JP4929352B2 - 注入可能なパラセタモール液剤 - Google Patents

注入可能なパラセタモール液剤 Download PDF

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Publication number
JP4929352B2
JP4929352B2 JP2009519998A JP2009519998A JP4929352B2 JP 4929352 B2 JP4929352 B2 JP 4929352B2 JP 2009519998 A JP2009519998 A JP 2009519998A JP 2009519998 A JP2009519998 A JP 2009519998A JP 4929352 B2 JP4929352 B2 JP 4929352B2
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JP
Japan
Prior art keywords
paracetamol
solution
aqueous
solutions
injectable
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Active
Application number
JP2009519998A
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English (en)
Japanese (ja)
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JP2009543851A5 (enExample
JP2009543851A (ja
Inventor
ムニョス，ファウスティノ ウエルタス
プラガロ，ラウル フェルナンデス
Original Assignee
スペイン ファルマ ソシエダ アノニマ
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Publication of JP2009543851A5 publication Critical patent/JP2009543851A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2009519998A 2006-07-18 2006-07-18 注入可能なパラセタモール液剤 Active JP4929352B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2006/070108 WO2008009756A1 (es) 2006-07-18 2006-07-18 Formulación líquida inyectable de paracetamol

Publications (3)

Publication Number Publication Date
JP2009543851A JP2009543851A (ja) 2009-12-10
JP2009543851A5 JP2009543851A5 (enExample) 2011-06-23
JP4929352B2 true JP4929352B2 (ja) 2012-05-09

Family

ID=38474429

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009519998A Active JP4929352B2 (ja) 2006-07-18 2006-07-18 注入可能なパラセタモール液剤

Country Status (17)

Country Link
US (2) US9943479B2 (enExample)
EP (2) EP1889607B1 (enExample)
JP (1) JP4929352B2 (enExample)
AT (1) ATE432690T1 (enExample)
AU (2) AU2006346318B2 (enExample)
CA (1) CA2628806C (enExample)
CY (1) CY1110480T1 (enExample)
DE (1) DE602007001215D1 (enExample)
DK (1) DK1889607T3 (enExample)
ES (1) ES2327286T3 (enExample)
HR (1) HRP20090350T1 (enExample)
MA (1) MA31346B1 (enExample)
PL (1) PL1889607T3 (enExample)
PT (1) PT1889607E (enExample)
RU (1) RU2419421C2 (enExample)
SI (1) SI1889607T1 (enExample)
WO (1) WO2008009756A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2926992B1 (fr) * 2008-02-06 2011-01-14 Moly Pharma Formulation d'une solution de paracetamol injectable,procede de preparation et de conditionnement d'une telle solution et dispositif de conditionnement d'une telle solution
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
US8404748B2 (en) 2009-08-13 2013-03-26 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
DK2525796T3 (en) * 2010-01-21 2016-07-04 Aprea Ab An aqueous solution comprising 3-quinuclidinoner for the treatment of hyperproliferative disease, autoimmune disease and heart disease
EP2377516B1 (en) 2010-04-14 2012-06-20 B. Braun Melsungen AG Acetaminophen composition
ES2414557B1 (es) 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
ITMI20121154A1 (it) * 2012-06-29 2013-12-30 Sint Sa Soluzione iniettabile di acetaminofene per la somministrazione spinale
ZA201300398B (en) * 2012-11-27 2013-09-25 Genfarma Laboratories S L Injectable liquid formulation of the combination of tramadol and paracetamol
US20140303254A1 (en) * 2013-04-08 2014-10-09 InnoPharma Licensing LLC Process Of Manufacturing A Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation
BR102014005885B1 (pt) * 2014-03-13 2021-04-13 Biotec Biológica Indústria Farmacêutica Ltda E.P.P Formulação farmacêutica líquida injetável estável de paracetamol em bolsa plástica pronta para uso
WO2016013049A1 (en) * 2014-07-25 2016-01-28 Terumo Kabushiki Kaisha Packaged acetaminophen injection solution preparation
PL3411004T3 (pl) * 2016-02-05 2021-10-18 Innopharma, Inc. Sposób wytwarzania trwałego gotowego do użycia worka infuzyjnego z preparatem wrażliwym na utlenianie

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440815A (en) 1981-06-29 1984-04-03 Abbott Laboratories Clear, autoclavable plastic formulation for medical liquid containers
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
KR100226191B1 (ko) 1997-04-03 1999-10-15 구광시 음료용 플라스틱 병
JP3674685B2 (ja) * 1997-10-23 2005-07-20 森永乳業株式会社 液体の連続式加熱殺菌方法及び装置
DE69736140T2 (de) * 1997-11-18 2007-04-19 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Pharmazeutische injizierbare Lösungen, die Paracetamol und Kombinationen aus Paracetamol mit anderen Aktivsubstanzen enthalten
IT1301976B1 (it) 1998-07-31 2000-07-20 Angelini Ricerche Spa Composizione farmaceutica iniettabile a base di paracetamolo
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
DE10112325A1 (de) 2001-03-13 2002-10-02 Fresenius Kabi De Gmbh Lagerstabile Fertiginfusionslösungen des Paracetamols
ITMI20012135A1 (it) * 2001-10-16 2003-04-16 Bioren S A Soluzioni iniettabili pronte all'uso di paracetamolo
HUP0402549A3 (en) 2001-12-18 2006-01-30 Tseti Ioulia Parenteral composition of paracetamol
EP1508566B1 (en) 2002-05-27 2007-07-18 Kyorin Pharmaceutical Co., Ltd. (2s)-2-ethylphenylpropionic acid derivative
WO2004004705A2 (en) * 2002-07-03 2004-01-15 Shannon Biotechnology Ltd Pharmaceutical formulations for preparing drink products
FR2851164B1 (fr) 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
FR2862872A1 (fr) 2003-12-02 2005-06-03 Palbian Snc Composition a l'etat aqueux pour l'application perfusable d'un principe actif, notamment pharmacologique tel que le paracetamol.
US20060292225A1 (en) 2005-06-24 2006-12-28 Felix Arthur M Water soluble analgesic formulations and methods for production

Also Published As

Publication number Publication date
RU2009105480A (ru) 2010-08-27
CA2628806A1 (en) 2008-01-24
RU2419421C2 (ru) 2011-05-27
ATE432690T1 (de) 2009-06-15
US9943492B2 (en) 2018-04-17
AU2006346318B2 (en) 2011-02-10
SI1889607T1 (sl) 2009-10-31
AU2006346318A1 (en) 2008-01-24
CA2628806C (en) 2012-08-21
US20090215903A1 (en) 2009-08-27
PL1889607T3 (pl) 2009-10-30
PT1889607E (pt) 2009-07-20
EP2100596A3 (en) 2010-04-28
CY1110480T1 (el) 2015-04-29
WO2008009756A1 (es) 2008-01-24
EP2100596A2 (en) 2009-09-16
DK1889607T3 (da) 2009-07-27
JP2009543851A (ja) 2009-12-10
US20160199325A1 (en) 2016-07-14
MA31346B1 (fr) 2010-05-03
AU2011201253B2 (en) 2012-03-29
US9943479B2 (en) 2018-04-17
DE602007001215D1 (de) 2009-07-16
ES2327286T3 (es) 2009-10-27
EP1889607B1 (en) 2009-06-03
HRP20090350T1 (en) 2009-08-31
AU2011201253A1 (en) 2011-04-07
EP1889607A1 (en) 2008-02-20

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