JP4612990B2 - ヒスタミン−３受容体リガンドとしての新規アミンおよびそれらの治療的適用 - Google Patents

ヒスタミン−３受容体リガンドとしての新規アミンおよびそれらの治療的適用 Download PDF

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JP4612990B2
JP4612990B2 JP2002573767A JP2002573767A JP4612990B2 JP 4612990 B2 JP4612990 B2 JP 4612990B2 JP 2002573767 A JP2002573767 A JP 2002573767A JP 2002573767 A JP2002573767 A JP 2002573767A JP 4612990 B2 JP4612990 B2 JP 4612990B2
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Prior art keywords
ethyl
benzofuran
methyl
pyrrolidinyl
pyrrolidin
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Expired - Fee Related
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Japanese (ja)
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JP2005500986A5 (enExample
JP2005500986A (ja
Inventor
コワート，マーロン・デイー
ベンナニ，ユセフ・エル
フアギー，ラミン
グフエサー，グレゴリー・エイ
ブラツク，ローレンス・エイ
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Abbott Laboratories
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Abbott Laboratories
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Priority claimed from US09/810,648 external-priority patent/US20020177589A1/en
Priority claimed from US10/044,495 external-priority patent/US20020183309A1/en
Priority claimed from US10/081,207 external-priority patent/US6969730B2/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2005500986A publication Critical patent/JP2005500986A/ja
Publication of JP2005500986A5 publication Critical patent/JP2005500986A5/ja
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JP2002573767A 2001-03-16 2002-03-11 ヒスタミン−３受容体リガンドとしての新規アミンおよびそれらの治療的適用 Expired - Fee Related JP4612990B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/810,648 US20020177589A1 (en) 2001-03-16 2001-03-16 Novel amines as histamine-3 receptor ligands and their therapeutic applications
US10/044,495 US20020183309A1 (en) 2001-03-16 2002-01-11 Novel amines as histamine-3 receptor ligands and their therapeutic applications
US10/081,207 US6969730B2 (en) 2001-03-16 2002-02-25 Amines as histamine-3 receptor ligands and their therapeutic applications
PCT/US2002/007107 WO2002074758A2 (en) 2001-03-16 2002-03-11 Novel amines as histamine-3 receptor ligands and their therapeutic applications

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JP2005500986A JP2005500986A (ja) 2005-01-13
JP2005500986A5 JP2005500986A5 (enExample) 2005-12-22
JP4612990B2 true JP4612990B2 (ja) 2011-01-12

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EP (2) EP1370546A2 (enExample)
JP (1) JP4612990B2 (enExample)
AR (1) AR035783A1 (enExample)
BR (1) BR0205829A (enExample)
CA (1) CA2440238C (enExample)
MX (1) MXPA03008319A (enExample)
WO (1) WO2002074758A2 (enExample)

Families Citing this family (40)

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Publication number Priority date Publication date Assignee Title
US7314937B2 (en) 2002-03-21 2008-01-01 Eli Lilly And Company Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
US6822101B2 (en) 2002-09-16 2004-11-23 Abbott Laboratories Process for preparing amine-substituted benzofurans
CA2765093A1 (en) * 2002-11-12 2004-05-27 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
US7244852B2 (en) 2003-02-27 2007-07-17 Abbott Laboratories Process for preparing 2-methylpyrrolidine and specific enantiomers thereof
JP4736043B2 (ja) 2003-03-14 2011-07-27 小野薬品工業株式会社 含窒素複素環誘導体およびそれらを有効成分とする薬剤
JPWO2004089410A1 (ja) * 2003-04-03 2006-07-06 協和醗酵工業株式会社 神経因性疼痛の予防及び／または治療剤
US7094790B2 (en) 2003-05-07 2006-08-22 Abbott Laboratories Fused bicyclic-substituted amines as histamine-3 receptor ligands
MXPA05011942A (es) * 2003-05-07 2006-02-02 Abbott Lab Aminas sustituidas con biciclico fundido, como ligandos del receptor de histamina-3.
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