JP4352613B2 - 血管新生促進剤及び血管新生作用増強剤 - Google Patents
血管新生促進剤及び血管新生作用増強剤 Download PDFInfo
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- JP4352613B2 JP4352613B2 JP2000508370A JP2000508370A JP4352613B2 JP 4352613 B2 JP4352613 B2 JP 4352613B2 JP 2000508370 A JP2000508370 A JP 2000508370A JP 2000508370 A JP2000508370 A JP 2000508370A JP 4352613 B2 JP4352613 B2 JP 4352613B2
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- hydrogen atom
- pyridazinone
- halogen atom
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23264497 | 1997-08-28 | ||
PCT/JP1998/003820 WO1999011268A1 (fr) | 1997-08-28 | 1998-08-26 | Agents promoteurs et agents potentialisateurs de la neovascularisation |
Publications (1)
Publication Number | Publication Date |
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JP4352613B2 true JP4352613B2 (ja) | 2009-10-28 |
Family
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Family Applications (1)
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JP2000508370A Expired - Fee Related JP4352613B2 (ja) | 1997-08-28 | 1998-08-26 | 血管新生促進剤及び血管新生作用増強剤 |
Country Status (13)
Families Citing this family (30)
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---|---|---|---|---|
AU768825B2 (en) * | 1998-12-07 | 2004-01-08 | Nissan Chemical Industries Ltd. | Remedial agent for erectile dysfunction |
KR20060125816A (ko) * | 2003-12-26 | 2006-12-06 | 닛산 가가쿠 고교 가부시키 가이샤 | 호중구증다 억제제 |
BRPI0507518A8 (pt) * | 2004-02-09 | 2015-12-01 | Nissan Chemical Ind Ltd | Inibidor de hiperplasia vascular da íntima |
WO2007011707A2 (en) | 2005-07-15 | 2007-01-25 | Micell Technologies, Inc. | Polymer coatings containing drug powder of controlled morphology |
WO2007011708A2 (en) | 2005-07-15 | 2007-01-25 | Micell Technologies, Inc. | Stent with polymer coating containing amorphous rapamycin |
ES2540059T3 (es) | 2006-04-26 | 2015-07-08 | Micell Technologies, Inc. | Recubrimientos que contienen múltiples fármacos |
CA2667228C (en) | 2006-10-23 | 2015-07-14 | Micell Technologies, Inc. | Holder for electrically charging a substrate during coating |
US11426494B2 (en) | 2007-01-08 | 2022-08-30 | MT Acquisition Holdings LLC | Stents having biodegradable layers |
EP2111184B1 (en) | 2007-01-08 | 2018-07-25 | Micell Technologies, Inc. | Stents having biodegradable layers |
WO2008105260A1 (ja) * | 2007-02-28 | 2008-09-04 | Ltt Bio-Pharma Co., Ltd. | 下肢切断手術の予後を改善する治療剤 |
US9433516B2 (en) | 2007-04-17 | 2016-09-06 | Micell Technologies, Inc. | Stents having controlled elution |
AU2008256684B2 (en) | 2007-05-25 | 2012-06-14 | Micell Technologies, Inc. | Polymer films for medical device coating |
US8685432B2 (en) * | 2008-03-25 | 2014-04-01 | University Of Utah Research Foundation | Controlled release tissue graft combination biomaterials |
AU2009251504B2 (en) | 2008-04-17 | 2013-09-05 | Micell Technologies, Inc. | Stents having bioabsorbable layers |
AU2009270849B2 (en) | 2008-07-17 | 2013-11-21 | Micell Technologies, Inc. | Drug delivery medical device |
WO2011009096A1 (en) | 2009-07-16 | 2011-01-20 | Micell Technologies, Inc. | Drug delivery medical device |
US8834913B2 (en) | 2008-12-26 | 2014-09-16 | Battelle Memorial Institute | Medical implants and methods of making medical implants |
CA2756386C (en) | 2009-03-23 | 2019-01-15 | Micell Technologies, Inc. | Drug delivery medical device |
JP2012522589A (ja) | 2009-04-01 | 2012-09-27 | ミシェル テクノロジーズ,インコーポレイテッド | 被覆ステント |
US11369498B2 (en) | 2010-02-02 | 2022-06-28 | MT Acquisition Holdings LLC | Stent and stent delivery system with improved deliverability |
US8795762B2 (en) | 2010-03-26 | 2014-08-05 | Battelle Memorial Institute | System and method for enhanced electrostatic deposition and surface coatings |
US9554888B2 (en) | 2010-04-20 | 2017-01-31 | University Of Utah Research Foundation | Phase separation sprayed scaffold |
US10232092B2 (en) | 2010-04-22 | 2019-03-19 | Micell Technologies, Inc. | Stents and other devices having extracellular matrix coating |
EP2593039B1 (en) | 2010-07-16 | 2022-11-30 | Micell Technologies, Inc. | Drug delivery medical device |
WO2012166819A1 (en) | 2011-05-31 | 2012-12-06 | Micell Technologies, Inc. | System and process for formation of a time-released, drug-eluting transferable coating |
CA2841360A1 (en) | 2011-07-15 | 2013-01-24 | Micell Technologies, Inc. | Drug delivery medical device |
US10188772B2 (en) | 2011-10-18 | 2019-01-29 | Micell Technologies, Inc. | Drug delivery medical device |
EP2953581B1 (en) | 2013-02-05 | 2020-09-16 | University of Utah Research Foundation | Implantable devices for bone or joint defects |
AU2014248508B2 (en) | 2013-03-12 | 2018-11-08 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
AU2014265460B2 (en) | 2013-05-15 | 2018-10-18 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0482208B1 (en) * | 1990-04-25 | 2000-07-19 | Nissan Chemical Industries Ltd. | Pyridazinone derivative |
CA2063055A1 (en) * | 1991-05-22 | 1992-11-23 | Jacob Eyal | Peptides having thrombospondin-like activity and their therapeutic use |
JP3666042B2 (ja) | 1994-01-25 | 2005-06-29 | 日産化学工業株式会社 | ピリダジノン誘導体 |
IL112695A (en) | 1994-02-22 | 1999-04-11 | Green Cross Corp | Pharmaceutical compositions containing pyridazinone derivatives |
-
1998
- 1998-08-26 US US09/486,327 patent/US6284758B1/en not_active Expired - Lifetime
- 1998-08-26 WO PCT/JP1998/003820 patent/WO1999011268A1/ja active IP Right Grant
- 1998-08-26 ES ES98940584T patent/ES2247716T3/es not_active Expired - Lifetime
- 1998-08-26 KR KR1020007001968A patent/KR100559192B1/ko not_active IP Right Cessation
- 1998-08-26 DK DK98940584T patent/DK1025847T3/da active
- 1998-08-26 AT AT98940584T patent/ATE307584T1/de active
- 1998-08-26 DE DE69832089T patent/DE69832089T2/de not_active Expired - Lifetime
- 1998-08-26 CN CNB988105799A patent/CN1142779C/zh not_active Expired - Fee Related
- 1998-08-26 AU AU88862/98A patent/AU8886298A/en not_active Abandoned
- 1998-08-26 JP JP2000508370A patent/JP4352613B2/ja not_active Expired - Fee Related
- 1998-08-26 CA CA002301852A patent/CA2301852C/en not_active Expired - Fee Related
- 1998-08-26 EP EP98940584A patent/EP1025847B1/en not_active Expired - Lifetime
- 1998-08-27 TW TW087114142A patent/TW490303B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2301852A1 (en) | 1999-03-11 |
DE69832089D1 (de) | 2005-12-01 |
CN1142779C (zh) | 2004-03-24 |
CN1277553A (zh) | 2000-12-20 |
US6284758B1 (en) | 2001-09-04 |
CA2301852C (en) | 2007-07-10 |
KR20010023331A (ko) | 2001-03-26 |
KR100559192B1 (ko) | 2006-03-13 |
TW490303B (en) | 2002-06-11 |
DE69832089T2 (de) | 2006-07-20 |
EP1025847A1 (en) | 2000-08-09 |
WO1999011268A1 (fr) | 1999-03-11 |
ES2247716T3 (es) | 2006-03-01 |
DK1025847T3 (da) | 2006-02-13 |
ATE307584T1 (de) | 2005-11-15 |
EP1025847B1 (en) | 2005-10-26 |
EP1025847A4 (en) | 2003-01-08 |
AU8886298A (en) | 1999-03-22 |
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