CA2221605C - Methods and devices for the removal of psoralens from blood products - Google Patents

Methods and devices for the removal of psoralens from blood products Download PDF

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Publication number
CA2221605C
CA2221605C CA002221605A CA2221605A CA2221605C CA 2221605 C CA2221605 C CA 2221605C CA 002221605 A CA002221605 A CA 002221605A CA 2221605 A CA2221605 A CA 2221605A CA 2221605 C CA2221605 C CA 2221605C
Authority
CA
Canada
Prior art keywords
psoralen
blood
resin
container
platelet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002221605A
Other languages
English (en)
French (fr)
Other versions
CA2221605A1 (en
Inventor
Derek J. Hei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cerus Corp
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Priority claimed from US08/659,249 external-priority patent/US6544727B1/en
Publication of CA2221605A1 publication Critical patent/CA2221605A1/en
Application granted granted Critical
Publication of CA2221605C publication Critical patent/CA2221605C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/12—Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/02—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
    • B32B5/028—Net structure, e.g. spaced apart filaments bonded at the crossing points
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00—Containers; Receptacles
    • B32B2439/80—Medical packaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • External Artificial Organs (AREA)
  • Compounds Of Unknown Constitution (AREA)
CA002221605A 1995-06-07 1996-06-07 Methods and devices for the removal of psoralens from blood products Expired - Fee Related CA2221605C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US48492695A 1995-06-07 1995-06-07
US08/484,926 1995-06-07
US66091096A 1996-06-07 1996-06-07
US08/659,249 1996-06-07
US08/660,910 1996-06-07
PCT/US1996/009846 WO1996040857A1 (en) 1995-06-07 1996-06-07 Methods and devices for the removal of psoralens from blood products
US08/659,249 US6544727B1 (en) 1995-06-07 1996-06-07 Methods and devices for the removal of psoralens from blood products

Publications (2)

Publication Number Publication Date
CA2221605A1 CA2221605A1 (en) 1996-12-19
CA2221605C true CA2221605C (en) 2005-10-18

Family

ID=29740870

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002221605A Expired - Fee Related CA2221605C (en) 1995-06-07 1996-06-07 Methods and devices for the removal of psoralens from blood products

Country Status (8)

Country Link
EP (1) EP0840781B1 (https=)
JP (1) JP4968974B2 (https=)
AT (1) ATE451445T1 (https=)
AU (1) AU6267796A (https=)
CA (1) CA2221605C (https=)
DE (1) DE69638094D1 (https=)
ES (1) ES2337852T3 (https=)
WO (1) WO1996040857A1 (https=)

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DE19544297A1 (de) * 1995-11-28 1997-06-05 Behringwerke Ag Verfahren zur Entfernung von aromatischen Verbindungen aus produkthaltigen Lösungen
AU714882B2 (en) * 1996-04-09 2000-01-13 Therakos, Inc. Method for removal of psoralens from biological fluids
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US6514987B1 (en) 1997-01-06 2003-02-04 Cerus Corporation Frangible compounds for pathogen inactivation
ES2434319T3 (es) * 1997-01-06 2013-12-16 Cerus Corporation Sistema y método para la reducción de los compuestos orgánicos pequeños de los hemoderivados
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US6093725A (en) * 1997-01-06 2000-07-25 Cerus Corporation Frangible compounds for pathogen inactivation
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
JP4643004B2 (ja) 1998-01-06 2011-03-02 シーラス コーポレイション 生体材料中の病原体不活性化剤をクエンチするための方法
US6617100B2 (en) * 1998-09-25 2003-09-09 V.I. Technologies, Inc. Solid phase quenching systems
US6403359B1 (en) * 1998-09-25 2002-06-11 V. I. TECHNOLOGIES, Inc. Solid phase quenching systems
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US6364864B1 (en) 1999-06-03 2002-04-02 Baxter International Inc. Plastic containers having inner pouches and methods for making such containers
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7025877B1 (en) 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
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PL1838355T3 (pl) 2004-10-29 2014-01-31 Cerus Corp Ulepszone sposoby wygaszania dla procesu inaktywacji czerwonych krwinek
DK1960016T3 (en) 2005-12-13 2017-01-09 Exthera Medical Corp Method for extracorporeal removal by a pathogenic MI-KROBE, an inflammatory cell or inflammatory protein from the blood.
WO2007082111A1 (en) 2006-01-05 2007-07-19 Saint-Gobain Performance Plastics Corporation Annular seal and pump including same
WO2007082110A1 (en) 2006-01-05 2007-07-19 Saint-Gobain Performance Plastics Corporation Composite material and seals formed thereof
EA023596B1 (ru) 2008-04-09 2016-06-30 Сирус Корпорейшн Способы обработки композиции эритроцитов для инактивации патогена
DE202008012267U1 (de) * 2008-09-16 2009-02-05 KBD Gesellschaft für Unternehmensberatung, Marketing und Vertrieb mbH i. Gr. Vorrichtung zum visuellen Erkennen der Verteilung von lumineszierenden Substanzen
WO2010074831A1 (en) 2008-12-16 2010-07-01 Dow Corning Corporation Preparation of siloxanes
CN102245943A (zh) 2008-12-24 2011-11-16 美国圣戈班性能塑料公司 用于高压泵应用的聚合物材料及其形成的密封件
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
EP2509604B1 (en) 2009-12-01 2021-03-17 ExThera Medical Corporation Device for removing cytokines from blood with surface immobilized polysaccharides
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
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Also Published As

Publication number Publication date
EP0840781A1 (en) 1998-05-13
JP4968974B2 (ja) 2012-07-04
ATE451445T1 (de) 2009-12-15
ES2337852T3 (es) 2010-04-29
EP0840781A4 (en) 2001-03-21
EP0840781B1 (en) 2009-12-09
JP2002509518A (ja) 2002-03-26
AU6267796A (en) 1996-12-30
DE69638094D1 (de) 2010-01-21
WO1996040857A1 (en) 1996-12-19
CA2221605A1 (en) 1996-12-19

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