JP4520993B2 - 動的な光学的画像成形システム - Google Patents
動的な光学的画像成形システム Download PDFInfo
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- JP4520993B2 JP4520993B2 JP2006533282A JP2006533282A JP4520993B2 JP 4520993 B2 JP4520993 B2 JP 4520993B2 JP 2006533282 A JP2006533282 A JP 2006533282A JP 2006533282 A JP2006533282 A JP 2006533282A JP 4520993 B2 JP4520993 B2 JP 4520993B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
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- Liquid Crystal (AREA)
- Control Of Indicators Other Than Cathode Ray Tubes (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
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Description
改良された医療システムは、好ましくは、カテーテルと画像形成システムを含むと共に、短時間で身体組織の広範囲に亘る領域を動的に撮像できるように形成されている。以下に説明する内容は、改良された医療装置を用いた光学的画像形成方法の一実施例である。最初に、実質的に膨張する液体が、長い管状部材により身体管腔内に導入される。次に、光源により広域帯光パルスを発生し、その光パルスを組織用パルスとリファレンスパルスとに分割する。組織用パルスは画像形成体によって身体管腔又は他の身体組織の最初の部位に向けて照射され、身体管腔等から反射した組織用パルスは画像形成体により受光(受信)される。次に、リファレンスパルスの一時的持続時間と組織用パルスの空間形状に対応した光波を生成するために、反射した前記組織用光パルスを、タイムゲートにおいてリファレンスパルスと混合し、そして、複数の検出器によって前記生成された光波を検出する。最後に、身体管腔の第2の部位を撮像するために、内部コアを、好ましくは中心軸芯回りに回転すると共に中心軸芯に沿った長さ方向に移動する。
Claims (16)
- 基端部と先端部を有すると共に、前記先端部が生体内に挿入可能で身体組織を光学的に撮像できるようになっているカテーテルであって、身体組織に液体を導入するための開口を備えた細長い管状部材と、この細長い管状部材の中で摺動できるようになった内部コアとを備えたカテーテルと、
前記内部コアを、前記細長い管状部材内で中心軸芯回りに回転させると共に、中心軸芯に沿って軸芯方向に移動させるようになっている制御システムと、
前記内部コアに光学的に接続されると共に、広域帯光パルスを発生する光源と、
前記光源及び前記内部コアに光学的に接続されると共に、前記光パルスを組織用パルスとリファレンスパルスとに分割し、前記内部コアが前記組織用パルスを身体組織に向けて照射するように構成された可干渉性光学的画像形成システム部と、を備え、
前記可干渉性光学的画像形成システム部は、
身体組織から反射した組織用パルスをリファレンスパルスと混合し、リファレンスパルスの一時的持続時間と反射した組織用パルスの空間形状とに対応した光波を出力するように構成された光混合器と、
前記光波を検出する複数の光検出器を有し、少なくとも毎秒520フレームのフレームレートで前記内部コアから画像を取り込むように構成された画像形成体と、
前記光波から、身体組織の深度構成を前記複数の光検出器に空間的に投影するように構成されたレンズと、を有する動的な光学的画像形成システム。 - 前記可干渉性光学的画像形成システム部は、ガウス型スペクトル密度を作り出すために、前記光波の非ガウス型スペクトル密度をアルゴリズム形成するように構成されている請求項1記載のシステム。
- 前記光源は、複数のスーパールミネンスダイオードを備えている請求項1記載のシステム。
- 前記画像形成体は電荷結合素子を備えている請求項1記載のシステム。
- 前記液体は実質的に膨張する液体である請求項1記載のシステム。
- 前記液体は塩水である請求項1記載のシステム。
- 前記画像形成システム部は、身体組織の三次元画像を形成するようになっている請求項1記載のシステム。
- 前記制御システムは、前記内部コアを回転させると共に軸芯方向に移動させる駆動システムを有しており、
該駆動システムは、
ハウジングと、
該ハウジング内に配置されると共に前記内部コアの基端部に連結された回転継手と、
該回転継手を前記ハウジングに回転可能に支持する高速ボールベアリングと、
該ベアリングの先端部に配置されると共に前記細長い管状部材の内部空間から前記ハウジングを密封する高速シールと、
を備えている請求項1記載のシステム。 - 前記駆動システムは、前記内部コアを、毎秒略6.25mm以上の速度で軸芯方向に移動させるように構成されている請求項8記載のシステム。
- 前記内部コアの先端部に配置されると共に、組織用パルスを身体組織に向けて照射し、該身体組織から反射した組織用パルスを受光する光学的画像形成体を備えた請求項1記載のシステム。
- 前記カテーテルは、基端部に注液口を備えており、該注液口は、細長い管状部材の内部に液体を導入するように構成され、前記導入された液は前記開口を通って身体組織へ導かれるようになっている請求項1記載のシステム。
- 前記注液口は、毎秒略4cm3以下の割合で前記液体を導入するように構成されている請求項11記載のシステム。
- 前記画像形成システム部は、三次元画像を保存するためのメモリを備えている請求項7記載のシステム。
- 前記画像形成システム部は、表示装置を備えると共に、予め決められた比率で複数の三次元画像を表示するように構成されている請求項13記載のシステム。
- 前記画像形成システム部は、1回転で、身体組織の略512分割部位の画像を形成する請求項1記載のシステム。
- 前記内部コアと前記細長い管状部材との間の領域に、潤滑剤を注入している請求項1記載のシステム。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US10/444,171 US7376455B2 (en) | 2003-05-22 | 2003-05-22 | Systems and methods for dynamic optical imaging |
PCT/US2004/015983 WO2004105598A1 (en) | 2003-05-22 | 2004-05-20 | Systems and methods for dynamic optical imaging |
Publications (2)
Publication Number | Publication Date |
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JP2007500059A JP2007500059A (ja) | 2007-01-11 |
JP4520993B2 true JP4520993B2 (ja) | 2010-08-11 |
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JP2006533282A Expired - Fee Related JP4520993B2 (ja) | 2003-05-22 | 2004-05-20 | 動的な光学的画像成形システム |
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Country | Link |
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US (2) | US7376455B2 (ja) |
EP (1) | EP1626655B1 (ja) |
JP (1) | JP4520993B2 (ja) |
AT (1) | ATE422840T1 (ja) |
CA (1) | CA2523703A1 (ja) |
DE (1) | DE602004019516D1 (ja) |
ES (1) | ES2322591T3 (ja) |
WO (1) | WO2004105598A1 (ja) |
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ATE422840T1 (de) | 2009-03-15 |
US7991455B2 (en) | 2011-08-02 |
WO2004105598A1 (en) | 2004-12-09 |
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US20080275304A1 (en) | 2008-11-06 |
ES2322591T3 (es) | 2009-06-23 |
EP1626655A1 (en) | 2006-02-22 |
US7376455B2 (en) | 2008-05-20 |
JP2007500059A (ja) | 2007-01-11 |
US20040236230A1 (en) | 2004-11-25 |
DE602004019516D1 (de) | 2009-04-02 |
CA2523703A1 (en) | 2004-12-09 |
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