JP4808406B2 - 表面に液体を流すための方法および装置 - Google Patents

表面に液体を流すための方法および装置 Download PDF

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Publication number
JP4808406B2
JP4808406B2 JP2004556622A JP2004556622A JP4808406B2 JP 4808406 B2 JP4808406 B2 JP 4808406B2 JP 2004556622 A JP2004556622 A JP 2004556622A JP 2004556622 A JP2004556622 A JP 2004556622A JP 4808406 B2 JP4808406 B2 JP 4808406B2
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port
liquid
flow path
pressure
flow
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Expired - Fee Related
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JP2004556622A
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Japanese (ja)
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JP2006508789A (ja
JP2006508789A5 (enExample
Inventor
デラマルシェ、エマニュエル
ユンカー、ダビッド
マイケル、ブルーノ
シュミット、ハインツ
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International Business Machines Corp
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International Business Machines Corp
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0262—Drop counters; Drop formers using touch-off at substrate or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
    • B01J8/20—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles with liquid as a fluidising medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C5/00—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
    • B05C5/02—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B01J2219/00367—Pipettes capillary
    • B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/0038—Drawing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00427—Means for dispensing and evacuation of reagents using masks
    • B01J2219/0043—Means for dispensing and evacuation of reagents using masks for direct application of reagents, e.g. through openings in a shutter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/10—Means to control humidity and/or other gases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/022—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/9682—Miscellaneous
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Combustion & Propulsion (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
JP2004556622A 2002-12-05 2003-11-13 表面に液体を流すための方法および装置 Expired - Fee Related JP4808406B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02027180 2002-12-05
EP02027180.5 2002-12-05
PCT/IB2003/005350 WO2004050246A1 (en) 2002-12-05 2003-11-13 Method and device for flowing a liquid on a surface

Publications (3)

Publication Number Publication Date
JP2006508789A JP2006508789A (ja) 2006-03-16
JP2006508789A5 JP2006508789A5 (enExample) 2006-12-28
JP4808406B2 true JP4808406B2 (ja) 2011-11-02

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JP2004556622A Expired - Fee Related JP4808406B2 (ja) 2002-12-05 2003-11-13 表面に液体を流すための方法および装置

Country Status (8)

Country Link
US (2) US7329111B2 (enExample)
EP (1) EP1567265B1 (enExample)
JP (1) JP4808406B2 (enExample)
KR (1) KR100702504B1 (enExample)
CN (1) CN100562362C (enExample)
AU (1) AU2003283627A1 (enExample)
TW (1) TWI245739B (enExample)
WO (1) WO2004050246A1 (enExample)

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EP2506976A2 (en) 2009-12-03 2012-10-10 Owe Owar Pipettes, methods of use, and methods of stimulating an object of interest
ITMI20100407A1 (it) * 2010-03-12 2011-09-13 Rise Technology S R L Cella foto-voltaica con regioni di semiconduttore poroso per ancorare terminali di contatto
EP2704834A2 (en) * 2011-05-06 2014-03-12 Owe Orwar Microfluidic device with holding interface, and method of use
JP6318094B2 (ja) 2012-02-27 2018-05-09 エコール ポリテクニーク フェデラーレ ドゥ ローザンヌ（エペエフエル）Ｅｃｏｌｅ Ｐｏｌｙｔｅｃｈｎｉｑｕｅ Ｆｅｄｅｒａｌｅ ｄｅ Ｌａｕｓａｎｎｅ（ＥＰＦＬ） スライドが着脱可能な試料処理デバイス
WO2013183013A1 (en) 2012-06-06 2013-12-12 De Oliva Novo Pedro Jose Autonomous and programmable sequential flow of solutions in capillary microfluidics
US9021864B2 (en) 2012-08-21 2015-05-05 International Business Machines Corporation Sensing biomolecules using scanning probe with twin-nanopore to detect a change in the magnitude of the current through the second nanopore
DE102013205889B3 (de) 2013-04-03 2014-05-28 Kennametal Inc. Kupplungsteil, insbesondere Schneidkopf für ein Rotationswerkzeug sowie ein derartiges Rotationswerkzeug
DE102013220884B4 (de) 2013-10-15 2022-02-17 Kennametal Inc. Modulares Trägerwerkzeug sowie Werkzeugkopf
CN103808776B (zh) * 2014-03-12 2017-11-14 杭州霆科生物科技有限公司 电化学传感器的制备方法
DE102014206796B4 (de) 2014-04-08 2020-10-15 Kennametal Inc. Rotationswerkzeug, insbesondere Bohrer sowie Schneidkopf für ein solches Rotationswerkzeug
CN107666961B (zh) 2015-01-14 2021-08-10 伯乐实验室公司 血液分析系统和方法
WO2016118757A1 (en) 2015-01-23 2016-07-28 Bio-Rad Laboratories, Inc. Immunoblotting systems and methods
DE102015211744B4 (de) 2015-06-24 2023-07-20 Kennametal Inc. Rotationswerkzeug, insbesondere Bohrer, und Schneidkopf für ein solches Rotationswerkzeug
US9937567B2 (en) 2015-10-07 2018-04-10 Kennametal Inc. Modular drill
USD798921S1 (en) 2015-10-07 2017-10-03 Kennametal Inc. Cutting head for modular drill
USD798922S1 (en) 2015-10-07 2017-10-03 Kennametal Inc. Cutting head for rotary drill
US10071430B2 (en) 2015-10-07 2018-09-11 Kennametal Inc. Cutting head, rotary tool and support for the rotary tool and for the accommodation of the cutting head
DE102017205166B4 (de) 2017-03-27 2021-12-09 Kennametal Inc. Modulares Rotationswerkzeug und modulares Werkzeugsystem
DE102017212054B4 (de) 2017-07-13 2019-02-21 Kennametal Inc. Verfahren zur Herstellung eines Schneidkopfes sowie Schneidkopf
US10799958B2 (en) 2017-08-21 2020-10-13 Kennametal Inc. Modular rotary cutting tool
WO2020069609A1 (en) * 2018-10-01 2020-04-09 Gervais Thomas System and method of fluid delivery
US11298769B2 (en) 2019-05-13 2022-04-12 International Business Machines Corporation Prevention of dripping of material for material injection
CN112077370B (zh) 2019-06-13 2024-10-01 肯纳金属印度有限公司 可转位钻头刀片
EP3766577A1 (en) 2019-07-16 2021-01-20 Imec VZW Passive fluidic connection between two hydrophilic substrates
CN115703157A (zh) 2021-08-17 2023-02-17 肯纳金属印度有限公司 具有冷却剂系统的可转位钻头组件
JP2023042882A (ja) * 2021-09-15 2023-03-28 株式会社Ｓｃｒｅｅｎホールディングス 流路デバイス

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Publication number Priority date Publication date Assignee Title
US3526694A (en) * 1968-02-06 1970-09-01 Jerome H Lemelson Molding techniques
US6231333B1 (en) * 1995-08-24 2001-05-15 International Business Machines Corporation Apparatus and method for vacuum injection molding
JP2003530566A (ja) * 2000-04-06 2003-10-14 カリパー・テクノロジーズ・コープ． 保護層を組み込んだミクロ流体装置及びシステム
US20020117517A1 (en) * 2000-11-16 2002-08-29 Fluidigm Corporation Microfluidic devices for introducing and dispensing fluids from microfluidic systems
JP2005506529A (ja) * 2001-10-16 2005-03-03 アプレラ コーポレイション 液体で基板チャンバを充填するためのシステム

Also Published As

Publication number Publication date
CN1720101A (zh) 2006-01-11
KR20050084968A (ko) 2005-08-29
CN100562362C (zh) 2009-11-25
US20060093697A1 (en) 2006-05-04
US7329111B2 (en) 2008-02-12
WO2004050246A1 (en) 2004-06-17
KR100702504B1 (ko) 2007-04-03
TWI245739B (en) 2005-12-21
JP2006508789A (ja) 2006-03-16
US7740472B2 (en) 2010-06-22
US20080000536A1 (en) 2008-01-03
AU2003283627A1 (en) 2004-06-23
EP1567265B1 (en) 2014-07-02
EP1567265A1 (en) 2005-08-31
TW200415115A (en) 2004-08-16

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