JP4070815B2 - パピローマウイルス腫瘍および感染を治療するための医薬組成物 - Google Patents

パピローマウイルス腫瘍および感染を治療するための医薬組成物 Download PDF

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Publication number
JP4070815B2
JP4070815B2 JP50856898A JP50856898A JP4070815B2 JP 4070815 B2 JP4070815 B2 JP 4070815B2 JP 50856898 A JP50856898 A JP 50856898A JP 50856898 A JP50856898 A JP 50856898A JP 4070815 B2 JP4070815 B2 JP 4070815B2
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Japan
Prior art keywords
polypeptide
papillomavirus
region
dna fragment
pharmaceutical composition
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Expired - Fee Related
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JP50856898A
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English (en)
Japanese (ja)
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JP2000500662A5 (cg-RX-API-DMAC7.html
JP2000500662A (ja
Inventor
ジャン−マルク、バルー
ナディーヌ、ビズアルヌ
マリー−ポール、キニー
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Transgene SA
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Transgene SA
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
JP50856898A 1996-07-30 1997-07-29 パピローマウイルス腫瘍および感染を治療するための医薬組成物 Expired - Fee Related JP4070815B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9609584A FR2751879B1 (fr) 1996-07-30 1996-07-30 Composition pharmaceutique contre les tumeurs et infections a papillomavirus
FR96/09584 1996-07-30
PCT/FR1997/001412 WO1998004705A1 (fr) 1996-07-30 1997-07-29 Composition pharmaceutique contre les tumeurs et infections a papillomavirus

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007092639A Division JP4198735B2 (ja) 1996-07-30 2007-03-30 パピローマウイルス腫瘍および感染を治療するための医薬組成物

Publications (3)

Publication Number Publication Date
JP2000500662A JP2000500662A (ja) 2000-01-25
JP2000500662A5 JP2000500662A5 (cg-RX-API-DMAC7.html) 2004-11-18
JP4070815B2 true JP4070815B2 (ja) 2008-04-02

Family

ID=9494633

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50856898A Expired - Fee Related JP4070815B2 (ja) 1996-07-30 1997-07-29 パピローマウイルス腫瘍および感染を治療するための医薬組成物
JP2007092639A Expired - Fee Related JP4198735B2 (ja) 1996-07-30 2007-03-30 パピローマウイルス腫瘍および感染を治療するための医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007092639A Expired - Fee Related JP4198735B2 (ja) 1996-07-30 2007-03-30 パピローマウイルス腫瘍および感染を治療するための医薬組成物

Country Status (12)

Country Link
EP (2) EP0862634B2 (cg-RX-API-DMAC7.html)
JP (2) JP4070815B2 (cg-RX-API-DMAC7.html)
AT (2) ATE205881T1 (cg-RX-API-DMAC7.html)
AU (1) AU736720B2 (cg-RX-API-DMAC7.html)
CA (1) CA2234263C (cg-RX-API-DMAC7.html)
DE (2) DE69706825T3 (cg-RX-API-DMAC7.html)
DK (2) DK0862634T4 (cg-RX-API-DMAC7.html)
ES (2) ES2215805T3 (cg-RX-API-DMAC7.html)
FR (1) FR2751879B1 (cg-RX-API-DMAC7.html)
HK (1) HK1043809B (cg-RX-API-DMAC7.html)
PT (2) PT1149910E (cg-RX-API-DMAC7.html)
WO (1) WO1998004705A1 (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7494658B2 (en) 1998-02-20 2009-02-24 Medigene Ag Papilloma virus truncated L1 protein and fusion protein constructs
US20020039584A1 (en) 1998-02-20 2002-04-04 Medigene Ag Papilloma virus capsomere vaccine formulations and methods of use
US7182947B2 (en) 1998-02-20 2007-02-27 Medigene Ag Papillomavirus truncated L1 protein and fusion protein constructs
CA2229955C (en) 1998-02-20 2003-12-09 Medigene Gmbh Papilloma virus capsomere vaccine formulations and methods of use
US6926897B1 (en) 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
AU751970B2 (en) * 1998-06-26 2002-09-05 Aventis Pasteur Mucosal targeting immunisation
HUE037866T2 (hu) 2006-06-20 2018-09-28 Transgene Sa Eljárás poxvírusok és poxvírus-készítmények elõállítására
PT2382474E (pt) 2009-01-20 2015-06-03 Transgene Sa Icam-1 solúvel como biomarcador para a previsão de uma resposta terapêutica
WO2010108908A1 (en) 2009-03-24 2010-09-30 Transgene Sa Biomarker for monitoring patients
CN102395883B (zh) 2009-04-17 2015-12-02 特朗斯吉有限公司 用于监控患者的生物标志物
US8609392B2 (en) 2009-05-12 2013-12-17 Transgene S.A. Method for orthopoxvirus production and purification
CN102483405B (zh) 2009-07-10 2015-12-02 特朗斯吉有限公司 用于选择患者的生物标志物及相关方法
EP2456461A1 (en) 2009-07-21 2012-05-30 Transgene SA Enzymatic composition for the digestion of chicken embryos
TWI690322B (zh) 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
ES2753364T3 (es) 2014-12-01 2020-04-08 Transgene Sa Formulaciones líquidas estables de virus vaccinia
FR3042121A1 (fr) * 2015-10-08 2017-04-14 Jean-Marc Limacher Composition anti-tumorale
AU2018269319A1 (en) 2017-05-15 2019-11-07 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
WO2018211419A1 (en) 2017-05-15 2018-11-22 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
EP3847246A1 (en) 2018-09-06 2021-07-14 Bavarian Nordic A/S Storage improved poxvirus compositions
AU2021233167A1 (en) 2020-03-12 2022-09-22 Bavarian Nordic A/S Compositions improving poxvirus stability

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2643817B1 (fr) * 1989-03-06 1993-12-17 Transgene Sa Composition pharmaceutique, utile a titre preventif ou curatif contre les tumeurs induites par les papillomavirus
CA2038581A1 (en) 1990-03-20 1991-09-21 Martin Muller Seroreactive epitopes of human papillomavirus (hpv) 16 proteins
GB9113809D0 (en) * 1991-06-26 1991-08-14 Cancer Res Campaign Tech Papillomavirus l2 protein
DE122007000018I1 (de) * 1991-07-19 2007-05-24 Univ Queensland Polynukleotidabschnitt des HPV16-Genoms
US5618536A (en) * 1992-09-03 1997-04-08 The United States Of America As Represented By The Department Of Health And Human Services Chimeric papillomavirus-like particles
GB9306731D0 (en) * 1993-03-31 1993-05-26 Cancer Res Campaign Tech Vaccines
IL113817A (en) * 1994-06-30 2001-03-19 Merck & Co Inc Polynucleotide vaccne for papillomavirus
AU712714B2 (en) * 1994-10-03 1999-11-11 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Enhanced immune response by introduction of cytokine gene and/or costimulatory molecule B7 gene in a recombinant virus expressing system
GB9505784D0 (en) * 1995-03-22 1995-05-10 Lynxvale Ltd Anti-tumour treatment
FR2749323B1 (fr) * 1996-06-04 1998-07-10 Pasteur Merieux Serums Vacc Pseudo-particules virales utiles en tant que vecteur de delivrance d'acide nucleique

Also Published As

Publication number Publication date
HK1043809A1 (en) 2002-09-27
PT862634E (pt) 2002-03-28
EP0862634B1 (fr) 2001-09-19
DK0862634T3 (da) 2002-01-21
CA2234263A1 (fr) 1998-02-05
JP4198735B2 (ja) 2008-12-17
PT1149910E (pt) 2004-09-30
EP0862634A1 (fr) 1998-09-09
HK1043809B (zh) 2004-12-03
ES2215805T3 (es) 2004-10-16
ATE265535T1 (de) 2004-05-15
FR2751879A1 (fr) 1998-02-06
DK1149910T3 (da) 2004-08-02
WO1998004705A1 (fr) 1998-02-05
ATE205881T1 (de) 2001-10-15
AU3855297A (en) 1998-02-20
CA2234263C (fr) 2009-10-13
DE69728914T2 (de) 2005-04-07
DK0862634T4 (da) 2006-05-08
FR2751879B1 (fr) 1998-10-30
JP2007254474A (ja) 2007-10-04
AU736720B2 (en) 2001-08-02
JP2000500662A (ja) 2000-01-25
EP1149910B1 (fr) 2004-04-28
DE69706825T3 (de) 2006-08-24
ES2163795T3 (es) 2002-02-01
EP0862634B2 (fr) 2006-03-01
DE69706825D1 (de) 2001-10-25
DE69728914D1 (de) 2004-06-03
DE69706825T2 (de) 2002-05-02
EP1149910A1 (fr) 2001-10-31
ES2163795T5 (es) 2006-07-16

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