JP4718836B2 - 前立腺疾病を治療するためのヨクイニン油軟カプセル剤 - Google Patents
前立腺疾病を治療するためのヨクイニン油軟カプセル剤 Download PDFInfo
- Publication number
- JP4718836B2 JP4718836B2 JP2004538657A JP2004538657A JP4718836B2 JP 4718836 B2 JP4718836 B2 JP 4718836B2 JP 2004538657 A JP2004538657 A JP 2004538657A JP 2004538657 A JP2004538657 A JP 2004538657A JP 4718836 B2 JP4718836 B2 JP 4718836B2
- Authority
- JP
- Japan
- Prior art keywords
- yokuinin
- neutral lipid
- soft capsule
- prostate cancer
- treating prostate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN02137311.6 | 2002-09-28 | ||
| CNA021373116A CN1485072A (zh) | 2002-09-28 | 2002-09-28 | 治疗前列腺疾病的薏苡仁油软胶囊及其应用 |
| PCT/CN2003/000803 WO2004028549A1 (en) | 2002-09-28 | 2003-09-22 | A coixenolide capsules for treating prostate disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010237581A Division JP2011016852A (ja) | 2002-09-28 | 2010-10-22 | 前立腺疾病を治療するためのヨクイニン油軟カプセル剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006502193A JP2006502193A (ja) | 2006-01-19 |
| JP2006502193A5 JP2006502193A5 (enExample) | 2006-10-19 |
| JP4718836B2 true JP4718836B2 (ja) | 2011-07-06 |
Family
ID=32034732
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004538657A Expired - Fee Related JP4718836B2 (ja) | 2002-09-28 | 2003-09-22 | 前立腺疾病を治療するためのヨクイニン油軟カプセル剤 |
| JP2010237581A Pending JP2011016852A (ja) | 2002-09-28 | 2010-10-22 | 前立腺疾病を治療するためのヨクイニン油軟カプセル剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010237581A Pending JP2011016852A (ja) | 2002-09-28 | 2010-10-22 | 前立腺疾病を治療するためのヨクイニン油軟カプセル剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8299121B2 (enExample) |
| EP (1) | EP1576959B1 (enExample) |
| JP (2) | JP4718836B2 (enExample) |
| CN (2) | CN1485072A (enExample) |
| AT (1) | ATE493140T1 (enExample) |
| AU (1) | AU2003272841A1 (enExample) |
| DE (1) | DE60335575D1 (enExample) |
| DK (1) | DK1576959T3 (enExample) |
| ES (1) | ES2358420T3 (enExample) |
| RU (1) | RU2296581C2 (enExample) |
| WO (1) | WO2004028549A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9492493B2 (en) * | 2003-09-22 | 2016-11-15 | Dapeng Li | Softgel of NLKJ for treating prostate diseases |
| JP4703649B2 (ja) | 2004-07-30 | 2011-06-15 | エグゼリクシス, インコーポレイテッド | 薬学的因子としてのピロール誘導体 |
| CN102511824A (zh) * | 2011-12-20 | 2012-06-27 | 金利油脂(苏州)有限公司 | 一种抗突变抗肿瘤的功能性食品 |
| CN105250804A (zh) * | 2014-07-18 | 2016-01-20 | 浙江康莱特集团有限公司 | 含有11种甘油三酯的薏苡仁油、制剂及其应用 |
| CN105254498B (zh) * | 2014-07-18 | 2017-11-21 | 浙江康莱特药业有限公司 | 化合物1,3‑二油酸‑2‑亚油酸甘油酯、制剂、制备方法及其应用 |
| US9585929B2 (en) * | 2014-07-18 | 2017-03-07 | Zhejiang Kanglaite Group Co., Ltd. | Coix seed oil containing 13 glycerides, and pharmaceutical preparation and use thereof |
| CN105311486A (zh) * | 2014-07-18 | 2016-02-10 | 浙江康莱特集团有限公司 | 含有16种甘油酯的薏苡仁油、制剂及其应用 |
| US9884037B2 (en) * | 2014-07-18 | 2018-02-06 | Zhejiang Kanglaite Group Co., Ltd. | Pharmaceutical composition containing 8 triglycerides, and preparations and use thereof |
| CN104173824B (zh) * | 2014-07-18 | 2017-02-15 | 浙江康莱特集团有限公司 | 含有8种甘油三酯的薏苡仁油、制剂及其应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5731604A (en) * | 1980-07-31 | 1982-02-20 | Okayasu Shoten:Kk | Skin cosmetic |
| JPS58213719A (ja) * | 1982-06-02 | 1983-12-12 | Yasuo Araki | 薬物的活性剤 |
| JPS58210022A (ja) * | 1982-06-02 | 1983-12-07 | Yasuo Araki | ハトムギ有効成分の純品精出法及び定量検定法 |
| JPH01186815A (ja) * | 1988-01-21 | 1989-07-26 | Tokai Kapuseru Kk | 軟カプセル剤およびその製造法 |
| JPH02240019A (ja) * | 1989-03-13 | 1990-09-25 | Daicel Chem Ind Ltd | 抗発癌プロモーター |
| JP2783848B2 (ja) * | 1989-07-04 | 1998-08-06 | 晟 八木 | 新規ホスファチジルコリンカルシウムとその製法 |
| CN1031261C (zh) * | 1991-10-21 | 1996-03-13 | 中国科学院大连化学物理研究所 | 一种薏苡仁酯的提取方法 |
| JPH07503010A (ja) * | 1992-01-06 | 1995-03-30 | ヘルス・メインテナンス・プログラムズ,インコーポレイテッド | 薬学活性酸化防止剤含有組成物並びに該組成物を使用する血管形成後の再狭窄予防および治療方法 |
| RU2123853C1 (ru) * | 1992-09-16 | 1998-12-27 | Пенг Ли Да | Нейтральные липиды из зерен коикса nlkj, способ их получения, фармацевтическая композиция на их основе, нейтральные липиды для применения в качестве лекарственного средства |
| CN1070680A (zh) * | 1992-09-17 | 1993-04-07 | 李大鹏 | 薏苡仁中性油脂提取方法 |
| PH30249A (en) * | 1992-09-16 | 1997-02-05 | Zhejiang Provincial Hospital O | Neutral lipids from endosperm of job's tears |
| CN1029662C (zh) | 1992-09-17 | 1995-09-06 | 李大鹏 | 薏苡仁中性油脂及其提取方法 |
| JPH06247858A (ja) * | 1993-02-23 | 1994-09-06 | Fujimoto Seiyaku Kk | 慢性腎不全における抗骨異栄養症剤 |
| JPH07115942A (ja) * | 1993-08-09 | 1995-05-09 | Sanji Kumai | 生薬オリゴドリンク及び生薬オリゴゼリーの製造法 |
| CN1064244C (zh) * | 1993-11-09 | 2001-04-11 | 中国科学院大连化学物理研究所 | 中药薏苡仁提取物在制备治疗红班角化症、鳞状毛囊角化症、红皮症药物中的应用 |
| US20010002269A1 (en) * | 1997-05-06 | 2001-05-31 | Zhao Iris Ginron | Multi-phase food & beverage |
| CN1075378C (zh) * | 1997-09-30 | 2001-11-28 | 陈金义 | 一种抗肿瘤的中药乳剂及其制备方法 |
| RU2178660C2 (ru) * | 1998-07-31 | 2002-01-27 | Закрытое акционерное общество "Эвалар" | Лечебно-оздоровительная биологически активная добавка к пище "милона" и способ ее получения |
| EP1102593B1 (en) * | 1998-08-03 | 2007-11-14 | Ronald E. Wheeler | Prostate formula |
| US6565874B1 (en) * | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| RU2174003C1 (ru) * | 2000-04-17 | 2001-09-27 | Зарубин Александр Андреевич | Фармацевтическая лечебная композиция, способ лечебного и лечебно-профилактического ее применения |
| JP3983003B2 (ja) * | 2001-03-15 | 2007-09-26 | 株式会社ファンケル | グルタチオン増強用組成物 |
| US20030236301A1 (en) * | 2001-12-19 | 2003-12-25 | Bob Sanders | Liposomal delivery of vitamin E based compounds |
| CN1440782A (zh) * | 2003-03-28 | 2003-09-10 | 沈阳药科大学 | 一种含有薏苡仁油及鸦胆子油复合纳米乳剂的制备工艺及配方 |
-
2002
- 2002-09-28 CN CNA021373116A patent/CN1485072A/zh active Pending
-
2003
- 2003-09-22 EP EP03753221A patent/EP1576959B1/en not_active Expired - Lifetime
- 2003-09-22 ES ES03753221T patent/ES2358420T3/es not_active Expired - Lifetime
- 2003-09-22 RU RU2005112775/15A patent/RU2296581C2/ru not_active IP Right Cessation
- 2003-09-22 AU AU2003272841A patent/AU2003272841A1/en not_active Abandoned
- 2003-09-22 WO PCT/CN2003/000803 patent/WO2004028549A1/zh not_active Ceased
- 2003-09-22 AT AT03753221T patent/ATE493140T1/de active
- 2003-09-22 DE DE60335575T patent/DE60335575D1/de not_active Expired - Lifetime
- 2003-09-22 JP JP2004538657A patent/JP4718836B2/ja not_active Expired - Fee Related
- 2003-09-22 CN CNB038227711A patent/CN1301128C/zh not_active Expired - Fee Related
- 2003-09-22 DK DK03753221.5T patent/DK1576959T3/da active
-
2005
- 2005-03-28 US US11/099,780 patent/US8299121B2/en not_active Expired - Fee Related
-
2010
- 2010-10-22 JP JP2010237581A patent/JP2011016852A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1576959A4 (en) | 2008-04-23 |
| DE60335575D1 (de) | 2011-02-10 |
| EP1576959A1 (en) | 2005-09-21 |
| CN1301128C (zh) | 2007-02-21 |
| DK1576959T3 (da) | 2011-03-28 |
| US20050222249A1 (en) | 2005-10-06 |
| ES2358420T3 (es) | 2011-05-10 |
| CN1485072A (zh) | 2004-03-31 |
| RU2296581C2 (ru) | 2007-04-10 |
| AU2003272841A1 (en) | 2004-04-19 |
| US20100137427A9 (en) | 2010-06-03 |
| US8299121B2 (en) | 2012-10-30 |
| ATE493140T1 (de) | 2011-01-15 |
| RU2005112775A (ru) | 2006-11-10 |
| WO2004028549A1 (en) | 2004-04-08 |
| JP2006502193A (ja) | 2006-01-19 |
| CN1684697A (zh) | 2005-10-19 |
| EP1576959B1 (en) | 2010-12-29 |
| JP2011016852A (ja) | 2011-01-27 |
| HK1082426A1 (en) | 2006-06-09 |
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