JP4423450B2 - 新規の干渉計を用いた光学コヒーレンス断層撮影 - Google Patents

新規の干渉計を用いた光学コヒーレンス断層撮影 Download PDF

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JP4423450B2
JP4423450B2 JP13367099A JP13367099A JP4423450B2 JP 4423450 B2 JP4423450 B2 JP 4423450B2 JP 13367099 A JP13367099 A JP 13367099A JP 13367099 A JP13367099 A JP 13367099A JP 4423450 B2 JP4423450 B2 JP 4423450B2
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radiation
coherence tomography
optical coherence
coupled
coupler
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JP2000002516A5 (enExample
JP2000002516A (ja
Inventor
デビッド・ファング
クリストファー・エル・ピーターセン
ジェイ・ウェイ
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カール・ツアイス・メディテック・アーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1005—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
    • G01B9/02002—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02015—Interferometers characterised by the beam path configuration
    • G01B9/02027—Two or more interferometric channels or interferometers
    • G01B9/02028—Two or more reference or object arms in one interferometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/0209—Low-coherence interferometers
    • G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
    • G01B2290/15—Cat eye, i.e. reflection always parallel to incoming beam
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
    • G01B2290/35—Mechanical variable delay line

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pathology (AREA)
  • Instruments For Measurement Of Length By Optical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Eye Examination Apparatus (AREA)
JP13367099A 1998-05-15 1999-05-14 新規の干渉計を用いた光学コヒーレンス断層撮影 Expired - Fee Related JP4423450B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/079,908 US6053613A (en) 1998-05-15 1998-05-15 Optical coherence tomography with new interferometer
US09/079908 1998-05-15

Publications (3)

Publication Number Publication Date
JP2000002516A JP2000002516A (ja) 2000-01-07
JP2000002516A5 JP2000002516A5 (enExample) 2006-06-29
JP4423450B2 true JP4423450B2 (ja) 2010-03-03

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JP13367099A Expired - Fee Related JP4423450B2 (ja) 1998-05-15 1999-05-14 新規の干渉計を用いた光学コヒーレンス断層撮影

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US (1) US6053613A (enExample)
EP (1) EP0956809B1 (enExample)
JP (1) JP4423450B2 (enExample)
DE (1) DE69940087D1 (enExample)

Families Citing this family (207)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6615072B1 (en) * 1999-02-04 2003-09-02 Olympus Optical Co., Ltd. Optical imaging device
DE10020559A1 (de) * 2000-04-27 2001-10-31 Hannover Laser Zentrum Laser-Bearbeitung von Materialien
DE10042751A1 (de) * 2000-08-31 2002-03-14 Thomas Hellmuth System zur berührungslosen Vermessung der optischen Abbildungsqualität eines Auges
WO2002021074A2 (en) 2000-09-04 2002-03-14 Forskningscenter Risø Optical amplification in coherence reflectometry
ATE454845T1 (de) * 2000-10-30 2010-01-15 Gen Hospital Corp Optische systeme zur gewebeanalyse
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
US7048690B2 (en) * 2001-03-20 2006-05-23 Cornell Research Foundation, Inc. Precision ultrasound measurement for intraocular lens placement
WO2002088684A1 (en) * 2001-04-30 2002-11-07 The General Hospital Corporation Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating
WO2002088705A2 (en) 2001-05-01 2002-11-07 The General Hospital Corporation Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties
DE10151216A1 (de) * 2001-10-16 2003-04-24 Zeiss Carl Jena Gmbh Verfahren zur optischen Erfassung von charakteristischen Größen einer beleuchteten Probe
US6980299B1 (en) 2001-10-16 2005-12-27 General Hospital Corporation Systems and methods for imaging a sample
AU2003207507A1 (en) * 2002-01-11 2003-07-30 Gen Hospital Corp Apparatus for oct imaging with axial line focus for improved resolution and depth of field
EP1471821B1 (en) * 2002-01-15 2013-06-26 Board Of Regents, The University Of Texas System Compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures
US7355716B2 (en) 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US20110201924A1 (en) * 2002-04-30 2011-08-18 The General Hospital Corporation Method and Apparatus for Improving Image Clarity and Sensitivity in Optical Tomography Using Dynamic Feedback to Control Focal Properties and Coherence Gating
US7643153B2 (en) * 2003-01-24 2010-01-05 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US7761139B2 (en) * 2003-01-24 2010-07-20 The General Hospital Corporation System and method for identifying tissue using low-coherence interferometry
WO2004073501A2 (en) * 2003-02-20 2004-09-02 Gutin Mikhail Optical coherence tomography with 3d coherence scanning
US6988801B2 (en) * 2003-03-25 2006-01-24 University Of Rochester Compact portable wavefront sensor
CA2519937C (en) 2003-03-31 2012-11-20 Guillermo J. Tearney Speckle reduction in optical coherence tomography by path length encoded angular compounding
RU2247938C1 (ru) * 2003-05-27 2005-03-10 Геликонов Валентин Михайлович Оптическое устройство для исследования объекта
TWI223719B (en) * 2003-05-30 2004-11-11 Ind Tech Res Inst Sub-micrometer-resolution optical coherent tomography
ES2310744T3 (es) * 2003-06-06 2009-01-16 The General Hospital Corporation Fuente de luz sintonizable en longitudes de onda.
US7876974B2 (en) * 2003-08-29 2011-01-25 Vladimir Brajovic Method for improving digital images and an image sensor for sensing the same
EP2278287B1 (en) 2003-10-27 2016-09-07 The General Hospital Corporation Method and apparatus for performing optical imaging using frequency-domain interferometry
EP1687587B1 (en) * 2003-11-28 2020-01-08 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
WO2005077256A1 (en) * 2004-02-06 2005-08-25 Optovue, Inc. Optical apparatus and methods for performing eye examinations
AT501056B1 (de) * 2004-02-06 2007-04-15 Zeiss Carl Meditec Ag Kurzkohärenz-interferometrische längenmessung am auge
JP2007522456A (ja) * 2004-02-10 2007-08-09 オプトビュー，インコーポレーテッド 高効率低コヒーレンス干渉法
US20050254059A1 (en) * 2004-05-14 2005-11-17 Alphonse Gerard A Low coherence interferometric system for optical metrology
US7327463B2 (en) 2004-05-14 2008-02-05 Medrikon Corporation Low coherence interferometry utilizing magnitude
US7190464B2 (en) * 2004-05-14 2007-03-13 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
US7184148B2 (en) 2004-05-14 2007-02-27 Medeikon Corporation Low coherence interferometry utilizing phase
US7474408B2 (en) * 2004-05-14 2009-01-06 Medeikon Corporation Low coherence interferometry utilizing phase
US7242480B2 (en) * 2004-05-14 2007-07-10 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
US8018598B2 (en) 2004-05-29 2011-09-13 The General Hospital Corporation Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (OCT) imaging
AU2005270037B2 (en) 2004-07-02 2012-02-09 The General Hospital Corporation Endoscopic imaging probe comprising dual clad fibre
JP5053845B2 (ja) * 2004-08-06 2012-10-24 ザ ジェネラル ホスピタル コーポレイション 光学コヒーレンス断層撮影法を使用して試料中の少なくとも１つの位置を決定するための方法、システムおよびソフトウェア装置
EP1989997A1 (en) 2004-08-24 2008-11-12 The General Hospital Corporation Process, System and Software Arrangement for Measuring a Mechanical Strain and Elastic Properties of a Sample
JP5324095B2 (ja) 2004-08-24 2013-10-23 ザ ジェネラル ホスピタル コーポレイション 血管セグメントを画像化する方法および装置
US7365859B2 (en) * 2004-09-10 2008-04-29 The General Hospital Corporation System and method for optical coherence imaging
EP1804638B1 (en) * 2004-09-29 2012-12-19 The General Hospital Corporation System and method for optical coherence imaging
EP1819270B1 (en) * 2004-10-29 2012-12-19 The General Hospital Corporation Polarization-sensitive optical coherence tomography
EP1807722B1 (en) * 2004-11-02 2022-08-10 The General Hospital Corporation Fiber-optic rotational device, optical system for imaging a sample
EP2278266A3 (en) * 2004-11-24 2011-06-29 The General Hospital Corporation Common-Path Interferometer for Endoscopic OCT
WO2006058346A1 (en) 2004-11-29 2006-06-01 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
US7809171B2 (en) * 2005-01-10 2010-10-05 Battelle Memorial Institute Facial feature evaluation based on eye location
US8394084B2 (en) 2005-01-10 2013-03-12 Optimedica Corporation Apparatus for patterned plasma-mediated laser trephination of the lens capsule and three dimensional phaco-segmentation
WO2006078802A1 (en) * 2005-01-21 2006-07-27 Massachusetts Institute Of Technology Methods and apparatus for optical coherence tomography scanning
EP2325803A1 (en) 2005-04-28 2011-05-25 The General Hospital Corporation Evaluating optical coherence tomography information for an anatomical structure
EP1887926B1 (en) * 2005-05-31 2014-07-30 The General Hospital Corporation System and method which use spectral encoding heterodyne interferometry techniques for imaging
EP1889037A2 (en) 2005-06-01 2008-02-20 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
WO2007008788A2 (en) * 2005-07-08 2007-01-18 Imalux Corporation Common-path frequency-domain optical coherence reflectometer and optical coherence tomography device
DE602006017558D1 (de) 2005-08-09 2010-11-25 Gen Hospital Corp Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie
EP1940286A1 (en) 2005-09-29 2008-07-09 General Hospital Corporation Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions
US7400410B2 (en) 2005-10-05 2008-07-15 Carl Zeiss Meditec, Inc. Optical coherence tomography for eye-length measurement
JP5203951B2 (ja) * 2005-10-14 2013-06-05 ザ ジェネラル ホスピタル コーポレイション スペクトル及び周波数符号化蛍光画像形成
DE102005059923A1 (de) * 2005-12-13 2007-06-14 Oculus Optikgeräte GmbH Verfahren und Vorrichtung zur Bestimmung des Abstandes zu einem Messpunkt auf einer Gewebefläche des Auges
DE102005062238A1 (de) * 2005-12-22 2007-07-05 Carl Zeiss Meditec Ag Ophthalmologisches Messsystem und Verfahren zur Ermittlung der biometrischen Daten eines Auges
US7796270B2 (en) 2006-01-10 2010-09-14 The General Hospital Corporation Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques
WO2007084945A1 (en) * 2006-01-19 2007-07-26 The General Hospital Corporation Systems and methods for performing rapid fluorescense lifetime, excitation and emission spectral measurements
CN101384212A (zh) 2006-01-19 2009-03-11 通用医疗公司 通过上皮内腔器官束扫描对上皮内腔器官进行光学成像的方法和系统
WO2007084903A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements
US20070171430A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and methods for providing mirror tunnel micropscopy
US10426548B2 (en) * 2006-02-01 2019-10-01 The General Hosppital Corporation Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
US9186066B2 (en) 2006-02-01 2015-11-17 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
WO2007149601A2 (en) 2006-02-01 2007-12-27 The General Hospital Corporation Apparatus for controlling at least one of at least two sections of at least one fiber
EP3143926B1 (en) 2006-02-08 2020-07-01 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
JP2009527770A (ja) 2006-02-24 2009-07-30 ザ ジェネラル ホスピタル コーポレイション 角度分解型のフーリエドメイン光干渉断層撮影法を遂行する方法及びシステム
US20070208400A1 (en) * 2006-03-01 2007-09-06 The General Hospital Corporation System and method for providing cell specific laser therapy of atherosclerotic plaques by targeting light absorbers in macrophages
WO2007109540A2 (en) * 2006-03-17 2007-09-27 The General Hospital Corporation Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry
US7742173B2 (en) * 2006-04-05 2010-06-22 The General Hospital Corporation Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
EP3150110B1 (en) 2006-05-10 2020-09-02 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
US7782464B2 (en) * 2006-05-12 2010-08-24 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
JP4907227B2 (ja) * 2006-05-29 2012-03-28 株式会社ニデック 眼内寸法測定装置
US7488930B2 (en) * 2006-06-02 2009-02-10 Medeikon Corporation Multi-channel low coherence interferometer
EP2054712B1 (en) 2006-08-25 2015-10-07 The General Hospital Corporation Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques
US7452077B2 (en) * 2006-08-29 2008-11-18 Carl Zeiss Meditec, Inc. Image adjustment derived from optical imaging measurement data
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
WO2008089406A2 (en) 2007-01-19 2008-07-24 The General Hospital Corporation Apparatus and method for simultaneous inspection at different depths based on the principle of frequency domain optical coherence tomography
WO2008089342A1 (en) 2007-01-19 2008-07-24 The General Hospital Corporation Rotating disk reflection for fast wavelength scanning of dispersed broadband light
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
DE502007004384D1 (de) 2007-02-21 2010-08-26 Agfa Healthcare Nv System und Verfahren zur optischen Kohärenztomographie
EP1962049B1 (de) * 2007-02-21 2015-12-23 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP2267403A3 (de) * 2007-02-21 2011-04-20 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP1962081B1 (de) 2007-02-21 2016-09-14 Agfa HealthCare N.V. System zur optischen Kohärenztomographie
EP1962079B1 (de) 2007-02-21 2016-06-01 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP1962080B1 (de) 2007-02-21 2011-06-01 Agfa HealthCare N.V. System zur optischen Kohärenztomographie
EP1962051A1 (de) * 2007-02-21 2008-08-27 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP2339329A3 (de) 2007-02-21 2012-04-04 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
CN103169568B (zh) 2007-03-13 2015-07-15 眼科医疗公司 用于创建切口以提高人工晶状体设置的装置
WO2008116010A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome exemplary laser speckle imaging procedure
EP2602651A3 (en) 2007-03-23 2014-08-27 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
DE102007016444B4 (de) * 2007-04-05 2024-08-22 Precitec Optronik Gmbh Bearbeitungseinrichtung
US8045177B2 (en) 2007-04-17 2011-10-25 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy
US8115919B2 (en) 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
WO2009018456A2 (en) * 2007-07-31 2009-02-05 The General Hospital Corporation Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging
EP2191254B1 (en) 2007-08-31 2017-07-19 The General Hospital Corporation System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith
US8076624B1 (en) 2007-09-19 2011-12-13 Barchers Jeffrey D Non-cooperative laser target enhancement system and method
US8787774B2 (en) * 2007-10-10 2014-07-22 Luxtera, Inc. Method and system for a narrowband, non-linear optoelectronic receiver
WO2009059034A1 (en) * 2007-10-30 2009-05-07 The General Hospital Corporation System and method for cladding mode detection
US7800759B2 (en) * 2007-12-11 2010-09-21 Bausch & Lomb Incorporated Eye length measurement apparatus
WO2009085690A1 (en) * 2007-12-21 2009-07-09 Bausch & Lomb Incorporated Ophthalmic instrument alignment apparatus and method of using same
WO2009088947A2 (en) 2008-01-02 2009-07-16 Arcscan, Inc. Components for an ultrasonic arc scanning apparatus
US10531859B2 (en) 2008-01-02 2020-01-14 Arcscan, Inc. Components for a precision ultrasonic scanning apparatus for body parts
US20090225324A1 (en) * 2008-01-17 2009-09-10 The General Hospital Corporation Apparatus for providing endoscopic high-speed optical coherence tomography
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
US9332942B2 (en) * 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
US10426348B2 (en) 2008-03-05 2019-10-01 Purdue Research Foundation Using differential time-frequency tissue-response spectroscopy to evaluate living body response to a drug
US10080684B2 (en) 2008-03-13 2018-09-25 Optimedica Corporation System and method for laser corneal incisions for keratoplasty procedures
US10646116B2 (en) 2013-07-25 2020-05-12 Amo Development, Llc In situ determination of refractive index of materials
US8496588B2 (en) 2008-04-03 2013-07-30 Arcscan, Inc. Procedures for an ultrasonic arc scanning apparatus
US8421855B2 (en) * 2008-04-23 2013-04-16 Bioptigen, Inc. Optical coherence tomography (OCT) imaging systems for use in pediatric ophthalmic applications and related methods and computer program products
US8593619B2 (en) 2008-05-07 2013-11-26 The General Hospital Corporation System, method and computer-accessible medium for tracking vessel motion during three-dimensional coronary artery microscopy
WO2009146434A1 (en) * 2008-05-29 2009-12-03 Arcscan, Inc. Compound scanning head for an ultrasonic scanning apparatus
JP5795531B2 (ja) 2008-06-20 2015-10-14 ザ ジェネラル ホスピタル コーポレイション フューズドファイバオプティックカプラ構造、及びその使用方法
WO2010009136A2 (en) * 2008-07-14 2010-01-21 The General Hospital Corporation Apparatus and methods for color endoscopy
EP2359121A4 (en) 2008-12-10 2013-08-14 Gen Hospital Corp SYSTEMS, DEVICE AND METHOD FOR EXPANDING THE IMAGING DEPTH RANGE IN OPTICAL COHERENCE TOMOPOMAGRAPH BY OPTICAL SUB-TESTING
EP2375991A1 (en) 2008-12-15 2011-10-19 ArcScan, Inc. Alignment and imaging of an eye with an ultrasonic scanner
US9149254B2 (en) 2008-12-15 2015-10-06 Arcscan, Inc. Alignment and imaging of an eye with an ultrasonic scanner
US8294971B2 (en) * 2008-12-18 2012-10-23 Bausch • Lomb Incorporated Apparatus comprising an optical path delay scanner
JP2012515930A (ja) 2009-01-26 2012-07-12 ザ ジェネラル ホスピタル コーポレーション 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体
US9178330B2 (en) 2009-02-04 2015-11-03 The General Hospital Corporation Apparatus and method for utilization of a high-speed optical wavelength tuning source
JP5249073B2 (ja) * 2009-02-12 2013-07-31 株式会社ニデック 光干渉式距離計測装置
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
JP5258052B2 (ja) * 2009-04-25 2013-08-07 国立大学法人宇都宮大学 位相シフト法による形状測定方法及び形状測定装置、並びに複素振幅計測方法及び複素振幅計測装置
JP5545618B2 (ja) * 2009-07-06 2014-07-09 株式会社ニデック 眼寸法測定装置
BR112012001042A2 (pt) 2009-07-14 2016-11-22 Gen Hospital Corp equipamento e método de medição do fluxo de fluído dentro de estrutura anatômica.
US8510883B2 (en) * 2009-10-30 2013-08-20 Arcscan, Inc. Method of positioning a patient for medical procedures
US20110184395A1 (en) * 2009-12-23 2011-07-28 Optimedica Corporation Method for laser capsulotomy and lens conditioning
JP5763681B2 (ja) * 2010-01-22 2015-08-12 オプティメディカ・コーポレイション 走査レーザによる嚢切開を自動配置する装置
US9278028B2 (en) * 2010-02-08 2016-03-08 Optimedica Corporation System and method for plasma-mediated modification of tissue
EP2542145B1 (en) 2010-03-05 2020-08-12 The General Hospital Corporation Systems which provide microscopic images of at least one anatomical structure at a particular resolution
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
EP2575597B1 (en) 2010-05-25 2022-05-04 The General Hospital Corporation Apparatus for providing optical imaging of structures and compositions
US9795301B2 (en) 2010-05-25 2017-10-24 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
WO2011153434A2 (en) 2010-06-03 2011-12-08 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
US9514271B2 (en) * 2010-06-17 2016-12-06 Purdue Research Foundation Digital holographic method of measuring cellular activity and measuring apparatus with improved stability
US10401793B2 (en) 2010-06-17 2019-09-03 Purdue Research Foundation Digital holographic method of measuring cellular activity and measuring apparatus with improved stability
JP5883018B2 (ja) 2010-10-27 2016-03-09 ザ ジェネラル ホスピタル コーポレイション 少なくとも１つの血管内部の血圧を測定するための装置、システム、および方法
US8437007B2 (en) 2010-12-30 2013-05-07 Axsun Technologies, Inc. Integrated optical coherence tomography system
US9046337B2 (en) 2010-12-30 2015-06-02 Volcano Corporation Integrated OCT detector system with transimpedance amplifier
US20130321822A1 (en) * 2011-02-15 2013-12-05 Klaus Vogler System and method for measuring internal dimensions of an object by optical coherence tomography
US8721077B2 (en) 2011-04-29 2014-05-13 The General Hospital Corporation Systems, methods and computer-readable medium for determining depth-resolved physical and/or optical properties of scattering media by analyzing measured data over a range of depths
WO2013013049A1 (en) 2011-07-19 2013-01-24 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
EP2748587B1 (en) 2011-08-25 2021-01-13 The General Hospital Corporation Methods and arrangements for providing micro-optical coherence tomography procedures
US9341783B2 (en) 2011-10-18 2016-05-17 The General Hospital Corporation Apparatus and methods for producing and/or providing recirculating optical delay(s)
ITPI20120009A1 (it) * 2012-01-24 2013-07-25 Visia Imaging S R L "un metodo per ridurre il tempo della misura a scansione della lunghezza assiale oculare e dispositivo per attuare tale metodo"
US9629528B2 (en) 2012-03-30 2017-04-25 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
US9597059B2 (en) 2012-05-17 2017-03-21 Arcscan, Inc. Correcting for unintended motion for ultrasonic eye scans
EP2852315A4 (en) 2012-05-21 2016-06-08 Gen Hospital Corp DEVICE, APPARATUS AND METHOD FOR CAPSULE MICROSCOPY
US9320427B2 (en) 2012-07-09 2016-04-26 Arcscan, Inc. Combination optical and ultrasonic imaging of an eye
JP6227652B2 (ja) 2012-08-22 2017-11-08 ザ ジェネラル ホスピタル コーポレイション ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体
US10702209B2 (en) 2012-10-24 2020-07-07 Amo Development, Llc Graphical user interface for laser eye surgery system
US10292863B2 (en) 2012-11-02 2019-05-21 Optimedica Corporation Interface force feedback in a laser eye surgery system
US10314746B2 (en) 2012-11-02 2019-06-11 Optimedica Corporation Laser eye surgery system calibration
US10278862B2 (en) 2012-11-02 2019-05-07 Optimedica Corporation Low voltage communication between subsystems in a laser eye surgery system
US10285860B2 (en) 2012-11-02 2019-05-14 Optimedica Corporation Vacuum loss detection during laser eye surgery
US9445946B2 (en) 2012-11-02 2016-09-20 Optimedica Corporation Laser eye surgery system
AU2013337653B2 (en) 2012-11-02 2017-11-30 Optimedica Corporation Optical surface identification for laser surgery
US9987165B2 (en) 2012-11-02 2018-06-05 Optimedica Corporation Liquid optical interface for laser eye surgery system
US10624786B2 (en) 2012-11-02 2020-04-21 Amo Development, Llc Monitoring laser pulse energy in a laser eye surgery system
EP2929327B1 (en) 2012-12-05 2019-08-14 Perimeter Medical Imaging, Inc. System and method for wide field oct imaging
US10893806B2 (en) 2013-01-29 2021-01-19 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
US10022270B2 (en) 2013-03-14 2018-07-17 Optimedica Corporation Laser capsulovitreotomy
CA3144057A1 (en) 2013-03-15 2014-09-25 Optimedica Corporation Microfemtotomy methods and systems
WO2014144709A2 (en) 2013-03-15 2014-09-18 The General Hospital Corporation Methods and systems for characterizing an object
US10369053B2 (en) 2013-04-17 2019-08-06 Optimedica Corporation Corneal topography measurements and fiducial mark incisions in laser surgical procedures
EP2986258B1 (en) 2013-04-17 2018-11-28 Optimedica Corporation Laser fiducials for axis alignment in cataract surgery
CN109009658B (zh) 2013-04-18 2021-03-05 光学医疗公司 角膜手术程序的角膜形貌测量和对准
EP2997354A4 (en) 2013-05-13 2017-01-18 The General Hospital Corporation Detecting self-interefering fluorescence phase and amplitude
EP3021735A4 (en) 2013-07-19 2017-04-19 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
WO2015009932A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Imaging apparatus and method which utilizes multidirectional field of view endoscopy
WO2015013651A2 (en) 2013-07-26 2015-01-29 The General Hospital Corporation System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography
US9918873B2 (en) 2013-10-08 2018-03-20 Optimedica Corporation Laser eye surgery system calibration
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
AU2015214447B2 (en) 2014-02-04 2020-03-05 Amo Development, Llc System and method for laser corneal incisions for keratoplasty procedures
US10736605B2 (en) 2014-02-24 2020-08-11 Arcscan, Inc. Disposable eyepiece system for an ultrasonic eye scanning apparatus
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
JP2017525435A (ja) 2014-07-25 2017-09-07 ザ ジェネラル ホスピタル コーポレイション インビボ・イメージングおよび診断のための機器、デバイスならびに方法
AU2015320309B2 (en) * 2014-09-25 2020-07-23 Amo Development, Llc Methods and systems for corneal topography, blink detection and laser eye surgery
CA2964800A1 (en) 2014-10-17 2016-04-21 Optimedica Corporation Vacuum loss detection during laser eye surgery
WO2016061547A1 (en) 2014-10-17 2016-04-21 Optimedica Corporation Automatic patient positioning within a laser eye surgery system
EP3270840B1 (en) 2015-03-18 2019-06-05 Optimedica Corporation Vacuum loss detection during laser eye surgery
CA2991479A1 (en) 2015-07-08 2017-01-12 Optimedica Corporation Image processing method and system for edge detection and laser eye surgery system incorporating the same
US11426611B2 (en) 2015-10-13 2022-08-30 Arcscan, Inc. Ultrasound therapeutic and scanning apparatus
WO2017066460A1 (en) 2015-10-13 2017-04-20 Arcscan, Inc Ultrasonic scanning apparatus
WO2017196306A1 (en) 2016-05-10 2017-11-16 Optimedica Corporation Laser eye surgery systems and methods of treating vitreous and ocular floaters
DE102016110005A1 (de) * 2016-05-31 2017-11-30 Universität Zu Lübeck Vorrichtung zur Brechkraftänderung der Cornea
EP3628282B1 (en) 2016-09-14 2022-10-19 AMO Development, LLC Free floating patient interface for laser surgery system
CA3037296A1 (en) 2016-09-19 2018-03-22 Optimedica Corporation Systems for opthalmic measurements and laser surgery and systems for surgical planning based thereon
AU2017382218B2 (en) 2016-12-21 2023-05-11 Acucela Inc. Miniaturized mobile, low cost optical coherence tomography system for home based ophthalmic applications
WO2019014767A1 (en) 2017-07-18 2019-01-24 Perimeter Medical Imaging, Inc. SAMPLE CONTAINER FOR STABILIZING AND ALIGNING EXCISED ORGANIC TISSUE SAMPLES FOR EX VIVO ANALYSIS
CA3103899A1 (en) 2018-06-20 2019-12-26 Acucela Inc. Miniaturized mobile, low cost optical coherence tomography system for home based ophthalmic applications
US20200038241A1 (en) 2018-08-02 2020-02-06 Optimedica Corporation Full depth laser ophthalmic surgical system, methods of calibrating the surgical system and treatment methods using the same
US11000413B2 (en) 2019-02-15 2021-05-11 Amo Development, Llc Ophthalmic laser surgical system and method implementing simultaneous laser treatment and OCT measurement
EP4081096A4 (en) 2019-12-26 2024-01-10 Acucela Inc. OPTICAL COHERENCE TOMOGRAPHY PATIENT ALIGNMENT SYSTEM FOR HOME OPHTHALMIC APPLICATIONS
US10959613B1 (en) 2020-08-04 2021-03-30 Acucela Inc. Scan pattern and signal processing for optical coherence tomography
EP4195998A4 (en) 2020-08-14 2024-08-21 Acucela Inc. SYSTEM AND METHOD FOR DECREASING CURVATURE ALIGNMENT OF OPTICAL COHERENCE TOMOGRAPHY A-SCAN
US11393094B2 (en) 2020-09-11 2022-07-19 Acucela Inc. Artificial intelligence for evaluation of optical coherence tomography images
CN116322471A (zh) 2020-09-30 2023-06-23 奥克塞拉有限公司 近视预测、诊断、计划和监测设备
WO2022204622A1 (en) 2021-03-24 2022-09-29 Acucela Inc. Axial length measurement monitor
DE102021131831A1 (de) 2021-12-02 2022-11-17 Lessmüller Lasertechnik GmbH Messvorrichtung für ein Bearbeitungssystem, Bearbeitungssystem und Verfahren zum Einstellen einer Messvorrichtung für ein Bearbeitungssystem
CN118836772A (zh) * 2024-08-21 2024-10-25 中国航空工业集团公司北京长城计量测试技术研究所 一种基于光纤低相干干涉的三维形貌测量装置及方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321501A (en) * 1991-04-29 1994-06-14 Massachusetts Institute Of Technology Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample
US6134003A (en) * 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US5491524A (en) * 1994-10-05 1996-02-13 Carl Zeiss, Inc. Optical coherence tomography corneal mapping apparatus
US5644642A (en) * 1995-04-03 1997-07-01 Carl Zeiss, Inc. Gaze tracking using optical coherence tomography
ATA107495A (de) * 1995-06-23 1996-06-15 Fercher Adolf Friedrich Dr Kohärenz-biometrie und -tomographie mit dynamischem kohärentem fokus
US5892583A (en) * 1997-08-21 1999-04-06 Li; Ming-Chiang High speed inspection of a sample using superbroad radiation coherent interferometer

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