JP4215429B2 - 癌治療におけるヒアルロン酸 - Google Patents

癌治療におけるヒアルロン酸 Download PDF

Info

Publication number
JP4215429B2
JP4215429B2 JP2001548149A JP2001548149A JP4215429B2 JP 4215429 B2 JP4215429 B2 JP 4215429B2 JP 2001548149 A JP2001548149 A JP 2001548149A JP 2001548149 A JP2001548149 A JP 2001548149A JP 4215429 B2 JP4215429 B2 JP 4215429B2
Authority
JP
Japan
Prior art keywords
cancer
dna
hyaluronic acid
composition
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2001548149A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003518510A (ja
JP2003518510A5 (cg-RX-API-DMAC7.html
Inventor
シー. フィリップス,ニゲル
シー. フィリオン,マリオ
Original Assignee
バイオニケ ライフ サイエンシーズ インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオニケ ライフ サイエンシーズ インコーポレイテッド filed Critical バイオニケ ライフ サイエンシーズ インコーポレイテッド
Publication of JP2003518510A publication Critical patent/JP2003518510A/ja
Publication of JP2003518510A5 publication Critical patent/JP2003518510A5/ja
Application granted granted Critical
Publication of JP4215429B2 publication Critical patent/JP4215429B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2001548149A 1999-12-28 2000-12-28 癌治療におけるヒアルロン酸 Expired - Fee Related JP4215429B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17337599P 1999-12-28 1999-12-28
US60/173,375 1999-12-28
PCT/CA2000/001562 WO2001047561A1 (en) 1999-12-28 2000-12-28 Hyaluronic acid in the treatment of cancer

Publications (3)

Publication Number Publication Date
JP2003518510A JP2003518510A (ja) 2003-06-10
JP2003518510A5 JP2003518510A5 (cg-RX-API-DMAC7.html) 2008-05-29
JP4215429B2 true JP4215429B2 (ja) 2009-01-28

Family

ID=22631719

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001548149A Expired - Fee Related JP4215429B2 (ja) 1999-12-28 2000-12-28 癌治療におけるヒアルロン酸

Country Status (8)

Country Link
US (1) US7125858B2 (cg-RX-API-DMAC7.html)
EP (1) EP1250152B1 (cg-RX-API-DMAC7.html)
JP (1) JP4215429B2 (cg-RX-API-DMAC7.html)
AU (1) AU784356B2 (cg-RX-API-DMAC7.html)
CA (1) CA2395493C (cg-RX-API-DMAC7.html)
DK (1) DK1250152T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ520312A (cg-RX-API-DMAC7.html)
WO (1) WO2001047561A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220168403A1 (en) * 2020-07-17 2022-06-02 Geron Corporation Subcutaneous telomerase inhibitor compositions and methods for using same

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1140198B1 (en) 1999-01-13 2007-10-31 Alchemia Oncology Pty Limited Use of hyaluronan for the manufacture of a medicament for the enhancement of the efficacy of cytotoxic drugs
US20020091095A1 (en) * 1999-12-13 2002-07-11 Phillips Nigel C. Modulation of Fas and FasL expression
DE60036019T2 (de) * 1999-12-13 2008-05-29 Bioniche Life Sciences Inc., Belleville Synthetische oligonukleotide die therapeutisch nützlich sind
AUPQ879500A0 (en) * 2000-07-14 2000-08-10 Meditech Research Limited Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease
US9066919B2 (en) 2000-07-14 2015-06-30 Alchemia Oncology Pty Limited Hyaluronan as a chemo-sensitizer in the treatment of cancer
WO2002061085A2 (en) 2000-10-31 2002-08-08 Ryan James W Isolated genomic polynucleotide fragments from the p15 region of chromosome 11
US7087586B2 (en) * 2001-04-24 2006-08-08 Bioniche Life Sciences, Inc. Oligonucleotide compositions and their use to induce differentiation of cells
ITPD20020271A1 (it) 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
EP1625851A4 (en) 2003-05-16 2007-12-26 Bbk Bio Corp PREPARATION FOR PREVENTING CONTACT OF PATHOGEN BROOMS WITH A LIVING ORGANISM
US20060240084A1 (en) * 2005-04-20 2006-10-26 Xylos Corporation Microbial cellulose materials for use in transdermal drug delivery systems, method of manufacture and use
CA2616607C (en) * 2005-07-27 2015-06-02 Alchemia Oncology Pty Limited Therapeutic protocols using hyaluronan
EP1922077A4 (en) * 2005-09-07 2013-03-06 Alchemia Oncology Pty Ltd THERAPEUTIC COMPOSITIONS WITH HYALURON AND THERAPEUTIC ANTIBODIES AND TREATMENT PROCEDURES
CN101848702B (zh) 2006-12-01 2013-07-17 安特里奥公司 两亲实体纳米粒子
DE102009035586A1 (de) 2009-07-31 2011-02-03 Fresenius Kabi Deutschland Gmbh Intravesikale Instillationslösungen zur Behandlung von Blasenkrebs
NO2480669T3 (cg-RX-API-DMAC7.html) * 2009-09-25 2018-04-07
WO2012049654A1 (en) 2010-10-13 2012-04-19 Bioniche Life Sciences, Inc. Bacterial ribonucleic acid cell wall compositions and methods of making and using them
JP2016537685A (ja) * 2013-09-12 2016-12-01 ディーエスエム アイピー アセッツ ビー.ブイ. 眼球デバイス
EP3541358A1 (en) 2016-11-21 2019-09-25 Eirion Therapeutics, Inc. Transdermal delivery of large agents
WO2020056191A1 (en) 2018-09-13 2020-03-19 Eirion Therapeutics, Inc. Uses of plasminogen activator inhibitor 1 (pai-1) inhibitors
US12702790B2 (en) 2019-06-13 2026-08-11 Hollister Incorporated Reusable urinary catheter kits
LT3952973T (lt) 2019-06-13 2023-07-10 Hollister Incorporated Daugkartinio naudojimo šlapimo kateterio produktai
WO2020263859A1 (en) 2019-06-25 2020-12-30 Hollister Incorporated Reusable urinary catheter products
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
JP7500038B2 (ja) * 2019-08-27 2024-06-17 国立研究開発法人物質・材料研究機構 炎症性サイトカイン産生抑制材、ヒアルロン酸誘導体、及び、ヒアルロン酸誘導体の製造方法。
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172815A (en) * 1962-04-24 1965-03-09 Warner Lambert Pharmaceutical Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof
US4152423A (en) * 1971-11-19 1979-05-01 Agence Nationale De Valorisation De La Recherche (Anvar) Immunological agents
FR2160326B1 (cg-RX-API-DMAC7.html) * 1971-11-19 1975-02-07 Anvar
CA1020460A (en) * 1973-02-23 1977-11-08 Wellcome Foundation Limited (The) Isolation of immunostimulating glycopeptide from bacteria
US3976544A (en) * 1973-06-19 1976-08-24 The Agence Nationale De Valorisation De Le Recherche Water-soluble immunological adjuvants, in particular for vaccines, obtained from mycobacteria and related microorganisms and process for their extraction
FR2374042A1 (fr) * 1976-06-04 1978-07-13 Merieux Inst Nouveau medicament immunostimulant et son procede de preparation
JPS54140710A (en) * 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
DE3011461C2 (de) * 1980-03-25 1986-10-30 Dr. Madaus & Co, 5000 Köln Verwendung von Propionibakterien
US4520019A (en) * 1982-04-29 1985-05-28 Ribi Immunochem Research, Inc. Stable composition and preparation thereof
US4579941A (en) * 1982-08-13 1986-04-01 Mitsuitoatsu Chemicals, Inc. Thermally-denatured deoxyribonucleic acid MD-011 and antitumor agent
US4663306A (en) * 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
GB8404280D0 (en) * 1984-02-17 1984-03-21 Stanford J L Biological preparations
DE3408768A1 (de) 1984-03-09 1985-09-12 Bayer Ag, 5090 Leverkusen Immunstimulierende mittel
US4744984A (en) * 1985-10-08 1988-05-17 Vetrepharm Research, Inc. Antiviral immunotherapeutic agent and preparation thereof
DE3689071T2 (de) 1985-10-31 1994-02-10 Univ Australian Immunheilbehandlung.
US4877611A (en) * 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
US4837202A (en) 1987-09-14 1989-06-06 Pitman-Moore, Inc. Method for stimulating the immune system
DE3818054C2 (de) 1988-05-27 1994-02-17 Biotest Pharma Gmbh Verwendung einer Kombination aus einem Antigen bzw. einer Vakzine und humanem Interleukin zur Behandlung der Non-Responsiveness gegenüber immunologischen Defektzuständen
CA1340994C (en) * 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Treatment of conditions and disease
EP0952855B1 (en) * 1991-07-03 2005-07-27 Meditech Research Limited Use of hyaluronan in gene therapy
CA2122519C (en) 1994-04-29 2001-02-20 Rudolf Edgar Dr. Falk Cancer treatment and metastasis prevention
AU691797B2 (en) * 1993-01-29 1998-05-28 Vetrepharm, Inc. Immunotherapeutic composition
AU6362594A (en) 1993-03-10 1994-09-26 Miles Inc. Hyaluronic acid used as a cancer treatment
IN181358B (cg-RX-API-DMAC7.html) * 1995-02-14 1998-05-30 Bioniche Inc
AU1991097A (en) 1996-03-15 1997-10-01 Immunotherapy, Inc. Dialdehydes as immunostimulatory adjuvants and cross-linkers for producing immunogenic preparations and generating pressure and cross-linked treated cells for enhancing and augmenting the immune response against cancers, tumors and pathogenic diseases
CA2208924A1 (en) 1997-07-09 1999-01-09 Hyal Pharmaceutical Corporation Sparing paclitaxel by the use of hyaluronan
KR100533576B1 (ko) * 1997-08-05 2005-12-05 바이오니취 라이프 사이언시즈 인코포레이티드 세포증식 및 세포사멸 조절용 조성물 및 방법
NZ506406A (en) 1998-02-18 2002-11-26 Bioniche Life Sciences Inc Compositions comprising Mycobacterium phlei DNA and methods for its use in the treatment of bladder cancer
WO2000033875A1 (en) 1998-12-04 2000-06-15 Bioniche Life Sciences Inc. Chemotherapeutic composition and method
EP1140198B1 (en) * 1999-01-13 2007-10-31 Alchemia Oncology Pty Limited Use of hyaluronan for the manufacture of a medicament for the enhancement of the efficacy of cytotoxic drugs
CA2266188A1 (en) 1999-03-19 2000-09-19 Stephen Chizick Natural preparation for treatment of male pattern hair loss

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220168403A1 (en) * 2020-07-17 2022-06-02 Geron Corporation Subcutaneous telomerase inhibitor compositions and methods for using same

Also Published As

Publication number Publication date
EP1250152A1 (en) 2002-10-23
AU784356B2 (en) 2006-03-16
JP2003518510A (ja) 2003-06-10
US7125858B2 (en) 2006-10-24
CA2395493C (en) 2010-06-22
AU2336401A (en) 2001-07-09
DK1250152T3 (da) 2013-08-26
WO2001047561A1 (en) 2001-07-05
NZ520312A (en) 2003-08-29
US20030176381A1 (en) 2003-09-18
EP1250152B1 (en) 2013-05-15
CA2395493A1 (en) 2001-07-05

Similar Documents

Publication Publication Date Title
US7125858B2 (en) Hyaluronic acid in the treatment of cancer
Melero et al. Intratumoural administration and tumour tissue targeting of cancer immunotherapies
Zhao et al. In situ activation of STING pathway with polymeric SN38 for cancer chemoimmunotherapy
Wittig et al. MGN1703, an immunomodulator and toll-like receptor 9 (TLR-9) agonist: from bench to bedside
Sfondrini et al. Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer
CN103003427B (zh) 具有佐剂活性的新型核酸及其应用
Atik et al. Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells
ES2235839T3 (es) Uso de oligonucleotidos estabilizados para la preparacion de un medicamento de accion antitumoral.
Jordan et al. CpG-1826 immunotherapy potentiates chemotherapeutic and anti-tumor immune responses to metronomic cyclophosphamide in a preclinical glioma model
CN104812244A (zh) 增强癌症治疗中特异性免疫疗法的方法
MXPA04004998A (es) Metodos para tratar cancer mediante la utilizacion de una combinacion de un antagonista del factor inhibidor de celula dentritica derivado de tumor y un antagonista del receptor de tipo toll.
AU2021202582A1 (en) Nanoparticles for use as a therapeutic vaccine
Miyamoto et al. Designing an immunocyte-targeting delivery system by use of beta-glucan
Yao et al. Immunotherapy for lung cancer combining the oligodeoxynucleotides of TLR9 agonist and TGF-β2 inhibitor
JP6536964B2 (ja) 免疫賦活活性を有する核酸多糖複合体の抗腫瘍薬としての応用
Sfondrini et al. Prevention of spontaneous mammary adenocarcinoma in HER‐2/neu transgenic mice by foreign DNA
Mizuno et al. Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice
KR20250029913A (ko) 신호 조절 단백질 알파 (SIRPα) 유전자의 발현을 억제하기 위한 조성물 및 방법
Nielsen et al. TLR9: a double-dealing Toll-like receptor
WO2025171792A1 (zh) 抗肿瘤复合疫苗
JP2019163302A (ja) 免疫賦活活性を有する核酸多糖複合体の抗腫瘍薬としての応用
WO2022102694A1 (ja) 粒子径が制御された、ベータグルカンと核酸との複合体
CN114681402A (zh) 免疫刺激性脂质复合体、包含免疫刺激性脂质复合体的药物组合物以及其用途
CN101333237B (zh) 一种具有治疗乳腺癌作用的寡核苷酸
TWI701047B (zh) 具有免疫賦活活性之核酸多醣複合體作為抗腫瘤藥之應用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20060831

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20060831

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20060921

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070509

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070509

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080409

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20080409

A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20080508

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20080409

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080613

RD13 Notification of appointment of power of sub attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7433

Effective date: 20080808

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080908

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20081007

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20081104

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111114

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111114

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121114

Year of fee payment: 4

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121114

Year of fee payment: 4

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121114

Year of fee payment: 4

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121114

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131114

Year of fee payment: 5

LAPS Cancellation because of no payment of annual fees