JP5006802B2 - 上皮由来の癌診断および予後診断のためのバイオマーカーとしてのCyr61 - Google Patents
上皮由来の癌診断および予後診断のためのバイオマーカーとしてのCyr61Info
- Publication number
- JP5006802B2 JP5006802B2 JP2007556362A JP2007556362A JP5006802B2 JP 5006802 B2 JP5006802 B2 JP 5006802B2 JP 2007556362 A JP2007556362 A JP 2007556362A JP 2007556362 A JP2007556362 A JP 2007556362A JP 5006802 B2 JP5006802 B2 JP 5006802B2
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- cyr61
- antibody
- level
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65411105P | 2005-02-18 | 2005-02-18 | |
| US60/654,111 | 2005-02-18 | ||
| PCT/US2006/005812 WO2006089212A2 (en) | 2005-02-18 | 2006-02-17 | Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008530582A JP2008530582A (ja) | 2008-08-07 |
| JP2008530582A5 JP2008530582A5 (https=) | 2009-04-16 |
| JP5006802B2 true JP5006802B2 (ja) | 2012-08-22 |
Family
ID=36917123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007556362A Expired - Fee Related JP5006802B2 (ja) | 2005-02-18 | 2006-02-17 | 上皮由来の癌診断および予後診断のためのバイオマーカーとしてのCyr61 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7858324B2 (https=) |
| EP (1) | EP1849002A4 (https=) |
| JP (1) | JP5006802B2 (https=) |
| CN (1) | CN101120252A (https=) |
| AU (1) | AU2006214105A1 (https=) |
| CA (1) | CA2598217A1 (https=) |
| WO (1) | WO2006089212A2 (https=) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| WO2006089212A2 (en) * | 2005-02-18 | 2006-08-24 | Children's Medical Center Corporation | Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin |
| WO2007081385A2 (en) | 2006-01-11 | 2007-07-19 | Raindance Technologies, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| EP2530167A1 (en) | 2006-05-11 | 2012-12-05 | Raindance Technologies, Inc. | Microfluidic Devices |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| EP2077912B1 (en) | 2006-08-07 | 2019-03-27 | The President and Fellows of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| WO2008097559A2 (en) | 2007-02-06 | 2008-08-14 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| US8455189B2 (en) * | 2007-03-29 | 2013-06-04 | Jeffrey W. Allard | Use of HE4 for assessment of breast cancers |
| US8592221B2 (en) | 2007-04-19 | 2013-11-26 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| EP4047367A1 (en) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Method for detecting target analytes with droplet libraries |
| MX2011001445A (es) * | 2008-08-05 | 2011-04-05 | Toray Industries | Metodo para detectar cancer. |
| BRPI0911926A2 (pt) | 2008-08-05 | 2020-08-18 | Toray Industries, Inc | composições farmacêuticas, anticorpos e usos de um anticorpo ou um fragmento do mesmo. |
| CN101747435B (zh) * | 2008-12-18 | 2013-06-19 | 上海市免疫学研究所 | 一种中和cyr61的单克隆抗体(杂交瘤)及其应用 |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| EP2273272A1 (en) | 2009-07-06 | 2011-01-12 | Stichting Katholieke Universiteit | Method for predicting the outcome of chemotherapy in ovarian cancer |
| US10520500B2 (en) | 2009-10-09 | 2019-12-31 | Abdeslam El Harrak | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| US10837883B2 (en) | 2009-12-23 | 2020-11-17 | Bio-Rad Laboratories, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
| DK2532680T3 (da) | 2010-02-04 | 2015-07-20 | Toray Industries | Medicinsk sammensætning til behandling og/eller forebyggelse af cancer |
| US9115200B2 (en) | 2010-02-04 | 2015-08-25 | Toray Industries, Inc. | Pharmaceutical composition for treating cancer using a monoclonal antibody having immunological reactivity with CAPRIN-1 |
| DK2532366T3 (da) | 2010-02-04 | 2017-01-02 | Toray Industries | Farmaceutisk sammensætning til behandling og/eller forebyggelse af cancer |
| HUE040012T2 (hu) | 2010-02-04 | 2019-02-28 | Toray Industries | Gyógyászati ágens rák kezelésére és/vagy megelõzésére |
| CA2788545C (en) | 2010-02-04 | 2019-03-26 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
| RU2603742C2 (ru) | 2010-02-04 | 2016-11-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP4484577A3 (en) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US9562897B2 (en) | 2010-09-30 | 2017-02-07 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| EP3412778A1 (en) | 2011-02-11 | 2018-12-12 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| WO2012112804A1 (en) | 2011-02-18 | 2012-08-23 | Raindance Technoligies, Inc. | Compositions and methods for molecular labeling |
| EP3216872B1 (en) | 2011-06-02 | 2020-04-01 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| WO2012174498A2 (en) * | 2011-06-16 | 2012-12-20 | Pitari Giovanni M | Biomarkers for epithelial cancer diagnosis and treatment |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| RU2595400C2 (ru) | 2011-08-04 | 2016-08-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли |
| PT2740796T (pt) | 2011-08-04 | 2017-07-26 | Toray Industries | Composição farmacêutica para o tratamento e/ou profilaxia de cancro |
| EP2740794B1 (en) | 2011-08-04 | 2018-04-04 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| US9181348B2 (en) | 2011-08-04 | 2015-11-10 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| PL2740793T3 (pl) | 2011-08-04 | 2018-04-30 | Toray Industries, Inc. | Kompozycja leku do leczenia i/lub zapobiegania nowotworowi |
| PT2740489T (pt) | 2011-08-04 | 2017-01-10 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção do cancro pancreático |
| ES2629061T3 (es) | 2011-08-04 | 2017-08-07 | Toray Industries, Inc. | Método para la detección de cáncer pancreático |
| WO2013120089A1 (en) | 2012-02-10 | 2013-08-15 | Raindance Technologies, Inc. | Molecular diagnostic screening assay |
| US9260513B2 (en) | 2012-02-21 | 2016-02-16 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| ES2739612T3 (es) | 2012-02-21 | 2020-02-03 | Toray Industries | Composición farmacéutica para el tratamiento de cáncer |
| WO2013125654A1 (ja) | 2012-02-21 | 2013-08-29 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
| BR112014021103A2 (pt) | 2012-02-21 | 2019-10-15 | Toray Industries, Inc | Anticorpo, composição farmacêutica, droga de combinação, dna, método de tratamento e uso de anticorpo |
| JP6107654B2 (ja) | 2012-03-30 | 2017-04-05 | 東レ株式会社 | 肝臓癌の治療及び/又は予防用医薬組成物 |
| WO2013147176A1 (ja) | 2012-03-30 | 2013-10-03 | 東レ株式会社 | 胆嚢癌の治療及び/又は予防用医薬組成物 |
| EP2844768B1 (en) | 2012-04-30 | 2019-03-13 | Raindance Technologies, Inc. | Digital analyte analysis |
| PL2876447T3 (pl) | 2012-07-19 | 2020-05-18 | Toray Industries, Inc. | Sposób wykrywania nowotworu |
| MX357292B (es) | 2012-07-19 | 2018-07-04 | Toray Industries | Método para detectar cáncer. |
| WO2014172288A2 (en) | 2013-04-19 | 2014-10-23 | Raindance Technologies, Inc. | Digital analyte analysis |
| AU2014303375B2 (en) | 2013-08-09 | 2019-07-04 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| CN105396136B (zh) * | 2015-11-23 | 2018-10-30 | 上海交通大学医学院附属第九人民医院 | CCN1(Cyr61)在治疗皮肤损伤及皮肤萎缩相关疾病中的应用 |
| CN107422125A (zh) * | 2016-05-23 | 2017-12-01 | 中国医学科学院肿瘤医院 | 与肌层浸润性膀胱癌相关的尿液蛋白质标志物 |
| EP3364190A1 (en) * | 2017-02-20 | 2018-08-22 | Panka Cancer Research AG | Method of detecting cancer or cancer cells |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| CN108752454B (zh) * | 2018-06-19 | 2021-07-20 | 中山大学孙逸仙纪念医院 | 一种人CYR61蛋白Ser188位点磷酸化抗原、抗体及其制备方法和应用 |
| CN111426835A (zh) * | 2019-01-10 | 2020-07-17 | 北京师范大学 | 肝转移癌相关的尿液蛋白标记物的筛选及其用途 |
| CN113777315A (zh) * | 2020-06-09 | 2021-12-10 | 首都医科大学附属北京世纪坛医院 | 尿液泛素样蛋白isg15及其多肽片段在烧伤中的应用 |
| CN112147337B (zh) * | 2020-08-19 | 2024-05-28 | 德赛诊断系统(上海)有限公司 | 一种富含半胱氨酸蛋白61高敏化学发光检测试剂盒及其制备和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
| US6355623B2 (en) * | 1998-09-24 | 2002-03-12 | Hopital-Sainte-Justine | Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage |
| WO2000052204A2 (en) * | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Gene expression in bladder tumors |
| US20020052308A1 (en) * | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| AU2001271365A1 (en) | 2000-06-21 | 2002-01-02 | Wyeth | Cyr61 as a target for treatment and diagnosis of breast cancer |
| CA2423413A1 (en) * | 2000-09-29 | 2002-04-04 | Wyeth | Use of cyr61 in the treatment and diagnosis of human uterine leiomyomas |
| US20040086504A1 (en) * | 2001-06-21 | 2004-05-06 | Deepak Sampath | Cyr61 as a target for treatment and diagnosis of breast cancer |
| WO2003009814A2 (en) * | 2001-07-25 | 2003-02-06 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| US20030113816A1 (en) | 2001-09-18 | 2003-06-19 | Weitz Stephen L. | Methods of assaying connective tissue growth factor |
| JP2003177126A (ja) * | 2001-12-13 | 2003-06-27 | Kenichi Katsube | Ccnファミリー蛋白質活性制御剤のスクリーニング方法 |
| US20040241653A1 (en) * | 2001-12-31 | 2004-12-02 | Elena Feinstein | Methods for identifying marker genes for cancer |
| DE602004022150D1 (de) * | 2003-03-27 | 2009-09-03 | Childrens Hosp Medical Center | Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung |
| JP2004315480A (ja) * | 2003-04-21 | 2004-11-11 | Yoshiyuki Kakehi | 前立腺疾患治療用医薬組成物 |
| WO2006089212A2 (en) * | 2005-02-18 | 2006-08-24 | Children's Medical Center Corporation | Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin |
-
2006
- 2006-02-17 WO PCT/US2006/005812 patent/WO2006089212A2/en not_active Ceased
- 2006-02-17 EP EP06735465A patent/EP1849002A4/en not_active Ceased
- 2006-02-17 US US11/815,831 patent/US7858324B2/en active Active
- 2006-02-17 CA CA002598217A patent/CA2598217A1/en not_active Abandoned
- 2006-02-17 CN CNA2006800051581A patent/CN101120252A/zh active Pending
- 2006-02-17 JP JP2007556362A patent/JP5006802B2/ja not_active Expired - Fee Related
- 2006-02-17 AU AU2006214105A patent/AU2006214105A1/en not_active Abandoned
-
2010
- 2010-12-23 US US12/977,348 patent/US20110189700A1/en not_active Abandoned
-
2016
- 2016-08-29 US US15/249,829 patent/US20170205419A1/en not_active Abandoned
-
2018
- 2018-06-26 US US16/018,254 patent/US20190154693A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006214105A1 (en) | 2006-08-24 |
| WO2006089212A3 (en) | 2007-01-11 |
| WO2006089212A2 (en) | 2006-08-24 |
| EP1849002A2 (en) | 2007-10-31 |
| US20110189700A1 (en) | 2011-08-04 |
| US7858324B2 (en) | 2010-12-28 |
| JP2008530582A (ja) | 2008-08-07 |
| US20170205419A1 (en) | 2017-07-20 |
| US20080286811A1 (en) | 2008-11-20 |
| CA2598217A1 (en) | 2006-08-24 |
| US20190154693A1 (en) | 2019-05-23 |
| CN101120252A (zh) | 2008-02-06 |
| EP1849002A4 (en) | 2008-08-20 |
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