JP4372545B2 - オーファンｇタンパク質共役型レセプターｇｐｒ８６の天然リガンドと使用方法 - Google Patents

オーファンｇタンパク質共役型レセプターｇｐｒ８６の天然リガンドと使用方法 Download PDF

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JP4372545B2
JP4372545B2 JP2003519412A JP2003519412A JP4372545B2 JP 4372545 B2 JP4372545 B2 JP 4372545B2 JP 2003519412 A JP2003519412 A JP 2003519412A JP 2003519412 A JP2003519412 A JP 2003519412A JP 4372545 B2 JP4372545 B2 JP 4372545B2
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gpr86
adp
cells
activity
binding
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JP2005500053A5 (enExample
JP2005500053A (ja
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コミュニ，ディディエ
スアレツ，ナタリー
デセックス，ミッシェル
ブレジイロン，ステファン
ラノイ，ヴィンセント
パーメンテール，マルコ
ボエイナエムス，ジーン・マリー
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Ogeda BV
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Euroscreen SA
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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JP2003519412A 2001-08-07 2002-08-06 オーファンｇタンパク質共役型レセプターｇｐｒ８６の天然リガンドと使用方法 Expired - Lifetime JP4372545B2 (ja)

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Application Number Priority Date Filing Date Title
US09/924,125 US6946244B2 (en) 2001-08-07 2001-08-07 Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13)
PCT/EP2002/008761 WO2003014731A2 (en) 2001-08-07 2002-08-06 The natural ligand for orphan g protein coupled receptor gpr86 and methods of use

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JP2005500053A JP2005500053A (ja) 2005-01-06
JP2005500053A5 JP2005500053A5 (enExample) 2006-01-12
JP4372545B2 true JP4372545B2 (ja) 2009-11-25

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US (3) US6946244B2 (enExample)
EP (1) EP1421377B1 (enExample)
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AT (1) ATE324585T1 (enExample)
CA (1) CA2453486C (enExample)
DE (1) DE60210989T2 (enExample)
DK (1) DK1421377T3 (enExample)
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AU2003266238A1 (en) * 2002-08-05 2004-02-25 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with ovarian cancer g-protein coupled receptor 1 (ogr-1)
GB2394286A (en) * 2002-09-17 2004-04-21 Innovab Ltd An assay for adp using an adp binding protein
WO2004082571A2 (en) * 2003-03-18 2004-09-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 86 (gpr86)
GB0312844D0 (en) * 2003-06-04 2003-07-09 Paradigm Therapeutics Ltd Use of compounds in medicine
GB0312845D0 (en) * 2003-06-04 2003-07-09 Paradigm Therapeutics Ltd Use of componds in medicine
AU2005258934A1 (en) 2004-07-01 2006-01-12 Paradigm Therapeutics Limited Use of the receptor GPR86
JP4926952B2 (ja) * 2004-07-01 2012-05-09 武田薬品工業株式会社 Ｇｐｒ８６受容体の使用
ES2322727B1 (es) 2005-07-28 2010-04-22 Universidad Del Pais Vasco Metodo para cuantificar la union receptor acoplado a proteina g (gpcr)-proteina g mediante el empleo de un array de membranas celulares.
EP2036567A3 (en) 2005-12-06 2009-12-09 P2-Science APS Modulation of the P2Y2 receptor pathway
GB0817166D0 (en) * 2008-09-19 2008-10-29 Medical Res Council Sensor
US11376269B2 (en) 2016-05-06 2022-07-05 Inserm Pharmaceutical compositions for the treatment of chemoresistant acute myeloid leukemia (AML)

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US6162899A (en) * 1997-10-23 2000-12-19 Smithkline Beecham Corporation Human HNEAA81 receptor
CA2239255A1 (en) * 1997-10-23 1999-04-23 Smithkline Beecham Corporation Cdna clone hneaa81 that encodes a human 7-transmembrane receptor
ATE301673T1 (de) * 1998-11-20 2005-08-15 Arena Pharm Inc Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
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EP1421377A2 (en) 2004-05-26
WO2003014731A3 (en) 2004-02-19
CA2453486A1 (en) 2003-02-20
US20040005629A1 (en) 2004-01-08
US20030050235A1 (en) 2003-03-13
US7422846B2 (en) 2008-09-09
DE60210989D1 (de) 2006-06-01
DK1421377T3 (da) 2006-08-28
ATE324585T1 (de) 2006-05-15
ES2262819T3 (es) 2006-12-01
US20060078918A1 (en) 2006-04-13
DE60210989T2 (de) 2006-12-14
WO2003014731A2 (en) 2003-02-20
WO2003014731B1 (en) 2004-03-25
US6946244B2 (en) 2005-09-20
JP2005500053A (ja) 2005-01-06
CA2453486C (en) 2011-09-27
EP1421377B1 (en) 2006-04-26

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