JP4454249B2 - 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット - Google Patents
膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット Download PDFInfo
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- JP4454249B2 JP4454249B2 JP2003114380A JP2003114380A JP4454249B2 JP 4454249 B2 JP4454249 B2 JP 4454249B2 JP 2003114380 A JP2003114380 A JP 2003114380A JP 2003114380 A JP2003114380 A JP 2003114380A JP 4454249 B2 JP4454249 B2 JP 4454249B2
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- nucleic acid
- acid probe
- fluorescent dye
- sequence
- probe
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003114380A JP4454249B2 (ja) | 2003-04-18 | 2003-04-18 | 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット |
| EP04728056A EP1616952B1 (en) | 2003-04-18 | 2004-04-16 | Method of detecting pancryatic islet amyloid protein mutant gene and nucleic acid probe and kit therefor |
| AT04728056T ATE428782T1 (de) | 2003-04-18 | 2004-04-16 | Verfahren zum nachweis des gens einer mutante des pankreatischen insel-amyloidproteins sowie nukleinsäuresonde und kit dafür |
| PCT/JP2004/005509 WO2004092382A1 (ja) | 2003-04-18 | 2004-04-16 | 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット |
| CNB200480016499XA CN100404678C (zh) | 2003-04-18 | 2004-04-16 | 检测胰岛淀粉样蛋白突变基因的方法及其核酸探针和试剂盒 |
| DE602004020603T DE602004020603D1 (de) | 2003-04-18 | 2004-04-16 | Verfahren zum nachweis des gens einer mutante des pankreatischen insel-amyloidproteins sowie nukleinsäuresonde und kit dafür |
| US10/553,614 US7332306B2 (en) | 2003-04-18 | 2004-04-16 | Method of detecting pancreatic islet amyloid protein mutant gene and nucleic acid probe and kit therefor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003114380A JP4454249B2 (ja) | 2003-04-18 | 2003-04-18 | 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004313119A JP2004313119A (ja) | 2004-11-11 |
| JP2004313119A5 JP2004313119A5 (https=) | 2006-04-27 |
| JP4454249B2 true JP4454249B2 (ja) | 2010-04-21 |
Family
ID=33296147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003114380A Expired - Fee Related JP4454249B2 (ja) | 2003-04-18 | 2003-04-18 | 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7332306B2 (https=) |
| EP (1) | EP1616952B1 (https=) |
| JP (1) | JP4454249B2 (https=) |
| CN (1) | CN100404678C (https=) |
| AT (1) | ATE428782T1 (https=) |
| DE (1) | DE602004020603D1 (https=) |
| WO (1) | WO2004092382A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2009011297A1 (ja) * | 2007-07-13 | 2010-09-24 | アークレイ株式会社 | Ｊａｋ２遺伝子の変異検出用プローブおよびその用途 |
| EP2447378B1 (en) * | 2010-10-29 | 2017-06-21 | ARKRAY, Inc. | Probe for detection of polymorphism in EGFR gene, amplification primer, and use thereof |
| CN105717182B (zh) * | 2016-03-10 | 2018-05-11 | 中南大学 | 一种用于同步检测淀粉样多肽单体和聚集体的生物传感器及其构建方法和应用 |
| CN108489941B (zh) * | 2018-01-31 | 2021-07-27 | 吉林大学 | 溴酚蓝在作为检测牛胰岛素淀粉样纤维探针和作为牛胰岛素淀粉样纤维抑制剂方面的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2383939C (en) | 2000-06-27 | 2009-12-01 | National Institute Of Advanced Industrial Science And Technology | Novel nucleic acid probes, method for determining nucleic acids by using the probes, and method for analyzing data obtained by the method |
| JP3963422B2 (ja) * | 2000-08-03 | 2007-08-22 | 日鉄環境エンジニアリング株式会社 | 核酸の測定方法 |
| ATE332398T1 (de) * | 2000-08-11 | 2006-07-15 | Univ Utah Res Found | Einfach markierte oligonukleotidsonden |
| CN1496412B (zh) * | 2001-03-14 | 2012-08-08 | 香港中文大学 | 用于评估中国血统的人种发展2型糖尿病危险性的方法和组合物 |
| JPWO2003100095A1 (ja) | 2002-05-08 | 2005-09-22 | アークレイ株式会社 | 標的核酸の検出法 |
-
2003
- 2003-04-18 JP JP2003114380A patent/JP4454249B2/ja not_active Expired - Fee Related
-
2004
- 2004-04-16 AT AT04728056T patent/ATE428782T1/de not_active IP Right Cessation
- 2004-04-16 US US10/553,614 patent/US7332306B2/en not_active Expired - Fee Related
- 2004-04-16 WO PCT/JP2004/005509 patent/WO2004092382A1/ja not_active Ceased
- 2004-04-16 DE DE602004020603T patent/DE602004020603D1/de not_active Expired - Lifetime
- 2004-04-16 EP EP04728056A patent/EP1616952B1/en not_active Expired - Lifetime
- 2004-04-16 CN CNB200480016499XA patent/CN100404678C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004020603D1 (de) | 2009-05-28 |
| WO2004092382A1 (ja) | 2004-10-28 |
| EP1616952B1 (en) | 2009-04-15 |
| US7332306B2 (en) | 2008-02-19 |
| ATE428782T1 (de) | 2009-05-15 |
| CN100404678C (zh) | 2008-07-23 |
| EP1616952A1 (en) | 2006-01-18 |
| EP1616952A4 (en) | 2006-08-09 |
| US20060275772A1 (en) | 2006-12-07 |
| CN1806046A (zh) | 2006-07-19 |
| JP2004313119A (ja) | 2004-11-11 |
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