JP4621311B2 - 抗菌性組成物 - Google Patents

抗菌性組成物 Download PDF

Info

Publication number
JP4621311B2
JP4621311B2 JP26120598A JP26120598A JP4621311B2 JP 4621311 B2 JP4621311 B2 JP 4621311B2 JP 26120598 A JP26120598 A JP 26120598A JP 26120598 A JP26120598 A JP 26120598A JP 4621311 B2 JP4621311 B2 JP 4621311B2
Authority
JP
Japan
Prior art keywords
oxo
formula
hydroxy
pharmaceutically acceptable
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP26120598A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11140087A (ja
JPH11140087A5 (enExample
Inventor
ペーター・アンゲールン
イングリット・ハインツ−クラウス
マルコルム・パージェ
ハンス・ゲー・エフ・リヒター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basilea Pharmaceutica AG
Original Assignee
Basilea Pharmaceutica AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica AG filed Critical Basilea Pharmaceutica AG
Publication of JPH11140087A publication Critical patent/JPH11140087A/ja
Publication of JPH11140087A5 publication Critical patent/JPH11140087A5/ja
Application granted granted Critical
Publication of JP4621311B2 publication Critical patent/JP4621311B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
JP26120598A 1997-09-15 1998-09-16 抗菌性組成物 Expired - Fee Related JP4621311B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97115997 1997-09-15
EP97115997.5 1997-09-15

Publications (3)

Publication Number Publication Date
JPH11140087A JPH11140087A (ja) 1999-05-25
JPH11140087A5 JPH11140087A5 (enExample) 2005-11-04
JP4621311B2 true JP4621311B2 (ja) 2011-01-26

Family

ID=8227350

Family Applications (1)

Application Number Title Priority Date Filing Date
JP26120598A Expired - Fee Related JP4621311B2 (ja) 1997-09-15 1998-09-16 抗菌性組成物

Country Status (16)

Country Link
US (1) US6150350A (enExample)
EP (1) EP0911030B1 (enExample)
JP (1) JP4621311B2 (enExample)
KR (1) KR100630012B1 (enExample)
CN (1) CN1186021C (enExample)
AR (1) AR013490A1 (enExample)
AT (1) ATE292994T1 (enExample)
AU (1) AU747285B2 (enExample)
BR (1) BR9803443A (enExample)
CA (1) CA2247232C (enExample)
DE (1) DE69829720T2 (enExample)
DK (1) DK0911030T3 (enExample)
ES (1) ES2241084T3 (enExample)
PT (1) PT911030E (enExample)
TR (1) TR199801835A2 (enExample)
ZA (1) ZA988399B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2335288A1 (en) * 1998-06-22 1999-12-29 F. Hoffmann-La Roche Ag Propenyl cephalosporin derivatives
WO2000032605A1 (en) * 1998-12-03 2000-06-08 F. Hoffmann-La Roche Ag Bi-pyrrolidinylvinl (carba) cephalosporins
JP4583559B2 (ja) * 2000-07-24 2010-11-17 栄研化学株式会社 Ｍｒｓａスクリーニング用培地
CN100384857C (zh) * 2003-11-28 2008-04-30 浙江永宁制药厂 耐β-内酰胺酶的头孢菌素酯化合物及其盐
CN112608369A (zh) * 2020-12-30 2021-04-06 中国海洋大学 一种具有抑菌活性的细菌素及其生产方法及用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0347122A (ja) * 1989-02-21 1991-02-28 Banyu Pharmaceut Co Ltd 抗菌性組成物
DE69019395D1 (de) * 1989-02-21 1995-06-22 Banyu Pharma Co Ltd Zusammensetzung gegen Mikroben.
GB9019743D0 (en) * 1990-09-10 1990-10-24 Beecham Group Plc Novel compounds
KR100214288B1 (ko) * 1993-04-16 1999-08-02 성재갑 안개서림 방지용 내마모성 피복조성물 및 이를 도포한 합성수지 성형품
EP0620225B1 (en) * 1993-04-16 2002-11-13 Basilea Pharmaceutica AG Cephalosporin derivatives
TW383308B (en) * 1993-08-24 2000-03-01 Hoffmann La Roche 2-beta-alkenyl penam sulfones as beta-lactamase inhibitors
US5464616A (en) * 1994-08-04 1995-11-07 Synphar Laboratories, Ind. 6β-substituted penicillanic acids as beta-lactamase inhibitors
WO1996026943A1 (en) * 1995-02-27 1996-09-06 F.Hoffmann-La Roche Ag Derivatives of 3-pyrrolidylidene-2-one-cephalosporines
DK0841339T3 (da) * 1996-11-06 2007-07-02 Basilea Pharmaceutica Ag Vinylpyrrolidinon-cephalosporinderivater

Also Published As

Publication number Publication date
KR19990029769A (ko) 1999-04-26
BR9803443A (pt) 2000-02-08
CA2247232C (en) 2007-08-28
JPH11140087A (ja) 1999-05-25
US6150350A (en) 2000-11-21
DK0911030T3 (da) 2005-08-01
EP0911030A3 (en) 1999-10-13
TR199801835A3 (tr) 1999-04-21
CA2247232A1 (en) 1999-03-15
KR100630012B1 (ko) 2006-11-30
TR199801835A2 (xx) 1999-04-21
CN1186021C (zh) 2005-01-26
AU747285B2 (en) 2002-05-16
DE69829720T2 (de) 2006-03-09
ATE292994T1 (de) 2005-04-15
AU8425198A (en) 1999-04-01
PT911030E (pt) 2005-08-31
CN1216246A (zh) 1999-05-12
AR013490A1 (es) 2000-12-27
EP0911030B1 (en) 2005-04-13
DE69829720D1 (de) 2005-05-19
EP0911030A2 (en) 1999-04-28
ES2241084T3 (es) 2005-10-16
ZA988399B (en) 1999-03-15

Similar Documents

Publication Publication Date Title
EP0849269B9 (en) Vinyl pyrrolidine cephalosporins with basic substituents
EP0620225B1 (en) Cephalosporin derivatives
JP3065289B2 (ja) ビニルピロリジノンセファロスポリン誘導体類
CY1182A (en) F 7-2-2-amino-4-hetrocyclylthiomethyl-cephems
JP4621311B2 (ja) 抗菌性組成物
KR100414336B1 (ko) 프로페닐 세팔로스포린 유도체
MXPA98007489A (en) Antimicrobi composition
JP2000503654A (ja) イソオキサセフェム誘導体
JPH10101670A (ja) １−カルバ−（デチア）−セファロスポリン誘導体
MXPA97008525A (en) Derivatives of vinilpirrolidinon-cefalospor
HK1012857A (en) Vinyl pyrrolidine cephalosporins with basic substituents
HK1010541A (en) Vinylpyrrolidinon cephalosporin derivatives
MXPA00012689A (en) Propenyl cephalosporin derivatives
EP0098615A1 (en) 1-Oxadethiacephalosporin compound and antibacterial agent containing the same
HRP970588A2 (en) Vinylpyrrolidinon cephalosporin derivatives

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050811

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050811

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090825

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091120

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091126

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091221

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091225

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100122

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100127

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100224

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100323

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100622

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100625

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100722

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100727

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100820

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20101019

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20101101

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131105

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees