JP4749550B2 - アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体 - Google Patents

アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体 Download PDF

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Publication number
JP4749550B2
JP4749550B2 JP2000604054A JP2000604054A JP4749550B2 JP 4749550 B2 JP4749550 B2 JP 4749550B2 JP 2000604054 A JP2000604054 A JP 2000604054A JP 2000604054 A JP2000604054 A JP 2000604054A JP 4749550 B2 JP4749550 B2 JP 4749550B2
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JP
Japan
Prior art keywords
product
hydroxy
methoxy
alkyl
hydrogen
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Expired - Lifetime
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JP2000604054A
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Japanese (ja)
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JP2002539135A5 (enExample
JP2002539135A (ja
Inventor
ローゼン，フーベルト・ヤン・ヨーゼフ
レイセン，デイルク
フアン，デル・ローウ・ヤープ
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ナームローゼ・フエンノートチヤツプ・オルガノン
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Publication of JP2002539135A publication Critical patent/JP2002539135A/ja
Publication of JP2002539135A5 publication Critical patent/JP2002539135A5/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000604054A 1999-03-08 2000-03-02 アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体 Expired - Lifetime JP4749550B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99200665 1999-03-08
EP99200665.0 1999-03-08
PCT/EP2000/001755 WO2000053619A1 (en) 1999-03-08 2000-03-02 14.beta., 17-alpha-hydroxymethylandrostane derivatives as androgens

Publications (3)

Publication Number Publication Date
JP2002539135A JP2002539135A (ja) 2002-11-19
JP2002539135A5 JP2002539135A5 (enExample) 2007-05-10
JP4749550B2 true JP4749550B2 (ja) 2011-08-17

Family

ID=8239953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000604054A Expired - Lifetime JP4749550B2 (ja) 1999-03-08 2000-03-02 アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体

Country Status (11)

Country Link
US (1) US6881728B1 (enExample)
EP (1) EP1163259B1 (enExample)
JP (1) JP4749550B2 (enExample)
AR (1) AR022852A1 (enExample)
AT (1) ATE228143T1 (enExample)
AU (1) AU3162200A (enExample)
CA (1) CA2359218A1 (enExample)
CO (1) CO5150195A1 (enExample)
DE (1) DE60000826T2 (enExample)
PE (1) PE20001489A1 (enExample)
WO (1) WO2000053619A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287095B6 (sk) 1999-12-02 2009-12-07 N.V. Organon Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom
AU2492302A (en) 2000-12-11 2002-06-24 Akzo Nobel Nv Methylene steroids as novel androgens
DE10104327A1 (de) * 2001-01-24 2002-07-25 Schering Ag 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate
TWI221154B (en) * 2001-09-12 2004-09-21 Akzo Nobel Nv 17alpha-hydroxy-14beta-steroids with hormonal effect
PE20050677A1 (es) 2003-12-22 2005-10-04 Akzo Nobel Nv Esteroides con perfil androgenico y progestagenico mixto

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
JPS63216895A (ja) * 1987-01-23 1988-09-09 アクゾ・エヌ・ヴエー 新規な１１−アリールステロイド誘導体
WO1993015104A1 (en) * 1992-01-29 1993-08-05 Research Corporation Technologies, Inc. 20-substituted pregnene derivatives and their use as androgen synthesis inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002746A (en) * 1959-09-25 1977-01-11 Herchel Smith Synthesis of gon-4-enes
US6180682B1 (en) * 1999-01-26 2001-01-30 Virgil A. Place Buccal drug delivery system for use in male contraception

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
JPS63216895A (ja) * 1987-01-23 1988-09-09 アクゾ・エヌ・ヴエー 新規な１１−アリールステロイド誘導体
WO1993015104A1 (en) * 1992-01-29 1993-08-05 Research Corporation Technologies, Inc. 20-substituted pregnene derivatives and their use as androgen synthesis inhibitors

Also Published As

Publication number Publication date
PE20001489A1 (es) 2000-12-29
ATE228143T1 (de) 2002-12-15
JP2002539135A (ja) 2002-11-19
EP1163259B1 (en) 2002-11-20
US6881728B1 (en) 2005-04-19
CA2359218A1 (en) 2000-09-14
AU3162200A (en) 2000-09-28
CO5150195A1 (es) 2002-04-29
DE60000826T2 (de) 2003-04-10
AR022852A1 (es) 2002-09-04
DE60000826D1 (de) 2003-01-02
EP1163259A1 (en) 2001-12-19
WO2000053619A1 (en) 2000-09-14

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JP4749550B2 (ja) アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体
KR100730010B1 (ko) 신규 안드로겐
US20040059140A1 (en) 14(15)-unsaturated 15- and/or 16-substituted androgens with mixed androgen-progrestational profile
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AU2002224923A1 (en) Methylene steroids as novel androgens

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