DE69832089D1 - Mittel zur förderung und verstärkung der neovaskularisierung - Google Patents

Mittel zur förderung und verstärkung der neovaskularisierung

Info

Publication number
DE69832089D1
DE69832089D1 DE69832089T DE69832089T DE69832089D1 DE 69832089 D1 DE69832089 D1 DE 69832089D1 DE 69832089 T DE69832089 T DE 69832089T DE 69832089 T DE69832089 T DE 69832089T DE 69832089 D1 DE69832089 D1 DE 69832089D1
Authority
DE
Germany
Prior art keywords
angiogenesis
neovascularization
promoting
reinforcing
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69832089T
Other languages
English (en)
Other versions
DE69832089T2 (de
Inventor
Yasuhiro Egi
Hideaki Kido
Kazutaka Hayashi
Yoshiji Kubo
Norifumi Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Application granted granted Critical
Publication of DE69832089D1 publication Critical patent/DE69832089D1/de
Publication of DE69832089T2 publication Critical patent/DE69832089T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DE69832089T 1997-08-28 1998-08-26 Mittel zur förderung und verstärkung der neovaskularisierung Expired - Lifetime DE69832089T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23264497 1997-08-28
JP23264497 1997-08-28
PCT/JP1998/003820 WO1999011268A1 (fr) 1997-08-28 1998-08-26 Agents promoteurs et agents potentialisateurs de la neovascularisation

Publications (2)

Publication Number Publication Date
DE69832089D1 true DE69832089D1 (de) 2005-12-01
DE69832089T2 DE69832089T2 (de) 2006-07-20

Family

ID=16942531

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832089T Expired - Lifetime DE69832089T2 (de) 1997-08-28 1998-08-26 Mittel zur förderung und verstärkung der neovaskularisierung

Country Status (13)

Country Link
US (1) US6284758B1 (de)
EP (1) EP1025847B1 (de)
JP (1) JP4352613B2 (de)
KR (1) KR100559192B1 (de)
CN (1) CN1142779C (de)
AT (1) ATE307584T1 (de)
AU (1) AU8886298A (de)
CA (1) CA2301852C (de)
DE (1) DE69832089T2 (de)
DK (1) DK1025847T3 (de)
ES (1) ES2247716T3 (de)
TW (1) TW490303B (de)
WO (1) WO1999011268A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL143530A0 (en) * 1998-12-07 2002-04-21 Nissan Chemical Ind Ltd Pyridazinone derivatives
CN1897952B (zh) * 2003-12-26 2010-12-08 日产化学工业株式会社 中性白细胞增多抑制剂
RU2339381C2 (ru) * 2004-02-09 2008-11-27 Ниссан Кемикал Индастриз, Лтд. Ингибитор гиперплазии интимы сосудов
US8298565B2 (en) 2005-07-15 2012-10-30 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
PL2019657T3 (pl) 2006-04-26 2015-10-30 Micell Technologies Inc Powłoki zawierające wiele leków
CN101678388B (zh) 2006-10-23 2013-12-11 米歇尔技术公司 用于在涂覆过程中为基底充电的保持器
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
CA2679712C (en) 2007-01-08 2016-11-15 Micell Technologies, Inc. Stents having biodegradable layers
CN101622003B (zh) * 2007-02-28 2012-03-21 日本株式会社Ltt生物医药 改善下肢截肢手术的预后的治疗剂
US9433516B2 (en) 2007-04-17 2016-09-06 Micell Technologies, Inc. Stents having controlled elution
EP2170418B1 (de) 2007-05-25 2016-03-16 Micell Technologies, Inc. Polymerfilme zur beschichtung von medizinprodukten
US8685432B2 (en) * 2008-03-25 2014-04-01 University Of Utah Research Foundation Controlled release tissue graft combination biomaterials
MX2010011485A (es) 2008-04-17 2011-03-01 Micell Technologies Inc Stents que contienen capas bioadsorbibles.
AU2009270849B2 (en) 2008-07-17 2013-11-21 Micell Technologies, Inc. Drug delivery medical device
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
US8834913B2 (en) 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
WO2010111232A2 (en) 2009-03-23 2010-09-30 Micell Technologies, Inc. Drug delivery medical device
JP2012522589A (ja) 2009-04-01 2012-09-27 ミシェル テクノロジーズ,インコーポレイテッド 被覆ステント
EP2531140B1 (de) 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent und stenteinsatzsystem mit verbesserter einsetzbarkeit
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
WO2011133183A1 (en) 2010-04-20 2011-10-27 University Of Utah Research Foundation Phase separation sprayed scaffold
EP2560576B1 (de) 2010-04-22 2018-07-18 Micell Technologies, Inc. Stents und andere vorrichtungen mit beschichtung durch eine extrazelluläre matrix
EP2593039B1 (de) 2010-07-16 2022-11-30 Micell Technologies, Inc. Medizinische wirkstofffreisetzungsvorrichtung
WO2012166819A1 (en) 2011-05-31 2012-12-06 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
CA2841360A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
EP2953581B1 (de) 2013-02-05 2020-09-16 University of Utah Research Foundation Implantierbare vorrichtungen für knochen- oder gelenkdefekte
CN110269959A (zh) 2013-03-12 2019-09-24 脉胜医疗技术公司 可生物吸收的生物医学植入物
CA2912387C (en) 2013-05-15 2019-04-16 Micell Technologies, Inc. Bioabsorbable biomedical implants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA27031A1 (uk) * 1990-04-25 2000-02-28 Ніссан Кемікал Індастріз Лтд Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові
CA2063055A1 (en) * 1991-05-22 1992-11-23 Jacob Eyal Peptides having thrombospondin-like activity and their therapeutic use
JP3666042B2 (ja) * 1994-01-25 2005-06-29 日産化学工業株式会社 ピリダジノン誘導体
IL112695A (en) * 1994-02-22 1999-04-11 Green Cross Corp Pharmaceutical compositions containing pyridazinone derivatives

Also Published As

Publication number Publication date
KR100559192B1 (ko) 2006-03-13
CN1142779C (zh) 2004-03-24
JP4352613B2 (ja) 2009-10-28
EP1025847B1 (de) 2005-10-26
CA2301852C (en) 2007-07-10
DE69832089T2 (de) 2006-07-20
EP1025847A1 (de) 2000-08-09
EP1025847A4 (de) 2003-01-08
US6284758B1 (en) 2001-09-04
ES2247716T3 (es) 2006-03-01
KR20010023331A (ko) 2001-03-26
CN1277553A (zh) 2000-12-20
DK1025847T3 (da) 2006-02-13
TW490303B (en) 2002-06-11
AU8886298A (en) 1999-03-22
CA2301852A1 (en) 1999-03-11
WO1999011268A1 (fr) 1999-03-11
ATE307584T1 (de) 2005-11-15

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