JP4647909B2 - 大うつ病性障害の治療における(11β,17β)−11−(1,3−ベンゾジオキソール−5−イル)−17−ヒドロキシ−17−(1−プロピニル)エストラ−4,9−ジエン−3−オンの使用 - Google Patents

大うつ病性障害の治療における(11β,17β)−11−(1,3−ベンゾジオキソール−5−イル)−17−ヒドロキシ−17−(1−プロピニル)エストラ−4,9−ジエン−3−オンの使用 Download PDF

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JP4647909B2
JP4647909B2 JP2003539697A JP2003539697A JP4647909B2 JP 4647909 B2 JP4647909 B2 JP 4647909B2 JP 2003539697 A JP2003539697 A JP 2003539697A JP 2003539697 A JP2003539697 A JP 2003539697A JP 4647909 B2 JP4647909 B2 JP 4647909B2
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treatment
patients
propynyl
hydroxy
benzodioxol
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JP2005521637A5 (https=
JP2005521637A (ja
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セネフ,コルネリス
ペータース,ベルナルドス・ウエイナンド・マテイス・マリー
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ナームローゼ・フエンノートチヤツプ・オルガノン
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2003539697A 2001-10-26 2002-10-21 大うつ病性障害の治療における(11β,17β)−11−(1,3−ベンゾジオキソール−5−イル)−17−ヒドロキシ−17−(1−プロピニル)エストラ−4,9−ジエン−3−オンの使用 Expired - Fee Related JP4647909B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01204072 2001-10-26
PCT/EP2002/011732 WO2003037354A1 (en) 2001-10-26 2002-10-21 USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER

Publications (3)

Publication Number Publication Date
JP2005521637A JP2005521637A (ja) 2005-07-21
JP2005521637A5 JP2005521637A5 (https=) 2006-01-05
JP4647909B2 true JP4647909B2 (ja) 2011-03-09

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JP2003539697A Expired - Fee Related JP4647909B2 (ja) 2001-10-26 2002-10-21 大うつ病性障害の治療における(11β,17β)−11−(1,3−ベンゾジオキソール−5−イル)−17−ヒドロキシ−17−(1−プロピニル)エストラ−4,9−ジエン−3−オンの使用

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Country Link
US (1) US20040266863A1 (https=)
EP (2) EP1652526B1 (https=)
JP (1) JP4647909B2 (https=)
KR (1) KR20050038580A (https=)
CN (1) CN100531738C (https=)
AT (2) ATE317700T1 (https=)
AU (1) AU2002348996B2 (https=)
BR (1) BR0213466A (https=)
CA (1) CA2463446C (https=)
CY (1) CY1110173T1 (https=)
DE (2) DE60230936D1 (https=)
DK (1) DK1652526T3 (https=)
EC (1) ECSP045080A (https=)
ES (1) ES2319563T3 (https=)
HR (1) HRP20040370B1 (https=)
HU (1) HUP0500070A3 (https=)
IL (2) IL161248A0 (https=)
IS (1) IS2702B (https=)
MX (1) MXPA04003781A (https=)
NO (1) NO332978B1 (https=)
NZ (1) NZ532429A (https=)
PL (1) PL206687B1 (https=)
PT (1) PT1652526E (https=)
RU (1) RU2302245C2 (https=)
WO (1) WO2003037354A1 (https=)
ZA (1) ZA200403088B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050080061A1 (en) * 2003-07-23 2005-04-14 Corcept Therapeutics, Inc. Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
EP2292269A3 (en) * 2004-11-19 2011-08-10 N.V. Organon Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
AU2011236053B2 (en) * 2004-11-19 2014-06-26 Merck Sharpe & Dohme B.V. Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
JP2009535430A (ja) * 2006-05-02 2009-10-01 コーセプト セラピューティクス, インコーポレイテッド Il−2を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターiiアンタゴニストの使用
EP2671086B1 (en) * 2011-02-03 2018-04-25 Pop Test Oncology LLC System and method for diagnosis and treatment
US20120263660A1 (en) * 2011-04-18 2012-10-18 Pop Test Cortisol Llc Hair Loss Treatment
US8986677B2 (en) * 2012-07-30 2015-03-24 Pop Test Cortisol Llc Therapeutic compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814333A (en) * 1987-07-28 1989-03-21 The Trustees Of Dartmouth College Method for treatment of hypercortisolemic, depressed patients
DE4447401A1 (de) * 1994-12-23 1996-07-04 Schering Ag 14,17-C¶2¶-überbrückte Steroide
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) * 1997-06-30 1999-01-28 Forschungszentrum Juelich Gmbh Magnetflußsensor mit ringförmiger Sonde
ATE332696T1 (de) * 1997-10-06 2006-08-15 Univ Leland Stanford Junior Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
CN1820756A (zh) * 2001-03-23 2006-08-23 科塞普特治疗公司 使用糖皮质激素受体特效拮抗剂治疗压力症的方法
DE60238671D1 (de) * 2001-05-04 2011-02-03 Corcept Therapeutics Inc Verwendung von glucocorticoid-rezeptor-spezifischen antagonisten zur behandlung von delirium
IL160649A0 (en) * 2001-08-31 2004-07-25 Corcept Therapeutics Inc Methods for inhibiting cognitive deterioration in adults with down syndrome

Also Published As

Publication number Publication date
CA2463446C (en) 2010-02-23
EP1441739B1 (en) 2006-02-15
IL161248A (en) 2010-12-30
NO332978B1 (no) 2013-02-11
EP1652526A2 (en) 2006-05-03
US20040266863A1 (en) 2004-12-30
WO2003037354A1 (en) 2003-05-08
EP1652526A3 (en) 2006-08-02
DE60230936D1 (de) 2009-03-05
HUP0500070A2 (hu) 2005-04-28
ECSP045080A (es) 2004-06-28
PT1652526E (pt) 2009-02-06
ZA200403088B (en) 2005-01-24
NO20041651L (no) 2004-04-23
RU2302245C2 (ru) 2007-07-10
CN100531738C (zh) 2009-08-26
BR0213466A (pt) 2004-11-09
IS7204A (is) 2004-03-31
ATE420649T1 (de) 2009-01-15
CA2463446A1 (en) 2003-05-08
CY1110173T1 (el) 2015-01-14
JP2005521637A (ja) 2005-07-21
HRP20040370A2 (en) 2004-08-31
EP1652526B1 (en) 2009-01-14
KR20050038580A (ko) 2005-04-27
HUP0500070A3 (en) 2012-09-28
PL206687B1 (pl) 2010-09-30
HRP20040370B1 (hr) 2012-09-30
CN1582153A (zh) 2005-02-16
NZ532429A (en) 2004-10-29
ATE317700T1 (de) 2006-03-15
IS2702B (is) 2010-11-15
DK1652526T3 (da) 2009-05-18
ES2319563T3 (es) 2009-05-08
IL161248A0 (en) 2004-09-27
HK1087357A1 (en) 2006-10-13
EP1441739A1 (en) 2004-08-04
PL369261A1 (en) 2005-04-18
AU2002348996B2 (en) 2008-06-05
DE60209248D1 (de) 2006-04-20
RU2004116082A (ru) 2005-05-10
MXPA04003781A (es) 2004-07-30

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