JP3999814B2 - エステラーゼ - Google Patents

エステラーゼ Download PDF

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Publication number
JP3999814B2
JP3999814B2 JP52941197A JP52941197A JP3999814B2 JP 3999814 B2 JP3999814 B2 JP 3999814B2 JP 52941197 A JP52941197 A JP 52941197A JP 52941197 A JP52941197 A JP 52941197A JP 3999814 B2 JP3999814 B2 JP 3999814B2
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JP
Japan
Prior art keywords
polynucleotide
seq
sequence
enzyme
array
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP52941197A
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English (en)
Japanese (ja)
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JP2001505403A (ja
Inventor
ロバートソン,ダン,イー.
マーフィー,デニス
レイド,ジョン
メイフィア,アンソニー,エム.
リンク,スチーブン
スワンソン,ロナルド,ブイ.
ワーレン,パトリック,ブイ.
コスモッカ,アンナ
カレン,ウォールター
Original Assignee
ディベルサ コーポレーション
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Publication of JP2001505403A publication Critical patent/JP2001505403A/ja
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Publication of JP3999814B2 publication Critical patent/JP3999814B2/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP52941197A 1996-02-16 1997-02-11 エステラーゼ Expired - Fee Related JP3999814B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/602,359 1996-02-16
US08/602,359 US5942430A (en) 1996-02-16 1996-02-16 Esterases
PCT/US1997/002039 WO1997030160A1 (en) 1996-02-16 1997-02-11 Esterases

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2003148286A Division JP2003339391A (ja) 1996-02-16 2003-05-26 エステラーゼ
JP2007140859A Division JP2007209359A (ja) 1996-02-16 2007-05-28 エステラーゼ

Publications (2)

Publication Number Publication Date
JP2001505403A JP2001505403A (ja) 2001-04-24
JP3999814B2 true JP3999814B2 (ja) 2007-10-31

Family

ID=24411043

Family Applications (4)

Application Number Title Priority Date Filing Date
JP52941197A Expired - Fee Related JP3999814B2 (ja) 1996-02-16 1997-02-11 エステラーゼ
JP2003148286A Pending JP2003339391A (ja) 1996-02-16 2003-05-26 エステラーゼ
JP2007140859A Pending JP2007209359A (ja) 1996-02-16 2007-05-28 エステラーゼ
JP2008013713A Pending JP2008109942A (ja) 1996-02-16 2008-01-24 エステラーゼ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2003148286A Pending JP2003339391A (ja) 1996-02-16 2003-05-26 エステラーゼ
JP2007140859A Pending JP2007209359A (ja) 1996-02-16 2007-05-28 エステラーゼ
JP2008013713A Pending JP2008109942A (ja) 1996-02-16 2008-01-24 エステラーゼ

Country Status (8)

Country Link
US (1) US5942430A (https=)
EP (2) EP1550721A3 (https=)
JP (4) JP3999814B2 (https=)
AT (1) ATE280230T1 (https=)
AU (1) AU716692C (https=)
CA (1) CA2246737A1 (https=)
DE (1) DE69731279D1 (https=)
WO (1) WO1997030160A1 (https=)

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US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
US7288400B2 (en) * 1996-02-16 2007-10-30 Verenium Corporation Nucleic acids encoding esterases and methods of making and using them
KR100570935B1 (ko) 1997-01-17 2006-04-13 맥시겐, 인크. 반복적 서열 재조합에 의한 전세포 및 유기체의 개량 방법
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
ES2168236T3 (es) 1997-04-09 2005-04-16 Danisco A/S Utilizacion de lipasa para mejorar las pastas de pan y los productos de panaderia.
US6541011B2 (en) 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
US7390619B1 (en) * 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
IL139093A0 (en) 1998-05-01 2001-11-25 Maxygen Inc Optimization of pest resistance genes using dna shuffling
ATE231186T1 (de) 1998-07-21 2003-02-15 Danisco Lebensmittel
CA2333914A1 (en) * 1998-08-12 2000-02-24 Maxygen, Inc. Dna shuffling to produce herbicide selective crops
JP2002522072A (ja) 1998-08-12 2002-07-23 マキシジェン, インコーポレイテッド 工業用化学薬品の製造のためのモノオキシゲナーゼ遺伝子のdnaシャッフリング。
JP2002526107A (ja) 1998-10-07 2002-08-20 マキシジェン, インコーポレイテッド マイコトキシンの解毒のための核酸を生成するためのdnaシャッフリング
WO2000028018A1 (en) 1998-11-10 2000-05-18 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimization of plant phenotypes
US6438561B1 (en) * 1998-11-19 2002-08-20 Navigation Technologies Corp. Method and system for using real-time traffic broadcasts with navigation systems
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6917882B2 (en) * 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US20030054390A1 (en) * 1999-01-19 2003-03-20 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US20070065838A1 (en) * 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
ES2341217T3 (es) 1999-01-19 2010-06-17 Maxygen, Inc. Recombinacion de acidos nucleicos mediada por oligonucleotidos.
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
JP2003524394A (ja) 1999-02-11 2003-08-19 マキシジェン, インコーポレイテッド ハイスループット質量分析法
JP3399518B2 (ja) * 1999-03-03 2003-04-21 インターナショナル・ビジネス・マシーンズ・コーポレーション 半導体構造およびその製造方法
US6531316B1 (en) 1999-03-05 2003-03-11 Maxyag, Inc. Encryption of traits using split gene sequences and engineered genetic elements
AU3391900A (en) 1999-03-05 2000-09-21 Maxygen, Inc. Encryption of traits using split gene sequences
EP1198565A1 (en) * 1999-07-07 2002-04-24 Maxygen Aps A method for preparing modified polypeptides
US20040002474A1 (en) * 1999-10-07 2004-01-01 Maxygen Inc. IFN-alpha homologues
US7430477B2 (en) * 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
US7115712B1 (en) * 1999-12-02 2006-10-03 Maxygen, Inc. Cytokine polypeptides
IL150291A0 (en) * 2000-01-11 2002-12-01 Maxygen Inc Integrated systems and methods for diversity generation and screening
AU2001241939A1 (en) * 2000-02-28 2001-09-12 Maxygen, Inc. Single-stranded nucleic acid template-mediated recombination and nucleic acid fragment isolation
US20010049104A1 (en) * 2000-03-24 2001-12-06 Stemmer Willem P.C. Methods for modulating cellular and organismal phenotypes
WO2002000897A2 (en) * 2000-06-23 2002-01-03 Maxygen, Inc. Novel chimeric promoters
EP1360290A2 (en) * 2000-06-23 2003-11-12 Maxygen, Inc. Co-stimulatory molecules
AU2001271912A1 (en) * 2000-07-07 2002-01-21 Maxygen, Inc. Molecular breeding of transposable elements
US6858422B2 (en) * 2000-07-13 2005-02-22 Codexis, Inc. Lipase genes
AU2001279134A1 (en) * 2000-07-31 2002-02-13 Maxygen, Inc. Nucleotide incorporating enzymes
US20020132308A1 (en) * 2000-08-24 2002-09-19 Mpep @ Page 300-M Novel constructs and their use in metabolic pathway engineering
JP2005502310A (ja) * 2000-12-01 2005-01-27 ディヴァーサ コーポレイション ハイドロラーゼ酵素および速度論的分割における用途
BR0209154A (pt) 2001-05-18 2004-07-20 Danisco Processo de preparação de uma massa com uma enzima
DE10149714A1 (de) * 2001-10-09 2003-04-30 Degussa Esterase EstA aus Rhodococcus sp.
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
DE602004030000D1 (de) 2003-01-17 2010-12-23 Danisco Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
WO2004066945A2 (en) * 2003-01-24 2004-08-12 Diversa Corporation Enzymes and the nucleic acids encoding them and methods for making and using them
WO2004076473A2 (en) * 2003-02-12 2004-09-10 Karo Bio Ab Androgen receptor interacting peptides
WO2005040370A2 (en) * 2003-09-30 2005-05-06 Goldschmidt Gmbh Thermostable hydrolase
US7718408B2 (en) 2003-12-24 2010-05-18 Danisco A/S Method
WO2008090395A1 (en) 2007-01-25 2008-07-31 Danisco A/S Production of a lipid acyltransferase from transformed bacillus licheniformis cells
GB0716126D0 (en) 2007-08-17 2007-09-26 Danisco Process
US7906307B2 (en) 2003-12-24 2011-03-15 Danisco A/S Variant lipid acyltransferases and methods of making
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
CN101052702B (zh) 2004-07-16 2013-01-09 杜邦营养生物科学有限公司 脂肪分解酶及其在食品工业中的应用
EP1987142A4 (en) * 2006-02-02 2009-07-15 Verenium Corp ESTERASES AND ASSOCIATED NUCLEIC ACIDS AND METHODS
JP4442660B2 (ja) 2007-08-10 2010-03-31 株式会社デンソー 車両システム
JP5506658B2 (ja) * 2008-02-26 2014-05-28 学校法人慶應義塾 好熱性古細菌由来エステラーゼを用いた光学活性カルボン酸の製造方法
WO2011119712A1 (en) * 2010-03-26 2011-09-29 E.I. Dupont De Nemours And Company Perhydrolase providing improved specific activity
CN102906256B (zh) 2010-03-26 2014-08-06 纳幕尔杜邦公司 用于纯化蛋白质的方法
US8389254B2 (en) 2010-03-26 2013-03-05 E.I. Du Pont De Nemours And Company Perhydrolase providing improved specific activity
WO2011119708A1 (en) 2010-03-26 2011-09-29 E.I. Dupont De Nemours And Company Perhydrolase providing improved specific activity
WO2011119714A1 (en) * 2010-03-26 2011-09-29 E.I. Dupont De Nemours And Company Perhydrolase providing improved specific activity
US8389255B2 (en) 2010-03-26 2013-03-05 E.I. De Pont De Nemours And Company Perhydrolase providing improved specific activity
CN103237895A (zh) * 2010-11-03 2013-08-07 耶路撒冷希伯来大学伊森姆研究发展有限公司 具有提高的糖化产率的转基因植物以及产生其的方法
CN109706133B (zh) * 2017-10-25 2022-12-27 上海交通大学 一组新型酯酶及其应用
CN110184254B (zh) * 2019-03-21 2022-07-22 复旦大学 一种具有高耐碱性的酯酶突变体及其应用

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JPH074256B2 (ja) * 1990-10-31 1995-01-25 栗田工業株式会社 リパーゼの活性発現を調節する遺伝子、ベクターおよびリパーゼの生産方法
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Also Published As

Publication number Publication date
CA2246737A1 (en) 1997-08-21
EP0880590A4 (en) 2000-11-08
JP2008109942A (ja) 2008-05-15
EP1550721A3 (en) 2007-04-18
JP2001505403A (ja) 2001-04-24
ATE280230T1 (de) 2004-11-15
DE69731279D1 (de) 2004-11-25
AU2119597A (en) 1997-09-02
EP0880590B1 (en) 2004-10-20
JP2007209359A (ja) 2007-08-23
EP1550721A2 (en) 2005-07-06
US5942430A (en) 1999-08-24
AU716692B2 (en) 2000-03-02
WO1997030160A1 (en) 1997-08-21
EP0880590A1 (en) 1998-12-02
AU716692C (en) 2001-08-23
JP2003339391A (ja) 2003-12-02

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