JP4862948B2 - 分取精製装置 - Google Patents
分取精製装置 Download PDFInfo
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- JP4862948B2 JP4862948B2 JP2009535885A JP2009535885A JP4862948B2 JP 4862948 B2 JP4862948 B2 JP 4862948B2 JP 2009535885 A JP2009535885 A JP 2009535885A JP 2009535885 A JP2009535885 A JP 2009535885A JP 4862948 B2 JP4862948 B2 JP 4862948B2
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- JP
- Japan
- Prior art keywords
- trap column
- column
- gas
- water
- preparative purification
- Prior art date
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B01D15/203—Equilibration or regeneration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/24—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the treatment of the fractions to be distributed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N30/08—Preparation using an enricher
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N30/54—Temperature
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/80—Fraction collectors
Description
a)前記溶媒に代えて乾燥用ガスを前記トラップカラムの入口端から該カラムに導入するガス供給手段と、
b)前記目的成分が捕集された前記トラップカラムに対し溶出用の前記溶媒を流す前に、所定時間の間又は前記トラップカラム内部の乾燥が終了したと判断できる時点まで前記乾燥用ガスを流すように前記ガス供給手段を制御する制御手段と、
を備えることを特徴としている。
2…洗浄水容器
3…溶出用溶媒容器
4…切替バルブ
5…送液ポンプ
6…開閉バルブ
7…高圧6方バルブ
8…供給側流路
10…熱交換ブロック
11…ヒータ
12…温度センサ
13…ガス温調部
14…トラップカラム
14a…入口端
14b…出口端
15…カラムラック
16…ヒータ
17…温度センサ
18…カラム温調部
20…排出側流路
21…分取ヘッド
22…2方切替バルブ
23…分取流路
23a…溶液ノズル
24…廃液流路
25…ガス流路
25a…ガス噴出ノズル
26…開閉バルブ
27…回収容器
28…容器ラック
29…ヒータ
30…温度センサ
35…制御部
36…操作部
37…水分センサ
Claims (4)
- 入口端が下方、出口端が上方に指向するように保持されたトラップカラムに目的成分を含む溶液を流して該目的成分を前記トラップカラム中に捕集し、その後に前記入口端から溶出力を有する溶媒を前記トラップカラムに流し、該トラップカラム中に捕集されていた目的成分を溶出させて回収するための分取精製装置において、
a)前記溶媒に代えて乾燥用ガスを前記トラップカラムの入口端から該トラップカラムに導入するガス供給手段と、
b)前記目的成分が捕集された前記トラップカラムに対し溶出用の前記溶媒を流す前に、所定時間の間又は前記トラップカラム内部の乾燥が終了したと判断できる時点まで前記乾燥用ガスを流すように前記ガス供給手段を制御する制御手段と、
を備えることを特徴とする分取精製装置。 - 請求項1に記載の分取精製装置であって、前記ガス供給手段は、前記乾燥用ガス、前記溶媒、又は前記目的成分を含む溶液の1つを前記トラップカラムに流通させるように流路を切り替える流路切替手段を含むことを特徴とする分取精製装置。
- 請求項1又は2に記載の分取精製装置であって、前記トラップカラムに供給される前記乾燥用ガスを加熱するガス加熱手段を備えることを特徴とする分取精製装置。
- 請求項3に記載の分取精製装置であって、前記トラップカラムを加熱するカラム加熱手段を備えることを特徴とする分取精製装置。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2007/001069 WO2009044425A1 (ja) | 2007-10-02 | 2007-10-02 | 分取精製装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2009044425A1 JPWO2009044425A1 (ja) | 2011-01-27 |
JP4862948B2 true JP4862948B2 (ja) | 2012-01-25 |
Family
ID=40525859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009535885A Active JP4862948B2 (ja) | 2007-10-02 | 2007-10-02 | 分取精製装置 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8974666B2 (ja) |
JP (1) | JP4862948B2 (ja) |
GB (1) | GB2465957B (ja) |
WO (1) | WO2009044425A1 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5532999B2 (ja) * | 2010-02-15 | 2014-06-25 | 株式会社島津製作所 | 分取精製装置 |
US10124270B2 (en) | 2011-07-26 | 2018-11-13 | Shimadzu Corporation | Gas blowing vaporizing and drying device |
JP5849896B2 (ja) | 2012-08-22 | 2016-02-03 | 株式会社島津製作所 | ガス吹付式蒸発・乾固装置 |
US9884266B2 (en) * | 2013-07-08 | 2018-02-06 | Orlab Chromatography, Llc | Fluoropolymer pneumatically/hydraulically actuated liquid chromatographic system for use with harsh reagents |
US9630125B2 (en) | 2015-06-08 | 2017-04-25 | Shimadzu Corporation | Gas-blowing liquid sample infusing device and infusion container used for the same |
CN107923887B (zh) | 2015-08-24 | 2020-06-16 | 株式会社岛津制作所 | 分离纯化装置 |
US20180238841A1 (en) * | 2015-10-02 | 2018-08-23 | Shimadzu Corporation | Preparative separation and purification device and preparative separation and purification method |
US10184918B2 (en) | 2016-10-07 | 2019-01-22 | Shimadzu Corporation | Gas-spouting liquid-sample injector and injection container for the same |
JP7437276B2 (ja) | 2020-09-18 | 2024-02-22 | オルガノ株式会社 | イオン交換体の分析方法及びイオン交換体の前処理装置 |
Citations (6)
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JP2002202316A (ja) * | 2000-11-01 | 2002-07-19 | Jeol Ltd | 分析システムおよび分析方法 |
JP2002257806A (ja) * | 2001-03-05 | 2002-09-11 | Hitachi Ltd | フラン環成分分析システム及び分析方法 |
JP2004093194A (ja) * | 2002-08-29 | 2004-03-25 | Ngk Insulators Ltd | カラム処理装置 |
JP2005009940A (ja) * | 2003-06-17 | 2005-01-13 | Miura Co Ltd | ダイオキシン類分析用試料の調製方法および調製装置並びにダイオキシン類分析用試料の採取装置 |
WO2007026693A1 (ja) * | 2005-08-30 | 2007-03-08 | Saika Technological Institute Foundation | 有機化学物質の分析前処理装置及びその分析前処理方法 |
JP2008241546A (ja) * | 2007-03-28 | 2008-10-09 | Hitachi High-Technologies Corp | 固相抽出カラムの水分除去確認方法及び固相抽出カラムの水分除去確認装置並びに固相抽出カラム |
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US4380496A (en) * | 1979-03-22 | 1983-04-19 | Uop Inc. | Mechanical dewatering process utilizing a nonuniform screw conveyor |
US5039488A (en) * | 1986-06-06 | 1991-08-13 | Genentech, Inc. | Devices for amino acid sequence determination |
US5223435A (en) * | 1986-06-06 | 1993-06-29 | Genetech, Inc. | Amino acid sequence determination with mobile peptide |
JP2556115B2 (ja) | 1988-10-31 | 1996-11-20 | 株式会社島津製作所 | 分取用液体クロマトグラフ |
US5496733A (en) * | 1994-08-19 | 1996-03-05 | Spandau; Daniel J. | Discharge monitoring system |
US6041515A (en) * | 1998-01-12 | 2000-03-28 | Life Technologies, Inc. | Apparatus for drying solutions containing macromolecules |
JP3719407B2 (ja) | 2001-11-13 | 2005-11-24 | 株式会社島津製作所 | 分取液体クロマトグラフ |
US7332013B2 (en) * | 2004-03-15 | 2008-02-19 | Arno Michael J | Compressed air/gas-driven tool with integrated dryness indicator |
WO2009044428A1 (ja) * | 2007-10-02 | 2009-04-09 | Shimadzu Corporation | 分取精製装置 |
US8607620B2 (en) * | 2007-10-02 | 2013-12-17 | Shimadzu Corporation | Preparative separation/purification system |
WO2009044427A1 (ja) * | 2007-10-02 | 2009-04-09 | Shimadzu Corporation | 分取精製装置 |
US7883619B2 (en) * | 2007-11-13 | 2011-02-08 | Access Business Group International Llc | Water treatment system with moisture detector |
-
2007
- 2007-10-02 WO PCT/JP2007/001069 patent/WO2009044425A1/ja active Application Filing
- 2007-10-02 GB GB1006553.0A patent/GB2465957B/en active Active
- 2007-10-02 JP JP2009535885A patent/JP4862948B2/ja active Active
- 2007-10-02 US US12/681,281 patent/US8974666B2/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2002202316A (ja) * | 2000-11-01 | 2002-07-19 | Jeol Ltd | 分析システムおよび分析方法 |
JP2002257806A (ja) * | 2001-03-05 | 2002-09-11 | Hitachi Ltd | フラン環成分分析システム及び分析方法 |
JP2004093194A (ja) * | 2002-08-29 | 2004-03-25 | Ngk Insulators Ltd | カラム処理装置 |
JP2005009940A (ja) * | 2003-06-17 | 2005-01-13 | Miura Co Ltd | ダイオキシン類分析用試料の調製方法および調製装置並びにダイオキシン類分析用試料の採取装置 |
WO2007026693A1 (ja) * | 2005-08-30 | 2007-03-08 | Saika Technological Institute Foundation | 有機化学物質の分析前処理装置及びその分析前処理方法 |
JP2008241546A (ja) * | 2007-03-28 | 2008-10-09 | Hitachi High-Technologies Corp | 固相抽出カラムの水分除去確認方法及び固相抽出カラムの水分除去確認装置並びに固相抽出カラム |
Also Published As
Publication number | Publication date |
---|---|
WO2009044425A1 (ja) | 2009-04-09 |
GB201006553D0 (en) | 2010-06-02 |
GB2465957A (en) | 2010-06-09 |
GB2465957B (en) | 2012-04-04 |
JPWO2009044425A1 (ja) | 2011-01-27 |
US8974666B2 (en) | 2015-03-10 |
US20100258485A1 (en) | 2010-10-14 |
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