JP3978227B2 - 内部寄生生物を防除するための昆虫のニコチン性アセチルコリン受容体のアゴニスト及びアンタゴニスト - Google Patents

内部寄生生物を防除するための昆虫のニコチン性アセチルコリン受容体のアゴニスト及びアンタゴニスト Download PDF

Info

Publication number
JP3978227B2
JP3978227B2 JP50029796A JP50029796A JP3978227B2 JP 3978227 B2 JP3978227 B2 JP 3978227B2 JP 50029796 A JP50029796 A JP 50029796A JP 50029796 A JP50029796 A JP 50029796A JP 3978227 B2 JP3978227 B2 JP 3978227B2
Authority
JP
Japan
Prior art keywords
group
antagonists
alkyl
active compound
receptor agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP50029796A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10500699A (ja
Inventor
ノルベルト メンケ，
アヒム ハルダー，
テレンス ホプキンス，
Original Assignee
バイエル・アクチエンゲゼルシヤフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイエル・アクチエンゲゼルシヤフト filed Critical バイエル・アクチエンゲゼルシヤフト
Publication of JPH10500699A publication Critical patent/JPH10500699A/ja
Application granted granted Critical
Publication of JP3978227B2 publication Critical patent/JP3978227B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
JP50029796A 1994-06-07 1995-05-26 内部寄生生物を防除するための昆虫のニコチン性アセチルコリン受容体のアゴニスト及びアンタゴニスト Expired - Lifetime JP3978227B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4419814.0 1994-06-07
DE4419814A DE4419814A1 (de) 1994-06-07 1994-06-07 Endoparasitizide
PCT/EP1995/002014 WO1995033453A1 (de) 1994-06-07 1995-05-26 Agonisten und antagonisten der nicotinergen acetylcholinrezeptoren von insekten als endoparasitizide

Publications (2)

Publication Number Publication Date
JPH10500699A JPH10500699A (ja) 1998-01-20
JP3978227B2 true JP3978227B2 (ja) 2007-09-19

Family

ID=6519954

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50029796A Expired - Lifetime JP3978227B2 (ja) 1994-06-07 1995-05-26 内部寄生生物を防除するための昆虫のニコチン性アセチルコリン受容体のアゴニスト及びアンタゴニスト

Country Status (15)

Country Link
US (1) US5712295A (pt)
EP (1) EP0764022B1 (pt)
JP (1) JP3978227B2 (pt)
KR (1) KR100372348B1 (pt)
CN (1) CN1100537C (pt)
AT (1) ATE348604T1 (pt)
AU (1) AU704092B2 (pt)
BR (1) BR9507926A (pt)
CA (1) CA2192093C (pt)
DE (2) DE4419814A1 (pt)
DK (1) DK0764022T3 (pt)
ES (1) ES2279513T3 (pt)
MX (1) MX9606179A (pt)
WO (1) WO1995033453A1 (pt)
ZA (1) ZA954643B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4443888A1 (de) * 1994-12-09 1996-06-13 Bayer Ag Dermal applizierbare Formulierungen von Parasitiziden
US6426333B1 (en) * 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
DE19654079A1 (de) 1996-12-23 1998-06-25 Bayer Ag Endo-ekto-parasitizide Mittel
FR2761232B1 (fr) * 1997-03-26 2000-03-10 Rhone Merieux Procede et moyens d'eradication des puces dans les locaux habites par les petits mammiferes
DE19734665A1 (de) * 1997-08-11 1999-02-18 Bayer Ag Mittel gegen holzzerstörende Insekten
DE19807630A1 (de) * 1998-02-23 1999-08-26 Bayer Ag Wasserhaltige Mittel zur Bekämpfung parasitierender Insekten und Milben an Menschen
US6727228B2 (en) 2001-04-25 2004-04-27 Johnson & Johnson Consumer Companies, Inc. Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs
EP1835807A1 (en) * 2004-12-17 2007-09-26 Devgen N.V. Nematicidal compositions
US8110608B2 (en) 2008-06-05 2012-02-07 Ecolab Usa Inc. Solid form sodium lauryl sulfate (SLS) pesticide composition
US9820977B2 (en) * 2008-10-03 2017-11-21 Bayer Healthcare Llc Systemic treatment of blood-sucking and blood-consuming parasites by oral administration of a parasiticidal agent
US8968757B2 (en) * 2010-10-12 2015-03-03 Ecolab Usa Inc. Highly wettable, water dispersible, granules including two pesticides
CA2989391C (en) 2014-06-24 2023-03-14 John O'halloran Fish feed compositions containing a neonicotinoid for preventing and treating parasite infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA689474A (en) * 1964-06-23 Clarence H. Gleason Nicotine pamoate
JPS60172976A (ja) * 1984-02-16 1985-09-06 Nippon Tokushu Noyaku Seizo Kk ニトロメチレン誘導体，その製法及び殺虫，殺ダニ，殺センチユウ剤
ZW5085A1 (en) * 1984-04-13 1985-09-18 Nihon Tokushu Noyaku Seizo Kk Nitromethylene derivatives,intermediates thereof,processes for production thereof,and insecticides
DE3681465D1 (pt) * 1985-02-04 1991-10-24 Nihon Bayer Agrochem K.K., Tokio/Tokyo, Jp
JPH07121909B2 (ja) * 1986-09-10 1995-12-25 日本バイエルアグロケム株式会社 新規複素環式化合物及び殺虫剤
JP3023794B2 (ja) * 1989-05-17 2000-03-21 日本バイエルアグロケム株式会社 殺虫性ニトロ置換ヘテロ環式化合物
DE4232561A1 (de) * 1992-09-29 1994-03-31 Bayer Ag Bekämpfung von Fischparasiten

Also Published As

Publication number Publication date
DK0764022T3 (da) 2007-04-10
ES2279513T3 (es) 2007-08-16
WO1995033453A1 (de) 1995-12-14
MX9606179A (es) 1998-01-31
AU704092B2 (en) 1999-04-15
JPH10500699A (ja) 1998-01-20
BR9507926A (pt) 1997-11-11
EP0764022B1 (de) 2006-12-20
KR100372348B1 (ko) 2003-05-12
EP0764022A1 (de) 1997-03-26
CA2192093C (en) 2007-05-22
DE59511073D1 (de) 2007-02-01
AU2736495A (en) 1996-01-04
DE4419814A1 (de) 1995-12-14
ATE348604T1 (de) 2007-01-15
CA2192093A1 (en) 1995-12-14
US5712295A (en) 1998-01-27
CN1100537C (zh) 2003-02-05
CN1149827A (zh) 1997-05-14
ZA954643B (en) 1996-01-26

Similar Documents

Publication Publication Date Title
JP4104653B2 (ja) 殺内部寄生虫組成物
HU218569B (hu) Eljárás ciklusos depszipeptidek szulfonilezésére, az így előállított új vegyületek és parazitaellenes szerkénti alkalmazásuk
US5036069A (en) Anthelmintic active compound combinations
JPH0532631A (ja) 置換された２−メルカプトニコチン酸誘導体
HU226207B1 (en) Endoparaziticide compositions
JP3978227B2 (ja) 内部寄生生物を防除するための昆虫のニコチン性アセチルコリン受容体のアゴニスト及びアンタゴニスト
MXPA96006179A (en) Agonists and antagonists of the receptors of the nicotinic acid acetilcoline of insects for the control of endoparasi
CA2436832C (en) Crystal form of a cyclic depsipeptide having improved activity
NO328949B1 (no) Endoparasittiske sammensetninger, fremgangsmate for fremstilling derav samt anvendelse av cyklodepsipeptid
KR20010043957A (ko) 치환된 시클로옥타뎁시펩타이드
WO2003082836A1 (en) New dioxomorpholines for combating endoparasites
DE19515297A1 (de) Endoparasitizide Mittel
MXPA00011972A (en) Substituted cyclooctadepsipeptides

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060131

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20060427

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20060619

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060719

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060912

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20061212

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20070209

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070309

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20070612

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20070625

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100629

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100629

Year of fee payment: 3

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100629

Year of fee payment: 3

R360 Written notification for declining of transfer of rights

Free format text: JAPANESE INTERMEDIATE CODE: R360

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100629

Year of fee payment: 3

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100629

Year of fee payment: 3