JP4607875B2 - 生理活性分子間の結合を決定するための磁性粒子の使用 - Google Patents

生理活性分子間の結合を決定するための磁性粒子の使用 Download PDF

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Publication number
JP4607875B2
JP4607875B2 JP2006521713A JP2006521713A JP4607875B2 JP 4607875 B2 JP4607875 B2 JP 4607875B2 JP 2006521713 A JP2006521713 A JP 2006521713A JP 2006521713 A JP2006521713 A JP 2006521713A JP 4607875 B2 JP4607875 B2 JP 4607875B2
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Prior art keywords
magnetic
beads
bead
particles
bound
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JP2007500346A5 (https=
JP2007500346A (ja
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メッノ ダヴリュ ジェイ プリンス
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Koninklijke Philips NV
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Koninklijke Philips NV
Koninklijke Philips Electronics NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2006521713A 2003-07-30 2004-07-14 生理活性分子間の結合を決定するための磁性粒子の使用 Expired - Fee Related JP4607875B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03102352 2003-07-30
PCT/IB2004/051213 WO2005010527A1 (en) 2003-07-30 2004-07-14 Use of magnetic particles for determining binding between bioactive molecules

Publications (3)

Publication Number Publication Date
JP2007500346A JP2007500346A (ja) 2007-01-11
JP2007500346A5 JP2007500346A5 (https=) 2007-08-30
JP4607875B2 true JP4607875B2 (ja) 2011-01-05

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JP2006521713A Expired - Fee Related JP4607875B2 (ja) 2003-07-30 2004-07-14 生理活性分子間の結合を決定するための磁性粒子の使用

Country Status (6)

Country Link
US (1) US20060205093A1 (https=)
EP (1) EP1651960A1 (https=)
JP (1) JP4607875B2 (https=)
KR (1) KR20060052889A (https=)
CN (1) CN1829916B (https=)
WO (1) WO2005010527A1 (https=)

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CN102216780A (zh) * 2008-11-19 2011-10-12 皇家飞利浦电子股份有限公司 用于致动磁性粒子的生物传感器系统
US20120208296A1 (en) * 2009-08-19 2012-08-16 Koninklijke Philips Electronics N.V. Detection of different target components by cluster formation
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Also Published As

Publication number Publication date
US20060205093A1 (en) 2006-09-14
WO2005010527A1 (en) 2005-02-03
CN1829916B (zh) 2010-09-29
JP2007500346A (ja) 2007-01-11
KR20060052889A (ko) 2006-05-19
CN1829916A (zh) 2006-09-06
EP1651960A1 (en) 2006-05-03

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