JP4968974B2 - 血液製剤からソラレンを除去するための方法およびデバイス - Google Patents
血液製剤からソラレンを除去するための方法およびデバイス Download PDFInfo
- Publication number
- JP4968974B2 JP4968974B2 JP50204597A JP50204597A JP4968974B2 JP 4968974 B2 JP4968974 B2 JP 4968974B2 JP 50204597 A JP50204597 A JP 50204597A JP 50204597 A JP50204597 A JP 50204597A JP 4968974 B2 JP4968974 B2 JP 4968974B2
- Authority
- JP
- Japan
- Prior art keywords
- blood
- psoralen
- resin
- platelet
- adsorbent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 0 Cc1c(COCC*)[o]c2c1C1C(C)=CC(O)OC1=C2C Chemical compound Cc1c(COCC*)[o]c2c1C1C(C)=CC(O)OC1=C2C 0.000 description 2
- MRNJPTRJTKTMJZ-UHFFFAOYSA-N CC(CCC1)C1C1OC1 Chemical compound CC(CCC1)C1C1OC1 MRNJPTRJTKTMJZ-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/12—Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
- A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
- A61L2/08—Radiation
- A61L2/081—Gamma radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
- B32B5/02—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
- B32B5/028—Net structure, e.g. spaced apart filaments bonded at the crossing points
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2103/00—Materials or objects being the target of disinfection or sterilisation
- A61L2103/05—Living organisms or biological materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/80—Medical packaging
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Anesthesiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- External Artificial Organs (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48492695A | 1995-06-07 | 1995-06-07 | |
| US08/484,926 | 1995-06-07 | ||
| US66091096A | 1996-06-07 | 1996-06-07 | |
| US08/660,908 | 1996-06-07 | ||
| US08/659,249 | 1996-06-07 | ||
| PCT/US1996/009846 WO1996040857A1 (en) | 1995-06-07 | 1996-06-07 | Methods and devices for the removal of psoralens from blood products |
| US08/659,249 US6544727B1 (en) | 1995-06-07 | 1996-06-07 | Methods and devices for the removal of psoralens from blood products |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008240092A Division JP2009051846A (ja) | 1995-06-07 | 2008-09-18 | 血液製剤からソラレンを除去するための方法およびデバイス |
| JP2009055780A Division JP2009132728A (ja) | 1995-06-07 | 2009-03-09 | 血液製剤からソラレンを除去するための方法およびデバイス |
| JP2011284346A Division JP2012067126A (ja) | 1995-06-07 | 2011-12-26 | 血液製剤からソラレンを除去するための方法およびデバイス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002509518A JP2002509518A (ja) | 2002-03-26 |
| JP2002509518A5 JP2002509518A5 (https=) | 2009-04-30 |
| JP4968974B2 true JP4968974B2 (ja) | 2012-07-04 |
Family
ID=29740870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50204597A Expired - Lifetime JP4968974B2 (ja) | 1995-06-07 | 1996-06-07 | 血液製剤からソラレンを除去するための方法およびデバイス |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0840781B1 (https=) |
| JP (1) | JP4968974B2 (https=) |
| AT (1) | ATE451445T1 (https=) |
| AU (1) | AU6267796A (https=) |
| CA (1) | CA2221605C (https=) |
| DE (1) | DE69638094D1 (https=) |
| ES (1) | ES2337852T3 (https=) |
| WO (1) | WO1996040857A1 (https=) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996039818A1 (en) * | 1995-06-07 | 1996-12-19 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| JP2009051846A (ja) * | 1995-06-07 | 2009-03-12 | Cerus Corp | 血液製剤からソラレンを除去するための方法およびデバイス |
| DE19544297A1 (de) * | 1995-11-28 | 1997-06-05 | Behringwerke Ag | Verfahren zur Entfernung von aromatischen Verbindungen aus produkthaltigen Lösungen |
| AU714882B2 (en) * | 1996-04-09 | 2000-01-13 | Therakos, Inc. | Method for removal of psoralens from biological fluids |
| US20010018179A1 (en) | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
| US6514987B1 (en) | 1997-01-06 | 2003-02-04 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| ES2434319T3 (es) * | 1997-01-06 | 2013-12-16 | Cerus Corporation | Sistema y método para la reducción de los compuestos orgánicos pequeños de los hemoderivados |
| US20010009756A1 (en) | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
| US6093725A (en) * | 1997-01-06 | 2000-07-25 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| US7611831B2 (en) | 1998-01-06 | 2009-11-03 | Cerus Corporation | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix |
| JP4643004B2 (ja) | 1998-01-06 | 2011-03-02 | シーラス コーポレイション | 生体材料中の病原体不活性化剤をクエンチするための方法 |
| US6617100B2 (en) * | 1998-09-25 | 2003-09-09 | V.I. Technologies, Inc. | Solid phase quenching systems |
| US6403359B1 (en) * | 1998-09-25 | 2002-06-11 | V. I. TECHNOLOGIES, Inc. | Solid phase quenching systems |
| US6565802B1 (en) | 1999-06-03 | 2003-05-20 | Baxter International Inc. | Apparatus, systems and methods for processing and treating a biological fluid with light |
| US6364864B1 (en) | 1999-06-03 | 2002-04-02 | Baxter International Inc. | Plastic containers having inner pouches and methods for making such containers |
| US7445756B2 (en) | 1999-06-03 | 2008-11-04 | Fenwal, Inc. | Fluid processing sets and organizers for the same |
| US7068361B2 (en) | 1999-06-03 | 2006-06-27 | Baxter International | Apparatus, systems and methods for processing and treating a biological fluid with light |
| US7025877B1 (en) | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
| JP5112060B2 (ja) * | 2004-06-29 | 2013-01-09 | リライアンス ライフ サイエンシーズ プライベイト リミテッド | ウイルス安全性生物学的流体の調製のための方法 |
| PL1838355T3 (pl) | 2004-10-29 | 2014-01-31 | Cerus Corp | Ulepszone sposoby wygaszania dla procesu inaktywacji czerwonych krwinek |
| DK1960016T3 (en) | 2005-12-13 | 2017-01-09 | Exthera Medical Corp | Method for extracorporeal removal by a pathogenic MI-KROBE, an inflammatory cell or inflammatory protein from the blood. |
| WO2007082111A1 (en) | 2006-01-05 | 2007-07-19 | Saint-Gobain Performance Plastics Corporation | Annular seal and pump including same |
| WO2007082110A1 (en) | 2006-01-05 | 2007-07-19 | Saint-Gobain Performance Plastics Corporation | Composite material and seals formed thereof |
| EA023596B1 (ru) | 2008-04-09 | 2016-06-30 | Сирус Корпорейшн | Способы обработки композиции эритроцитов для инактивации патогена |
| DE202008012267U1 (de) * | 2008-09-16 | 2009-02-05 | KBD Gesellschaft für Unternehmensberatung, Marketing und Vertrieb mbH i. Gr. | Vorrichtung zum visuellen Erkennen der Verteilung von lumineszierenden Substanzen |
| WO2010074831A1 (en) | 2008-12-16 | 2010-07-01 | Dow Corning Corporation | Preparation of siloxanes |
| CN102245943A (zh) | 2008-12-24 | 2011-11-16 | 美国圣戈班性能塑料公司 | 用于高压泵应用的聚合物材料及其形成的密封件 |
| US11864553B2 (en) | 2009-10-23 | 2024-01-09 | Fenwal, Inc. | Methods and systems for providing red blood cell products with reduced plasma |
| EP2509604B1 (en) | 2009-12-01 | 2021-03-17 | ExThera Medical Corporation | Device for removing cytokines from blood with surface immobilized polysaccharides |
| WO2012112724A1 (en) | 2011-02-15 | 2012-08-23 | Exthera Medical, Llc | Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines |
| EP2861273B1 (en) | 2012-06-13 | 2017-08-23 | ExThera Medical Corporation | Use of heparin and carbohydrates to treat cancer |
| US9414752B2 (en) | 2012-11-09 | 2016-08-16 | Elwha Llc | Embolism deflector |
| US20140158604A1 (en) * | 2012-12-12 | 2014-06-12 | Jacques Chammas | Platelet Storage Container |
| MX376935B (es) | 2013-06-24 | 2025-03-07 | Exthera Medical Corp | Sistema de filtración de sangre que contiene substrato recubierto con manosa. |
| JP2016529885A (ja) | 2013-07-12 | 2016-09-29 | イー・エム・デイー・ミリポア・コーポレイシヨン | 活性炭を使用して標的タンパク質を含む試料からのウイルス除去を決定する方法 |
| CA2928866C (en) | 2013-11-08 | 2021-11-09 | Exthera Medical Corporation | Methods for diagnosing infectious diseases using adsorption media |
| AU2015250107A1 (en) | 2014-04-24 | 2016-11-17 | Exthera Medical Corporation | Method for removing bacteria from blood using high flow rate |
| US10842818B2 (en) | 2014-07-23 | 2020-11-24 | Cerus Corporation | Methods for preparing platelet products |
| CA2959975A1 (en) * | 2014-09-22 | 2016-03-31 | Exthera Medical Corporation | Wearable hemoperfusion device |
| EP3204426B1 (en) | 2014-10-10 | 2020-11-25 | Cerus Corporation | Compositions for use in treating viral hemorrhagic fever |
| SG10202004071UA (en) | 2015-06-26 | 2020-05-28 | Cerus Corp | Cryoprecipitate compositions and methods of preparation thereof |
| US20170028121A1 (en) * | 2015-07-31 | 2017-02-02 | Fenwal, Inc. | Irradiation device for biological fluids |
| EP3364986B1 (en) | 2015-10-23 | 2023-12-13 | Cerus Corporation | Pathogen-inactivated cryo-poor plasma and methods of use thereof |
| IL260393B2 (en) | 2016-01-07 | 2024-06-01 | Cerus Corp | Systems and methods for preparation of platelets |
| US11911551B2 (en) | 2016-03-02 | 2024-02-27 | Exthera Medical Corporation | Method for treating drug intoxication |
| US10786615B2 (en) | 2016-03-02 | 2020-09-29 | Exthera Medical Corporation | Method for treating drug intoxication |
| US11235090B2 (en) | 2017-03-03 | 2022-02-01 | Cerus Corporation | Kits and methods for preparing pathogen-inactivated platelet compositions |
| SG11202002438TA (en) | 2017-09-20 | 2020-04-29 | Cerus Corp | Compositions and methods for pathogen inactivation of platelets |
| CN116571191A (zh) | 2017-12-29 | 2023-08-11 | 塞鲁斯公司 | 用于处理生物流体的系统和方法 |
| WO2020231830A1 (en) | 2019-05-16 | 2020-11-19 | Exthera Medical Corporation | Method for modulating endothelial glycocalyx structure |
| JP7576052B2 (ja) | 2019-06-22 | 2024-10-30 | シーラス コーポレイション | 生物学的流体処理システム |
| US12514944B2 (en) | 2019-06-22 | 2026-01-06 | Cerus Corporation | Systems and methods for implementing treatment of biological fluids |
| KR20220039716A (ko) | 2019-06-28 | 2022-03-29 | 세루스 코포레이션 | 생물학적 유체 처리 장치를 구현하기 위한 시스템 및 방법 |
| WO2025264876A1 (en) | 2024-06-20 | 2025-12-26 | Cerus Corporation | Systems and methods for pathogen inactivation of blood products |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE756082A (fr) * | 1969-09-12 | 1971-03-11 | I Elementoorganiche Kih Soedin | Squelettes macroreticulaires de polystyrene pour resines echangeuses d'ions et leur procede de preparation ( |
| US4748120A (en) * | 1983-05-02 | 1988-05-31 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
| DE3819000A1 (de) * | 1988-06-03 | 1989-12-14 | Hasso Von Bluecher | Beutel in der art eines teebeutels zur beseitigung von schadstoffen |
| US5094960A (en) * | 1988-10-07 | 1992-03-10 | New York Blood Center, Inc. | Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography |
| US5418130A (en) * | 1990-04-16 | 1995-05-23 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
| US5176634A (en) * | 1990-08-02 | 1993-01-05 | Mcgaw, Inc. | Flexible multiple compartment drug container |
| US5209347A (en) * | 1990-12-05 | 1993-05-11 | Clintec Nutrition Company | Internal tear seal dual bag |
| US5128048A (en) * | 1991-05-22 | 1992-07-07 | Baxter International Inc. | Systems and methods for removing undesired matter from blood cells |
| KR960703167A (ko) * | 1993-06-23 | 1996-06-19 | 존 더블유. 아담슨 | 혈액내 바이러스 불활성화 시스템(system for viral inactivation of blood) |
| US5399719A (en) * | 1993-06-28 | 1995-03-21 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
| US6319662B1 (en) * | 1993-12-17 | 2001-11-20 | Baxter International Inc. | Method and apparatus for removing viral contaminants from a body fluid |
-
1996
- 1996-06-07 AU AU62677/96A patent/AU6267796A/en not_active Abandoned
- 1996-06-07 EP EP96921456A patent/EP0840781B1/en not_active Expired - Lifetime
- 1996-06-07 CA CA002221605A patent/CA2221605C/en not_active Expired - Fee Related
- 1996-06-07 ES ES96921456T patent/ES2337852T3/es not_active Expired - Lifetime
- 1996-06-07 JP JP50204597A patent/JP4968974B2/ja not_active Expired - Lifetime
- 1996-06-07 DE DE69638094T patent/DE69638094D1/de not_active Expired - Lifetime
- 1996-06-07 AT AT96921456T patent/ATE451445T1/de not_active IP Right Cessation
- 1996-06-07 WO PCT/US1996/009846 patent/WO1996040857A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0840781A1 (en) | 1998-05-13 |
| ATE451445T1 (de) | 2009-12-15 |
| ES2337852T3 (es) | 2010-04-29 |
| EP0840781A4 (en) | 2001-03-21 |
| EP0840781B1 (en) | 2009-12-09 |
| JP2002509518A (ja) | 2002-03-26 |
| CA2221605C (en) | 2005-10-18 |
| AU6267796A (en) | 1996-12-30 |
| DE69638094D1 (de) | 2010-01-21 |
| WO1996040857A1 (en) | 1996-12-19 |
| CA2221605A1 (en) | 1996-12-19 |
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