MA31346B1 - Formulation liquide injectable de paracetamol - Google Patents
Formulation liquide injectable de paracetamolInfo
- Publication number
- MA31346B1 MA31346B1 MA31365A MA31365A MA31346B1 MA 31346 B1 MA31346 B1 MA 31346B1 MA 31365 A MA31365 A MA 31365A MA 31365 A MA31365 A MA 31365A MA 31346 B1 MA31346 B1 MA 31346B1
- Authority
- MA
- Morocco
- Prior art keywords
- paracetamol
- injectable
- solution
- liquid formula
- stabilizing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
Abstract
L'invention concerne une solution aqueuse de paracétamol destinée à être utilisée par perfusion et présentant un ph entre 4,5 et 6,0, contenant au moins une substance pouvant réagir avec des phénolates pour générer des o-dérivés ou autres composés de coordination. La solution injectable de paracétamol de la présente invention présente une stabilité élevée, ne se colore pas avec le temps et présente une quantité d'impuretés minimale.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/ES2006/070108 WO2008009756A1 (fr) | 2006-07-18 | 2006-07-18 | Formulation liquide injectable de paracétamol |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31346B1 true MA31346B1 (fr) | 2010-05-03 |
Family
ID=38474429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA31365A MA31346B1 (fr) | 2006-07-18 | 2008-11-07 | Formulation liquide injectable de paracetamol |
Country Status (17)
Country | Link |
---|---|
US (2) | US9943479B2 (fr) |
EP (2) | EP1889607B1 (fr) |
JP (1) | JP4929352B2 (fr) |
AT (1) | ATE432690T1 (fr) |
AU (2) | AU2006346318B2 (fr) |
CA (1) | CA2628806C (fr) |
CY (1) | CY1110480T1 (fr) |
DE (1) | DE602007001215D1 (fr) |
DK (1) | DK1889607T3 (fr) |
ES (1) | ES2327286T3 (fr) |
HR (1) | HRP20090350T1 (fr) |
MA (1) | MA31346B1 (fr) |
PL (1) | PL1889607T3 (fr) |
PT (1) | PT1889607E (fr) |
RU (1) | RU2419421C2 (fr) |
SI (1) | SI1889607T1 (fr) |
WO (1) | WO2008009756A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2926992B1 (fr) * | 2008-02-06 | 2011-01-14 | Moly Pharma | Formulation d'une solution de paracetamol injectable,procede de preparation et de conditionnement d'une telle solution et dispositif de conditionnement d'une telle solution |
EP2243477A1 (fr) | 2009-04-22 | 2010-10-27 | Fresenius Kabi Deutschland GmbH | Paracétamol destiné à l'administration parentérale |
US8404748B2 (en) * | 2009-08-13 | 2013-03-26 | Neogen N.V. | Storage-stable formulation of paracetamol in aqueous solution |
IN2012DN05192A (fr) * | 2010-01-21 | 2015-10-23 | Aprea Ab | |
ES2389760T3 (es) | 2010-04-14 | 2012-10-31 | B. Braun Melsungen Ag | Composición de acetaminofeno |
ES2414557B1 (es) | 2012-01-16 | 2014-06-10 | Novocat Farma, S.A. | Composición acuosa de paracetamol para inyección |
ITMI20121154A1 (it) * | 2012-06-29 | 2013-12-30 | Sint Sa | Soluzione iniettabile di acetaminofene per la somministrazione spinale |
ZA201300398B (en) * | 2012-11-27 | 2013-09-25 | Genfarma Laboratories S L | Injectable liquid formulation of the combination of tramadol and paracetamol |
US20140303254A1 (en) * | 2013-04-08 | 2014-10-09 | InnoPharma Licensing LLC | Process Of Manufacturing A Stable, Ready To Use Infusion Bag For An Oxidation Sensitive Formulation |
BR102014005885B1 (pt) * | 2014-03-13 | 2021-04-13 | Biotec Biológica Indústria Farmacêutica Ltda E.P.P | Formulação farmacêutica líquida injetável estável de paracetamol em bolsa plástica pronta para uso |
EP3171868B1 (fr) * | 2014-07-25 | 2020-09-30 | Terumo Kabushiki Kaisha | Préparation de solution pour injection d'acétaminophène conditionnée |
HUE053952T4 (hu) * | 2016-02-05 | 2021-09-28 | Innopharma Inc | Eljárás oxidációra érzékeny készítményhez stabil, alkalmazásra kész infúziós tasak elõállítására |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4440815A (en) | 1981-06-29 | 1984-04-03 | Abbott Laboratories | Clear, autoclavable plastic formulation for medical liquid containers |
FR2751875B1 (fr) * | 1996-08-05 | 1998-12-24 | Scr Newpharm | Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation |
KR100226191B1 (ko) | 1997-04-03 | 1999-10-15 | 구광시 | 음료용 플라스틱 병 |
DE69840028D1 (de) * | 1997-10-23 | 2008-10-30 | Morinaga Milk Industry Co Ltd | Verfahren sowie vorrichtung zur kontiuierlichen hitzesterilisierung von fluessigkeiten |
DK0916347T3 (da) * | 1997-11-18 | 2003-04-22 | Uni Pharma Kleon Tsetis A B E | Farmaceutiske injicerbare opløsninger der indeholder paracetamol og kombinationer af paracetamol med andre aktive bestanddele |
IT1301976B1 (it) | 1998-07-31 | 2000-07-20 | Angelini Ricerche Spa | Composizione farmaceutica iniettabile a base di paracetamolo |
FR2809619B1 (fr) * | 2000-06-06 | 2004-09-24 | Pharmatop | Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention |
DE10112325A1 (de) | 2001-03-13 | 2002-10-02 | Fresenius Kabi De Gmbh | Lagerstabile Fertiginfusionslösungen des Paracetamols |
ITMI20012135A1 (it) * | 2001-10-16 | 2003-04-16 | Bioren S A | Soluzioni iniettabili pronte all'uso di paracetamolo |
HUP0402549A3 (en) | 2001-12-18 | 2006-01-30 | Tseti Ioulia | Parenteral composition of paracetamol |
CA2487450C (fr) * | 2002-05-27 | 2009-09-22 | Kyorin Pharmaceutical Co., Ltd. | Derive d'acide (2s)-2-ethylphenylpropanoique |
AU2003251152A1 (en) * | 2002-07-03 | 2004-01-23 | Shannon Biotechnology Ltd | Pharmaceutical formulations for preparing drink products |
FR2851164B1 (fr) * | 2003-02-14 | 2005-04-22 | Xuan Tho Nguyen | Formulation liquide injectable de paracetamol |
FR2862872A1 (fr) | 2003-12-02 | 2005-06-03 | Palbian Snc | Composition a l'etat aqueux pour l'application perfusable d'un principe actif, notamment pharmacologique tel que le paracetamol. |
US20060292225A1 (en) | 2005-06-24 | 2006-12-28 | Felix Arthur M | Water soluble analgesic formulations and methods for production |
-
2006
- 2006-07-18 CA CA2628806A patent/CA2628806C/fr active Active
- 2006-07-18 AU AU2006346318A patent/AU2006346318B2/en active Active
- 2006-07-18 WO PCT/ES2006/070108 patent/WO2008009756A1/fr active Application Filing
- 2006-07-18 RU RU2009105480/15A patent/RU2419421C2/ru not_active IP Right Cessation
- 2006-07-18 US US12/084,541 patent/US9943479B2/en active Active
- 2006-07-18 JP JP2009519998A patent/JP4929352B2/ja active Active
-
2007
- 2007-07-12 EP EP07112327A patent/EP1889607B1/fr active Active
- 2007-07-12 EP EP09161268A patent/EP2100596A3/fr not_active Withdrawn
- 2007-07-12 AT AT07112327T patent/ATE432690T1/de active
- 2007-07-12 PL PL07112327T patent/PL1889607T3/pl unknown
- 2007-07-12 ES ES07112327T patent/ES2327286T3/es active Active
- 2007-07-12 SI SI200730058T patent/SI1889607T1/sl unknown
- 2007-07-12 DE DE602007001215T patent/DE602007001215D1/de active Active
- 2007-07-12 DK DK07112327T patent/DK1889607T3/da active
- 2007-07-12 PT PT07112327T patent/PT1889607E/pt unknown
-
2008
- 2008-11-07 MA MA31365A patent/MA31346B1/fr unknown
-
2009
- 2009-06-16 HR HR20090350T patent/HRP20090350T1/xx unknown
- 2009-07-23 CY CY20091100789T patent/CY1110480T1/el unknown
-
2011
- 2011-03-21 AU AU2011201253A patent/AU2011201253B2/en active Active
-
2016
- 2016-03-21 US US15/076,072 patent/US9943492B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
DE602007001215D1 (de) | 2009-07-16 |
CA2628806C (fr) | 2012-08-21 |
US9943479B2 (en) | 2018-04-17 |
PL1889607T3 (pl) | 2009-10-30 |
US20090215903A1 (en) | 2009-08-27 |
ATE432690T1 (de) | 2009-06-15 |
PT1889607E (pt) | 2009-07-20 |
AU2011201253A1 (en) | 2011-04-07 |
SI1889607T1 (sl) | 2009-10-31 |
EP2100596A2 (fr) | 2009-09-16 |
EP2100596A3 (fr) | 2010-04-28 |
ES2327286T3 (es) | 2009-10-27 |
DK1889607T3 (da) | 2009-07-27 |
HRP20090350T1 (en) | 2009-08-31 |
RU2009105480A (ru) | 2010-08-27 |
AU2006346318A1 (en) | 2008-01-24 |
JP4929352B2 (ja) | 2012-05-09 |
US20160199325A1 (en) | 2016-07-14 |
JP2009543851A (ja) | 2009-12-10 |
AU2011201253B2 (en) | 2012-03-29 |
AU2006346318B2 (en) | 2011-02-10 |
EP1889607B1 (fr) | 2009-06-03 |
RU2419421C2 (ru) | 2011-05-27 |
CA2628806A1 (fr) | 2008-01-24 |
US9943492B2 (en) | 2018-04-17 |
WO2008009756A1 (fr) | 2008-01-24 |
CY1110480T1 (el) | 2015-04-29 |
EP1889607A1 (fr) | 2008-02-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA31346B1 (fr) | Formulation liquide injectable de paracetamol | |
ES2485302T3 (es) | Método para proporcionar una nanocelulosa que implica modificar fibras de celulosa | |
CL2013002692A1 (es) | Soluciones estabilizadas de acido hipohaloso y una cantidad estabilizadora de carbono inorganico disuelto; y metodo de preparacion de la misma. | |
DE602006018208D1 (de) | Verfahren zur Verminderung von Alpha, Beta-ungesättigten Ketonen in Opioidzusammensetzungen | |
MA32837B1 (fr) | N-oxyamides spiroheterocycliques etant que pesticides | |
BRPI0706966A8 (pt) | Composição para um efeito microbicida em um sistema de água, método para estabilizar cloro para ser utilizado como um biocida no tratamento de água em um sistema de processamento, e método para tratar um sistema de água de processamento de papel | |
TW200605872A (en) | Alcohol-metabolism enhancing composition and ingesta containing the same | |
TW200633951A (en) | Method for reducing cyclohexenone content of a cyclohexenone-containing organic mixture | |
DK2010014T3 (da) | Solubilisater af konserveringsmidler og fremgangsmåde til fremstilling heraf | |
EA200501132A1 (ru) | 1,2,3-тризамещённые арильные и гетероарильные производные в качестве модуляторов метаболизма и профилактика и лечение расстройств, связанных с ним, таких как диабет и гипергликемия | |
ATE534697T1 (de) | Stabilisator und herstellungsverfahren dafür, thermoplastische polymerzusammensetzung damit und verfahren zur stabilisierung von thermoplastischem polymer | |
PE20060103A1 (es) | Nuevas 5-acilindolinonas con contenido en cicloalquilo y su preparacion como medicamento | |
ATE367167T1 (de) | Aufbereitung von aldesleukin zur pharmazeutischen verwendung | |
ATE493110T1 (de) | Kosmetische zusammensetzung zur stimulierung der synthese der proteine der basalmembran | |
ATE382369T1 (de) | Gebrauchsfertige paracetamol injektionslösungen enthaltend propylenglykol als einziges cosolvens | |
EA200600753A1 (ru) | Скважинная жидкость, содержащая вязкоупругие поверхностно-активные гели с пониженной концентрацией соли | |
SG159481A1 (en) | Stabilization of thermolysin in aqueous solution | |
BRPI0513244A (pt) | composto de clatrato, método para controlar a concentração de solução aquosa de ingrediente ativo quìmico agrìcola e formulação quìmica agrìcola | |
BR112012018427A2 (pt) | uso de composto, e, método para aumentar o ph de uma suspensão aquosa | |
UA92218C2 (ru) | Способ получения стабильного при хранении биодизельного топлива | |
ATE547015T1 (de) | Tabak-katalysator-mischungen zum senken des anteils toxischer verbindungen in tabakrauch | |
DE602004007762D1 (de) | Herbizide zusammensetzung und verwendung | |
BR112013018689A2 (pt) | processo para desaguamento de lodo | |
TH84738B (th) | การใช้ 1-ฟีน็อกซี-2-โพรพานอล(1-phenoxy-2-propanol)เป็นตัวช่วยสูตรสีย้อม | |
RS51179B (sr) | Tečne injektabilne formulacije paracetamola |