
- Prior art keywords
- crystal
- acid
- carbamazepine
- degrees
- angstrom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58066104P | 2004-06-17 | 2004-06-17 | |
US60/580,661 | 2004-06-17 | ||
US58580804P | 2004-07-06 | 2004-07-06 | |
US60/585,808 | 2004-07-06 | ||
US62148504P | 2004-10-22 | 2004-10-22 | |
US60/621,485 | 2004-10-22 | ||
US62870104P | 2004-11-17 | 2004-11-17 | |
US60/628,701 | 2004-11-17 | ||
PCT/US2005/021662 WO2006007448A2 (en) | 2004-06-17 | 2005-06-16 | Pharmaceutical co-crystal compositions and related methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008503495A JP2008503495A (ja) | 2008-02-07 |
JP5017103B2 true JP5017103B2 (ja) | 2012-09-05 |
Family
ID=35784343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007516812A Expired - Fee Related JP5017103B2 (ja) | 2004-06-17 | 2005-06-16 | 薬剤共結晶組成物および関連した使用方法 |
Country Status (4)
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003213719A1 (en) * | 2002-03-01 | 2003-09-16 | Regents Of The University Of Michigan | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
US20080319068A1 (en) * | 2005-04-27 | 2008-12-25 | Transform Pharmaceuticals, Inc. | Novel Polymorph of Acetylsalicylic Acid, and Methods of Making and Using the Same |
JP5436864B2 (ja) * | 2006-02-27 | 2014-03-05 | バーテックス ファーマシューティカルズ インコーポレイテッド | Vx−950を含む共結晶体およびそれを含む医薬組成物 |
US20080146772A1 (en) * | 2006-11-02 | 2008-06-19 | University Of South Florida | Materials and methods for co-crystal controlled solid-state synthesis of imides and imines |
TW200901889A (en) | 2007-02-09 | 2009-01-16 | Basf Se | Crystalline complexes of agriculturally active organic compounds |
ES2379905T3 (es) * | 2007-02-27 | 2012-05-04 | Vertex Pharmceuticals Incorporated | Co-cristales y composiciones farmacéuticas que los comprenden |
CA2680351A1 (en) * | 2007-03-23 | 2008-10-02 | Syngenta Limited | Co-crystals of propiconazole |
GB0706044D0 (en) * | 2007-03-28 | 2007-05-09 | Syngenta Ltd | C0-Crystals |
WO2008153938A2 (en) * | 2007-06-06 | 2008-12-18 | University Of South Florida | Epigallocatechin-3-gallate crystal compositions |
US20100204204A1 (en) | 2007-06-06 | 2010-08-12 | University Of South Florida | Nutraceutical co-crystal compositions |
DE102007030695A1 (de) * | 2007-07-01 | 2009-01-08 | Sciconcept Gmbh | Co-Kristalle aus Harnstoff mit Amid- und/oder Harnstoffderivaten |
CL2008002549A1 (es) * | 2007-08-30 | 2010-09-03 | Vertex Pharma | Cocristal que comprende vx-950 y un formador de cocristal seleccionado de acido 3-metoxi-4hidroxibenzoico,acido 2,4-dihidroxibenzoico y acido 2,5-dihidroxibenzoico; metodo de preparacion; composicion farmaceutica que comprende el cocristal, util como agente antiviral en el tratamiento del hcv. |
GB0813709D0 (en) * | 2008-07-26 | 2008-09-03 | Univ Dundee | Method and product |
WO2010020856A2 (en) * | 2008-08-19 | 2010-02-25 | Adcock Ingram Healthcare (Pty) Limited | Rate modulated delivery of drugs from a composite delivery system |
WO2010027921A1 (en) * | 2008-09-03 | 2010-03-11 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical formulations comprising the same |
EP2373326B1 (en) * | 2008-12-11 | 2016-03-09 | Axcentua Pharmaceutucals AB | Crystalline forms of genistein |
JP6074142B2 (ja) * | 2009-02-26 | 2017-02-01 | タール ファーマシューティカルズ,インコーポレイテッド | 医薬化合物の結晶化 |
US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
WO2011036676A2 (en) * | 2009-09-23 | 2011-03-31 | Ashwini Nangia | Stable cocrystals of temozolomide |
KR20120115492A (ko) * | 2009-11-06 | 2012-10-18 | 바스프 에스이 | 4―히드록시 벤조산 및 선택된 살충제의 결정질 복합체 |
WO2011115069A1 (ja) * | 2010-03-19 | 2011-09-22 | 第一三共株式会社 | 結晶の網羅的探索 |
US20120115799A1 (en) | 2010-05-11 | 2012-05-10 | Wenhua Wang | Pharmaceutical formulations |
SG10201507035UA (en) * | 2010-06-03 | 2015-10-29 | Salix Pharmaceuticals Ltd | New forms of rifaximin and uses thereof |
UA109290C2 (uk) | 2010-10-07 | 2015-08-10 | Спільні кристали і солі інгібіторів ccr3 | |
EP2688575B1 (en) * | 2011-03-24 | 2016-03-23 | University of South Florida | Lithium compositions |
CN103288724A (zh) * | 2013-05-31 | 2013-09-11 | 天津大学 | 一种氟尼辛与卡马西平共晶及其制备方法 |
US20150080567A1 (en) | 2013-09-04 | 2015-03-19 | Nalas Engineering Services Inc. | Method to Produce and Scale-Up Cocrystals and Salts Via Resonant Acoustic Mixing |
GB201411802D0 (en) * | 2014-07-02 | 2014-08-13 | Univ Bradford | Effervescent compositions |
KR101658870B1 (ko) * | 2014-07-18 | 2016-09-22 | 제이더블유중외제약 주식회사 | 테노포비어 디소프록실의 신규염 |
US10226426B2 (en) | 2015-03-02 | 2019-03-12 | Takeda Pharmaceutical Company Limited | Suspension containing nano-cocrystal and manufacturing method |
TWI736635B (zh) | 2016-06-13 | 2021-08-21 | 心悅生醫股份有限公司 | 苯甲酸鋰之共晶及其用途 |
CA3027297A1 (en) | 2016-06-13 | 2017-12-21 | Syneurx International (Taiwan) Corp. | Co-crystals of sodium benzoate and uses thereof |
US10703760B2 (en) * | 2016-08-19 | 2020-07-07 | Celgene International Ii Sàrl | Morphic forms of marizomib and uses thereof |
US11052091B2 (en) | 2016-12-21 | 2021-07-06 | Ono Pharmaceutical Co., Ltd. | BRK inhibitory compound |
US20200000816A1 (en) | 2017-02-08 | 2020-01-02 | Ono Pharmaceutical Co., Ltd. | Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof |
ES2954717T3 (es) | 2017-05-22 | 2023-11-23 | Ono Pharmaceutical Co | Antagonista de EP4 |
BR112020017036A2 (pt) | 2018-02-22 | 2020-12-15 | Ono Pharmaceutical Co., Ltd. | Compostos com atividade agonista do receptor s1p5 |
JP7021709B2 (ja) | 2018-09-20 | 2022-02-17 | 小野薬品工業株式会社 | Dpアンタゴニスト |
TW202028212A (zh) | 2018-10-11 | 2020-08-01 | 日商小野藥品工業股份有限公司 | Sting促效化合物 |
CN109796393A (zh) * | 2019-01-25 | 2019-05-24 | 云南开放大学 | 一种吡拉西坦共晶及其制备方法 |
TW202114985A (zh) | 2019-06-28 | 2021-04-16 | 日商小野藥品工業股份有限公司 | Ep拮抗劑 |
JP2021054781A (ja) * | 2019-09-26 | 2021-04-08 | デボン エルエス,リミテッド | 共結晶形エフィナコナゾール、及びその製造方法 |
EP4066895A1 (en) | 2019-11-29 | 2022-10-05 | ONO Pharmaceutical Co., Ltd. | Compound having lysophosphatidic acid receptor agonistic activity and pharmaceutical use of said compound |
EP4134098A4 (en) | 2020-04-10 | 2024-05-15 | Ono Pharmaceutical Co | CANCER THERAPY METHODS |
JPWO2021205631A1 (US07803786-20100928-C00012.png) | 2020-04-10 | 2021-10-14 | ||
MX2022013692A (es) | 2020-05-07 | 2022-11-30 | Ono Pharmaceutical Co | Compuesto que tiene actividad inhibidora de desmetilasa 5 (kdm5) y uso farmaceutico del mismo. |
KR20230107228A (ko) | 2020-11-13 | 2023-07-14 | 오노 야꾸힝 고교 가부시키가이샤 | Ep4 길항약과 면역 체크포인트 저해 물질의 병용에 의한 암 치료 |
BR112023019657A2 (pt) | 2021-04-01 | 2023-10-31 | Ono Pharmaceutical Co | Antagonista de abhd6 |
CN113845438B (zh) * | 2021-10-12 | 2023-02-21 | 河北大学 | 一种对乙酰氨基酚-吡拉西坦药物共晶及其制备方法 |
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DE69822208T2 (de) | 1997-12-29 | 2005-04-28 | Alza Corp., Mountain View | Osmotisches verabreichungssystem mit stöpselrückhaltemechanismus |
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US6342249B1 (en) | 1998-12-23 | 2002-01-29 | Alza Corporation | Controlled release liquid active agent formulation dosage forms |
WO2004078163A2 (en) * | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
AU2003213719A1 (en) * | 2002-03-01 | 2003-09-16 | Regents Of The University Of Michigan | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
EP1511490A4 (en) * | 2002-05-31 | 2009-03-11 | Transform Pharmaceuticals Inc | NOVEL CONAZOLE CRYSTALLINE FORMS AND RELATED METHODS, PHARMACEUTICAL COMPOSITIONS AND METHODS |
CA2514092C (en) * | 2003-01-21 | 2013-03-19 | S.S.C.I., Inc. | Novel cocrystallization of hydrochloric acid salt of an active agent |
-
2005
- 2005-06-16 JP JP2007516812A patent/JP5017103B2/ja not_active Expired - Fee Related
- 2005-06-16 WO PCT/US2005/021662 patent/WO2006007448A2/en active Application Filing
- 2005-06-16 EP EP05762769A patent/EP1765379A4/en not_active Withdrawn
- 2005-06-16 US US11/629,807 patent/US7803786B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1765379A4 (en) | 2009-05-27 |
US7803786B2 (en) | 2010-09-28 |
WO2006007448A3 (en) | 2007-10-25 |
US20070299033A1 (en) | 2007-12-27 |
EP1765379A2 (en) | 2007-03-28 |
WO2006007448A2 (en) | 2006-01-19 |
JP2008503495A (ja) | 2008-02-07 |
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