ATE418084T1 - Fluoreszenz-mikroskop-anordnung - Google Patents

Fluoreszenz-mikroskop-anordnung

Info

Publication number
ATE418084T1
ATE418084T1 AT05702809T AT05702809T ATE418084T1 AT E418084 T1 ATE418084 T1 AT E418084T1 AT 05702809 T AT05702809 T AT 05702809T AT 05702809 T AT05702809 T AT 05702809T AT E418084 T1 ATE418084 T1 AT E418084T1
Authority
AT
Austria
Prior art keywords
sample
microscope
fluorescence
distribution
focal region
Prior art date
Application number
AT05702809T
Other languages
English (en)
Inventor
Bernhard Gleich
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE418084T1 publication Critical patent/ATE418084T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
AT05702809T 2004-02-09 2005-01-27 Fluoreszenz-mikroskop-anordnung ATE418084T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04100462 2004-02-09

Publications (1)

Publication Number Publication Date
ATE418084T1 true ATE418084T1 (de) 2009-01-15

Family

ID=34833743

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05702809T ATE418084T1 (de) 2004-02-09 2005-01-27 Fluoreszenz-mikroskop-anordnung

Country Status (7)

Country Link
US (1) US20070161075A1 (de)
EP (1) EP1716444B1 (de)
JP (1) JP4804363B2 (de)
CN (1) CN100526932C (de)
AT (1) ATE418084T1 (de)
DE (1) DE602005011763D1 (de)
WO (1) WO2005076050A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1615559B1 (de) * 2003-04-15 2012-08-22 Philips Intellectual Property & Standards GmbH Verfahren zur ermittlung der räumlichen verteilung magnetischer partikel sowie zusammensetzung zu deren gabe
DE102005017817A1 (de) * 2005-04-18 2006-10-26 Siemens Ag Verfahren und Vorrichtung zur Untersuchung eines biologischen Gewebes
JP2009502402A (ja) * 2005-08-01 2009-01-29 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 光学イメージング
JP2011022201A (ja) * 2009-07-13 2011-02-03 Jikei Univ 顕微鏡装置用の光源装置、及び光源装置付き観察試料載置具、並びに顕微鏡装置
EP3039477B1 (de) 2013-08-26 2021-10-20 S.D. Sight Diagnostics Ltd. Digitale mikroskopiesysteme, verfahren und computerprogrammprodukte
CN103575716A (zh) * 2013-11-15 2014-02-12 中国科学院长春应用化学研究所 磁场调控的超分辨荧光成像方法
EP3859425B1 (de) 2015-09-17 2024-04-17 S.D. Sight Diagnostics Ltd. Verfahren und vorrichtung zur detektion einer entität in einer körperprobe
WO2017168411A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Image processing device for identifying blood parasites
EP4177593A1 (de) 2016-05-11 2023-05-10 S.D. Sight Diagnostics Ltd. Probenträger für optische messungen
CN115266540B (zh) 2016-05-11 2025-11-28 思迪赛特诊断有限公司 对样品实施的光学测量
JP7214729B2 (ja) * 2017-11-14 2023-01-30 エス．ディー．サイト ダイアグノスティクス リミテッド 光学測定用試料収容器
DE102018206406C5 (de) * 2018-04-25 2025-05-15 Carl Zeiss Meditec Ag Mikroskopiesystem
US12498325B2 (en) 2019-10-22 2025-12-16 S.D. Sight Diagnostics Ltd. Accounting for errors in optical measurements
WO2021116959A1 (en) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium
JP7677972B2 (ja) 2019-12-12 2025-05-15 エス．ディー．サイト ダイアグノスティックス リミテッド カラー血液スミア画像の人工的な生成

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578167A (en) * 1982-09-28 1986-03-25 Biofusion, Inc. Cell fusion
US4676640A (en) * 1984-09-12 1987-06-30 Syntex (U.S.A.) Inc. Fluctuation analysis for enhanced particle detection
DE19508366C2 (de) * 1995-03-10 1998-01-29 Evotec Biosystems Gmbh Verfahren zum direkten Nachweisen weniger Nucleinsäurestränge
MY139225A (en) * 1998-02-26 2009-08-28 Anglo Operations Ltd Method and apparatus for separating particles
DE19903001A1 (de) * 1999-01-26 2000-08-24 Evotec Biosystems Ag Verfahren und Vorrichtung zur Detektion mikroskopisch kleiner Objekte
US6271660B1 (en) * 1999-06-11 2001-08-07 Mts Sytems Corporation Permanent multi-pole position magnet
US6437551B1 (en) * 1999-11-02 2002-08-20 The Regents Of The University Of California Microfabricated AC impedance sensor
EP1328894A4 (de) * 2000-08-25 2005-11-09 Amnis Corp Messung der geschwindigkeit kleiner beweglicher objekte, wie zum beispiel zellen
DE10103304A1 (de) * 2001-01-25 2002-08-01 Gnothis Holding Sa Ecublens Verfahren zur fluoreszenzspektroskopischen, insbesondere fluoreszenzkorrelationsspektroskopischen Untersuchung einer Messprobe sowie Einrichtung zur Durchführung desselben
US20020127144A1 (en) * 2001-03-08 2002-09-12 Mehta Shailesh P. Device for analyzing particles and method of use
CA2441366A1 (en) * 2001-03-24 2002-10-03 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
DE10151778A1 (de) * 2001-10-19 2003-05-08 Philips Corp Intellectual Pty Verfahren zur Ermittlung der räumlichen Verteilung magnetischer Partikel
JP4890242B2 (ja) * 2003-04-15 2012-03-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 検査エリアにおける状態変数の空間分解を決定する装置及び方法

Also Published As

Publication number Publication date
WO2005076050A1 (en) 2005-08-18
CN1918501A (zh) 2007-02-21
EP1716444A1 (de) 2006-11-02
US20070161075A1 (en) 2007-07-12
DE602005011763D1 (de) 2009-01-29
JP4804363B2 (ja) 2011-11-02
CN100526932C (zh) 2009-08-12
EP1716444B1 (de) 2008-12-17
JP2007522502A (ja) 2007-08-09

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