JP4416400B2 - 抗原特異的ｔ−細胞の機能的精製のための可逆的ｍｈｃ多量体染色法 - Google Patents
抗原特異的ｔ−細胞の機能的精製のための可逆的ｍｈｃ多量体染色法 Download PDFInfo
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- Health & Medical Sciences (AREA)
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- Cell Biology (AREA)
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- Urology & Nephrology (AREA)
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- General Engineering & Computer Science (AREA)
- Ecology (AREA)
- Toxicology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00128634A EP1227321A1 (en) | 2000-12-28 | 2000-12-28 | Reversible MHC multimer staining for functional purification of antigen-specific T cells |
| PCT/EP2001/015353 WO2002054065A2 (en) | 2000-12-28 | 2001-12-28 | Reversible mhc multimer staining for functional purification of antigen-specific t cells |
Publications (3)
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| JP2004525354A JP2004525354A (ja) | 2004-08-19 |
| JP2004525354A5 JP2004525354A5 (cg-RX-API-DMAC7.html) | 2008-12-18 |
| JP4416400B2 true JP4416400B2 (ja) | 2010-02-17 |
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| EP (2) | EP1227321A1 (cg-RX-API-DMAC7.html) |
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| CA (1) | CA2467434C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002054065A2 (cg-RX-API-DMAC7.html) |
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| WO2008140573A2 (en) | 2006-11-15 | 2008-11-20 | Invitrogen Dynal As | Methods for reversibly binding a biotin compound to a support |
| EP2155782A2 (en) | 2007-03-26 | 2010-02-24 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| EP2167536A1 (en) | 2007-07-03 | 2010-03-31 | Dako Denmark A/S | Mhc multimers, methods for their generation, labeling and use |
| US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| CA2697193C (en) | 2007-09-14 | 2017-06-06 | Adimab, Inc. | Rationally designed, synthetic antibody libraries and uses therefor |
| WO2009039854A2 (en) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
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| US4948590A (en) * | 1987-06-09 | 1990-08-14 | Yale University | Avidin or streptavidin conjugated liposomes |
| DE4237113B4 (de) * | 1992-11-03 | 2006-10-12 | "Iba Gmbh" | Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins |
| US5595881A (en) * | 1994-08-09 | 1997-01-21 | Anergen, Inc. | Method for the detection of antigen presenting cells |
| US6022951A (en) * | 1995-04-11 | 2000-02-08 | Univ Boston | Streptavidin mutants |
| JP2000500733A (ja) * | 1995-09-01 | 2000-01-25 | ユニバーシティ オブ ワシントン | 相互作用分子結合体 |
| DE19641876B4 (de) * | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| US5985658A (en) * | 1997-11-14 | 1999-11-16 | Health Research Incorporated | Calmodulin-based cell separation technique |
| FR2841905B1 (fr) * | 2002-07-05 | 2004-09-03 | Centre Nat Rech Scient | Fragments fab mutants de l'anticorps anti-cd4 chimere 13b8.2 et leurs applications |
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| US8298782B2 (en) | 2012-10-30 |
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