JP4336451B2 - Ｈｌａ−ｅ結合 - Google Patents
Ｈｌａ−ｅ結合 Download PDFInfo
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- JP4336451B2 JP4336451B2 JP2000523554A JP2000523554A JP4336451B2 JP 4336451 B2 JP4336451 B2 JP 4336451B2 JP 2000523554 A JP2000523554 A JP 2000523554A JP 2000523554 A JP2000523554 A JP 2000523554A JP 4336451 B2 JP4336451 B2 JP 4336451B2
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| CA2456196A1 (en) * | 2001-07-31 | 2003-02-13 | Karl Petter Soderstrom | Compositions and methods for modulation of immune responses |
| US20040072262A1 (en) | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
| ATE405591T1 (de) * | 2003-08-26 | 2008-09-15 | Univ Danmarks Tekniske | Kontinuierliches verfahren zur anordnung von makromolekulären substanzen und die anschliessende aufnahme und isolierung einer makromolekulären anordnung, sowie ein für dieses verfahren geeignetes system |
| WO2005111624A2 (en) * | 2004-05-07 | 2005-11-24 | Beckman Coulter, Inc. | Mhc bridging system for detecting ctl-mediated lysis of antigen presenting cells |
| WO2006009838A2 (en) | 2004-06-17 | 2006-01-26 | Beckman Coulter, Inc. | Mycobacterium tuberculosis epitopes and methods of use thereof |
| HUE026107T2 (en) | 2004-12-28 | 2016-05-30 | Innate Pharma | Monoclonal antibody to NKG2A |
| ES2385754T3 (es) * | 2006-06-22 | 2012-07-31 | Novo Nordisk A/S | Receptores heterodiméricos solubles y usos de estos |
| WO2008009545A1 (en) | 2006-06-30 | 2008-01-24 | Novo Nordisk A/S | Anti-nkg2a antibodies and uses thereof |
| JP5774312B2 (ja) | 2008-01-24 | 2015-09-09 | ノボ・ノルデイスク・エー／エス | ヒト化抗ヒトｎｋｇ２ａモノクローナル抗体 |
| AU2012268939B2 (en) | 2011-06-17 | 2017-05-04 | Novo Nordisk A/S | Selective elimination of erosive cells |
| WO2014037422A1 (en) | 2012-09-04 | 2014-03-13 | Inven2 As | Selective and controlled expansion of educated nk cells |
| JP6433480B2 (ja) * | 2013-03-12 | 2018-12-05 | サンガモ セラピューティクス， インコーポレイテッド | Ｈｌａを修飾するための方法および組成物 |
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| EP3811970A1 (en) * | 2014-03-15 | 2021-04-28 | Novartis AG | Regulatable chimeric antigen receptor |
| US10857219B2 (en) * | 2014-03-28 | 2020-12-08 | The Board Of Regents Of The University Of Oklahoma | Compositions comprising soluble HLA/M. tuberculosis-specific ligand complexes and methods of production and use thereof |
| AU2015259877B2 (en) | 2014-05-15 | 2021-02-25 | National University Of Singapore | Modified natural killer cells and uses thereof |
| DK3193929T3 (da) | 2014-09-16 | 2019-08-19 | Innate Pharma | Behandlingsregimer ved anvendelse af anti-nkg2a-antistoffer |
| JP6767362B2 (ja) | 2014-09-16 | 2020-10-14 | イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． | リンパ球における阻害経路の中和 |
| BR112017005390A2 (pt) | 2014-09-17 | 2017-12-12 | Novartis Ag | células citotóxicas alvo com receptores quiméricos para imunoterapia adotiva |
| SG10202006685XA (en) | 2014-10-23 | 2020-08-28 | Innate Pharma | Treatment of Cancers Using Anti-NKG2A Agents |
| PL3405495T3 (pl) | 2016-01-21 | 2021-10-11 | Innate Pharma | Neutralizacja szlaków inhibitorowych w limfocytach |
| CN110809580A (zh) * | 2017-01-24 | 2020-02-18 | 安贝科思生物制剂公司 | 用于靶向癌症中包含非典型hla-i和新抗原的复合体的方法和组合物 |
| CN117384929A (zh) | 2017-03-27 | 2024-01-12 | 新加坡国立大学 | 一种编码由细胞表达的嵌合受体的多核苷酸 |
| RU2019128544A (ru) | 2017-03-27 | 2021-04-28 | Нэшнл Юниверсити Оф Сингапур | Линии стимулирующих клеток для ex vivo размножения и активации клеток-натуральных киллеров |
| AU2019219454A1 (en) * | 2018-02-09 | 2020-08-27 | National University Of Singapore | Activating chimeric receptors and uses thereof in natural killer cell immunotherapy |
| US20200399377A1 (en) * | 2018-02-23 | 2020-12-24 | Abexxa Biologics Inc. | Combination cancer therapy with anti-cancer agents and antibodies targeting a complex comprising non-classical hla-i and neoantigen |
| US11464840B2 (en) | 2018-02-26 | 2022-10-11 | Swey-Shen Chen | Universal non-classical MHC I vaccines: HLA-E-restricted antigenic peptides as universal vaccines to treat allergy, inflammation, autoimmune and infectious diseases, and cancers |
| EA202092147A1 (ru) | 2018-03-13 | 2021-03-04 | Иннейт Фарма | Лечение рака головы и шеи |
| EP3539552A1 (en) * | 2018-03-16 | 2019-09-18 | Deutsches Rheuma-Forschungszentrum Berlin | Activation and expansion of nkg2c+ nk cells |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| SG11202104969RA (en) | 2018-11-16 | 2021-06-29 | Bristol Myers Squibb Co | Anti-nkg2a antibodies and uses thereof |
| CA3121128A1 (en) * | 2018-12-02 | 2020-06-11 | Fate Therapeutics, Inc. | Immunotherapies using enhanced ipsc derived effector cells |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | ANTI-CD19 CHEMERIC ANTIGEN RECEPTORS AND THEIR USE IN IMMUNOTHERAPY |
| GB201909509D0 (en) * | 2019-07-02 | 2019-08-14 | Immunocore Ltd | Peptide-MHC complexes |
| JP2023543835A (ja) | 2020-09-30 | 2023-10-18 | ドレン バイオ， インコーポレイテッド | 抗ｃｄ９４抗体及びその使用方法 |
| EP4388012A4 (en) * | 2021-08-20 | 2025-09-17 | Univ Duke | ANTIBODIES TARGETING HLA-E-HOST PEPTIDE COMPLEXES AND THEIR USES |
| WO2024036303A2 (en) * | 2022-08-11 | 2024-02-15 | The Trustees Of The University Of Pennsylvania | Universal t cells and compositions and methods of use thereof |
| WO2024206190A1 (en) * | 2023-03-24 | 2024-10-03 | Duke University | Antibodies that target hla-e-host peptide complexes and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03112486A (ja) * | 1989-09-22 | 1991-05-14 | Olympus Optical Co Ltd | Ｈｌａ―ｂ３５遺伝子およびｄｎａプローブ並びに形質転換細胞 |
| JPH03112485A (ja) * | 1989-09-22 | 1991-05-14 | Olympus Optical Co Ltd | Ｈｌａ―ｃ遺伝子およびｄｎａプローブ並びに形質転換細胞 |
| JPH03112487A (ja) * | 1989-09-22 | 1991-05-14 | Olympus Optical Co Ltd | ＨＬＡ―Ｂｗ５３遺伝子およびＤＮＡプローブ並びに形質転換細胞 |
| GB9725764D0 (en) * | 1997-12-04 | 1998-02-04 | Isis Innovation | HLA-E binding |
-
1997
- 1997-12-04 GB GBGB9725764.6A patent/GB9725764D0/en not_active Ceased
-
1998
- 1998-12-04 EP EP98959027A patent/EP1036327B1/en not_active Expired - Lifetime
- 1998-12-04 AT AT98959027T patent/ATE438096T1/de not_active IP Right Cessation
- 1998-12-04 EP EP09165917A patent/EP2144065A1/en not_active Withdrawn
- 1998-12-04 US US09/555,555 patent/US7410767B1/en not_active Expired - Fee Related
- 1998-12-04 DE DE69841020T patent/DE69841020D1/de not_active Expired - Lifetime
- 1998-12-04 JP JP2000523554A patent/JP4336451B2/ja not_active Expired - Lifetime
- 1998-12-04 WO PCT/GB1998/003686 patent/WO1999028748A2/en not_active Ceased
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2008
- 2008-04-25 US US12/109,990 patent/US20080274475A1/en not_active Abandoned
- 2008-12-10 JP JP2008314107A patent/JP4437160B2/ja not_active Expired - Lifetime
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- 2009-08-21 JP JP2009191564A patent/JP5268828B2/ja not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| GB9725764D0 (en) | 1998-02-04 |
| JP2010024233A (ja) | 2010-02-04 |
| JP2009106299A (ja) | 2009-05-21 |
| DE69841020D1 (de) | 2009-09-10 |
| US7410767B1 (en) | 2008-08-12 |
| EP1036327B1 (en) | 2009-07-29 |
| ATE438096T1 (de) | 2009-08-15 |
| JP2002513541A (ja) | 2002-05-14 |
| US20080274475A1 (en) | 2008-11-06 |
| WO1999028748A3 (en) | 1999-12-23 |
| EP1036327A2 (en) | 2000-09-20 |
| US20150361180A1 (en) | 2015-12-17 |
| EP2144065A1 (en) | 2010-01-13 |
| JP5268828B2 (ja) | 2013-08-21 |
| JP2013081478A (ja) | 2013-05-09 |
| WO1999028748A2 (en) | 1999-06-10 |
| JP4437160B2 (ja) | 2010-03-24 |
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