CN100404678C - 检测胰岛淀粉样蛋白突变基因的方法及其核酸探针和试剂盒 - Google Patents

检测胰岛淀粉样蛋白突变基因的方法及其核酸探针和试剂盒 Download PDF

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CN100404678C
CN100404678C CNB200480016499XA CN200480016499A CN100404678C CN 100404678 C CN100404678 C CN 100404678C CN B200480016499X A CNB200480016499X A CN B200480016499XA CN 200480016499 A CN200480016499 A CN 200480016499A CN 100404678 C CN100404678 C CN 100404678C
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nucleic acid
probe
nucleotide sequence
acid probe
nucleotide
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CN1806046A (zh
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平井光春
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Arkray Inc
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Arkray Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNB200480016499XA 2003-04-18 2004-04-16 检测胰岛淀粉样蛋白突变基因的方法及其核酸探针和试剂盒 Expired - Fee Related CN100404678C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003114380A JP4454249B2 (ja) 2003-04-18 2003-04-18 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット
JP114380/2003 2003-04-18

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CN1806046A CN1806046A (zh) 2006-07-19
CN100404678C true CN100404678C (zh) 2008-07-23

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US (1) US7332306B2 (https=)
EP (1) EP1616952B1 (https=)
JP (1) JP4454249B2 (https=)
CN (1) CN100404678C (https=)
AT (1) ATE428782T1 (https=)
DE (1) DE602004020603D1 (https=)
WO (1) WO2004092382A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2009011297A1 (ja) * 2007-07-13 2010-09-24 アークレイ株式会社 Ｊａｋ２遺伝子の変異検出用プローブおよびその用途
EP2447378B1 (en) * 2010-10-29 2017-06-21 ARKRAY, Inc. Probe for detection of polymorphism in EGFR gene, amplification primer, and use thereof
CN105717182B (zh) * 2016-03-10 2018-05-11 中南大学 一种用于同步检测淀粉样多肽单体和聚集体的生物传感器及其构建方法和应用
CN108489941B (zh) * 2018-01-31 2021-07-27 吉林大学 溴酚蓝在作为检测牛胰岛素淀粉样纤维探针和作为牛胰岛素淀粉样纤维抑制剂方面的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002014555A2 (en) * 2000-08-11 2002-02-21 University Of Utah Research Foundation Single-labeled oligonucleotide probes
JP2002119291A (ja) * 2000-08-03 2002-04-23 Japan Bioindustry Association 核酸の測定方法、それに用いる核酸プローブ及びその方法によって得られるデータを解析する方法
WO2002072875A1 (en) * 2001-03-14 2002-09-19 The Chinese University Of Hong Kong Method and compositions for evaluating risk of developing type 2 diabetes in people of chinese descent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383939C (en) 2000-06-27 2009-12-01 National Institute Of Advanced Industrial Science And Technology Novel nucleic acid probes, method for determining nucleic acids by using the probes, and method for analyzing data obtained by the method
JPWO2003100095A1 (ja) 2002-05-08 2005-09-22 アークレイ株式会社 標的核酸の検出法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002119291A (ja) * 2000-08-03 2002-04-23 Japan Bioindustry Association 核酸の測定方法、それに用いる核酸プローブ及びその方法によって得られるデータを解析する方法
WO2002014555A2 (en) * 2000-08-11 2002-02-21 University Of Utah Research Foundation Single-labeled oligonucleotide probes
WO2002072875A1 (en) * 2001-03-14 2002-09-19 The Chinese University Of Hong Kong Method and compositions for evaluating risk of developing type 2 diabetes in people of chinese descent

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DYNAMIC ALLELE-SPECIFIC HYBRIDIZATION: A NEWMETHOD FOR SCORING SINGLE NUCLEOTIDEPOLYMORPHISMS. HOWELL WM等.NATURE BIOTECHNOLOGY,Vol.17 No.1. 1999 *
EFFECT OF PRIMARY AND SECONDARY STRUCTUREOF OLIGODEOXYRIBONUCLEOTIDES ON THEFLUORESCENT PROPERTIES OF CONJUGATED DYES. NAZARENKO等.NUCLEIC ACIDS RESEARCH,Vol.30 No.9. 2002 *
RAPID DETECTION OF POINT MUTATIONS BYFLUORESCENCE RESONANCE ENERGY TRANSFER ANDPROBE MELTING CURVES IN CANDIDA SPECIES. J. LOEFFLER等.CLIN. CHEM.,Vol.46 No.5. 2000 *

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Publication number Publication date
DE602004020603D1 (de) 2009-05-28
WO2004092382A1 (ja) 2004-10-28
EP1616952B1 (en) 2009-04-15
US7332306B2 (en) 2008-02-19
ATE428782T1 (de) 2009-05-15
EP1616952A1 (en) 2006-01-18
EP1616952A4 (en) 2006-08-09
US20060275772A1 (en) 2006-12-07
CN1806046A (zh) 2006-07-19
JP4454249B2 (ja) 2010-04-21
JP2004313119A (ja) 2004-11-11

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