JP4533134B2 - ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ - Google Patents

ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ Download PDF

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Publication number
JP4533134B2
JP4533134B2 JP2004510752A JP2004510752A JP4533134B2 JP 4533134 B2 JP4533134 B2 JP 4533134B2 JP 2004510752 A JP2004510752 A JP 2004510752A JP 2004510752 A JP2004510752 A JP 2004510752A JP 4533134 B2 JP4533134 B2 JP 4533134B2
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Prior art keywords
policosanol
composition
less
nanoparticulate
active agent
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Expired - Fee Related
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Japanese (ja)
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JP2005531605A5 (cg-RX-API-DMAC7.html
JP2005531605A (ja
Inventor
クーパー，ユージーン，アール．
クライン，ローラ，ジェイ．
リヴァーシッジ，ゲイリー，ジー．
ライド，ニールズ，ピー．
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エラン ファーマ インターナショナル，リミティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004510752A 2002-06-10 2003-06-10 ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ Expired - Fee Related JP4533134B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38746302P 2002-06-10 2002-06-10
PCT/US2003/015409 WO2003103632A1 (en) 2002-06-10 2003-06-10 Nanoparticulate polycosanol formulations and novel polycosanol combinations

Publications (3)

Publication Number Publication Date
JP2005531605A JP2005531605A (ja) 2005-10-20
JP2005531605A5 JP2005531605A5 (cg-RX-API-DMAC7.html) 2006-07-13
JP4533134B2 true JP4533134B2 (ja) 2010-09-01

Family

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JP2004510752A Expired - Fee Related JP4533134B2 (ja) 2002-06-10 2003-06-10 ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ

Country Status (6)

Country Link
US (2) US7763278B2 (cg-RX-API-DMAC7.html)
EP (1) EP1511467A1 (cg-RX-API-DMAC7.html)
JP (1) JP4533134B2 (cg-RX-API-DMAC7.html)
AU (1) AU2003241477A1 (cg-RX-API-DMAC7.html)
CA (1) CA2488498A1 (cg-RX-API-DMAC7.html)
WO (1) WO2003103632A1 (cg-RX-API-DMAC7.html)

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JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を治療する方法
CN114053241B (zh) * 2020-08-06 2023-04-14 湖北中古生物制药有限公司 一种含有多廿烷醇的固体分散体、控释片剂及其制备方法
CN114073681B (zh) * 2020-08-10 2023-04-25 湖北中古生物制药有限公司 一种含有多廿烷醇的胶囊内容物及其制备方法和软胶囊剂
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CN118141097A (zh) * 2024-03-08 2024-06-07 江西省科学院生物资源研究所 一种普利醇纳米制剂及其制备方法

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US7763278B2 (en) 2010-07-27
EP1511467A1 (en) 2005-03-09
US20100143962A1 (en) 2010-06-10
JP2005531605A (ja) 2005-10-20
US20030232796A1 (en) 2003-12-18

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