JP4828405B2 - 呼吸器官の細菌性疾患の処置 - Google Patents

呼吸器官の細菌性疾患の処置 Download PDF

Info

Publication number
JP4828405B2
JP4828405B2 JP2006501628A JP2006501628A JP4828405B2 JP 4828405 B2 JP4828405 B2 JP 4828405B2 JP 2006501628 A JP2006501628 A JP 2006501628A JP 2006501628 A JP2006501628 A JP 2006501628A JP 4828405 B2 JP4828405 B2 JP 4828405B2
Authority
JP
Japan
Prior art keywords
administration
inhalation
solid
ciprofloxacin
betaine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006501628A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006517210A (ja
Inventor
ライナー・エンダーマン
ハラルト・ラビシンスキー
クリストフ・ラデル
ウヴェ・ペーターゼン
ベン・ニュートン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32851853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4828405(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10305318A external-priority patent/DE10305318A1/de
Priority claimed from DE10305319A external-priority patent/DE10305319A1/de
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of JP2006517210A publication Critical patent/JP2006517210A/ja
Application granted granted Critical
Publication of JP4828405B2 publication Critical patent/JP4828405B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
JP2006501628A 2003-02-10 2004-01-28 呼吸器官の細菌性疾患の処置 Expired - Fee Related JP4828405B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10305318A DE10305318A1 (de) 2003-02-10 2003-02-10 Behandlung bakteriell verursachter Lungenkrankheiten
DE10305318.2 2003-02-10
DE10305319A DE10305319A1 (de) 2003-02-10 2003-02-10 Behandlung bakteriell verursachter Lungenkrankheiten
DE10305319.0 2003-02-10
PCT/EP2004/000710 WO2004069253A1 (de) 2003-02-10 2004-01-28 Behandlung bakterieller erkrankungen der atmungsorgane durch lokale applikation von fluorchinolonen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011128600A Division JP2011173929A (ja) 2003-02-10 2011-06-08 呼吸器官の細菌性疾患の処置

Publications (2)

Publication Number Publication Date
JP2006517210A JP2006517210A (ja) 2006-07-20
JP4828405B2 true JP4828405B2 (ja) 2011-11-30

Family

ID=32851853

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006501628A Expired - Fee Related JP4828405B2 (ja) 2003-02-10 2004-01-28 呼吸器官の細菌性疾患の処置
JP2011128600A Pending JP2011173929A (ja) 2003-02-10 2011-06-08 呼吸器官の細菌性疾患の処置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011128600A Pending JP2011173929A (ja) 2003-02-10 2011-06-08 呼吸器官の細菌性疾患の処置

Country Status (28)

Country Link
US (2) US8034817B2 (de)
EP (1) EP1594500B1 (de)
JP (2) JP4828405B2 (de)
KR (1) KR101173696B1 (de)
AR (1) AR043117A1 (de)
AT (1) ATE482706T1 (de)
AU (1) AU2004210399B2 (de)
BR (1) BRPI0407368A (de)
CA (1) CA2515262C (de)
CY (1) CY1110998T1 (de)
DE (1) DE502004011696D1 (de)
DK (1) DK1594500T3 (de)
EC (1) ECSP055959A (de)
HK (1) HK1089380A1 (de)
HR (1) HRP20050786B1 (de)
IL (1) IL170027A (de)
MA (1) MA27632A1 (de)
MX (1) MXPA05008407A (de)
MY (1) MY144714A (de)
NO (1) NO331524B1 (de)
NZ (1) NZ541681A (de)
PE (1) PE20050189A1 (de)
PT (1) PT1594500E (de)
RU (1) RU2373937C9 (de)
SI (1) SI1594500T1 (de)
TW (1) TWI347843B (de)
UY (1) UY28179A1 (de)
WO (1) WO2004069253A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ541681A (en) * 2003-02-10 2009-02-28 Bayer Healthcare Ag Treatment of bacterial diseases of the respiratory organs by locally applying ciprofloxacin and its salts
US7157455B2 (en) * 2003-02-10 2007-01-02 Hoffmann-La Roche Inc. 4-Aminopyrimidine-5-one derivatives
WO2006033713A2 (en) * 2004-08-09 2006-03-30 Chiron Corporation Methods for ciprofloxacin inhalation
CA2585859C (en) 2004-10-29 2012-03-06 President And Fellows Of Harvard College Particles for treatment of pulmonary infection
LT1901749T (lt) * 2005-05-18 2016-10-25 Raptor Pharmaceuticals Inc. Aerozoliniai fluorchinolinai ir jų naudojimas
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
EP2285345A1 (de) 2008-05-15 2011-02-23 Novartis AG Pulmonale freisetzung eines fluorchinolons
JP2012505222A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 肺炎症を低減するためのレボフロキサシンの吸入
JP2012505223A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 薬物動態の改善のためのエアゾールフルオロキノロン配合物
WO2010048341A1 (en) 2008-10-22 2010-04-29 Inspire Pharmaceuticals, Inc. Method for treating cystic fibrosis
AU2010289326B2 (en) 2009-09-04 2015-09-24 Horizon Therapeutics U.S. Holding Llc Use of aerosolized levofloxacin for treating cystic fibrosis
US9393243B1 (en) 2015-07-14 2016-07-19 Nilesh Parikh Topical Ciprofloxacin compositions
WO2018074880A2 (ko) * 2016-10-20 2018-04-26 한국화학연구원 퀴놀린 4-온 유도체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 폐렴의 예방 또는 치료용 약학적 조성물

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6219569A (ja) * 1985-07-16 1987-01-28 バイエル・アクチエンゲゼルシヤフト キノロンカルボン酸類のエンボネート類
JPH04327527A (ja) * 1991-03-14 1992-11-17 Ciba Geigy Ag 医薬エアロゾール配合物
JPH05255072A (ja) * 1992-01-15 1993-10-05 Bayer Ag フレーバーマスクされた薬学的組成物
WO1999048542A1 (de) * 1998-03-20 1999-09-30 Bayer Aktiengesellschaft Formkörper aus wirkstoffhaltigen thermoplastischen polyurethanen
WO2001032144A1 (en) * 1999-10-29 2001-05-10 Inhale Therapeutic Systems, Inc. Dry powder compositions having improved dispersivity

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033157A1 (de) 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
DE3906365A1 (de) 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
FR2655545B1 (fr) * 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
DE19633480A1 (de) * 1996-08-20 1998-02-26 Bayer Ag Oral applizierbare Formulierungen von Chinolon- und Naphthyridoncarbonsäuren
AU5528299A (en) * 1998-09-15 2000-04-03 Naeja Pharmaceutical Inc. Combined therapy for treatment of inflammation using elastase inhibitor(s) and antibacterial agent(s)
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
EP1490027A4 (de) * 2002-03-05 2010-11-10 Transave Inc Verfahren zum einfangen eines wirkstoffs in einem liposom oder lipidkomplex
WO2003090715A2 (en) * 2002-04-25 2003-11-06 Nektar Therapeutics Uk Ltd Particulate materials
NZ541681A (en) * 2003-02-10 2009-02-28 Bayer Healthcare Ag Treatment of bacterial diseases of the respiratory organs by locally applying ciprofloxacin and its salts

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6219569A (ja) * 1985-07-16 1987-01-28 バイエル・アクチエンゲゼルシヤフト キノロンカルボン酸類のエンボネート類
JPH04327527A (ja) * 1991-03-14 1992-11-17 Ciba Geigy Ag 医薬エアロゾール配合物
JPH05255072A (ja) * 1992-01-15 1993-10-05 Bayer Ag フレーバーマスクされた薬学的組成物
WO1999048542A1 (de) * 1998-03-20 1999-09-30 Bayer Aktiengesellschaft Formkörper aus wirkstoffhaltigen thermoplastischen polyurethanen
WO2001032144A1 (en) * 1999-10-29 2001-05-10 Inhale Therapeutic Systems, Inc. Dry powder compositions having improved dispersivity

Also Published As

Publication number Publication date
MXPA05008407A (es) 2005-10-05
JP2011173929A (ja) 2011-09-08
PE20050189A1 (es) 2005-05-22
UY28179A1 (es) 2004-09-30
RU2373937C9 (ru) 2010-07-27
DK1594500T3 (da) 2011-01-24
RU2373937C2 (ru) 2009-11-27
AU2004210399A1 (en) 2004-08-19
RU2005128132A (ru) 2006-02-10
SI1594500T1 (sl) 2011-02-28
CA2515262C (en) 2013-09-03
BRPI0407368A (pt) 2006-02-14
MA27632A1 (fr) 2005-11-01
CA2515262A1 (en) 2004-08-19
NO20054180D0 (no) 2005-09-08
WO2004069253A1 (de) 2004-08-19
US8034817B2 (en) 2011-10-11
TWI347843B (en) 2011-09-01
DE502004011696D1 (de) 2010-11-11
ECSP055959A (es) 2006-01-16
US20040254194A1 (en) 2004-12-16
IL170027A (en) 2012-02-29
EP1594500A1 (de) 2005-11-16
PT1594500E (pt) 2010-12-17
EP1594500B1 (de) 2010-09-29
HRP20050786A2 (en) 2006-10-31
NO20054180L (no) 2005-09-08
JP2006517210A (ja) 2006-07-20
US20120010215A1 (en) 2012-01-12
AU2004210399B2 (en) 2010-02-18
AR043117A1 (es) 2005-07-20
MY144714A (en) 2011-10-31
CY1110998T1 (el) 2015-06-11
KR20050098309A (ko) 2005-10-11
NZ541681A (en) 2009-02-28
HK1089380A1 (en) 2006-12-01
KR101173696B1 (ko) 2012-08-13
HRP20050786B1 (hr) 2015-01-02
TW200503716A (en) 2005-02-01
ATE482706T1 (de) 2010-10-15
NO331524B1 (no) 2012-01-23

Similar Documents

Publication Publication Date Title
JP2011173929A (ja) 呼吸器官の細菌性疾患の処置
EP2670242B1 (de) Aerosolförmige pirfenidon- und pyridonanalogverbindungen und verwendungen davon
EP2259773B1 (de) Makrolidzusammensetzungen mit verbessertem geschmack und erhöhter stabilität
EP2877164B1 (de) Aerosolpirfenidon und pyridonanalogverbindungen
WO2007014673A2 (en) Pharmaceutical formulations comprising a long-acting beta2-agonist for administration by nebulisation
JP2009526003A (ja) 吸入療法用噴霧状抗生物質
JP2008513444A (ja) リドカイン及び他の局所麻酔剤の標的運搬並びに咳そう及び咳の発作の処置のための方法
JP2014525471A (ja) 咳および咳発作の治療
EP3463325B1 (de) Mikropartikel mit einer schwefelhaltigen verbindung
WO2021211858A1 (en) Inhalable formulation of a solution containing tiotropium bromide and olodaterol
WO2006033713A2 (en) Methods for ciprofloxacin inhalation
JP2002532405A (ja) オピオイド吸入製剤
EP2313114B1 (de) Arzneimittelpulver zur inhalation und verfahren dafür
CA2928736A1 (en) Inhaled aerosolized immuno-chemotherapy for the treatment of mdr tb
ZA200506287B (en) Treatment of bacterial of the respiratory organs by locally applying fluoroquinolones
US11110085B2 (en) Co-spray drying of ciprofloxacin and colistin and the uses thereof
ES2352729T3 (es) Tratamiento de enfermedades bacterianas de los órganos respiratorios mediante administración local de fluoroquinolonas.
CN112569211A (zh) 一种吸入用加替沙星溶液及其制备方法
TWI762449B (zh) 噴霧器用組成物
WO2021211854A1 (en) Inhalable formulation of a solution containing tiotropium bromide
KR20230052903A (ko) 흡입 투여를 위한 병용 요법

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070124

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20090907

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20090907

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100316

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100616

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100623

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100702

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110208

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110608

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20110630

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110823

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110914

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140922

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 4828405

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140922

Year of fee payment: 3

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140922

Year of fee payment: 3

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees