CN1829916B - 用于确定生物活性分子之间结合的磁性粒子的使用 - Google Patents

用于确定生物活性分子之间结合的磁性粒子的使用 Download PDF

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Publication number
CN1829916B
CN1829916B CN2004800221615A CN200480022161A CN1829916B CN 1829916 B CN1829916 B CN 1829916B CN 2004800221615 A CN2004800221615 A CN 2004800221615A CN 200480022161 A CN200480022161 A CN 200480022161A CN 1829916 B CN1829916 B CN 1829916B
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magnetic
particle
pearl
molecule
microbial
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CN2004800221615A
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CN1829916A (zh
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M·W·J·普林斯
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN2004800221615A 2003-07-30 2004-07-14 用于确定生物活性分子之间结合的磁性粒子的使用 Expired - Fee Related CN1829916B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03102352.6 2003-07-30
EP03102352 2003-07-30
PCT/IB2004/051213 WO2005010527A1 (en) 2003-07-30 2004-07-14 Use of magnetic particles for determining binding between bioactive molecules

Publications (2)

Publication Number Publication Date
CN1829916A CN1829916A (zh) 2006-09-06
CN1829916B true CN1829916B (zh) 2010-09-29

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CN2004800221615A Expired - Fee Related CN1829916B (zh) 2003-07-30 2004-07-14 用于确定生物活性分子之间结合的磁性粒子的使用

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Country Link
US (1) US20060205093A1 (https=)
EP (1) EP1651960A1 (https=)
JP (1) JP4607875B2 (https=)
KR (1) KR20060052889A (https=)
CN (1) CN1829916B (https=)
WO (1) WO2005010527A1 (https=)

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US9658178B2 (en) 2012-09-28 2017-05-23 General Electric Company Sensor systems for measuring an interface level in a multi-phase fluid composition
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CN101558313A (zh) * 2006-12-12 2009-10-14 皇家飞利浦电子股份有限公司 通过机械地移动至少一个磁体来将磁力应用到生物传感器表面的系统
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US8822227B2 (en) * 2008-02-06 2014-09-02 Koninklijke Philips N.V. Magnetic bead actuation using feedback for FTIR biosensor
US8053250B2 (en) * 2008-06-27 2011-11-08 Rex Chin-Yih Hong Method and system for suppressing bindings on magnetic particles
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CN102216780A (zh) * 2008-11-19 2011-10-12 皇家飞利浦电子股份有限公司 用于致动磁性粒子的生物传感器系统
WO2011021142A1 (en) * 2009-08-19 2011-02-24 Koninklijke Philips Electronics N.V. Detection of different target components by cluster formation
DE102010013900B4 (de) * 2010-04-01 2013-01-03 Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür
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CN107356758B (zh) * 2017-08-25 2019-11-22 李红俊 一种肺癌检测试剂盒及其使用方法
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CN111693691B (zh) * 2019-03-14 2023-09-05 天津华科泰生物技术有限公司 一种基于卟啉结构的聚合物标签
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Publication number Publication date
WO2005010527A1 (en) 2005-02-03
KR20060052889A (ko) 2006-05-19
JP2007500346A (ja) 2007-01-11
EP1651960A1 (en) 2006-05-03
CN1829916A (zh) 2006-09-06
JP4607875B2 (ja) 2011-01-05
US20060205093A1 (en) 2006-09-14

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