JP4005022B2 - 分散体からの粒子、とくに血液からの血球の分離方法および分離モジュール - Google Patents

分散体からの粒子、とくに血液からの血球の分離方法および分離モジュール Download PDF

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JP4005022B2
JP4005022B2 JP2003535890A JP2003535890A JP4005022B2 JP 4005022 B2 JP4005022 B2 JP 4005022B2 JP 2003535890 A JP2003535890 A JP 2003535890A JP 2003535890 A JP2003535890 A JP 2003535890A JP 4005022 B2 JP4005022 B2 JP 4005022B2
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JP2005505770A5 (enExample
JP2005505770A (ja
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エッフェンハウザー、カルロ
オクヴィルク、グレゴール
フィードラー、ヴォルフガング
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エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • G01N2015/055—Investigating sedimentation of particle suspensions in blood for hematocrite determination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
JP2003535890A 2001-10-12 2002-09-14 分散体からの粒子、とくに血液からの血球の分離方法および分離モジュール Expired - Fee Related JP4005022B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10150549A DE10150549A1 (de) 2001-10-12 2001-10-12 Verfahren und Trennmodul zum Abtrennen von Partikeln aus einer Dispersion, insbesondere von Blutkörperchen aus Blut
PCT/EP2002/010336 WO2003033096A2 (de) 2001-10-12 2002-09-14 Verfahren und trennmodul zum abtrennen von partikeln aus einer dispersion, insbesondere von blutkörperchen aus blut

Publications (3)

Publication Number Publication Date
JP2005505770A JP2005505770A (ja) 2005-02-24
JP2005505770A5 JP2005505770A5 (enExample) 2005-12-22
JP4005022B2 true JP4005022B2 (ja) 2007-11-07

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ID=7702370

Family Applications (1)

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JP2003535890A Expired - Fee Related JP4005022B2 (ja) 2001-10-12 2002-09-14 分散体からの粒子、とくに血液からの血球の分離方法および分離モジュール

Country Status (9)

Country Link
US (1) US7527740B2 (enExample)
EP (1) EP1434637B1 (enExample)
JP (1) JP4005022B2 (enExample)
AT (1) ATE317281T1 (enExample)
AU (1) AU2002340906A1 (enExample)
CA (1) CA2463223C (enExample)
DE (2) DE10150549A1 (enExample)
ES (1) ES2257574T3 (enExample)
WO (1) WO2003033096A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10313201A1 (de) * 2003-03-21 2004-10-07 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und mikrofluidisches Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Flüssigkeit, die Partikel enthält
TW200702292A (en) * 2005-02-28 2007-01-16 Careside Medical Llc A micro-fluidic fluid separation device and method
JP2007021465A (ja) * 2005-07-12 2007-02-01 Minoru Seki 粒子を連続的に濃縮・分離するための流路構造および方法
DE102005050167B4 (de) * 2005-10-19 2009-02-19 Advalytix Ag Konzentrationsverfahren, Konzentrationsvorrichtung und Reaktionsverfahren
CN101454664B (zh) * 2006-05-24 2013-08-21 国立大学法人京都大学 血浆分离用微流路
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) * 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
EP2276549A1 (en) * 2008-03-19 2011-01-26 Oncnosis Pharma Aie Method and apparatus for separating particles in a fluid
JP2010071857A (ja) * 2008-09-19 2010-04-02 Sekisui Chem Co Ltd 血漿分離装置
US8980106B2 (en) 2010-12-15 2015-03-17 Abbott Laboratories Apparatus and method for separation of whole blood into plasma or serum and cells
DE102012206371A1 (de) * 2012-04-18 2013-10-24 Siemens Ag Durchflusssystem mit einer Rückhaltestruktur für Partikel und dessen Verwendung
WO2014128960A1 (ja) * 2013-02-25 2014-08-28 株式会社メニコン マイクロ流体デバイス

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US3695942A (en) * 1970-12-02 1972-10-03 Amchem Prod Zirconium rinse for phosphate coated metal surfaces
US3791933A (en) 1971-02-25 1974-02-12 Geomet Rapid methods for assay of enzyme substrates and metabolites
US4148670A (en) * 1976-04-05 1979-04-10 Amchem Products, Inc. Coating solution for metal surface
FR2417537A1 (fr) * 1978-02-21 1979-09-14 Parker Ste Continentale Composition a base d'hafnium pour inhiber la corrosion des metaux
IT1111586B (it) * 1979-03-16 1986-01-13 Parker Italiana Composizioni protettive per superfici d'acciaio e processo per la loro preparazione
DE3029579C2 (de) 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
DE3274800D1 (en) 1981-02-05 1987-02-05 Asahi Chemical Ind Apparatus for separating blood components
US4457790A (en) * 1983-05-09 1984-07-03 Parker Chemical Company Treatment of metal with group IV B metal ion and derivative of polyalkenylphenol
US4470853A (en) * 1983-10-03 1984-09-11 Coral Chemical Company Coating compositions and method for the treatment of metal surfaces
JPS60201253A (ja) 1984-03-26 1985-10-11 Jeol Ltd 血漿採取装置
US5011551A (en) * 1988-12-22 1991-04-30 The United States Of America As Represented By The Secretary Of The Army Protective coating for steel surfaces and method of application
US5125989A (en) * 1989-04-21 1992-06-30 Henkel Corporation Method and composition for coating aluminum
US5656070A (en) * 1992-11-24 1997-08-12 Ensci Inc. Corrosion inhibiting compositions containing plant derived catechol complexes
US5380374A (en) * 1993-10-15 1995-01-10 Circle-Prosco, Inc. Conversion coatings for metal surfaces
EP0871539B1 (en) * 1995-06-16 2002-02-20 University of Washington Tangential flow planar microfabricated fluid filter
US5711996A (en) * 1995-09-28 1998-01-27 Man-Gill Chemical Company Aqueous coating compositions and coated metal surfaces
US5662746A (en) * 1996-02-23 1997-09-02 Brent America, Inc. Composition and method for treatment of phosphated metal surfaces
JP3903098B2 (ja) 1997-07-18 2007-04-11 富士フイルム株式会社 血液濾過方法
WO1999009042A2 (en) 1997-08-13 1999-02-25 Cepheid Microstructures for the manipulation of fluid samples
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Also Published As

Publication number Publication date
ATE317281T1 (de) 2006-02-15
EP1434637A2 (de) 2004-07-07
EP1434637B1 (de) 2006-02-08
JP2005505770A (ja) 2005-02-24
DE50205804D1 (de) 2006-04-20
WO2003033096A2 (de) 2003-04-24
AU2002340906A1 (en) 2003-04-28
CA2463223A1 (en) 2003-04-24
CA2463223C (en) 2009-08-25
ES2257574T3 (es) 2006-08-01
WO2003033096A3 (de) 2003-12-18
US20050029190A1 (en) 2005-02-10
DE10150549A1 (de) 2003-04-17
US7527740B2 (en) 2009-05-05

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