JP4558949B2 - 細胞活性アッセイ装置およびその製造方法、ならびにその使用方法 - Google Patents

細胞活性アッセイ装置およびその製造方法、ならびにその使用方法 Download PDF

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JP4558949B2
JP4558949B2 JP2000605716A JP2000605716A JP4558949B2 JP 4558949 B2 JP4558949 B2 JP 4558949B2 JP 2000605716 A JP2000605716 A JP 2000605716A JP 2000605716 A JP2000605716 A JP 2000605716A JP 4558949 B2 JP4558949 B2 JP 4558949B2
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membrane
angle
film
electromagnetic radiation
cell activity
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JP2002538816A5 (enExample
JP2002538816A (ja
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リチャード，エイチ．，ジュニア．グッドウィン
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ニューロ プローブ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000605716A 1999-03-18 2000-03-06 細胞活性アッセイ装置およびその製造方法、ならびにその使用方法 Expired - Lifetime JP4558949B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/271,765 US6329164B1 (en) 1999-03-18 1999-03-18 Method for using a cell activity assay apparatus
US09/271,765 1999-03-18
PCT/US2000/005760 WO2000055298A1 (en) 1999-03-18 2000-03-06 Cell activity assay apparatus and methods for making and using same

Publications (3)

Publication Number Publication Date
JP2002538816A JP2002538816A (ja) 2002-11-19
JP2002538816A5 JP2002538816A5 (enExample) 2007-05-31
JP4558949B2 true JP4558949B2 (ja) 2010-10-06

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JP2000605716A Expired - Lifetime JP4558949B2 (ja) 1999-03-18 2000-03-06 細胞活性アッセイ装置およびその製造方法、ならびにその使用方法

Country Status (7)

Country Link
US (3) US6329164B1 (enExample)
EP (1) EP1165745B1 (enExample)
JP (1) JP4558949B2 (enExample)
AT (1) ATE327315T1 (enExample)
AU (1) AU3725400A (enExample)
DE (1) DE60028192T2 (enExample)
WO (1) WO2000055298A1 (enExample)

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US6329164B1 (en) * 1999-03-18 2001-12-11 Neuro Probe, Incorporated Method for using a cell activity assay apparatus
US6864065B2 (en) * 2000-11-08 2005-03-08 Surface Logix, Inc. Assays for monitoring cell motility in real-time
US6844184B2 (en) * 2000-11-08 2005-01-18 Surface Logix, Inc. Device for arraying biomolecules and for monitoring cell motility in real-time
US7326563B2 (en) 2000-11-08 2008-02-05 Surface Logix, Inc. Device and method for monitoring leukocyte migration
US6699665B1 (en) * 2000-11-08 2004-03-02 Surface Logix, Inc. Multiple array system for integrating bioarrays
US6893851B2 (en) 2000-11-08 2005-05-17 Surface Logix, Inc. Method for arraying biomolecules and for monitoring cell motility in real-time
US7033819B2 (en) 2000-11-08 2006-04-25 Surface Logix, Inc. System for monitoring cell motility in real-time
US7374906B2 (en) 2000-11-08 2008-05-20 Surface Logix, Inc. Biological assays using gradients formed in microfluidic systems
US7033821B2 (en) * 2000-11-08 2006-04-25 Surface Logix, Inc. Device for monitoring cell motility in real-time
US7123764B2 (en) * 2000-11-08 2006-10-17 Surface Logix Inc. Image processing method for use in analyzing data of a chemotaxis or haptotaxis assay
TWI241343B (en) 2000-12-07 2005-10-11 Effector Cell Inst Inc Well unit for detecting cell chemotaxis and separating chemotactic cells
JP3738899B2 (ja) * 2000-12-07 2006-01-25 株式会社 エフェクター細胞研究所 微量試料処理装置
US6923939B1 (en) * 2001-07-05 2005-08-02 Uop Llc Heat activated membrane introduction apparatus and method for screening materials
US20030082632A1 (en) * 2001-10-25 2003-05-01 Cytoprint, Inc. Assay method and apparatus
EP1490520A4 (en) * 2002-03-12 2006-06-07 Surface Logix Inc TEST APPARATUS ANALYZING THE ABSORPTION, METABOLISM, PERMEABILITY AND / OR TOXICITY OF A CANDIDATE COMPOUND
TW200506364A (en) * 2003-04-09 2005-02-16 Effector Cell Inst Inc Apparatus for detecting cell chemo-taxis
US7417726B2 (en) * 2003-09-19 2008-08-26 Applied Biosystems Inc. Normalization of data using controls
US6901945B2 (en) * 2003-09-30 2005-06-07 Nalco Company System for feeding solid materials to a pressurized pipeline
US6972184B2 (en) * 2003-12-23 2005-12-06 Millipore Corporation Cell motility assay
US20050202052A1 (en) * 2004-03-15 2005-09-15 Lee Clemie M. Flavored medicaments to deter or attract and kill microorganisms
US7547525B2 (en) * 2004-08-12 2009-06-16 Neuro Probe Incorporated Point source diffusion cell activity assay
US8673628B2 (en) 2011-06-10 2014-03-18 Essen Instruments, Inc. Methods and apparatus for improving in vitro measurements using boyden chambers
US9644177B2 (en) * 2012-07-12 2017-05-09 Board Of Regents, The University Of Texas System Extracellular matrix films and methods of making and using same
US10384207B2 (en) 2015-07-21 2019-08-20 Neuro Probe Incorporated Assay apparatus and methods
WO2022187684A1 (en) * 2021-03-05 2022-09-09 Enumerix, Inc. Systems and methods for generating droplets and performing digital analyses
CN117241878A (zh) 2021-03-05 2023-12-15 伊努梅里斯公司 用于生成微滴和执行数字分析的系统和方法
US12252745B2 (en) 2021-09-02 2025-03-18 Enumerix, Inc. Detection and digital quantitation of multiple targets

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US3888770A (en) 1971-10-21 1975-06-10 Shlomo Avital Plural-sample filter device
US3929583A (en) 1975-08-14 1975-12-30 Canadian Patents Dev Apparatus for enumerating microorganisms
US4317726A (en) 1981-02-12 1982-03-02 The United States Of America As Represented By The Secretary Of The Army Microbial filter assembly
US4514495A (en) 1982-05-18 1985-04-30 Spiral Systems Instruments, Inc. Method for testing microbial interaction with growth affecting substances
US4493815A (en) 1983-07-28 1985-01-15 Bio-Rad Laboratories, Inc. Supporting and filtering biochemical test plate assembly
US4714674A (en) 1985-02-28 1987-12-22 Genentech, Inc. Chemotactic assay for immunogenicity
US5137023A (en) * 1990-04-19 1992-08-11 Worcester Polytechnic Institute Method and apparatus for monitoring blood analytes noninvasively by pulsatile photoplethysmography
US4912057A (en) 1989-06-13 1990-03-27 Cancer Diagnostics, Inc. Cell chamber for chemotaxis assay
DE69129121T2 (de) * 1990-12-21 1998-11-19 Curative Technologies, Inc., Setauket, N.Y. Angiogene peptide
US5210021A (en) 1991-03-20 1993-05-11 Neuro Probe, Inc. Multiple-site chemotactic test apparatus and method
US5284753A (en) 1991-03-20 1994-02-08 Neuro Probe, Inc. Multiple-site chemotactic test apparatus and method
GB2264169B (en) * 1992-02-07 1995-08-02 Alan John Hayes Fluid monitoring
US5302515A (en) 1992-08-20 1994-04-12 Neuro Probe, Inc. Chemotactic test apparatus and method
US5601997A (en) * 1995-02-03 1997-02-11 Tchao; Ruy Chemotaxis assay procedure
US6329164B1 (en) * 1999-03-18 2001-12-11 Neuro Probe, Incorporated Method for using a cell activity assay apparatus

Also Published As

Publication number Publication date
EP1165745A1 (en) 2002-01-02
EP1165745A4 (en) 2004-10-06
US20020019024A1 (en) 2002-02-14
ATE327315T1 (de) 2006-06-15
WO2000055298A1 (en) 2000-09-21
EP1165745B1 (en) 2006-05-24
JP2002538816A (ja) 2002-11-19
AU3725400A (en) 2000-10-04
DE60028192T2 (de) 2006-11-02
US6329164B1 (en) 2001-12-11
DE60028192D1 (de) 2006-06-29
US6395505B2 (en) 2002-05-28
US6468786B2 (en) 2002-10-22
US20020009796A1 (en) 2002-01-24

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