JP4804363B2 - 蛍光顕微鏡装置 - Google Patents

蛍光顕微鏡装置 Download PDF

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Publication number
JP4804363B2
JP4804363B2 JP2006551974A JP2006551974A JP4804363B2 JP 4804363 B2 JP4804363 B2 JP 4804363B2 JP 2006551974 A JP2006551974 A JP 2006551974A JP 2006551974 A JP2006551974 A JP 2006551974A JP 4804363 B2 JP4804363 B2 JP 4804363B2
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Japan
Prior art keywords
sample
field
fluorescent
microscope
uniform
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Expired - Fee Related
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JP2006551974A
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English (en)
Japanese (ja)
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JP2007522502A5 (enExample
JP2007522502A (ja
Inventor
ベルンハルド グライヒ
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Koninklijke Philips NV
Original Assignee
Koninklijke Philips NV
Koninklijke Philips Electronics NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
JP2006551974A 2004-02-09 2005-01-27 蛍光顕微鏡装置 Expired - Fee Related JP4804363B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04100462 2004-02-09
EP04100462.3 2004-02-09
PCT/IB2005/050354 WO2005076050A1 (en) 2004-02-09 2005-01-27 Fluorescence microscope arrangement

Publications (3)

Publication Number Publication Date
JP2007522502A JP2007522502A (ja) 2007-08-09
JP2007522502A5 JP2007522502A5 (enExample) 2011-04-21
JP4804363B2 true JP4804363B2 (ja) 2011-11-02

Family

ID=34833743

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006551974A Expired - Fee Related JP4804363B2 (ja) 2004-02-09 2005-01-27 蛍光顕微鏡装置

Country Status (7)

Country Link
US (1) US20070161075A1 (enExample)
EP (1) EP1716444B1 (enExample)
JP (1) JP4804363B2 (enExample)
CN (1) CN100526932C (enExample)
AT (1) ATE418084T1 (enExample)
DE (1) DE602005011763D1 (enExample)
WO (1) WO2005076050A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060248944A1 (en) * 2003-04-15 2006-11-09 Koninklijke Philips Electronics N.V. Method to determine the spatial distribution of magnetic particles and magnetic particle administering compositions
DE102005017817A1 (de) * 2005-04-18 2006-10-26 Siemens Ag Verfahren und Vorrichtung zur Untersuchung eines biologischen Gewebes
WO2007015190A2 (en) * 2005-08-01 2007-02-08 Philips Intellectual Property & Standards Gmbh Optical imaging
JP2011022201A (ja) * 2009-07-13 2011-02-03 Jikei Univ 顕微鏡装置用の光源装置、及び光源装置付き観察試料載置具、並びに顕微鏡装置
EP3955042B1 (en) 2013-08-26 2024-08-21 S.D. Sight Diagnostics Ltd. Digital microscopy systems, methods and computer program products
CN103575716A (zh) * 2013-11-15 2014-02-12 中国科学院长春应用化学研究所 磁场调控的超分辨荧光成像方法
CA2998829A1 (en) 2015-09-17 2017-03-23 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
EP3436864B1 (en) 2016-03-30 2021-04-28 S.D. Sight Diagnostics Ltd. Image processing device for identifying blood parasites
WO2017195205A1 (en) 2016-05-11 2017-11-16 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements
AU2017263807B2 (en) 2016-05-11 2023-02-02 S.D. Sight Diagnostics Ltd Performing optical measurements on a sample
JP7214729B2 (ja) 2017-11-14 2023-01-30 エス．ディー．サイト ダイアグノスティクス リミテッド 光学測定用試料収容器
DE102018206406C5 (de) 2018-04-25 2025-05-15 Carl Zeiss Meditec Ag Mikroskopiesystem
CA3155820A1 (en) 2019-10-22 2021-04-29 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
WO2021116962A1 (en) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Artificial generation of color blood smear image
CA3160695A1 (en) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578167A (en) * 1982-09-28 1986-03-25 Biofusion, Inc. Cell fusion
US4676640A (en) * 1984-09-12 1987-06-30 Syntex (U.S.A.) Inc. Fluctuation analysis for enhanced particle detection
DE19508366C2 (de) * 1995-03-10 1998-01-29 Evotec Biosystems Gmbh Verfahren zum direkten Nachweisen weniger Nucleinsäurestränge
MY139225A (en) * 1998-02-26 2009-08-28 Anglo Operations Ltd Method and apparatus for separating particles
DE19903001A1 (de) * 1999-01-26 2000-08-24 Evotec Biosystems Ag Verfahren und Vorrichtung zur Detektion mikroskopisch kleiner Objekte
US6271660B1 (en) * 1999-06-11 2001-08-07 Mts Sytems Corporation Permanent multi-pole position magnet
US6437551B1 (en) * 1999-11-02 2002-08-20 The Regents Of The University Of California Microfabricated AC impedance sensor
JP4994560B2 (ja) * 2000-08-25 2012-08-08 アムニス コーポレイション 細胞などの小さな移動物体の速度測定
DE10103304A1 (de) * 2001-01-25 2002-08-01 Gnothis Holding Sa Ecublens Verfahren zur fluoreszenzspektroskopischen, insbesondere fluoreszenzkorrelationsspektroskopischen Untersuchung einer Messprobe sowie Einrichtung zur Durchführung desselben
US20020127144A1 (en) * 2001-03-08 2002-09-12 Mehta Shailesh P. Device for analyzing particles and method of use
US7968305B2 (en) * 2001-03-24 2011-06-28 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
DE10151778A1 (de) * 2001-10-19 2003-05-08 Philips Corp Intellectual Pty Verfahren zur Ermittlung der räumlichen Verteilung magnetischer Partikel
JP4890242B2 (ja) * 2003-04-15 2012-03-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 検査エリアにおける状態変数の空間分解を決定する装置及び方法

Also Published As

Publication number Publication date
CN1918501A (zh) 2007-02-21
US20070161075A1 (en) 2007-07-12
DE602005011763D1 (de) 2009-01-29
EP1716444A1 (en) 2006-11-02
ATE418084T1 (de) 2009-01-15
CN100526932C (zh) 2009-08-12
WO2005076050A1 (en) 2005-08-18
EP1716444B1 (en) 2008-12-17
JP2007522502A (ja) 2007-08-09

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