JP4284177B2 - 脳卒中および他の虚血性症状の治療用ｈｄｌ - Google Patents
脳卒中および他の虚血性症状の治療用ｈｄｌ Download PDFInfo
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- JP4284177B2 JP4284177B2 JP2003522564A JP2003522564A JP4284177B2 JP 4284177 B2 JP4284177 B2 JP 4284177B2 JP 2003522564 A JP2003522564 A JP 2003522564A JP 2003522564 A JP2003522564 A JP 2003522564A JP 4284177 B2 JP4284177 B2 JP 4284177B2
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31360501P | 2001-08-20 | 2001-08-20 | |
| EP01120026A EP1285662A1 (en) | 2001-08-20 | 2001-08-20 | Reconstituted HDL for the treatment of stroke and ischemic conditions |
| PCT/EP2002/009294 WO2003018047A2 (en) | 2001-08-20 | 2002-08-20 | Hdl for the treatment of stroke and other ischemic conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005501110A JP2005501110A (ja) | 2005-01-13 |
| JP2005501110A5 JP2005501110A5 (enExample) | 2005-12-22 |
| JP4284177B2 true JP4284177B2 (ja) | 2009-06-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003522564A Expired - Fee Related JP4284177B2 (ja) | 2001-08-20 | 2002-08-20 | 脳卒中および他の虚血性症状の治療用ｈｄｌ |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040266660A1 (enExample) |
| EP (1) | EP1425031B8 (enExample) |
| JP (1) | JP4284177B2 (enExample) |
| AT (1) | ATE396736T1 (enExample) |
| AU (1) | AU2002340825B2 (enExample) |
| CA (1) | CA2457840C (enExample) |
| DE (1) | DE60226881D1 (enExample) |
| ES (1) | ES2304452T3 (enExample) |
| WO (1) | WO2003018047A2 (enExample) |
| ZA (1) | ZA200401360B (enExample) |
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| CN1668645A (zh) * | 2002-05-17 | 2005-09-14 | 埃斯佩里安医疗公司 | 治疗缺血再灌注的方法和组合物 |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| WO2007000924A1 (ja) * | 2005-06-28 | 2007-01-04 | Osaka University | プログラニュリン活性を抑制または促進する物質を含む医薬組成物、およびプログラニュリン活性を抑制または促進する物質のスクリーニング方法 |
| US20070110751A1 (en) * | 2005-10-25 | 2007-05-17 | Maclellan Robb | Compositions and methods for reducing infarct size |
| JP5601750B2 (ja) * | 2007-03-01 | 2014-10-08 | シーエスエル、リミテッド | 糖尿病患者の内皮機能異常の治療 |
| AU2007200908B2 (en) * | 2007-03-01 | 2012-08-16 | Csl Limited | Treatment of endothelial dysfunction in diabetic patients |
| CN102802618B (zh) | 2009-06-25 | 2014-06-18 | 泰特拉有限公司 | 烟酸和米曲肼的治疗组合 |
| WO2011006994A1 (en) | 2009-07-16 | 2011-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Hdl comprising a therapeutic agent and use in therapy |
| US12419839B2 (en) | 2009-10-09 | 2025-09-23 | Signablok, Inc. | Methods and compositions for targeted delivery of protein fragments |
| WO2011044545A2 (en) | 2009-10-09 | 2011-04-14 | Sigalov Alexander B | Methods and compositions for targeted imaging |
| US10894098B2 (en) | 2012-04-09 | 2021-01-19 | Signablok, Inc. | Methods and compositions for targeted imaging |
| US20120189612A1 (en) * | 2011-01-25 | 2012-07-26 | The Cleveland Clinic Foundation | Compositions and methods for treating cancer while preventing or reducing cardiotoxicity and/or cardiomyopathy |
| LT2673296T (lt) | 2011-02-07 | 2019-02-25 | Cerenis Therapeutics Holding Sa | Lipoproteino kompleksai ir jų gamyba ir jų panaudojimai |
| US20140171365A1 (en) * | 2011-03-25 | 2014-06-19 | The Trustees Of Columbia University In The City Of New York | Pegylated human hdl particle and process for production thereof |
| EP2853259A1 (en) | 2013-09-30 | 2015-04-01 | Université Pierre et Marie Curie (Paris 6) | Reconstituted high density lipoproteins composition and uses thereof |
| RU2016144908A (ru) | 2014-05-02 | 2018-06-05 | Серени Терапеутикс Холдинг Са | Маркеры hdl-терапии |
| TW201919712A (zh) | 2017-08-10 | 2019-06-01 | 法商塞勒尼斯醫療控股公司 | 運送子(cargomers) |
| US20190046608A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding Sa | Apomers |
| WO2021191266A1 (en) | 2020-03-25 | 2021-09-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Aerosolization of hdl for the treatment of lung infections |
| KR20230004605A (ko) | 2020-04-16 | 2023-01-06 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 급성 상태를 치료하는 방법 |
| CA3197168A1 (en) | 2020-10-01 | 2022-04-07 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| US12599677B2 (en) | 2020-10-05 | 2026-04-14 | Northwestern University | Targeted PH sensitive liposomes |
| CA3216226A1 (en) * | 2021-04-15 | 2022-10-20 | Abionyx Pharma Sa | Use of lipid binding protein-based complexes in organ preservation solutions |
| US20250230208A1 (en) | 2022-04-06 | 2025-07-17 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CN119317440A (zh) | 2022-04-06 | 2025-01-14 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗白细胞增多、内皮功能障碍和心脏炎的方法 |
| WO2023237935A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
| CA3258787A1 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | METHODS OF TREATMENT OF HYPERINFLAMMATORY DISEASES USING LIPID-BINDING PROTEIN COMPLEXES |
| KR20260010675A (ko) | 2023-01-13 | 2026-01-21 | 아비오닉스 파마 에스에이 | 지질 결합 단백질 분자 치료 |
| IL327995A (en) | 2023-10-31 | 2026-06-01 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2026008645A1 (en) | 2024-07-02 | 2026-01-08 | Institut National de la Santé et de la Recherche Médicale | Aerosolization of apolipoprotein a1 nanoparticles enriched with alpha-1-antitrypsin for the treatment of pulmonary emphysema in patients suffering from alpha-1 antitrypsin deficiency |
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| DE19547648A1 (de) * | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
| EP1212065A4 (en) * | 1999-07-08 | 2004-02-11 | Tularik Inc | COMPILATIONS AND METHODS FOR INCREASING THE HDL CHOLESTEROL LEVEL |
| GB9919713D0 (en) * | 1999-08-19 | 1999-10-20 | Queen Mary & Westfield College | New medical use of high density lipoprotein |
| AUPQ429399A0 (en) | 1999-11-26 | 1999-12-23 | Heart Research Institute, The | Oxidized apolipoproteins and methods of use |
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- 2002-08-20 DE DE60226881T patent/DE60226881D1/de not_active Expired - Lifetime
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| EP1425031B1 (en) | 2008-05-28 |
| ZA200401360B (en) | 2005-08-31 |
| US20080108550A1 (en) | 2008-05-08 |
| EP1425031A2 (en) | 2004-06-09 |
| JP2005501110A (ja) | 2005-01-13 |
| AU2002340825B2 (en) | 2007-07-05 |
| US20040266660A1 (en) | 2004-12-30 |
| WO2003018047A2 (en) | 2003-03-06 |
| CA2457840C (en) | 2011-10-11 |
| CA2457840A1 (en) | 2003-03-06 |
| ATE396736T1 (de) | 2008-06-15 |
| WO2003018047A3 (en) | 2004-01-29 |
| ES2304452T3 (es) | 2008-10-16 |
| DE60226881D1 (de) | 2008-07-10 |
| US7491693B2 (en) | 2009-02-17 |
| HK1064304A1 (en) | 2005-01-28 |
| EP1425031B8 (en) | 2008-09-03 |
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